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81. 发明申请

US20100036949A1 Centralized Scheduler for Content Delivery Network 审中-公开
标题翻译：内容分发网络的集中式调度程序
公开(公告)号：US20100036949A1
公开(公告)日：2010-02-11
申请号：US12224680
申请日：2006-03-28
申请人： Jun Li , Snigdha Verma , Kumar Ramaswamy
发明人： Jun Li , Snigdha Verma , Kumar Ramaswamy
IPC分类号： G06F15/173
CPC分类号： H04L67/2819 , H04L41/509 , H04L67/28 , H04L67/322
摘要： A method for performing centralized scheduling of content delivery is described including performing admission control, locating a server that is a source of content, determining a content delivery schedule and reordering the content delivery schedule over a content delivery network (CDN). Also described is a method for performing admission control including reordering a request queue based on partially served committed requests for content and newly arrived requests for content and determining if the newly arrived request for content can be admitted to the request queue.
摘要翻译：描述了一种用于执行内容传送的集中调度的方法，包括执行准入控制，定位作为内容源的服务器，确定内容传送调度并通过内容传送网络（CDN）重新排序内容传递调度。还描述了一种用于执行准入控制的方法，包括基于对内容的部分服务的提交请求和新到达的内容请求重新排序请求队列，并确定新到达的内容请求是否可以被允许进入请求队列。

82. 发明申请

US20090324625A1 Heterocyclic Aromatic Compounds Useful As Growth Hormone Secretagogues 有权
标题翻译：用作生长激素秘密剂的杂环芳族化合物
公开(公告)号：US20090324625A1
公开(公告)日：2009-12-31
申请号：US12507430
申请日：2009-09-03
申请人： Guixue Yu , Jun Li , William R. Ewing , Richard B. Sulsky , James J. Li , Joseph Anthony Tino
发明人： Guixue Yu , Jun Li , William R. Ewing , Richard B. Sulsky , James J. Li , Joseph Anthony Tino
IPC分类号： A61K39/00 , A61K31/437
CPC分类号： C07D487/04 , C07D231/56 , C07D261/20 , C07D471/04 , C07D513/04
摘要： Novel heterocyclic aromatic compounds are provided that are useful in stimulating endogenous production or release of growth hormone, said compounds having the general structure of formula I wherein R1, R1′, R2, R3, R4, Xa, Y, Z and n are as described herein. The compounds provided herein are useful in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.
摘要翻译：提供了可用于刺激生长激素的内源性生产或释放的新型杂环芳族化合物，所述化合物具有式I的通式结构，其中R1，R1'，R2，R3，R4，Xa，Y，Z和n如上所述这里。本文提供的化合物可用于治疗肥胖症，骨质疏松症（改善骨密度）和改善肌肉质量和肌肉力量。

83. 发明申请

US20090319846A1 ADAPTIVE ERROR CORRECTION METHOD FOR DATA TRANSMISSION AND DEVICES THEREOF 审中-公开
标题翻译：用于数据传输的自适应纠错方法及其装置
公开(公告)号：US20090319846A1
公开(公告)日：2009-12-24
申请号：US12448536
申请日：2006-12-30
申请人： Xiaojun Ma , Jun Li , Hang Liu
发明人： Xiaojun Ma , Jun Li , Hang Liu
IPC分类号： G06F11/07 , H04H20/71
CPC分类号： H04L1/1621 , H04H60/11 , H04L1/1877 , H04L1/1883 , H04L1/1887 , H04L12/1827 , H04L12/1868 , H04L2001/0093
摘要： An adaptive error correction method for data transmission and the devices thereof are disclosed. By comparing the announced recovery data and data requested for error correction, no redundant join messages will be sent if the recovery data have been announced before. This will greatly reduce the number messages and save the band width of transmission.
摘要翻译：公开了一种用于数据传输的自适应纠错方法及其装置。通过比较所公布的恢复数据和纠错请求的数据，如果恢复数据已经公布，则不会发送冗余加入消息。这将大大减少数字消息并节省传输带宽。

84. 发明授权

US07592354B2 Heterocyclic aromatic compounds useful as growth hormone secretagogues 有权
标题翻译：用作生长激素促分泌素的杂环芳族化合物
公开(公告)号：US07592354B2
公开(公告)日：2009-09-22
申请号：US11273169
申请日：2005-11-14
申请人： Guixue Yu , Jun Li , William R. Ewing , Richard B. Sulsky , James J. Li , Joseph Anthony Tino
发明人： Guixue Yu , Jun Li , William R. Ewing , Richard B. Sulsky , James J. Li , Joseph Anthony Tino
IPC分类号： A61K31/395 , C07D487/02
CPC分类号： C07D487/04 , C07D231/56 , C07D261/20 , C07D471/04 , C07D513/04
摘要： Novel heterocyclic aromatic compounds are provided that are useful in stimulating endogenous production or release of growth hormone, said compounds having the general structure of formula I wherein R1, R1′, R2, R3, R4, Xa, Y, Z and n are as described herein. The compounds provided herein are useful in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.
摘要翻译：提供了可用于刺激生长激素的内源性生产或释放的新型杂环芳族化合物，所述化合物具有式I的通式结构，其中R1，R1'，R2，R3，R4，Xa，Y，Z和n如上所述这里。本文提供的化合物可用于治疗肥胖症，骨质疏松症（改善骨密度）和改善肌肉质量和肌肉力量。

85. 发明申请

US20090233842A1 FGF2-RELATED METHODS FOR DIAGNOSING AND TREATING DEPRESSION 审中-公开
标题翻译： FGF2相关方法诊断和治疗抑郁症
公开(公告)号：US20090233842A1
公开(公告)日：2009-09-17
申请号：US12093437
申请日：2006-11-13
申请人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William E. Bunney, JR. , Marquis P. Vawter , Edward G. Jones , Prabhakara V. Choudary , Richard M. Myers , Alan F. Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
发明人： Huda Akil , Stanley J. Watson , Simon J. Evans , Cortney Turner , Rene Bernard , Ilan Kerman , Robert C. Thompson , Margit Burmeister , Laura J. Scott , Fan Meng , Michael Boehnke , William E. Bunney, JR. , Marquis P. Vawter , Edward G. Jones , Prabhakara V. Choudary , Richard M. Myers , Alan F. Schatzberg , Jun Li , Devin Absher , Hiroaki Tomita
IPC分类号： A61K38/00 , C12Q1/68
CPC分类号： C12Q1/6883 , A61K38/03 , A61K38/10 , A61K38/1774 , A61K38/1825 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , G01N33/5023 , G01N2800/304
摘要： The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic markers and assays, as well as research tools for the development and discovery of agents and compounds which are useful for treating patients who suffer from mental illness.
摘要翻译：本申请涉及心理障碍的治疗和诊断，包括双相情感障碍，重症抑郁障碍和精神分裂症。本发明提供了新的诊断标记和测定，以及用于开发和发现可用于治疗患有精神疾病的患者的药剂和化合物的研究工具。

86. 发明授权

US07586315B2 System and method for testing voltage endurance 有权
标题翻译：用于测试耐电压的系统和方法
公开(公告)号：US07586315B2
公开(公告)日：2009-09-08
申请号：US11836795
申请日：2007-08-10
申请人： Shih-Fang Wong , Tsung-Jen Chuang , Jun Li
发明人： Shih-Fang Wong , Tsung-Jen Chuang , Jun Li
IPC分类号： G01R27/08
CPC分类号： G01R31/3004 , G01R31/2839
摘要： A method for testing voltage endurance of a electronic component, includes: generating an oscillating signal; amplifying the oscillating signal; transforming the amplified oscillating signal to generate a transformed signal; blocking a negative voltage of the transformed signal to generate a test signal to be transmitted to the electronic component; and detecting electrical characteristics of the electronic component to generate result data.
摘要翻译：一种用于测试电子部件的耐压性的方法，包括：产生振荡信号; 放大振荡信号; 变换放大的振荡信号以产生变换信号; 阻断变换后的信号的负电压以产生要发送到电子部件的测试信号; 并检测电子部件的电气特性以产生结果数据。

87. 发明授权

US07579360B2 Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors 有权
标题翻译：三唑并吡啶11-β羟基类固醇脱氢酶I型抑制剂
公开(公告)号：US07579360B2
公开(公告)日：2009-08-25
申请号：US11448947
申请日：2006-06-07
申请人： James J. Li , Lawrence G. Hamann , Haixia Wang , Zheming Ruan , Christopher B. Cooper , Jun Li , Jeffrey A. Robl
发明人： James J. Li , Lawrence G. Hamann , Haixia Wang , Zheming Ruan , Christopher B. Cooper , Jun Li , Jeffrey A. Robl
IPC分类号： A01N43/42 , A61K31/44 , C07D513/02 , C07D515/02
CPC分类号： C07D471/04
摘要： Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein W, L, R3, R3a, R3b and R4 are defined herein.
摘要翻译：提供了新的化合物，其为11-β-羟基类固醇脱氢酶I型抑制剂。 11-β-羟基类固醇脱氢酶I型抑制剂可用于治疗，预防或减缓需要11-β-羟基类固醇脱氢酶I型抑制剂治疗的疾病进展。这些新化合物具有以下结构：其立体异构体或前药或其药学上可接受的盐，其中W，L，R3，R3a，R3b和R4如本文所定义。

88. 发明申请

US20090186010A1 METHODS FOR THE IDENTIFICATION OF IKKALFA FUNCTION AND OTHER GENES USEFUL FOR TREATMENT OF INFLAMMATORY DISEASES 审中-公开
标题翻译：用于鉴定IKKALFA功能的方法和其他有助于治疗炎症疾病的基因
公开(公告)号：US20090186010A1
公开(公告)日：2009-07-23
申请号：US12271198
申请日：2008-11-14
申请人： Jun Li , Adedayo Hanidu , Xiang Li , Gregory Whitten Peet , Sheenah Mische , Kenneth Marcu
发明人： Jun Li , Adedayo Hanidu , Xiang Li , Gregory Whitten Peet , Sheenah Mische , Kenneth Marcu
IPC分类号： A61K38/43 , C12Q1/68 , A61K38/46 , A61K38/16 , A61K38/02 , A61P37/06
CPC分类号： C12Q1/6883 , C12Q2600/158 , G01N33/5023
摘要： The invention provides a method for identifying genes involved in the NF-κB pathway comprised of the steps of determining the level of expression of a gene in an experimental sample obtained from the cells having deficient levels of a component of the NF-κB pathway; determining the level of expression of said gene in a control sample obtained from wild type cells having levels of a component of a biological pathway; selecting genes having a level of expression that are modulated in said experimental sample relative to said wild type sample. The invention also provides a method of treating inflammatory related diseases by modulating the activity of IKKα.
摘要翻译：本发明提供了鉴定涉及NF-κB途径的基因的方法，其包括确定从具有NF-κB途径成分水平不足的细胞获得的实验样品中基因表达水平的步骤; 确定从具有生物学途径成分水平的野生型细胞获得的对照样品中所述基因的表达水平; 选择具有相对于所述野生型样品在所述实验样品中调节的表达水平的基因。本发明还提供了通过调节IKKα的活性来治疗炎性相关疾病的方法。

89. 发明申请

US20090157369A1 Fast and High-Throughput Search Engine for Materials for Lithium-Ion Batteries Using Quantum Simulations 审中-公开
标题翻译：使用量子模拟的锂离子电池材料快速高通量搜索引擎
公开(公告)号：US20090157369A1
公开(公告)日：2009-06-18
申请号：US12334170
申请日：2008-12-12
申请人： Jun Li , Deepak Srivastava
发明人： Jun Li , Deepak Srivastava
IPC分类号： G06G7/58
CPC分类号： G16C10/00 , G16C60/00 , H01M4/485 , H01M4/505 , H01M4/525 , H01M10/0525
摘要： Provided are methods and systems for determining the structure of a composite or solid solution material for an electrode in lithium-ion batteries. In one embodiment, a method is presented where a building-block database of hypothetical structures containing only one transition metal atom is constructed by use of quantum simulation. Then, a composite model set of structures containing two or more transition metal atoms is constructed by calculating a linear average of parent components from the building-block database of hypothetical structures to determine lattice constants and atomic coordinates of candidates. The composite model set is screened with a local order matrix to subclassify composite models into a subset, such that the composite models share the same property in local transition metal ordering. Still yet, a representative from each subset is selected and a quantum simulation on the representative models is performed to determine the structure of the material.
摘要翻译：提供了用于确定锂离子电池中的电极的复合材料或固溶体材料的结构的方法和系统。在一个实施例中，提出了一种方法，其中通过使用量子模拟构建仅包含一个过渡金属原子的假想结构的构建块数据库。然后，通过从假设结构的构建块数据库中计算母体成分的线性平均值来确定候选物的晶格常数和原子坐标来构建包含两个或更多个过渡金属原子的结构的复合模型集合。复合模型集用局部顺序矩阵进行筛选，将复合模型分类为子集，使得复合模型在本地过渡金属排序中共享相同的属性。仍然选择来自每个子集的代表，并且对代表性模型进行量子模拟以确定材料的结构。

90. 发明授权

US07524446B2 Method for manufacturing a composite tire of polyurethane tread and radial carcase 有权
标题翻译：聚氨酯胎面和径向车箱复合轮胎的制造方法
公开(公告)号：US07524446B2
公开(公告)日：2009-04-28
申请号：US10875672
申请日：2004-06-23
申请人： Hai Zhang , Tie-Jun Ma , Yan-Ping Ye , Yu-Hua Yi , Jian-Rong Shen , Jun Li
发明人： Hai Zhang , Tie-Jun Ma , Yan-Ping Ye , Yu-Hua Yi , Jian-Rong Shen , Jun Li
IPC分类号： B29C39/10
CPC分类号： C08G18/7678 , B29D30/52 , B29K2075/00 , B60C1/00 , B60C1/0016 , C08G18/10 , C08G18/12 , C08G18/4854 , C08G18/69 , C08G18/698 , C08G2380/00 , C08K3/04 , C08K3/36 , C08K9/06 , C08L2666/54 , C09J175/04 , Y02T10/862 , Y10S264/77 , C08G18/3203 , C08G18/3893
摘要： Methods for manufacturing a composite rubber tire with a polyurethane tread comprise: treating an outer surface of an internal rubber body; preparing a polyurethane pre-polymer; improving the polyurethane pre-polymer; and applying the polyurethane pre-polymer to the treated outer surface of the internal rubber body to mold a polyurethane tread. Thereby, the composite rubber tire with the polyurethane tread is achieved and has excellent characteristics such as low rolling resistance, low oil consumption, excellent durability and low environmental contamination. Additionally, the methods constitute simple manufacturing processes that reduce manufacturing costs of the composite rubber tire with the polyurethane tread.
摘要翻译：制造具有聚氨酯胎面的复合橡胶轮胎的方法包括：处理内部橡胶体的外表面; 制备聚氨酯预聚物; 改进聚氨酯预聚物; 并将聚氨酯预聚物施加到内部橡胶体的经处理的外表面上以模制聚氨酯胎面。由此，实现了具有聚氨酯胎面的复合橡胶轮胎，并且具有低滚动阻力，低油耗，优异的耐久性和低环境污染等优异的特性。另外，这些方法构成简单的制造工艺，其降低了具有聚氨酯胎面的复合橡胶轮胎的制造成本。

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