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81. 发明申请

US20110077385A1 Protein arrays 审中-公开
标题翻译：蛋白质阵列
公开(公告)号：US20110077385A1
公开(公告)日：2011-03-31
申请号：US12590440
申请日：2009-11-05
申请人： Peter G. Schultz , Lei Wang
发明人： Peter G. Schultz , Lei Wang
IPC分类号： C07K17/00
CPC分类号： C07K17/06 , C07K1/047 , C07K1/1077 , Y10S435/97 , Y10S530/811
摘要： The invention provides proteins attached to solid supports, and methods of preparing such solid support-bound proteins are provided. The proteins are attached to solid supports by means of an unnatural amino acid incorporated into the protein, which unnatural amino acid includes a reactive group that can react with a second reactive group that is attached to a solid support.
摘要翻译：本发明提供了连接到固体支持物上的蛋白质，并且提供了制备这种固体支持结合蛋白质的方法。蛋白质通过引入到蛋白质中的非天然氨基酸连接到固体支持物上，该非天然氨基酸包括可与连接到固体支持物上的第二反应性基团反应的反应性基团。

82. 发明授权

US07907528B2 Managing power consumption in a NIC team 有权
标题翻译：管理NIC小组的功耗
公开(公告)号：US07907528B2
公开(公告)日：2011-03-15
申请号：US11554015
申请日：2006-10-28
申请人： Wei Liu , Lei Wang , Jianwen Yin
发明人： Wei Liu , Lei Wang , Jianwen Yin
IPC分类号： H04J1/16
CPC分类号： H04L47/10 , H04L12/12 , H04L47/125 , Y02D50/20 , Y02D50/40 , Y02D50/42
摘要： The present disclosure provides an information handling system which includes a team of network interface controllers (NIC), each controller operable to receive network traffic load. The system also includes logic configured to direct the network traffic load to at least one NIC in the team based on the network traffic load. The present disclosure may result in overall power savings for system.
摘要翻译：本公开提供了一种信息处理系统，其包括一组网络接口控制器（NIC），每个控制器可操作以接收网络业务负载。该系统还包括配置为基于网络流量负载将网络流量负载引导到团队中的至少一个NIC的逻辑。本公开可以导致系统的总体功率节省。

83. 发明申请

US20110051669A1 METHOD AND APPARATUS FOR MEDIUM ACCESS CONTROL IN-ORDER DELIVERY 有权
标题翻译：用于中型访问控制订单交付的方法和装置
公开(公告)号：US20110051669A1
公开(公告)日：2011-03-03
申请号：US12872162
申请日：2010-08-31
申请人： Lei Wang , Eldad M. Zeira
发明人： Lei Wang , Eldad M. Zeira
IPC分类号： H04W4/00
CPC分类号： H04L47/624 , H04L1/1829 , H04L47/34 , H04L69/324 , H04W28/04 , H04W72/044
摘要： Method and apparatus for MAC in-order delivery are disclosed. The MAC in-order delivery may be activated per-connection and may be negotiated at connection setup. The MAC in-order delivery either for non-ARQ connections or ARQ connections may be performed by using HARQ packet ordering information. Alternatively, the MAC in-order delivery may be performed using a sequence number (SN) field at the MAC PDU level or using an SN field at the MAC SDU level. For a connection that has MAC in-order delivery disabled, the MAC PDU may not include an SN field, and an SN field may be included in a MAC extended header or a MAC sub-header when needed.
摘要翻译：公开了MAC顺序传送的方法和装置。可以按连接激活MAC按顺序传送，并且可以在连接建立时协商。可以通过使用HARQ分组排序信息来执行用于非ARQ连接或ARQ连接的MAC按顺序传送。或者，可以使用MAC PDU级别的序列号（SN）字段或者使用MAC SDU级别的SN字段来执行MAC按顺序传送。对于禁止MAC按顺序传送的连接，MAC PDU可以不包括SN字段，并且当需要时可以将SN字段包括在MAC扩展报头或MAC子报头中。

84. 发明授权

US07834159B2 Glycoprotein synthesis 失效
标题翻译：糖蛋白合成
公开(公告)号：US07834159B2
公开(公告)日：2010-11-16
申请号：US11580203
申请日：2006-10-11
申请人： Peter G. Schultz , Lei Wang , Zhiwen Zhang
发明人： Peter G. Schultz , Lei Wang , Zhiwen Zhang
IPC分类号： C07K14/00 , A61K38/00
CPC分类号： C12P21/005
摘要： Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.
摘要翻译：提供在体外和体内制备糖蛋白的方法。一种方法包括将非天然氨基酸掺入蛋白质并将一个或多个糖部分连接到非天然氨基酸上。另一种方法包括将包含糖部分的非天然氨基酸掺入蛋白质中。通过两种方法制备的蛋白质可以用额外的糖进一步修饰。

85. 发明授权

US07825226B2 Glycoprotein synthesis 失效
公开(公告)号：US07825226B2
公开(公告)日：2010-11-02
申请号：US11978232
申请日：2007-10-26
申请人： Peter G. Schultz , Lei Wang , Zhiwen Zhang
发明人： Peter G. Schultz , Lei Wang , Zhiwen Zhang
IPC分类号： C07K14/00 , A61K38/16
CPC分类号： C12P21/005
摘要： Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

86. 发明申请

US20100077409A1 SYSTEM INTEGRATED TEAMING 有权
标题翻译：系统集成团队
公开(公告)号：US20100077409A1
公开(公告)日：2010-03-25
申请号：US12237576
申请日：2008-09-25
申请人： Hendrich M. Hernandez , Lei Wang
发明人： Hendrich M. Hernandez , Lei Wang
IPC分类号： G06F13/00
CPC分类号： G06F13/102
摘要： A network teaming system includes one or more subsystems to provide a hardware system integrated teaming assistant (SITA hardware), provide a software system integrated teaming assistant (SITA software) operable with the SITA hardware and provide a feature checking and enablement system (FCE), wherein the FCE determines one or more networking features for members of a team coupled together on a network, and wherein the SITA hardware in combination with the SITA software perform a networking feature for a member of the team who does not have the capability to perform the networking feature.
摘要翻译：网络组合系统包括一个或多个子系统，以提供硬件系统集成组合助手（SITA硬件），提供可与SITA硬件一起使用的软件系统集成组合助手（SITA软件），并提供功能检查和启用系统（FCE）其中所述FCE为在网络上耦合在一起的团队的成员确定一个或多个联网特征，并且其中所述SITA硬件与所述SITA软件结合执行所述团队成员的网络特征，所述团队的成员不具有执行网络功能。

87. 发明授权

US07648986B2 Substituted thieno[3,2-D]pyrimidines as Rho kinase inhibitors 失效
标题翻译：取代噻吩并[3,2-D]嘧啶作为Rho激酶抑制剂
公开(公告)号：US07648986B2
公开(公告)日：2010-01-19
申请号：US11733045
申请日：2007-04-09
申请人： Dhanapalan Nagarathnam , Uday Khire , Davoud Asgari , Jianxing Shao , Xiao-Gao Liu , Chunguang Wang , Barry Hart , Olaf Weber , Mark Lynch , Lei Zhang , Lei Wang
发明人： Dhanapalan Nagarathnam , Uday Khire , Davoud Asgari , Jianxing Shao , Xiao-Gao Liu , Chunguang Wang , Barry Hart , Olaf Weber , Mark Lynch , Lei Zhang , Lei Wang
IPC分类号： C07D495/04 , C07D251/16 , C07D413/10 , A61K31/519 , A61K31/5377 , A61K31/53 , A61K31/497 , A61K31/496 , A61K31/498 , A61P9/12 , A61P9/10 , A61P35/04 , A61P11/06 , C07D401/12 , C07D401/14
CPC分类号： C07D471/04 , C07D491/04 , C07D495/04
摘要： Disclosed are compounds and derivatives thereof their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
摘要翻译：公开了其化合物及其衍生物的合成及其作为Rho-激酶抑制剂的用途。本发明的这些化合物可用于抑制肿瘤生长，治疗勃起功能障碍，以及治疗由Rho-激酶（例如冠心病）介导的其它适应症。

88. 发明授权

US07641431B2 Fastening device for heat sink 失效
标题翻译：散热器紧固装置
公开(公告)号：US07641431B2
公开(公告)日：2010-01-05
申请号：US11839470
申请日：2007-08-15
申请人： Jun Luo , Lei Wang , Cui-Jun Lu , Chin-Lung Chen
发明人： Jun Luo , Lei Wang , Cui-Jun Lu , Chin-Lung Chen
IPC分类号： F16B21/18
CPC分类号： F16B35/04 , F16B5/0208
摘要： A fastening device for a heat sink includes a one-piece shaft. The shaft includes a head at one end thereof, an engaging section at an opposite end thereof, a connecting section between the head and the engaging section, and a tray extending above the engaging section. A spring surrounds the connecting section between the head and the tray of the shaft. A gasket engages with the connecting section of the shaft and is retained between the spring and the tray of the shaft. In this way the shaft, the spring and the gasket are assembled. The gasket extends a downward, annular sidewall for engaging in the heat sink, by which the fastening device can be stably fixed to the heat sink. A back plate extends a nut toward the shaft for engaging with the engaging section of the shaft.
摘要翻译：用于散热器的紧固装置包括一体式轴。轴在其一端包括头部，在其相对端部处的接合部分，头部和接合部分之间的连接部分以及在接合部分上方延伸的托盘。弹簧围绕头部和轴的托盘之间的连接部分。垫圈与轴的连接部分接合并保持在弹簧和轴托盘之间。以这种方式组装轴，弹簧和垫圈。垫圈向下延伸的环形侧壁，用于接合散热器，紧固装置可以被固定到散热器。后板将螺母朝向轴延伸以与轴的接合部分接合。

89. 发明申请

US20090318560A1 FORMULATIONS FOR CATHEPSIN K INHIBITORS 审中-公开
标题翻译：卡贝汀K抑制剂的配方
公开(公告)号：US20090318560A1
公开(公告)日：2009-12-24
申请号：US12527876
申请日：2008-02-22
申请人： Wayne Parent , Mahtab Afaghi , David Breslin , Mireille Granger , Lei Wang , Jeff Zimmerman
发明人： Wayne Parent , Mahtab Afaghi , David Breslin , Mireille Granger , Lei Wang , Jeff Zimmerman
IPC分类号： A61K31/165
CPC分类号： A61K31/277 , A61K9/0019 , A61K9/2013 , A61K9/2018 , A61K9/2054 , A61K9/4858 , A61K9/4866 , A61K31/165 , C07D209/42
摘要： The instant invention relates to pharmaceutical compositions comprising cathepsin K inhibitors as the active ingredient with excipients which include binders, diluents, lubricants, and disintegrants. Also disclosed are processes for making said pharmaceutical compositions for oral and intravenous delivery.
摘要翻译：本发明涉及包含组织蛋白酶K抑制剂作为活性成分的包含粘合剂，稀释剂，润滑剂和崩解剂的赋形剂的药物组合物。还公开了制备用于口服和静脉内递送的所述药物组合物的方法。

90. 发明申请

US20090293069A1 METHOD AND APPARATUS FOR SYNCHRONIZING DATA BETWEEN TERMINALS 审中-公开
标题翻译：用于同步终端之间的数据的方法和装置
公开(公告)号：US20090293069A1
公开(公告)日：2009-11-26
申请号：US12511764
申请日：2009-07-29
申请人： Jian Yang , Lei Wang , Guoqiao Chen
发明人： Jian Yang , Lei Wang , Guoqiao Chen
IPC分类号： G06F9/44
CPC分类号： H04L67/1095 , G06F8/65 , G06F16/27 , H04L67/02
摘要： A method and apparatus for synchronizing data between terminals are disclosed. The method includes these steps: a user sends data to a server through a terminal that corresponds to a certain access mode; the server sends a notification message to terminals that correspond to other access modes of the user, and the terminals that correspond to other access modes obtain the data through the server. The apparatus includes a data receiving module, a notification message sending module, and a data sending module. The present invention may enable terminals that correspond to other access modes of the user to know the data status of the server and perform data synchronization in time after the user sends data to the server through a terminal that corresponds to a certain access mode.
摘要翻译：公开了一种在终端之间同步数据的方法和装置。该方法包括以下步骤：用户通过对应于特定接入模式的终端向服务器发送数据; 服务器向对应于用户的其他接入模式的终端发送通知消息，对应于其他接入模式的终端通过服务器获取数据。该装置包括数据接收模块，通知消息发送模块和数据发送模块。本发明可以使得与用户的其他访问模式相对应的终端能够在用户通过对应于特定访问模式的终端向服务器发送数据之后，及时地知道服务器的数据状态并进行数据同步。

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