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    • 85. 发明授权
    • Method, server and terminal for audio and video on demand
    • 音频和视频点播的方法,服务器和终端
    • US09204180B2
    • 2015-12-01
    • US13807512
    • 2011-06-28
    • Kedong ZhangXin Wang
    • Kedong ZhangXin Wang
    • H04N7/173H04N21/258H04N21/63H04L29/06H04L12/18
    • H04N21/25808H04L12/1854H04L65/4084H04L65/80H04N21/632
    • The present invention discloses a method, a server and a terminal of audio-video on demand (AVOD). The method comprises: receiving an audio-video resource request from an AVOD terminal; determining an assigned network the AVOD terminal belonging to in accordance with the audio-video resource request; determining resource nodes having the audio-video resource in the assigned network; generating a resource list according to the resource nodes having the audio-video resource in the assigned network; transmitting the resource list to the AVOD terminal so that the AVOD terminal acquires the audio-video resource according to the resource list. The present invention achieves both a smooth multiuser concurrent online AVOD and a reducing cost consumption of a network system.
    • 本发明公开了一种音视频点播(AVOD)的方法,服务器和终端。 该方法包括:从AVOD终端接收音频 - 视频资源请求; 确定属于根据音频 - 视频资源请求的AVOD终端的分配的网络; 确定在所分配的网络中具有所述音频 - 视频资源的资源节点; 根据具有所分配的网络中的音频 - 视频资源的资源节点生成资源列表; 将资源列表发送到AVOD终端,使得AVOD终端根据资源列表获取音频 - 视频资源。 本发明实现了平滑的多用户并发在线AVOD和降低网络系统的成本消耗。
    • 86. 发明授权
    • Quaternary ammonium salt compounds of spirocyclopiperazines, preparation methods and uses thereof
    • 螺环吡嗪的季铵盐化合物,其制备方法和用途
    • US09133195B2
    • 2015-09-15
    • US12305174
    • 2007-06-15
    • Runtao LiQi SunJia YeCaiqin YueXin WangZemei GeChangling LiTieming Cheng
    • Runtao LiQi SunJia YeCaiqin YueXin WangZemei GeChangling LiTieming Cheng
    • A61K31/55C07D471/10A61K31/438A61K31/5386C07D498/10C07D487/10C07D513/10C07D519/00
    • C07D471/10C07D487/10C07D498/10C07D513/10C07D519/00
    • Compounds represented by general formula (I), their stereoisomers, tautomers, derivatives, prodrugs or pharmaceutically acceptable salts, and their preparation methods or uses for the manufacture of a medicament of analgesics. In which R1 is selected from H, substituted or unsubstituted phenyl, or substituted or unsubstituted heteroaryl; A is bond, or saturated or unsaturated straight-chain or branched-chain hydrocarbon radical; R2, R3 are each independently hydrogen or methyl, which linked with any position of spirocyclo-structure; n and m are each independently integer between 0-2, do not represent 0 at the same time; B and D are each independently C1-C3 straight-chain or branched-chain alkylene; Y is selected from —CHR4—, O, S, —S(O)—, —SO2—, —NR4— and substituted or unsubstituted phenylene, in which R4 represents H, C1-C6 saturated or unsaturated alkyl, methyl or ethyl substituted by substituted or unsubstituted aryl or heteroaryl; and X− is pharmaceutical acceptable organic or inorganic anion. These compounds can be used as muscarine receptor (M-receptor) and/or nicotine acetylcholine receptor (N-receptor) agonist or antagonist. These compounds have good analgesic effect without side effect such as addiction.
    • 由通式(I)表示的化合物,其立体异构体,互变异构体,衍生物,前药或药学上可接受的盐,及其制备方法或用途,用于制备镇痛药物。 其中R1选自H,取代或未取代的苯基或取代或未取代的杂芳基; A是键或饱和或不饱和的直链或支链烃基; R2,R3各自独立地为氢或甲基,其与任何位置的螺环结构连接; n和m各自独立地为0-2之间的整数,不同时为0; B和D各自独立地为C1-C3直链或支链亚烷基; Y选自-CHR 4 - ,O,S,-S(O) - , - SO 2 - , - NR 4 - 和取代或未取代的亚苯基,其中R 4表示H,C 1 -C 6饱和或不饱和烷基,甲基或乙基取代 由取代或未取代的芳基或杂芳基取代; X-是药学上可接受的有机或无机阴离子。 这些化合物可用作毒蕈碱受体(M-受体)和/或尼古丁乙酰胆碱受体(N-受体)激动剂或拮抗剂。 这些化合物具有良好的止痛效果,无副作用,如成瘾。