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81. 发明申请

US20130197296A1 Removing Cells from an Organism 审中-公开
标题翻译：从有机体去除细胞
公开(公告)号：US20130197296A1
公开(公告)日：2013-08-01
申请号：US13740817
申请日：2013-01-14
申请人： Karl-Heinz Ott , Johannes Dapprich
发明人： Karl-Heinz Ott , Johannes Dapprich
IPC分类号： A61N2/00 , A61M3/00 , A61N2/06
CPC分类号： A61N2/004 , A61K9/0009 , A61K9/5094 , A61K9/5115 , A61K41/00 , A61K47/6941 , B82Y5/00
摘要： A minimally invasive method to eliminate circulating agents from an organism to prevent and treat diseases is disclosed. The method utilizes immunomagnetic methods to concentrate and localize disease-associated agents in a small region of the body. Subsequently, the complexes are removed from the body. Removal of disease-causing or disease-promoting agents (circulating tumor cells, bacteria, viruses and virus-infected cells, certain immune cells) would add a significant new option for intervention of disease progression and supplement other therapeutic options.
摘要翻译：公开了一种从生物体中消除循环剂以预防和治疗疾病的微创方法。该方法利用免疫磁性方法在身体的一小部分中集中和定位疾病相关药物。随后，将复合物从体内除去。去除致病或疾病促进剂（循环肿瘤细胞，细菌，病毒和病毒感染的细胞，某些免疫细胞）将为疾病进展的干预增加一个重要的新选择，并补充其他治疗选择。

82. 发明申请

US20060156427A1 Structure-based designed herbicide resistant products 审中-公开
公开(公告)号：US20060156427A1
公开(公告)日：2006-07-13
申请号：US11033687
申请日：2005-01-12
申请人： Genichi Kakefuda , Karl-Heinz Ott , Jae-Gyu Kwagh , Gerald Stockton
发明人： Genichi Kakefuda , Karl-Heinz Ott , Jae-Gyu Kwagh , Gerald Stockton
IPC分类号： C12N15/82 , G06G7/48 , G06G7/58 , A01H1/00
CPC分类号： C12N9/88 , C12N15/8278 , G16B15/00
摘要： Disclosed herein are structure-based modelling methods for the preparation of acetohydroxy acid synthase (AHAS) variants, including those that exhibit selectively increased resistance to herbicides such as imidazoline herbicides and AHAS inhibiting herbicides. The invention encompasses isolated DNAs encoding such variants, vectors that include the DNAs, and methods for producing the variant polypeptides and herbicide resistant plants containing specific AHAS gene mutations. Methods for weed control in crops are also provided.

83. 发明授权

US06855533B2 Structure-based designed herbicide resistant products 失效
标题翻译：基于结构设计的除草剂抗性产品
公开(公告)号：US06855533B2
公开(公告)日：2005-02-15
申请号：US10407339
申请日：2003-04-04
申请人： Genichi Kakefuda , Karl-Heinz Ott , Jae-Gyu Kwagh , Gerald W. Stockton
发明人： Genichi Kakefuda , Karl-Heinz Ott , Jae-Gyu Kwagh , Gerald W. Stockton
IPC分类号： A01H5/00 , C07K14/415 , C12N1/15 , C12N1/21 , C12N5/10 , C12N9/88 , C12N15/09 , C12N15/82 , C12P21/02 , C12R1/19
CPC分类号： C12N9/88 , C12N15/8278 , G06F19/16
摘要： Disclosed herein are structure-based modelling methods for the preparation of acetohydroxy acid synthase (AHAS) variants, including those that exhibit selectively increased resistance to herbicides such as imidazoline herbicides and AHAS inhibiting herbicides. The invention encompasses isolated DNAs encoding such variants, vectors that include the DNAs, and methods for producing the variant polypeptides and herbicide resistant plants containing specific AHAS gene mutations. Methods for weed control in crops are also provided.
摘要翻译：本文公开了用于制备乙酰羟酸合酶（AHAS）变体的基于结构的建模方法，包括对除草剂如咪唑啉除草剂和AHAS抑制性除草剂显示选择性增加的抗性的那些。本发明包括编码这种变体的分离的DNA，包括DNA的载体，以及用于产生含有特异性AHAS基因突变的变体多肽和除草剂抗性植物的方法。还提供了作物杂草防治方法。

84. 发明授权

US06321774B1 Control valve for cryogenic use 失效
标题翻译：低温控制阀
公开(公告)号：US06321774B1
公开(公告)日：2001-11-27
申请号：US09483609
申请日：2000-01-14
申请人： Karl-Heinz Ott
发明人： Karl-Heinz Ott
IPC分类号： F16K326
CPC分类号： F16K31/52 , F02K9/58 , F16K1/12 , F16K31/047 , F16K31/52433 , F16K31/54 , G05D16/202 , Y10T137/3367 , Y10T137/86734
摘要： A motor-driven control valve for cryogenically liquified rocket propellant comprises a valve casing with a co-axial inlet port and outlet port, a slidable regulating sleeve, an electric motor, a gear, a drive chamber within the casing, and a drive transmission in the drive chamber. The regulating sleeve is centrally arranged and slidably mounted and sealed in the valve casing and the drive chamber. Flow slots are circumferentially distributed around the regulating sleeve. The externally mounted motor and gear control the position of the regulating sleeve through the drive transmission. Sliding adjustment of the position of the sleeve regulates the exposed cross-section of the flow slots, thereby also regulating the open and closed switching of the control valve. The regulating sleeve is the only moving part exposed to the flowing liquid, and the liquid pressure and flow forces act only radially on the axially slidable sleeve, so that the hydraulic forces do not influence the driving force required for opening and closing the valve.
摘要翻译：用于低温液化火箭推进剂的电动控制阀包括具有同轴入口和出口的阀壳，可滑动调节套，电动马达，齿轮，壳体内的驱动室，以及驱动传动装置驱动室。调节套筒集中布置并可滑动地安装并密封在阀壳体和驱动室中。流动槽围绕调节套筒周向分布。外部安装的电机和齿轮通过驱动传动装置控制调节套筒的位置。套筒的位置的滑动调节调节流槽的暴露横截面，从而也调节控制阀的打开和闭合切换。调节套筒是仅暴露于流动液体的唯一移动部件，液体压力和流动力仅在径向上作用在可轴向滑动的套筒上，使得液压力不影响打开和关闭阀门所需的驱动力。

85. 发明授权

US5225465A Process for working up stabilized ABS polymers with recovery of unreacted monomers 失效
标题翻译：加工稳定的ABS聚合物与回收单体的工艺
公开(公告)号：US5225465A
公开(公告)日：1993-07-06
申请号：US864302
申请日：1992-04-06
申请人： Herbert Eichenauer , Ulrich Jansen , Ralph Ostarek , Otto Koch , Karl-Heinz Ott
发明人： Herbert Eichenauer , Ulrich Jansen , Ralph Ostarek , Otto Koch , Karl-Heinz Ott
IPC分类号： C08F6/16 , C08F6/00 , C08F6/06 , C08F279/00 , C08F279/04 , C08J11/02 , C08K5/13 , C08K5/36 , C08L55/00 , C08L55/02
CPC分类号： C08F6/003 , C08F279/04
摘要： A process for processing polymers of the ABS type present in emulsion form and effectively stabilized against oxidative attack with optionally continuous recovery and direct reuse of untreated monomers, wherein a combination of at least one phenolic antioxidant having a molecular weight above 300 without ester groups in the molecule and at least one sulfur-containing co-stabilizer having a molecular weight above 500 without ester groups in the molecule is added to the ABS polymer emulsion for stabilization against oxidative degradation.
摘要翻译：一种用于处理以乳液形式存在的ABS型聚合物的方法，并有效稳定的抗氧化攻击，可任选地连续回收和直接再利用未处理的单体，其中至少一种分子量大于300的酚类抗氧化剂在没有酯基的组合中分子和至少一种分子量大于500的含硫共聚稳定剂，而不分子中的酯基被加入到ABS聚合物乳液中，以防止氧化降解。

86. 发明授权

US5112910A Mixtures of thermoplastic polymers in powder form 失效
标题翻译：粉末形式的热塑性聚合物的混合物
公开(公告)号：US5112910A
公开(公告)日：1992-05-12
申请号：US743678
申请日：1991-08-12
申请人： Karl-Erwin Piejko , Christian Lindner , Ralph Ostarek , Hans-Eberhard Braese , Karl-Heinz Ott
发明人： Karl-Erwin Piejko , Christian Lindner , Ralph Ostarek , Hans-Eberhard Braese , Karl-Heinz Ott
IPC分类号： C08J3/00 , C08L21/00 , C08L25/12 , C08L33/06 , C08L33/12 , C08L51/04
CPC分类号： C08L33/06 , C08J3/005 , C08L21/00 , C08L25/12 , C08L33/12 , C08L51/04
摘要： Process for the preparation of mixtures of thermoplastic polymers in powder form from aqueous emulsions ofa) particulate, partly crosslinked rubber-like copolymers of a C.sub.2 -C.sub.8 -alkyl acrylate and/or butadiene with (based on the copolymer) up to 40 wt. % acrylonitrile, styrene or C.sub.1 -C.sub.4 -alkyl methacrylate,b) a thermoplastic resin, and if appropriatec) a rubber-rich graft polymer of styrene, .alpha.-methylstyrene, acrylonitrile, methyl methacrylate and/or alkyl acrylate on a diene or alkyl acrylate rubber having a rubber content of 50 to 95 wt. %,wherein aqueous emulsions of a) and b) and if appropriate c) having polymer contents of 15 to 50 wt. % are mixed with a coagulate solution simultaneously, but in separate streams, continuously or semi-continuously at 20.degree. to 100.degree. C., the polymers a) and b) and if appropriate c) being coagulated, the streams are combined and the polymer mixture is then separated off.
摘要翻译：制备粉末形式的热塑性聚合物的混合物的方法，该方法由以下混合物的水性乳液制备：a）丙烯酸C 2 -C 8烷基酯和/或丁二烯与（基于共聚物）的至少40重量％的颗粒部分交联的橡胶状共聚物。丙烯腈，苯乙烯或甲基丙烯酸C 1 -C 4烷基酯，b）热塑性树脂，如果合适，c）在二烯或烷基上的苯乙烯，α-甲基苯乙烯，丙烯腈，甲基丙烯酸甲酯和/或丙烯酸烷基酯的富含橡胶的接枝聚合物丙烯酸酯橡胶，其橡胶含量为50〜95重量％％，其中a）和b）和如果合适的水性乳液c）具有15至50重量％的聚合物含量。％与凝固溶液同时混合，但在单独的流中，在20℃至100℃连续或半连续，聚合物a）和b），如果合适，c）凝结，将流合并，聚合物混合物然后分离出来。

87. 发明授权

US5028349A Moulding compositions having uniform particle size and improved thermal stability 失效
标题翻译：成型组合物具有均匀的粒度和改善的热稳定性
公开(公告)号：US5028349A
公开(公告)日：1991-07-02
申请号：US175053
申请日：1988-03-30
申请人： Herbert Eichenauer , Alfred Pischtschan , Karl-Heinz Ott
发明人： Herbert Eichenauer , Alfred Pischtschan , Karl-Heinz Ott
IPC分类号： C08L51/04 , C08C1/00 , C08F8/34 , C08F279/02 , C08J3/00 , C08J3/16 , C08L7/00 , C08L21/00 , C08L33/00 , C08L33/02 , C08L51/00 , C08L51/02 , C08L55/00 , C08L55/02 , C08L57/00
CPC分类号： C08J3/005 , C08F279/02 , C08F279/04
摘要： Elastic-thermoplastic or thermoplastic powder-form moulding compositions having uniform particles size and improved thermal stability and processes for their manufacture.
摘要翻译：弹性热塑性或热塑性粉末成型组合物具有均匀的粒度和改善的热稳定性及其制造方法。

88. 发明授权

US4968750A Block copolymers containing polysiloxane segments 失效
标题翻译：含有聚硅氧烷链段的嵌段共聚物
公开(公告)号：US4968750A
公开(公告)日：1990-11-06
申请号：US427935
申请日：1989-10-25
申请人： Herbert Eichenauer , Christian Lindner , Karl-Heinz Ott
发明人： Herbert Eichenauer , Christian Lindner , Karl-Heinz Ott
IPC分类号： C08G77/442
CPC分类号： C08G77/442
摘要： Block copolymers composed of recurrent structural units belonging to the series comprising polysiloxanes and recurring structural units belonging to the series comprising homopolymers, copolymers or terpolymers of vinyl-aromatic compounds and acrylic monomers of mixtures thereof.
摘要翻译：由属于包含聚硅氧烷的系列的复发结构单元和属于该系列的重复结构单元组成的嵌段共聚物包括乙烯基芳族化合物的均聚物，共聚物或三元共聚物和其混合物的丙烯酸单体。

89. 发明授权

US4885337A Process for the preparation of thermoplastic moulding compositions 失效
标题翻译：制备热塑性模塑组合物的方法
公开(公告)号：US4885337A
公开(公告)日：1989-12-05
申请号：US69967
申请日：1987-07-06
申请人： Herbert Eichenauer , Alfred Pischtschan , Karl-Heinz Ott
发明人： Herbert Eichenauer , Alfred Pischtschan , Karl-Heinz Ott
IPC分类号： C08F279/04 , C08F2/22 , C08F279/00 , C08F279/02 , C08L25/12 , C08L51/00 , C08L51/04 , C08L55/00 , C08L55/02
CPC分类号： C08L25/12 , C08F279/02 , C08L51/04
摘要： Process for the preparation of a thermoplastic moulding composition of 10 to 65% by weight of at least one graft polymer which is obtainable by emulsion polymerization of styrene and acrylonitrile in a weight ratio of 90:10 to 50:50, it being possible for all or some of the styrene to be replaced by .alpha.-methylstyrene or methyl methacrylate, in the presence of at least one rubber base, and the weight ratio of monomers employed to rubber polymer employed being 20:80 to 70:30, and 90 to 35% by weight of a copolymer of styrene and acrylonitrile in a weight ratio of 90:10 to 50:50, it being possible for all or some of the styrene to be replaced by .alpha.-methylstyrene or methyl methacrylate, wherein, to prepare the graft polymer, the grafting monomers and 0.05 to 1.00 part by weight (per 100 parts by weight of grafting monomer) of a mercaptan are added stepwise to the latex of the rubber base over a period of time, the part amount of the monomer added in each time interval .DELTA.t.sub.n+1 being 0.30 to 0.95 times the amount of monomer added in the preceding time interval .DELTA.t.sub.n at least in the first half of the period of time, and the total period of time comprising n time intervals where n=3 to 30, and each time interval .DELTA.t being 5 to 100 minutes long.
摘要翻译：用于制备10至65重量％的至少一种接枝聚合物的热塑性模塑组合物的方法，所述接枝聚合物可以通过苯乙烯和丙烯腈的重量比为90:10至50:50的乳液聚合而获得，所有这些都可能或由至少一个橡胶基团存在下由α-甲基苯乙烯或甲基丙烯酸甲酯代替的一些苯乙烯，并且所用单体与橡胶聚合物的重量比为20:80至70:30和90至35 重量比为90:10至50:50的苯乙烯和丙烯腈的共聚物的重量比，可以用α-甲基苯乙烯或甲基丙烯酸甲酯代替全部或一些苯乙烯，其中制备接枝物聚合物，接枝单体和0.05至1.00重量份（每100重量份接枝单体）硫醇在一段时间内逐步添加到橡胶基料的胶乳上，每次加入单体的部分量时间间隔DELTA tn + 1 bei ng至少在上述时间段的前半部分中，在上述时间间隔DELTA tn中添加的单体量的0.30〜0.95倍，n = 3〜30的n个时间间隔的总时间，以及每个时间间隔长达5到100分钟。

90. 发明授权

US4772668A Sulphur-containing graft products 失效
标题翻译：含硫移植产品
公开(公告)号：US4772668A
公开(公告)日：1988-09-20
申请号：US827390
申请日：1986-02-10
申请人： Herbert Eichenauer , Alfred Pischtschan , Karl-Heinz Ott
发明人： Herbert Eichenauer , Alfred Pischtschan , Karl-Heinz Ott
IPC分类号： C08L51/00 , C08F2/38 , C08F279/00 , C08F279/02 , C08F291/02 , C08L7/00 , C08L21/00 , C08L33/00 , C08L33/02 , C08L51/02 , C08L51/04 , C08L55/00 , C08L55/02
CPC分类号： C08F279/02 , C08F291/02
摘要： Sulphur-containing elastic-thermoplastic graft products of styrene, .alpha.-methyl styrene, p-methyl styrene, vinyl toluene, acrylonitrile or methyl methacrylate or mixtures thereof on a particle-like rubber with an average particle diameter (d.sub.50) of from 0.05 to 20.0 .mu.m and a glass temperature .ltoreq.10.degree. C. with a total rubber content of from 1 to 80% by weight, whereby the graft products have a sulphur content of from 1.15 to 3.95% by weight and the thermoplast proportion of the polymerized monomers on the particle-like rubber has a limiting viscosity of from 2 to 15 ml/g (measured in dimethyl formamide at 25.degree. C.) and in which at least 90% by weight of the incorporated sulphur is present as a constituent of terminal C1-18-thioalkyl groups.
摘要翻译：苯乙烯，α-甲基苯乙烯，对甲基苯乙烯，乙烯基甲苯，丙烯腈或甲基丙烯酸甲酯或其混合物在平均粒径（d50）为0.05至20.0的颗粒状橡胶上的含硫弹性 - 热塑性接枝产物微米，玻璃温度为10℃，总橡胶含量为1〜80重量％，由此接枝产物的硫含量为1.15〜3.95重量％，聚合物的热塑性比例颗粒状橡胶上的单体的特性粘度为2至15ml / g（在25℃的二甲基甲酰胺中测量），并且其中至少90重量％的引入的硫作为末端的成分存在 C 1-18 - 硫烷基。

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