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81. 发明申请

US20080033241A1 LEFT ATRIAL APPENDAGE CLOSURE 审中-公开
标题翻译：左侧附件关闭
公开(公告)号：US20080033241A1
公开(公告)日：2008-02-07
申请号：US11828281
申请日：2007-07-25
申请人： Ruey-Feng Peh , Vahid Saadat
发明人： Ruey-Feng Peh , Vahid Saadat
IPC分类号： A61B1/00 , A61B17/128
CPC分类号： A61B1/3137 , A61B1/0008 , A61B1/00082 , A61B1/00089 , A61B1/00179 , A61B5/6882 , A61B17/0057 , A61B17/0469 , A61B17/0644 , A61B17/12122 , A61B2017/00345 , A61B2017/00575 , A61B2017/0409 , A61B2017/0443 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0649 , A61B2017/306
摘要： Methods and apparatus for intraluminally or transluminally closing a left atrial appendage while under direct visualization are described herein. Such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for performing any number of procedures on the tissue for accessing and closing the left atrial appendage.
摘要翻译：本文描述了在直接可视化期间内壁或平滑闭合左心耳的方法和装置。这样的系统可以包括部署导管和可展开成扩展配置的附接成像罩。在使用中，成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。半透明或透明的液体（例如盐水）可被泵送到成像罩中，直到流体移动任何血液，从而留下通过展开导管中的成像元件成像的组织的清晰区域。此外，任何数量的治疗工具也可以通过展开导管并进入成像罩，用于在组织上执行用于访问和关闭左心耳的任何数量的程序。

82. 发明申请

US20070225781A1 Apparatus and methods for altering temperature in a region within the body 审中-公开
标题翻译：用于改变体内区域温度的装置和方法
公开(公告)号：US20070225781A1
公开(公告)日：2007-09-27
申请号：US11386239
申请日：2006-03-21
申请人： Vahid Saadat , Lorns G. Eltherington
发明人： Vahid Saadat , Lorns G. Eltherington
IPC分类号： A61F7/00
CPC分类号： A61F7/12 , A61B2017/00084 , A61F2007/0056 , A61F2007/0076 , A61F2007/0094
摘要： Apparatus and methods for cooling and/or heating selected regions within a body are described herein. An implantable system is used to cool or heat nerve bodies down to about 15° C. to diminish nerve impulses. In one embodiment, the system can include an implantable unit containing a pumping mechanism and/or various control electronics. The system has a cooling element. The cooling element can be a Peltier junction or a catheter through which hot or cold fluid flows. The heated portion of the Peltier junction can be cooled by a liquid heat transfer medium which absorbs the heat from the junction and dissipates the heat elsewhere.
摘要翻译：本文描述了用于冷却和/或加热体内所选区域的装置和方法。使用可植入系统将神经体冷却或加热至约15℃，以减少神经冲动。在一个实施例中，系统可以包括含有泵送机构和/或各种控制电子装置的可植入单元。该系统具有冷却元件。冷却元件可以是热或冷流体流过的珀尔帖接头或导管。珀尔帖接头的加热部分可以通过液体传热介质进行冷却，液体传热介质吸收来自接头的热量，并将热量散发到别处。

83. 发明申请

US20070167828A1 TISSUE IMAGING SYSTEM VARIATIONS 有权
标题翻译：组织成像系统变化
公开(公告)号：US20070167828A1
公开(公告)日：2007-07-19
申请号：US11560742
申请日：2006-11-16
申请人： Vahid Saadat
发明人： Vahid Saadat
IPC分类号： A61B8/14
CPC分类号： A61B1/005 , A61B1/0008 , A61B1/00082 , A61B1/00085 , A61B1/00089 , A61B1/015 , A61B1/018 , A61B1/04 , A61B5/0031 , A61B5/02007 , A61B5/6882 , A61B8/12 , A61B2018/0212
摘要： Tissue imaging system variations are described herein. Such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, the system can be deployed in a number of various ways such as clearing blood clots, emboli, and other debris which may be present in a body lumen. Other variations may also be used for facilitating trans-septal access across tissue regions as well as for balancing body fluids during a procedure.
摘要翻译：本文描述了组织成像系统的变化。这样的系统可以包括部署导管和可展开成扩展配置的附接成像罩。在使用中，成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。半透明或透明的液体（例如盐水）可被泵送到成像罩中，直到流体移动任何血液，从而留下通过展开导管中的成像元件成像的组织的清晰区域。此外，该系统可以以多种各种方式进行部署，例如清除血液凝块，栓塞以及可能存在于体腔内的其它碎片。也可以使用其它变化来促进跨组织区域的间隔隔离以及用于在手术过程中平衡体液。

84. 发明授权

US07186262B2 Apparatus and methods for treating tissue 有权
标题翻译：用于治疗组织的装置和方法
公开(公告)号：US07186262B2
公开(公告)日：2007-03-06
申请号：US10188509
申请日：2002-07-03
申请人： Vahid Saadat
发明人： Vahid Saadat
IPC分类号： A61B17/04 , A61F2/06
CPC分类号： A61B18/00 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/122 , A61B17/1285 , A61B17/29 , A61B18/1442 , A61B18/1477 , A61B18/1492 , A61B18/24 , A61B90/39 , A61B2017/00084 , A61B2017/00243 , A61B2017/00867 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0427 , A61B2017/0437 , A61B2017/044 , A61B2017/0451 , A61B2017/0454 , A61B2017/0458 , A61B2017/0461 , A61B2017/0464 , A61B2017/0496 , A61B2017/2945 , A61B2018/00023 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00232 , A61B2018/00273 , A61B2018/00369 , A61B2018/00791 , A61B2018/00797 , A61B2018/1253 , A61B2018/126 , A61B2018/1432 , A61B2018/1435 , A61B2090/064 , A61F2/2445 , A61F2/2451 , A61F2/2454 , A61N7/00 , A61N7/02
摘要： Apparatus and methods are provided for thermally and/or mechanically treating tissue, such as valvular structures, to reconfigure or shrink the tissue in a controlled manner. Mechanical clips are implanted over the leaflets of a valve, e.g., in the heart, either alone or after thermal treatment to cause the valve to close more tightly. The clips are delivered by a catheter and may be configured to traverse directly over the valve itself or to lie partially over the periphery of the valve to prevent obstruction of the valve channel. The clips can be coated with drugs or a radiopaque coating. Alternatively, individual anchors with a tensioning element, like a suture, may be used to approximate the valves towards each other. The catheter can also incorporate sensors or energy delivery devices, e.g., transducers, on its distal end.
摘要翻译：提供了用于热和/或机械处理组织（例如瓣结构）的设备和方法，以受控的方式重新配置或收缩组织。将机械夹子单独地或在热处理之后植入例如心脏的瓣膜的小叶上，以使阀门更紧密地闭合。夹子由导管递送，并且可以被配置成直接在阀本身上移动或部分地位于阀的周边上以防止阀通道的阻塞。夹子可以涂上药物或不透射线的涂层。或者，可以使用具有诸如缝合线的张紧元件的单个锚定件来朝向彼此近似阀。导管还可以在其远端上并入传感器或能量输送装置，例如换能器。

85. 发明申请

US20060258909A1 Methods and apparatus for maintaining sterility during transluminal procedures 审中-公开
标题翻译：在宫腔手术过程中保持不育的方法和装置
公开(公告)号：US20060258909A1
公开(公告)日：2006-11-16
申请号：US11400297
申请日：2006-04-07
申请人： Vahid Saadat , John Cox , Tracy Maahs
发明人： Vahid Saadat , John Cox , Tracy Maahs
IPC分类号： A61B1/00
CPC分类号： A61B17/3431 , A61B1/00142 , A61B17/064 , A61B17/08 , A61B17/3496 , A61B46/10 , A61B46/17 , A61B90/40 , A61B2017/00278 , A61B2017/0419 , A61B2017/0647 , A61B2017/0649 , A61B2017/3488
摘要： Methods and apparatus for maintaining sterility during transluminal procedures are described. The sterility is achieved by making use of a membrane in either the form, e.g., of a sheath, cap or umbrella to keep the instruments (endoscopes, overtubes, etc.) sterile while being advanced through lumens in the body and into the various cavities. Methods, such as vacuum acquisition, mechanical tissue anchoring, etc., of the underlying tissue followed by incision of the tissue with, e.g., a needle knife, can be utilized to gain access to the various cavities. It is expected that this procedure will provide the desired level of sterility for transluminal procedures.
摘要翻译：描述了在腔内程序中维持不育的方法和装置。通过使用例如护套，帽或伞的形式的膜来实现无菌性，以将器具（内窥镜，超声波管等）保持无菌，同时通过体内的腔进入各种空腔。可以使用诸如真空采集，机械组织锚定等方法，随后用例如针刀切割组织的下面的组织，以便进入各种空腔。预期该程序将为腔内程序提供所需的无菌水平。

86. 发明申请

US20060200062A1 Multi-barbed device for retaining tissue in apposition and methods of use 审中-公开
公开(公告)号：US20060200062A1
公开(公告)日：2006-09-07
申请号：US11343924
申请日：2006-01-30
申请人： Vahid Saadat
发明人： Vahid Saadat
IPC分类号： A61F15/00
CPC分类号： A61F2/4455 , A61B17/08 , A61B17/11 , A61B2017/00004 , A61B2017/081 , A61B2017/1103 , A61F2/0063 , A61F2/06 , A61F2/064 , A61F2/08 , A61F2/30756 , A61F2/30767 , A61F2/389 , A61F2/442 , A61F2/4618 , A61F2002/30784 , A61F2002/30841 , A61F2002/30892 , A61F2002/30894 , A61F2002/4628 , A61F2002/4635 , A61F2002/4681 , A61F2310/00796 , A61F2310/00976 , A61L31/16 , A61L2300/414 , A61L2300/418
摘要： A multi-barbed apparatus is provided, and methods of use, for penetrating two sides of a wound and holding the edges in apposition. The apparatus may be inserted within a wound or underneath the skin, and mechanically adheres the two sides of the wound together. The apparatus includes a biocompatible substrate carrying a multiplicity of tissue penetrating barbs on a least one side thereof, and may be formed as a rigid or flexible sheet, tube or other shape.

87. 发明申请

US20060183975A1 Methods and apparatus for performing endoluminal procedures 审中-公开
标题翻译：用于进行腔内手术的方法和装置
公开(公告)号：US20060183975A1
公开(公告)日：2006-08-17
申请号：US11400580
申请日：2006-04-07
申请人： Vahid Saadat , Chris Rothe , Richard Ewers , Gilbert Madrid
发明人： Vahid Saadat , Chris Rothe , Richard Ewers , Gilbert Madrid
IPC分类号： A61B1/00
CPC分类号： A61B1/0051 , A61B1/0008 , A61B1/00179 , A61B1/00183 , A61B1/018 , A61B1/04 , A61B17/29
摘要： Methods and apparatus for performing endoluminal procedures are described herein. An endoluminal tissue manipulation assembly is disclosed which provides for a stable endoluminal platform and which also provides for effective triangulation of tools. Such an apparatus may comprise an optionally shape-lockable elongate body defining a longitudinal axis and adapted for endoluminal advancement in a patient body, at least one articulatable visualization lumen disposed near or at a distal region of the elongate body, the at least one articulating visualization lumen being adapted to articulate off-axis relative to a longitudinal axis of the elongate body, and at least one articulatable tool arm member disposed near or at the distal region of the elongate body, the at least one articulatable tool arm member being adapted to articulate off-axis and manipulate a tissue region of interest.
摘要翻译：本文描述了用于进行腔内手术的方法和装置。公开了一种腔内组织操作组件，其提供稳定的内腔平台，并且还提供工具的有效三角测量。这种装置可以包括限定纵向轴线并且适于在患者体内进行腔内前进的可选形状可锁定细长体，至少一个可伸长的可视腔，其设置在细长体的远端区域附近或位于该远端区域处，该至少一个铰接可视化内腔适于相对于细长主体的纵向轴线偏轴关节，以及设置在细长主体的远侧区域附近或其附近的至少一个可铰接工具臂构件，所述至少一个可铰接工具臂构件适于铰接离轴并且操纵感兴趣的组织区域。

88. 发明申请

US20060036267A1 Methods and apparatus for performing malabsorptive bypass procedures within a patient's gastro-intestinal lumen 审中-公开
标题翻译：在患者胃肠腔内进行吸收不良的旁路手术的方法和装置
公开(公告)号：US20060036267A1
公开(公告)日：2006-02-16
申请号：US10916768
申请日：2004-08-11
申请人： Vahid Saadat , Richard Ewers , Ruey-Feng Peh
发明人： Vahid Saadat , Richard Ewers , Ruey-Feng Peh
IPC分类号： A61B17/08
CPC分类号： A61B17/1114 , A61B17/11 , A61B2017/00349 , A61B2017/00876 , A61B2017/0409 , A61B2017/1103 , A61B2017/1117
摘要： Methods and apparatus for performing malabsorptive bypass procedures within a patient's gastrointestinal lumen are described comprising, for example, gastroenterostomy procedures that are preferably performed in an endoscopic or laparoscopic fashion. Anastomosis between the patient's stomach and intestine allows food to bypass at least a portion of the patient's stomach and/or intestine, thereby providing a malabsorptive region. The malabsorptive procedure may be accompanied by additional procedures, for example, pyloric occlusion, pyloroplasty, gastroplasty, gastric tissue destruction and/or intestinal pleating.
摘要翻译：描述了在患者的胃肠腔内进行吸收不良手术的方法和装置，其包括例如胃肠造口术程序，其优选以内窥镜或腹腔镜方式进行。患者胃和肠之间的吻合允许食物绕过患者的胃和/或肠的至少一部分，从而提供吸收不良的区域。吸收不良的程序可伴随其他方法，例如幽门闭塞，成形术，胃成形术，胃组织破坏和/或肠打褶。

89. 发明申请

US20060020274A1 Manipulatable grasping needle 审中-公开
标题翻译：可操纵抓针
公开(公告)号：US20060020274A1
公开(公告)日：2006-01-26
申请号：US10898684
申请日：2004-07-23
申请人： Richard Ewers , Cang Lam , Vahid Saadat
发明人： Richard Ewers , Cang Lam , Vahid Saadat
IPC分类号： A61B17/04
CPC分类号： A61B17/29 , A61B17/0401 , A61B17/0469 , A61B17/0483 , A61B2017/00349 , A61B2017/2905 , A61B2017/2926
摘要： A manipulatable grasping needle is described herein. A piercing and grasping assembly generally comprises a needle body, which is optionally hollow, having a piercing tip and a grasping arm positioned proximally of the tip, wherein the grasping arm is adapted to project from the needle body and releasably retain a length of suture. Alternatively, opposing jaws can form a singular piercing tip when the jaws are closed. The assembly is positioned at the distal end of an elongate member which can be rigid or flexible for advancement through an endoscopic device. The elongate member can also comprise one or more articulatable sections to enable manipulation of the assembly into various shapes to facilitate suture and tissue manipulation. Moreover, either the needle body or grasping arm can define a notch for receiving suture material. A hooking member can also be provided to facilitate suture retrieval when grasping suture.
摘要翻译：这里描述了可操纵的把持针。穿刺和抓握组件通常包括可选地中空的针体，其具有穿刺尖端和位于尖端近侧的抓握臂，其中抓握臂适于从针体突出并且可释放地保持一定长度的缝合线。或者，当夹爪关闭时，相对的夹爪可以形成单个穿刺尖端。组件定位在细长构件的远端，细长构件的远端可以是刚性的或柔性的，用于通过内窥镜装置前进。细长构件还可以包括一个或多个可铰接部分，以使得能够将组件操纵成各种形状以便于缝合和组织操纵。此外，针体或抓握臂可以限定用于接收缝合材料的凹口。还可以提供钩构件以便于在抓住缝线时促进缝合线的取出。

90. 发明申请

US20050277975A1 Methods and apparatus for creating a working space within a body lumen or cavity 审中-公开
标题翻译：用于在体腔或腔内产生工作空间的方法和装置
公开(公告)号：US20050277975A1
公开(公告)日：2005-12-15
申请号：US10865686
申请日：2004-06-09
申请人： Vahid Saadat , Chris Rothe , Ruey-Feng Peh
发明人： Vahid Saadat , Chris Rothe , Ruey-Feng Peh
IPC分类号： A61B17/02 , A61B17/34 , A61M29/00
CPC分类号： A61B17/0218 , A61B2017/3484 , A61B2017/3488
摘要： Methods and apparatus for creating a working space within a patient's stomach are described. The working space is created by internally spreading or pushing the walls of the stomach apart. Advantageously, such spreading is achieved without pressurizing the patient's stomach, i.e. without injecting a pressurized gas or other fluid directly into the stomach. Diagnostic or therapeutic instruments may be deployed within the working space. It is expected that spreading the walls without pressurizing the stomach will facilitate engagement and/or manipulation of the stomach wall for, e.g., endoluminal treatment of obesity.
摘要翻译：描述了在患者胃内创建工作空间的方法和装置。工作空间是通过内部扩展或推开胃壁而产生的。有利地，在不对患者的胃进行加压的情况下实现这种扩散，即不将加压气体或其它流体直接注入到胃中。诊断或治疗仪器可以部署在工作空间内。预期在不加压胃的情况下扩散壁将有助于胃壁的接合和/或操纵，例如用于肥胖的腔内处理。

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