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81. 发明申请

WO2014159584A2 VASO-OCCLUSIVE DEVICE DELIVERY SYSTEM 审中-公开
标题翻译： VASO-OCCLUSIVE设备交付系统
公开(公告)号：WO2014159584A2
公开(公告)日：2014-10-02
申请号：PCT/US2014/024291
申请日：2014-03-12
申请人： STRYKER CORPORATION , STRYKER NV OPERATIONS LIMITED
发明人： TEOH, Clifford , ODELL, Timothy , CHEN, Hancun , GUO, Lantao , MURPHY, Richard
IPC分类号： A61B17/12
CPC分类号： A61B17/1214 , A61B17/12031 , A61B17/12154 , A61B2017/12068 , A61B2017/12077 , A61B2017/1209
摘要： A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.
摘要翻译：血管闭塞装置递送组件包括具有近端和远端的推动器组件，设置在推动器组件的远端处的导电牺牲连接器和通过牺牲连接件固定到推动器组件的血管闭塞装置。推动器组件包括在其近端和远端之间延伸的第一和第二导体。牺牲链路电耦合在第一和第二导体之间，使得第一导体，牺牲链路和第二导体形成电路，并且当通过第一和第二导体通过牺牲链路施加崩解电流时，牺牲链路从而将附接构件和血管闭塞装置从推动器组件释放。

82. 发明申请

WO2014159445A1 SHAPE-MEMORY POLYMER FOAM DEVICE FOR TREATING ANEURYSMS 审中-公开
标题翻译：用于治疗神经病的形状记忆聚合物泡沫装置
公开(公告)号：WO2014159445A1
公开(公告)日：2014-10-02
申请号：PCT/US2014/023712
申请日：2014-03-11
申请人： LAWRENCE LIVERMORE NATIONAL SECURITY, LLC , THE TEXAS A&M UNIVERSITY SYSTEM , HARTMAN, Jonathan
发明人： HARTMAN, Jonathan , ORTEGA, Jason, M. , BENETT, William, J. , SMALL, Ward , WILSON, Thomas, S. , MAITLAND, Duncan, J.
IPC分类号： A61F2/06 , A61F2/82
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/12031 , A61B17/12181 , A61B2017/0061 , A61B2017/00871 , A61B2017/12077
摘要： A system for treating an aneurysm in a blood vessel or vein, wherein the aneurysm has a dome, an interior, and a neck. The system includes a shape memory polymer foam in the interior of the aneurysm between the dome and the neck. The shape memory polymer foam has pores that include a first multiplicity of pores having a first pore size and a second multiplicity of pores having a second pore size. The second pore size is larger than said first pore size. The first multiplicity of pores are located in the neck of the aneurysm. The second multiplicity of pores are located in the dome of the aneurysm.
摘要翻译：一种用于治疗血管或静脉中的动脉瘤的系统，其中所述动脉瘤具有圆顶，内部和颈部。该系统包括在圆顶和颈部之间的动脉瘤内部的形状记忆聚合物泡沫。形状记忆聚合物泡沫具有包括具有第一孔径的第一多个孔和具有第二孔径的第二多孔的孔。第二孔径大于所述第一孔径。第一个多孔的孔位于动脉瘤的颈部。孔的第二个多重性位于动脉瘤的圆顶。

83. 发明申请

WO2013162817A1 DELIVERY SYSTEM WITH HOOKS FOR RESHEATHABILITY 审中-公开
标题翻译：交付系统与HOOKS可持续发展
公开(公告)号：WO2013162817A1
公开(公告)日：2013-10-31
申请号：PCT/US2013/034196
申请日：2013-03-28
申请人： COVIDIEN LP
发明人： HUYNH, Andy
IPC分类号： A61F2/966 , A61F2/95
CPC分类号： A61F2/95 , A61B17/12118 , A61B2017/1205 , A61B2017/12054 , A61B2017/12077 , A61F2/844 , A61F2/86 , A61F2/90 , A61F2/91 , A61F2/966 , A61F2002/823 , A61F2002/9505 , A61F2002/9511 , A61F2002/9522 , A61F2002/9528 , A61F2002/9534 , A61F2002/9665
摘要： Described herein are flexible implantable devices or stents that can, for example, navigate the tortuous vessels of the neurovasculature. The devices can also conform to the shape of tortuous vessels of the vasculature. In some embodiments, the devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. Methods and structures are provided for adjusting, along a length of the device, the porosity of the device while maintaining a cross-sectional dimension. In some embodiments, small hooks releasably engage the stent at a proximal end and are able to resheath the stent by retracting a proximal retaining member where the hooks are coupled to. The hooks straighten, unfurl, or otherwise disengage the stent when either unrestrained by a catheter or when coming into contact with an external stimulus found in the patient's vasculature.
摘要翻译：这里描述的是可以例如导航神经血管系统的曲折血管的柔性可植入装置或支架。该装置还可以符合脉管系统曲折血管的形状。在一些实施例中，装置可引导血管内的血流远离动脉瘤或限制血液流动到动脉瘤。提供了方法和结构，用于在保持横截面尺寸的同时在装置的长度上调节装置的孔隙率。在一些实施例中，小钩在近端可释放地接合支架，并且能够通过缩回钩连接到其上的近侧保持构件来重新固定支架。钩子拉伸，展开或以其他方式脱离支架，当不受导管束缚或当与患者的脉管系统中发现的外部刺激接触时。

84. 发明申请

WO2006070641A1 医療用ワイヤー审中-公开
标题翻译：医疗用线
公开(公告)号：WO2006070641A1
公开(公告)日：2006-07-06
申请号：PCT/JP2005/023351
申请日：2005-12-20
申请人：国立大学法人京都大学 , 岩田博夫
发明人：岩田博夫
IPC分类号： A61B17/12 , A61M25/01
CPC分类号： B21F35/006 , A61B17/12013 , A61B17/12022 , A61B17/12145 , A61B2017/12077 , A61M25/09
摘要：　本発明は、導電性の線状部材の先端部に電気絶縁部材および接続部材を介して体内留置具が接続されてなり、接続部材が形状記憶合金からなり、線状部材に高周波電流が供給されると接続部材が熱されて変形し、該変形によって体内留置具が切り離されるように構成されていることを特徴とする医療用ワイヤーである。本医療用ワイヤーは、体内留置具の直接加熱による生体組織への侵襲がなく、容易に体内留置具とガイドワイヤーとを分離することができるという利点を有する。
摘要翻译：一种用于医疗用途的线，其中留置装置经由电绝缘构件和连接构件连接到导电线性构件的头部，所述连接构件由形状记忆体构成，并且构造成，当向线性构件供给高频电流时，连接构件被加热和变形以分离住住装置。当直接加热住宅装置时，用于医疗用途的线材不会对生物体组织产生热侵入，并且可以容易地将留置装置和导丝线分离。

85. 发明申请

WO2006017714A2 THERMAL TRANSITION METHODS AND DEVICES 审中-公开
标题翻译：热转换方法和设备
公开(公告)号：WO2006017714A2
公开(公告)日：2006-02-16
申请号：PCT/US2005/027842
申请日：2005-08-04
申请人： DELEGGE, Rebecca , KITCHEN, Michael, S.
发明人： DELEGGE, Rebecca , KITCHEN, Michael, S.
IPC分类号： A61F2/00
CPC分类号： A61F2/844 , A61B2017/00867 , A61B2017/1205 , A61B2017/12054 , A61B2017/12077 , A61F2/86 , A61F2/88 , A61F2210/0014 , A61F2210/0033 , A61F2210/0076 , C22F1/006
摘要： A method of sequentially transitioning a thermally active shape memory device progressively translocates the thermally active shape memory device through a first controlled temperature zone and through an additional controlled temperature zone. The thermally active shape memory device is thermally transitioned and changed in geometric shape as a result of thermal communication of the shape memory device with either or both of the controlled temperature zones to produce a transitioned thermally active shape memory device. Novel devices produced according to the method are also disclosed.
摘要翻译：依次转换热活性形状记忆装置的方法逐渐地将热活性形状记忆装置移位通过第一受控温度区并通过附加的控制温度区。热活性形状记忆装置由于形状记忆装置与受控温度区域中的任一个或两者的热连通而热转变并几何形状地改变，以产生转变的热活性形状记忆装置。还公开了根据该方法生产的新型器件。

86. 发明申请

WO2002096301A1 DETACHABLE TIP MICROCATHETER FOR USE OF LIQUID EMBOLIC AGENTS 审中-公开
标题翻译：用于液体代谢试剂的可分离提示微孔板
公开(公告)号：WO2002096301A1
公开(公告)日：2002-12-05
申请号：PCT/CA2002/000815
申请日：2002-06-03
申请人： RAYMOND, Jean
发明人： RAYMOND, Jean
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/00491 , A61B17/12113 , A61B17/1214 , A61B17/12186 , A61B2017/1205 , A61B2017/12059 , A61B2017/12068 , A61B2017/12077
摘要： The present invention relates to microcatheters (8) with a detachable tip for administering liquid embolic agents. The detachable tip microcatheter for use with liquid embolic agents in treating an aneurysm comprises a body adapted to be introduced in a vascular cavity; a detachable tip portion mounted on a distal end of the body; and a detaching mechanism (16) mounted between the tip and the body for detaching the tip from the body, the tip portion being adapted to be positioned in use in the aneurysm to introduce the embolic agent into the aneurysm.
摘要翻译：本发明涉及具有用于施用液体栓塞剂的可拆卸末端的微导管（8）。用于液体栓塞剂治疗动脉瘤的可拆卸尖端微导管包括适于引入血管腔的主体; 安装在所述主体的远端上的可拆卸顶端部分; 以及安装在所述尖端和所述主体之间用于将所述尖端从所述主体分离的分离机构（16），所述尖端部分适于被定位在所述动脉瘤中以将所述栓塞剂引入所述动脉瘤中。

87. 发明申请

WO01058366A1 INTRALUMINAL DELIVERY DEVICE 审中-公开
公开(公告)号：WO01058366A1
公开(公告)日：2001-08-16
申请号：PCT/US2001/000696
申请日：2001-01-09
IPC分类号： A61B17/00 , A61B17/12 , A61F2/84 , A61F2/06
CPC分类号： A61B17/12113 , A61B17/12 , A61B17/12022 , A61B17/12136 , A61B17/1214 , A61B2017/00477 , A61B2017/00867 , A61B2017/12068 , A61B2017/12077 , A61B2017/1209 , A61B2018/00005 , A61B2090/037 , A61F2002/9505 , A61F2002/9511
摘要： The apparatus (10) for deployment of a therapeutic device (14) such as a micro-coil detachably mounts the therapeutic device (14) to a distal portion of a pusher member (12). In one embodiment, the therapeutic device (14) is detachably mounted to the distal portion of the pusher member (12) by a tubular collar (24) that can be heated by a heater such as an electrical resistance coil (26) to expand the collar (24) and release and deploy the therapeutic device (14). The apparatus (40) for deployment of a therapeutic device (44) such as a micro-coil may also provide for a pusher member (42) and a connector fiber (64) for securing the therapeutic device (44) to the pusher member (42). The connector fiber (64) passes through a heater (66) within the distal portion of the pusher member (42), for heating and breaking the connector fiber (64) to release the therapeutic device (44) when a desired placement of the therapeutic device (44) within the vasculature is achieved.
摘要翻译：用于展开诸如微型线圈的治疗装置（14）的装置（10）将治疗装置（14）可拆卸地安装到推动器构件（12）的远侧部分。在一个实施例中，治疗装置（14）通过可被诸如电阻线圈（26）的加热器加热的管状套环（24）可拆卸地安装到推动器构件（12）的远端部分，以将（24）并释放和展开治疗装置（14）。用于展开诸如微型线圈的治疗装置（44）的装置（40）还可以提供用于将治疗装置（44）固定到推动器构件的推动器构件（42）和连接器纤维（64） 42）。连接器纤维（64）穿过推动器构件（42）的远端部分内的加热器（66），用于加热和断开连接器纤维（64）以释放治疗装置（44），当治疗剂实现脉管系统内的装置（44）。

88. 发明申请

WO0072781A2 INTRACORPOREAL OCCLUSIVE DEVICE 审中-公开
标题翻译： INTRACORPOREAL OCCLUSIVE设备
公开(公告)号：WO0072781A2
公开(公告)日：2000-12-07
申请号：PCT/US0015445
申请日：2000-06-02
申请人： SETHEL INTERVENTIONAL INC
发明人： MARKS MICHAEL P , ROSS MICHAEL
IPC分类号： A61B17/12 , A61B17/22 , A61M29/00 , A61F2/06
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/12109 , A61B17/12136 , A61B17/1214 , A61B17/12145 , A61B17/12163 , A61B17/12195 , A61B2017/00477 , A61B2017/00867 , A61B2017/12063 , A61B2017/12068 , A61B2017/12072 , A61B2017/12077 , A61B2017/22068 , A61B2017/22069 , A61M2025/1052
摘要： An intracorporeal space filling device (10) and a delivery system and method for using the device is disclosed. The space filling device (10) is preferably configured for percutaneous delivery from a peripheral conduit of a patient. The space filling device (10) has an elongated tubular (11) or interconnected bead structure (50) which may have a transmutable material (16, 55) disposed within it. The transmutable material (16, 55) can be altered from a non-rigid state to a rigid state by the application of various types of energy or by other suitable means. The space filling device (10) can be positioned by a delivery system and detached from the delivery system after desired positioning is achieved.
摘要翻译：公开了体内空间填充装置（10）以及使用该装置的输送系统和方法。空间填充装置（10）优选地构造成用于从患者的外围导管经皮递送。空间填充装置（10）具有细长管状（11）或互连的胎圈结构（50），其可设置在其内的可透过材料（16,55）。可透过材料（16,55）可以通过施加各种类型的能量或通过其它合适的方式从非刚性状态改变为刚性状态。空间填充装置（10）可以通过输送系统定位，并且在实现所需的定位之后从输送系统分离。

89. 发明申请

WO00012015A1 IMPLANT DELIVERY ASSEMBLY 审中-公开
标题翻译：植物输送组件
公开(公告)号：WO00012015A1
公开(公告)日：2000-03-09
申请号：PCT/US1999/019632
申请日：1999-08-27
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B2017/1205 , A61B2017/12072 , A61B2017/12077
摘要： An introducer for retaining an implant (22) placed within an implant delivery device (20) having a pusher (26) for displacing the implant (22) includes a tube (24) and a clamp (30). The interior of the tube (24) defines a passage (36) for guiding the movement of the pusher (26). The clamp (30) is made of a shape memory material disposed in the passage (36) about the pusher (26). The clamp (30) is normally operative to grip the pusher (26) to hold it in position relative to the tube (24) and further operative in response to an elevated temperature to release the pusher (26) for movement relative to the tube (24). The clamp (30) may be formed integrally with the tube (24) and may comprise at least one crimp or an annular ring surrounding the tube (24). The tube is tapered to be narrower at its distal end and may be formed of a shaped memory polymer material.
摘要翻译：用于保持放置在植入物输送装置（20）内的植入物（22）的导引器具有用于移动植入物（22）的推动器（26），包括管（24）和夹具（30）。管（24）的内部限定用于引导推动器（26）的运动的通道（36）。夹具（30）由形状记忆材料制成，形状记忆材料围绕推动器（26）布置在通道（36）中。夹具（30）通常可操作地夹紧推动器（26）以将其保持在相对于管（24）的适当位置，并且响应于升高的温度进一步操作以释放推动器（26）以相对于管移动 24）。夹具（30）可以与管（24）一体地形成，并且可以包括围绕管（24）的至少一个卷曲或环形圈。管在其远端是锥形的以更窄，并且可以由成形的记忆聚合物材料形成。

90. 发明申请

WO9956636A8 METHOD AND APPARATUS FOR OCCLUSION AND REINFORCEMENT OF ANEURYSMS 审中-公开
标题翻译：方法和装置用于压迫和加强神经元
公开(公告)号：WO9956636A8
公开(公告)日：2000-02-24
申请号：PCT/US9907952
申请日：1999-04-12
申请人： MICRUS CORP
发明人： KEN CHRISTOPHER G M , FERRERA DAVID A
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12036 , A61B17/12113 , A61B17/12168 , A61B17/12172 , A61B2017/12072 , A61B2017/12077
摘要： The vasoocclusive apparatus can be used in a method of interventional therapy and vascular surgery by inserting the apparatus into a portion of a vasculature, for treatment of a body vessel such as an aneurysm in conjunction with a secondary vasoocclusive device to be placed within the vessel. The vasoocclusive apparatus includes a plurality of strut members connected together at a central hub that extend from a collapsed position to an expanded configuration to cross the neck of the aneurysm, dividing the neck into smaller openings, allowing the deployment of the secondary vasoocclusive device within the aneurysm but preventing migration of the secondary vasoocclusive device from the aneurysm. The strut members can be made from a twisted cable of strands of a superelastic material, such as a shape memory nickel titanium alloy, with at least one radiopaque strand. A shape memory collar is provided for detachably mounting the vasoocclusive apparatus to a pusher member and for detaching the vasoocclusive apparatus for deployment when a desired placement within an aneurysm to be treated and out of a parent vessel is achieved.
摘要翻译：血管收缩装置可以用于介入治疗和血管手术的方法，将装置插入脉管系统的一部分中，用于与放置在血管内的次级血管收缩装置结合使用动脉瘤等体内血管。血管收缩装置包括在中心毂处连接在一起的多个支柱构件，所述支柱构件从折叠位置延伸到扩张构型以跨过动脉瘤的颈部，将颈部分成更小的开口，允许将第二血管收缩装置部署在内动脉瘤，但阻止二次血管收缩装置从动脉瘤的迁移。支柱构件可以由具有至少一个不透射线的超弹性材料（例如形状记忆镍钛合金）的股线的绞合电缆制成。提供了一种形状记忆颈圈，用于将血管收缩性装置可拆卸地安装到推动器构件上，并且当需要在待治疗的动脉瘤中并且在母体血管内达到期望的位置时，用于分离用于展开的血管收缩性装置。

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