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    • 84. 发明授权
    • Vagus nerve neurostimulator with multiple patient-selectable modes for treating chronic cardiac dysfunction
    • 迷走神经神经刺激器具有多种患者可选择的治疗慢性心脏功能障碍的模式
    • US08571654B2
    • 2013-10-29
    • US13352244
    • 2012-01-17
    • Imad LibbusBadri AmurthurBruce H. KenKnight
    • Imad LibbusBadri AmurthurBruce H. KenKnight
    • A61N1/365
    • A61N1/0551A61N1/36053A61N1/36114A61N1/3727
    • A vagus nerve neurostimulator system with multiple patient-selectable modes for treating chronic cardiac dysfunction is provided. An implantable neurostimulator includes a pulse generator coupled to a therapy lead terminated by a pair of helical electrodes positioned over a cervical vagus nerve. The pulse generator is configured to deliver through the helical electrodes continuously-cycling, intermittent and periodic electrical stimulation that is parametrically defined to bi-directionally propagate through nerve fibers in the cervical vagus nerve. The implantable neurostimulator includes a magnetic switch configured to switch the pulse generator between a plurality of operating modes that are each separately selectable in response to a unique and remotely-applied magnetic signal. An external controller includes patient-actuatable controls configured to enable selection of one of the operating modes of the pulse generator. The external controller includes an electromagnetic transmitter configured to output the magnetic signal uniquely associated with the operating mode as selected with the controls.
    • 提供了一种具有多种患者可选择的用于治疗慢性心脏功能障碍的模式的迷走神经神经刺激器系统。 可植入的神经刺激器包括一个脉冲发生器,该脉冲发生器耦合到由位于颈部迷走神经上的一对螺旋电极终止的治疗引线。 脉冲发生器被配置为通过螺旋电极连续循环,间歇和周期性电刺激传递,其被参数限定以通过颈部迷走神经中的神经纤维双向传播。 可植入神经刺激器包括磁开关,其被配置为在多个操作模式之间切换脉冲发生器,所述多个操作模式可以响应于独特的和远程施加的磁信号而分别可选择。 外部控制器包括被配置为能够选择脉冲发生器的一个操作模式的患者致动控制。 外部控制器包括电磁发射机,其被配置为输出与通过控制选择的操作模式唯一相关联的磁信号。