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81. 发明申请

US20100171021A1 HOLDER SYSTEMS FOR MOBILE DEVICES 有权
标题翻译：手机装置系统
公开(公告)号：US20100171021A1
公开(公告)日：2010-07-08
申请号：US12683428
申请日：2010-01-06
申请人： Mark Smith
发明人： Mark Smith
IPC分类号： F16M13/02 , F16M13/00 , A45F5/00 , B65H75/40
CPC分类号： F16M13/04 , A45C13/30 , A45C2011/001 , A45F5/00 , A45F5/004 , A45F5/02 , A45F2003/003 , A45F2200/0516 , A45F2200/055 , B65H75/4418 , B65H75/446 , B65H2701/34 , F16M11/041 , F16M11/046 , F16M11/18 , F16M13/00
摘要： A holder system for mobile devices includes a generally rectangular holder base and a holder configured to secure the mobile device therein. The holder may be removably attachable to the holder base. A retractor mechanism may be attached to the holder base. The holder base includes a pair of spaced cord ports, each cord port receiving a line part of a retractable cord that is engaged to the retractor mechanism.
摘要翻译：用于移动设备的固定器系统包括大致矩形的保持器基座和配置成将移动设备固定在其中的保持器。保持器可以可移除地附接到保持器基座。牵引器机构可以附接到保持器基座。保持器基座包括一对间隔开的线端口，每个线端口接收与牵开器机构接合的可伸缩线的线部分。

82. 发明申请

US20090325172A1 Modified nucleotides 有权
标题翻译：修饰的核苷酸
公开(公告)号：US20090325172A1
公开(公告)日：2009-12-31
申请号：US12455397
申请日：2009-06-01
申请人： John Milton , Xiaolin Wu , Mark Smith , Joseph Brennan , Colin Barnes , Xiaohai Liu , Silke Ruediger
发明人： John Milton , Xiaolin Wu , Mark Smith , Joseph Brennan , Colin Barnes , Xiaohai Liu , Silke Ruediger
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6869 , C07H1/00 , C07H19/06 , C07H19/10 , C07H19/14 , C07H19/16 , C07H19/20 , C07H21/00 , C12Q2525/186 , C12Q2535/113 , Y02P20/55 , C12Q2525/197
摘要： The invention provides modified nucleotide or nucleoside molecule comprising a purine or pyrimidine base and a ribose or deoxyribose sugar moiety having a removable 3′-OH blocking group covalently attached thereto, such that the 3′ carbon atom has attached a group of the structure —O-Z wherein Z is any of —C(R′)2-O—R″, —C(R′)2-N(R″)2, —C(R′)2-N(H)R″, —C(R′)2-S—R″ and —C(R′)2-F, wherein each R″ is or is part of a removable protecting group; each R′ is independently a hydrogen atom, an alkyl, substituted alkyl, arylalkyl, alkenyl, alkynyl, aryl, heteroaryl, heterocyclic, acyl, cyano, alkoxy, aryloxy, heteroaryloxy or amido group, or a detectable label attached through a linking group; or (R′)2 represents an alkylidene group of formula ═C(R′″)2 wherein each R′″ may be the same or different and is selected from the group comprising hydrogen and halogen atoms and alkyl groups; and wherein said molecule may be reacted to yield an intermediate in which each R″ is exchanged for H or, where Z is —C(R′)2-F, the F is exchanged for OH, SH or NH2, preferably OH, which intermediate dissociates under aqueous conditions to afford a molecule with a free 3′OH; with the proviso that where Z is —C(R′)2-S—R″, both R′ groups are not H.
摘要翻译：本发明提供了修饰的核苷酸或核苷分子，其包含嘌呤或嘧啶碱基和核糖或脱氧核糖糖部分，其具有共价连接到其上的可移除的3'-OH封闭基团，使得3'碳原子连接有一组结构-OZ 其中Z是-C（R'）2 -O-R“，-C（R'）2 -N（R”）2，-C（R'）2 -N（H）R“ ，-C（R'）2 -S-R“和-C（R'）2 -F，其中每个R”或是可除去的保护基团的一部分; 每个R'独立地是氢原子，烷基，取代的烷基，芳基烷基，烯基，炔基，芳基，杂芳基，杂环，酰基，氰基，烷氧基，芳氧基，杂芳氧基或酰氨基，或通过连接基团连接的可检测标记; 或（R'）2表示式-C（R“'）2的亚烷基，其中每个R”可以相同或不同，并且选自氢和卤素原子和烷基; 并且其中所述分子可以反应以产生其中每个R“被交换为H的中间体，或者其中Z是-C（R'）2-F，F被交换成OH，SH或NH 2，优选OH，该中间体在水性条件下解离以得到具有游离3'OH的分子; 条件是其中Z是-C（R'）2 -S-R“，两个R'基团都不是H.

83. 发明申请

US20080287873A1 METHOD AND APPARATUS FOR CONTROLLING OPERATION OF A SYRINGE 审中-公开
标题翻译：一种用于控制SYRINGE操作的方法和装置
公开(公告)号：US20080287873A1
公开(公告)日：2008-11-20
申请号：US12102234
申请日：2008-04-14
申请人： Aldo LIBERATORE , Mark Smith
发明人： Aldo LIBERATORE , Mark Smith
IPC分类号： A61M5/20
CPC分类号： A61M5/1456 , A61M5/16827 , A61M5/172
摘要： A system is provided for controlling operation of a syringe. The system comprises a controller having an interface and at least one input mechanism; and a syringe gun communicably connected to the controller. The syringe gun comprises an elongated body with an open faced barrel cradle and open faced plunger bay for holding a syringe in the body, a plunger cradle moveable within the plunger bay for operating on a plunger of the syringe, and an actuating device for moving the plunger cradle according to a control signal. The controller generates the control signal for controlling the syringe gun.
摘要翻译：提供一种用于控制注射器的操作的系统。该系统包括具有接口和至少一个输入机构的控制器; 以及可连接到控制器的注射器枪。注射器枪包括具有敞开的桶支架的细长主体和用于将注射器保持在主体中的开口的柱塞间隔;活塞支架，其可在柱塞间隔中移动，用于在注射器的柱塞上操作;以及致动装置，活塞支架根据控制信号。控制器产生用于控制注射枪的控制信号。

84. 发明授权

US07438222B2 Card reading arrangement including robotic card handling responsive to card sensing 失效
标题翻译：读卡装置，包括响应于卡感测的机器人卡处理
公开(公告)号：US07438222B2
公开(公告)日：2008-10-21
申请号：US11998941
申请日：2007-12-03
申请人： Patrick C. Green , Mark Smith , Natarajan Ramachandran , Daniel J. Delaney , David A. Barker , Franklin M. Theriault , Elizabeth Herrera , Jeffrey A. Hill , Mark Douglas
发明人： Patrick C. Green , Mark Smith , Natarajan Ramachandran , Daniel J. Delaney , David A. Barker , Franklin M. Theriault , Elizabeth Herrera , Jeffrey A. Hill , Mark Douglas
IPC分类号： G06F17/00
CPC分类号： G06Q40/00 , G06Q20/1085 , G07F19/20 , G07F19/205 , G07F19/206
摘要： A card reader arrangement includes a robotic card handling device to enable reading of a user card during a card-based transaction. A card sensing device is located adjacent a card slot remotely located from a card reader. Responsive to the card sensing device sensing an inserted card, the robotic card handling device operates to grip the card in the slot and move it to a reading position in the card reader. The card reader can also operate in conjunction with a biometric reading device in a process of determining whether the card user is authorized to use the card. The robotic card handling device can also be operated to grip other transaction items.
摘要翻译：读卡器装置包括机器人卡处理装置，以在基于卡的交易期间能够读取用户卡。卡片感测装置位于远离读卡器的卡插槽附近。响应于感测插入的卡的卡感测装置，机器人卡处理装置操作以将卡夹在槽中并将其移动到读卡器中的读取位置。读卡器还可以在确定卡用户是否被授权使用卡的过程中与生物识别读取装置一起操作。机器人卡处理装置也可以被操作以抓住其他交易项目。

85. 发明申请

US20080219472A1 Noise suppressor 有权
标题翻译：噪声抑制器
公开(公告)号：US20080219472A1
公开(公告)日：2008-09-11
申请号：US11714746
申请日：2007-03-07
申请人： Harprit Singh Chhatwal , Hui Ll , Andrew Linkens , Mark Smith
发明人： Harprit Singh Chhatwal , Hui Ll , Andrew Linkens , Mark Smith
IPC分类号： H04B15/00
CPC分类号： G10L21/0208 , G10L2021/02168
摘要： A method of determining noise in an audio stream, the method comprising: acquiring a plurality of consecutive time frames of the audio stream each comprising samples of the audio stream; generating a discrete frequency spectrum for each frame responsive to the frame samples; partitioning the frequency spectrum of each frame into a plurality of same frequency bands; determining an audio energy for each frequency band in each frame; and determining an estimate of noise energy for each frequency band in a temporally last time frame responsive to a relatively small number of smallest values for the audio energy in the frequency band of the plurality of time frames.
摘要翻译：一种确定音频流中的噪声的方法，所述方法包括：获取音频流的多个连续时间帧，每个音频流包括音频流的采样; 响应于帧样本为每个帧生成离散频谱; 将每个帧的频谱划分成多个相同的频带; 确定每帧中每个频带的音频能量; 以及响应于所述多个时间帧中的频带中的音频能量的相对较小数量的最小值，在时间上最后一帧中确定每个频带的噪声能量的估计。

86. 发明授权

US07378402B2 Anti-viral nucleosides 失效
标题翻译：抗病毒核苷
公开(公告)号：US07378402B2
公开(公告)日：2008-05-27
申请号：US11208510
申请日：2005-08-22
申请人： Joseph Armstrong Martin , Keshab Sarma , David Bernard Smith , Mark Smith
发明人： Joseph Armstrong Martin , Keshab Sarma , David Bernard Smith , Mark Smith
IPC分类号： C07H19/00 , C07H19/06 , A01N43/04 , A61K31/70
CPC分类号： C07H19/06 , C07H19/067 , C07H19/12
摘要： 4-Amino-1-((2R,3S,4S,5R)-5-azido-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one (I:R1=R2=R3=R4=H) and prodrugs thereof are hepatitis C(HCV) polymerase inhibitors. Also disclosed are compositions and methods for inhibiting HCV and treating HCV-mediated diseases, processes for making the compounds and synthetic intermediates employed in the process.
摘要翻译： 4-氨基-1 - （（2R，3S，4S，5R）-5-叠氮基-3,4-二羟基-5-羟基甲基 - 四氢 - 呋喃-2-基）-1H-嘧啶-2-酮（I： R 1 = R 2 = R 3 = R 4 = H），其前药是丙型肝炎（HCV））聚合酶抑制剂。还公开了用于抑制HCV和治疗HCV介导的疾病的组合物和方法，用于制备该方法中使用的化合物和合成中间体的方法。

87. 发明申请

US20080051671A1 INTRAVASCULAR FILTER MONITORING 审中-公开
标题翻译：血管内滤器监测
公开(公告)号：US20080051671A1
公开(公告)日：2008-02-28
申请号：US11929007
申请日：2007-10-30
申请人： Thomas Broome , Anthony Vrba , Narin Anderson , Justin Crank , James Hansen , Horng-Ban Lin , Mark Smith
发明人： Thomas Broome , Anthony Vrba , Narin Anderson , Justin Crank , James Hansen , Horng-Ban Lin , Mark Smith
IPC分类号： A61B5/026
CPC分类号： A61B5/02158 , A61B5/02156 , A61F2/013
摘要： Devices and methods for monitoring the flow of blood through an intravascular device are disclosed. An apparatus for monitoring blood flow in accordance with an exemplary embodiment of the present invention includes an intravascular device coupled to an elongated member, a first sensor adapted to measure fluidic pressure proximal the intravascular device, a second sensor adapted to measure fluidic pressure distal the intravascular device, and a control unit for comparing the signals received from the first and second sensors to determine the pressure drop across the intravascular device.
摘要翻译：公开了通过血管内装置监测血流的装置和方法。根据本发明的示例性实施例的用于监测血流的装置包括联接到细长构件的血管内装置，适于测量血管内装置近侧的流体压力的第一传感器，适于测量血管内远端的流体压力的第二传感器装置和控制单元，用于比较从第一和第二传感器接收的信号，以确定穿过血管内装置的压降。

88. 发明申请

US20080012180A1 Methods For Creating Channels 失效
标题翻译：创建频道的方法
公开(公告)号：US20080012180A1
公开(公告)日：2008-01-17
申请号：US11857276
申请日：2007-09-18
申请人： Christopher Vitello , Steven Lunceford , Paul Nash , Marc Baldwin , Karen Martin , Mark Smith
发明人： Christopher Vitello , Steven Lunceford , Paul Nash , Marc Baldwin , Karen Martin , Mark Smith
IPC分类号： B29C35/08
CPC分类号： B41J2/16 , B41J2/1632 , B41J2/1637 , B41J2/1639 , Y10T29/42 , Y10T29/49087 , Y10T29/49099 , Y10T29/49117 , Y10T29/49128 , Y10T29/4913 , Y10T29/49401
摘要： Methods of creating an internal channel of a fluid-ejection device are provided. One method includes encapsulating a channel core in an element of the fluid-ejection device that corresponds to the internal channel and dissolving at least a portion of the channel core.
摘要翻译：提供了创建流体喷射装置的内部通道的方法。一种方法包括将通道芯封装在与内部通道对应的流体喷射装置的元件中并溶解通道芯的至少一部分。

89. 发明申请

US20070251668A1 HIGH TEMPERATURE REFRIGERATION CYCLE METHOD AND APPARATUS 审中-公开
标题翻译：高温制冷循环方法和装置
公开(公告)号：US20070251668A1
公开(公告)日：2007-11-01
申请号：US11691359
申请日：2007-03-26
申请人： Mark Smith
发明人： Mark Smith
IPC分类号： F25B13/00
CPC分类号： F25B30/00
摘要： A refrigeration apparatus for removing heat from a high temperature region. The refrigeration apparatus wherein the high temperature region is a stream of fluid having a temperature above 160 degrees Fahrenheit. The heat from the high temperature region is used to evaporate the refrigerant in a refrigeration cycle.
摘要翻译：一种用于从高温区域除去热量的制冷装置。其中高温区域是温度高于160华氏度的流体流的制冷装置。来自高温区域的热量用于在制冷循环中蒸发制冷剂。

90. 发明授权

US07259359B2 Automated glass entrance door assembly for walk-in coolers 有权
标题翻译：自动玻璃入口门组件，用于步入式冷却器
公开(公告)号：US07259359B2
公开(公告)日：2007-08-21
申请号：US11153159
申请日：2005-06-15
申请人： Jerry Davey , Mark Smith
发明人： Jerry Davey , Mark Smith
IPC分类号： H05B3/06
CPC分类号： H05B3/84 , A47F3/0404 , E06B3/4618
摘要： An automated glass cooler entrance door assembly for an opening in a walk-in cooler comprising at least one fixed, stationary side door that defines a walkway about the opening for ingress and egress into the cooler, at least one opposing sliding door operatively suspended from a concealed drive mechanism above the opening to slide sideways from a closed position across the opening to close-off the cooler to and from an opened position overlapping the fixed stationary side door to allow customer ingress and egress to the cooler via the walkway through the opening and each of the doors comprising heated glass that is electrically connected to electrical power to heat the same.
摘要翻译：一种用于步入式冷却器中的开口的自动玻璃冷却器入口门组件，包括至少一个固定的侧门，所述至少一个固定侧门限定了围绕所述开口的入口进入所述冷却器，至少一个相对的滑动门，其可操作地从在开口上方的隐藏的驱动机构从关闭位置横过开口侧向滑动以将冷却器关闭到与固定的固定侧门重叠的打开位置，以允许客户通过人行道通过开口进入和排出冷却器，并且每个门包括电连接到电力以加热玻璃的加热玻璃。

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