专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明申请

US20190006160A1 INTELLIGENTLY CONTROLLED SPECTROMETER METHODS AND APPARATUS 审中-公开
公开(公告)号：US20190006160A1
公开(公告)日：2019-01-03
申请号：US16102227
申请日：2018-08-13
申请人： Mark A Osgood , Ching Wu
发明人： Mark A Osgood , Ching Wu
IPC分类号： H01J49/00 , H01J49/06 , H01J49/04 , C07B63/00 , G01N27/62
摘要： The present invention relates to improving the ability of a hyphenated instrument to analyze a sample benefiting from having the first instrument's analysis of the same sample. A fast switching mechanism can be used as the interface between an ion mobility spectrometer (IMS) and a mass spectrometer (MS) such that the obtained IMS spectrum is converted into a timing diagram that controls the vacuum inlet's size dynamically during analysis of a neutral and/or charged chemical and/or biological species such that a smaller pumping system can be used.

82. 发明申请

US20170365454A1 CHEMICALLY MODIFIED ION MOBILITY SEPARATION APPARATUS AND METHOD 审中-公开
公开(公告)号：US20170365454A1
公开(公告)日：2017-12-21
申请号：US15665421
申请日：2017-07-31
申请人： Ching Wu , Mark A. Osgood
发明人： Ching Wu , Mark A. Osgood
IPC分类号： H01J49/06 , C07B63/00 , G01N27/62 , H01J49/00
CPC分类号： H01J49/061 , C07B63/00 , G01N27/622 , H01J49/0027
摘要： An ion mobility spectrometry apparatus and method wherein ions are selected using an AC gate, then separated along a drift axis while providing a drift gas flow in a direction that is substantially neither in the direction of the drift axis nor opposite to the drift axis.

83. 发明授权

US09734998B2 AC gate ion filter method and apparatus 有权
公开(公告)号：US09734998B2
公开(公告)日：2017-08-15
申请号：US14992053
申请日：2016-01-11
申请人： Ching Wu , Mark A Osgood
发明人： Ching Wu , Mark A Osgood
IPC分类号： H01J49/26 , H01J49/06 , C07B63/00 , G01N27/62 , H01J49/00
CPC分类号： H01J49/061 , C07B63/00 , G01N27/622 , H01J49/0027
摘要： The present invention uses an AC voltage instead of DC voltage on an ion gate to filter/selectively pass ions. The ions that pass through the AC ion gate can be further separated in a spectrometric instrument. An ion mobility spectrometer using the AC ion gate can achieve better gating performance. For a time of flight ion mobility spectrometer with an AC ion gate, a narrow pulse of selected ions can be passed into a drift tube where they are separated based on their low field ion mobility. Moreover, when the AC voltage at the AC ion gate has a waveform as used for differential ion mobility spectrometry, the time of flight ion mobility spectrometer is converted into a two dimensional separation spectrometer, where ions are first separated based on their high field ion mobility and then further separated based on their low field ion mobility.

84. 发明申请

US20170097321A1 PRACTICAL ION MOBILITY SPECTROMETER APPARATUS AND METHODS FOR CHEMICAL AND/OR BIOLOGICAL DETECTION 审中-公开
公开(公告)号：US20170097321A1
公开(公告)日：2017-04-06
申请号：US15383736
申请日：2016-12-19
申请人： Ching Wu
发明人： Ching Wu
IPC分类号： G01N27/62 , H01J49/04 , H01J49/06
CPC分类号： G01N27/622 , H01J49/0031 , H01J49/004 , H01J49/0468 , H01J49/062
摘要： The present invention relates to ion mobility spectrometers. In one embodiment, the ion mobility spectrometer of the present invention uses a simplified ion mobility spectrometer design having helical resistive material to form substantially constant electric fields that guide ion movements. The drift tube for ion mobility spectrometers described herein is constructed with a non-conductive structure. This configuration provides a robust ion mobility spectrometer that is simple to build. One feature of the present invention is that the drift tube design described herein enables the ion mobility spectrometer to be built with a lower weight, lower power consumption, lower manufacturing cost, and free of sealants.

85. 发明授权

US09285343B2 Multi-dimentional ion mobility separator method and apparatus 有权
标题翻译：多维离子迁移分离方法及装置
公开(公告)号：US09285343B2
公开(公告)日：2016-03-15
申请号：US14214590
申请日：2014-03-14
申请人： Ching Wu , Christopher Hilton
发明人： Ching Wu , Christopher Hilton
IPC分类号： H01J49/40 , G01N27/62 , C07B63/00
CPC分类号： G01N27/624 , C07B63/00
摘要： One aspect of the present invention is to extract multiple ionic species in a FAIMS into one or more IMS drift tubes simultaneously. By adjusting FAIMS operational parameters, ions in FAIMS are detected on IMS detectors through separation in FAIMS and/or separation and collection in the IMS. This method provides a continuous separation of specific ions from an ion swarm by employing a high-field differential mobility analyzer (FAIMS) with a plurality of orthogonal transitions paths spaced incrementally along the electrodes which allow additional separation by a conventional IMS drift tube. The components of the sample can be collected or detected.
摘要翻译：本发明的一个方面是将FAIMS中的多个离子物质同时提取到一个或多个IMS漂移管中。通过调整FAIMS操作参数，通过FAIMS中的分离和/或IMS中的分离和收集，在IMS检测器上检测FAIMS中的离子。该方法通过采用具有多个正交跃迁路径的高场差分迁移率分析器（FAIMS）提供特定离子与离子群的连续分离，所述多个正交跃迁路径沿电极逐渐间隔开，这允许通过常规IMS漂移管进行额外分离。可以收集或检测样品的组分。

86. 发明申请

US20140367567A1 PARALLEL ION MASS AND ION MOBILITY ANALYSIS 有权
标题翻译：并行离子质量和离子移动分析
公开(公告)号：US20140367567A1
公开(公告)日：2014-12-18
申请号：US14338250
申请日：2014-07-22
申请人： Ching Wu , Clinton Alawn Krueger , Anthony Joseph Midey , Mark A. Osgood
发明人： Ching Wu , Clinton Alawn Krueger , Anthony Joseph Midey , Mark A. Osgood
IPC分类号： H01J49/00 , G01N30/72 , G01N27/62
CPC分类号： H01J49/009 , G01N27/622 , G01N30/7206 , G01N30/7233 , H01J49/0027 , H01J49/0031 , H01J49/004
摘要： The present invention relates to a parallel IMS and MS measurement method where a sample flow is split and delivered to an IMS and a MS in parallel. A parallel acquisition MS/IMS method is used to supplement LC-MS and or MS data by using a synchronized MS/IMS acquisition.
摘要翻译：本发明涉及一种并行的IMS和MS测量方法，其中采样流被并行地分离并传送到IMS和MS。并行采集MS / IMS方法用于通过使用同步的MS / IMS采集来补充LC-MS和/或MS数据。

87. 发明授权

US08785848B2 Parallel ion mass and ion mobility analysis 有权
标题翻译：平行离子质量和离子迁移率分析
公开(公告)号：US08785848B2
公开(公告)日：2014-07-22
申请号：US13792043
申请日：2013-03-09
申请人： Ching Wu , Clinton Alawn Krueger , Anthony Joseph Midey , Mark A. Osgood
发明人： Ching Wu , Clinton Alawn Krueger , Anthony Joseph Midey , Mark A. Osgood
IPC分类号： H01J49/26
CPC分类号： H01J49/009 , G01N27/622 , G01N30/7206 , G01N30/7233 , H01J49/0027 , H01J49/0031 , H01J49/004
摘要： The present invention relates to a parallel IMS and MS measurement method where a sample flow is split and delivered to an IMS and a MS in parallel. A parallel acquisition MS/IMS method is used to supplement LC-MS and or MS data by using a synchronized MS/IMS acquisition.
摘要翻译：本发明涉及一种并行的IMS和MS测量方法，其中采样流被并行地分离并传送到IMS和MS。并行采集MS / IMS方法用于通过使用同步的MS / IMS采集来补充LC-MS和/或MS数据。

88. 发明申请

US20120228491A1 HIGH PERFORMANCE ION MOBILITY SPECTROMETER APPARATUS AND METHODS 审中-公开
标题翻译：高性能离子移动光谱仪器和方法
公开(公告)号：US20120228491A1
公开(公告)日：2012-09-13
申请号：US13475993
申请日：2012-05-20
申请人： Ching Wu , Clinton Alawn Krueger , Anthony Joseph Midey , Mark A. Osgood
发明人： Ching Wu , Clinton Alawn Krueger , Anthony Joseph Midey , Mark A. Osgood
IPC分类号： H01J49/26
CPC分类号： G01N27/622
摘要： An ion mobility spectrometer wherein ions are separated along a drift axis while providing a drift gas flow in a direction that is substantially neither in the direction of the drift axis nor opposite to the drift axis. An ion mobility spectrometer and operation methods use a cross-directional gas flow in a drift tube and/or a segmented drift tube for pre-separation.
摘要翻译：离子迁移谱仪，其中离子沿着漂移轴线分离，同时在基本上不是在漂移轴线的方向上也不与漂移轴线相反的方向提供漂移气流。离子迁移谱仪和操作方法在漂移管和/或分段漂移管中使用横向气流用于预分离。

89. 发明授权

US08242442B2 Method and apparatus for chemical and biological sample separation 有权
标题翻译：化学和生物样品分离的方法和装置
公开(公告)号：US08242442B2
公开(公告)日：2012-08-14
申请号：US12695111
申请日：2010-01-27
申请人： Clinton Alawn Krueger , Ching Wu
发明人： Clinton Alawn Krueger , Ching Wu
IPC分类号： H01J49/26 , H01J49/00 , B01D59/44
CPC分类号： G01N27/622
摘要： The present invention involves a series of shifting reagents that selectively interact with a targeted functional group of biological molecules, pharmaceutical drugs, small molecules, chemicals, chemical agents, or explosives resulting in a structure selective based drift time shift in the IMS. The invention allows detecting and confirming samples using one or more ion mobility based spectrometers.
摘要翻译：本发明涉及一系列转移试剂，其选择性地与生物分子，药物，小分子，化学品，化学试剂或爆炸物的目标官能团相互作用，导致IMS中基于结构选择性的漂移时间偏移。本发明允许使用一种或多种基于离子迁移率的光谱仪检测和确认样品。

90. 发明申请

US20110283776A1 CHEMICAL SAMPLING AND MULTI-FUNCTION DETECTION METHODS AND APPARATUS 有权
标题翻译：化学取样和多功能检测方法及装置
公开(公告)号：US20110283776A1
公开(公告)日：2011-11-24
申请号：US13192334
申请日：2011-07-27
申请人： Ching Wu
发明人： Ching Wu
IPC分类号： G01N7/00
CPC分类号： G01N1/14 , G01N1/2214 , G01N1/405 , G01N2001/022 , G01N2001/028
摘要： This invention describes a sample collection method that could release and collect residues of explosives and other chemicals from a surface; the described method is implemented into a compact detection system that can be used as a “wand” for screening chemicals residues on human body. The wand configuration includes multiple functionalities for contrabands detection. The invention further describes a desorption method that can control chemical fragmentation pathway during desorption. The invention describes a combined detection device that detects trace chemicals and metal at the same time.
摘要翻译：本发明描述了可从表面释放和收集爆炸物和其他化学物质的残留物的样品收集方法; 所描述的方法被实现为紧凑的检测系统，其可以用作用于筛选人体上的化学物质残留物的“棒”。魔杖配置包括用于违禁品检测的多种功能。本发明还描述了一种在解吸过程中可以控制化学断裂途径的解吸附方法。本发明描述了一种同时检测微量化学物质和金属的组合检测装置。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式