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81. 发明申请

US20120215294A1 CORONARY VEIN LEADS HAVING PRE-FORMED BIASED PORTIONS FOR FIXATION 有权
标题翻译：具有用于固定的预先形成的偏心部分的冠状动脉引导
公开(公告)号：US20120215294A1
公开(公告)日：2012-08-23
申请号：US13251466
申请日：2011-10-03
申请人： Avram Scheiner , Ronald W. Heil , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren , Christina Repasky , Lyle A. Bye , Brian D. Soltis
发明人： Avram Scheiner , Ronald W. Heil , Peter T. Kelley , Bruce Tockman , Randy Westlund , Jay A. Warren , Christina Repasky , Lyle A. Bye , Brian D. Soltis
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/057 , A61N2001/0585
摘要： A lead having a pre-formed biased portion is adapted for implantation with a body vessel and for connection to a signal generator. The lead is constructed and arranged so that when it is implanted, the electrodes are biased toward a vessel wall by the preformed biased portion, which operates to fixate the lead against the vessel wall.
摘要翻译：具有预成形的偏置部分的引线适于用身体容器注入并连接到信号发生器。引线被构造和布置成使得当其被植入时，电极通过预先形成的偏压部分朝向血管壁偏压，该部分操作以将引线固定在血管壁上。

82. 发明授权

US08229563B2 Devices for adapting charge initiation for an implantable cardioverter-defibrillator 有权
标题翻译：适用于植入式心律转复除颤器的充电开始装置
公开(公告)号：US08229563B2
公开(公告)日：2012-07-24
申请号：US11043012
申请日：2005-01-25
申请人： Jay A. Warren , Gust H. Bardy
发明人： Jay A. Warren , Gust H. Bardy
IPC分类号： A61N1/362
CPC分类号： A61N1/3943 , A61N1/3956
摘要： Devices configured to perform an adaptive method for initiating charging of high power capacitors and delivering therapy to a patient after the patient experiences a non-sustained arrhythmia. The adaptive methods adjust persistence criteria used to analyze an arrhythmia prior to initiating a charging sequence to deliver therapy.
摘要翻译：被配置为执行自适应方法的装置，用于启动高功率电容器的充电并且在患者经历不持续性心律失常之后向患者递送治疗。适应性方法调整持续性标准，用于在启动充电序列之前分析心律失常以提供治疗。

83. 发明授权

US08073532B2 Method and apparatus for beat alignment and comparison 有权
标题翻译：拍子对准和比较的方法和装置
公开(公告)号：US08073532B2
公开(公告)日：2011-12-06
申请号：US12353114
申请日：2009-01-13
申请人： Surekha Palreddy , Jay A. Warren , Alan H. Ostroff
发明人： Surekha Palreddy , Jay A. Warren , Alan H. Ostroff
IPC分类号： A61N1/365
CPC分类号： A61B5/04525 , A61B5/0464 , A61N1/3622 , A61N1/3956 , Y10S128/92
摘要： Methods of using a template having a template data set and template parameters to provide improved alignment of captured cardiac signal data to a stored template. More particularly, in an illustrative method, a captured cardiac signal is first configured using template parameters for a stored template. Then, once configured, the captured cardiac signal is then compared to the stored template. Other embodiments include implantable cardiac treatment devices including operational circuitry configured to perform the illustrative method. In a further embodiment, more than one stored templates may be used. Each template can have independently constructed parameters, such that a single captured cardiac signal may be configured using first parameters for comparison to a first template, and using second parameters for comparison to a second template.
摘要翻译：使用具有模板数据集和模板参数的模板的方法来提供捕获的心脏信号数据与存储的模板的改进对准。更具体地，在说明性方法中，首先使用用于存储的模板的模板参数来配置捕获的心脏信号。然后，一旦配置，捕获的心脏信号然后与存储的模板进行比较。其他实施例包括可植入心脏治疗装置，其包括被配置为执行说明性方法的操作电路。在另一实施例中，可以使用多于一个的存储的模板。每个模板可以具有独立构造的参数，使得可以使用用于与第一模板进行比较的第一参数以及使用用于与第二模板进行比较的第二参数来配置单个捕获的心脏信号。

84. 发明申请

US20110282406A1 Method and Devices for Performing Cardiac Waveform Appraisal 有权
标题翻译：执行心脏波形评估的方法和设备
公开(公告)号：US20110282406A1
公开(公告)日：2011-11-17
申请号：US13189386
申请日：2011-07-22
申请人： Surekha Palreddy , Jay A. Warren , James W. Phillips
发明人： Surekha Palreddy , Jay A. Warren , James W. Phillips
IPC分类号： A61N1/39 , A61N1/365
CPC分类号： A61N1/365 , A61B5/0031 , A61B5/0422 , A61B5/04525 , A61B5/7207 , A61B5/7239 , A61N1/3622 , A61N1/368
摘要： Implementations of various technologies described herein are directed toward a sensing architecture for use in cardiac rhythm management devices. The sensing architecture may provide a method and means for certifying detected events by the cardiac rhythm management device. Moreover, by exploiting the enhanced capability to accurately identifying only those sensed events that are desirable, and preventing the use of events marked as suspect, the sensing architecture can better discriminate between rhythms appropriate for device therapy and those that are not.
摘要翻译：本文描述的各种技术的实现针对用于心律管理装置的感测架构。感测架构可以提供用于通过心律管理装置认证检测到的事件的方法和装置。此外，通过利用增强的能力来准确地仅识别那些感兴趣的事件，并且防止使用标记为可疑的事件，感测体系结构可以更好地区分适合于设备治疗的节律和不适合于设备治疗的节律。

85. 发明授权

US07983749B2 Cardiac rhythm management system with time-dependent frequency response 有权
标题翻译：具有时间依赖性频率响应的心律管理系统
公开(公告)号：US07983749B2
公开(公告)日：2011-07-19
申请号：US10615636
申请日：2003-07-10
申请人： Jay A. Warren
发明人： Jay A. Warren
IPC分类号： A61N1/362
CPC分类号： A61N1/362
摘要： A cardiac rhythm management system includes a time-dependent frequency response for sensed heart signals. A change in the frequency response of a sensing circuit is triggered by a sensed or evoked event to make it less sensitive to the detection of a subsequent event for a period of time. For example, a passband bandwidth is reduced, then increased during the time period triggered by the event. For even more event-triggered selectivity, a gain is reduced, then increased during the time period triggered by the event. This provides better discrimination between particular events included in a heart signal so that appropriate therapy can be delivered to the patient based such events.
摘要翻译：心律管理系统包括对感测到的心脏信号的时间依赖性频率响应。感测电路的频率响应的变化由感测或诱发的事件触发，以使其对一段时间后续事件的检测不那么敏感。例如，通带带宽减小，然后在由事件触发的时间段期间增加。对于更多的事件触发选择性，减少增益，然后在事件触发的时间段内增加。这提供了包括在心脏信号中的特定事件之间的更好的区分，使得可以基于这样的事件向患者传递适当的治疗。

86. 发明申请

US20090131998A1 Method for Adapting Charge Initiation for an Implantable Cardioverter-Defibrillator 有权
标题翻译：适用于植入式心律转复除颤器电荷起始的方法
公开(公告)号：US20090131998A1
公开(公告)日：2009-05-21
申请号：US12359072
申请日：2009-01-23
申请人： Jay A. Warren , Gust H. Bardy
发明人： Jay A. Warren , Gust H. Bardy
IPC分类号： A61N1/39
CPC分类号： A61N1/3621 , A61N1/3943 , A61N1/3956
摘要： Adaptive methods for initiating charging of the high power capacitors of an implantable medical device for therapy delivery after the patient experiences a non-sustained arrhythmia. The adaptive methods adjust persistence criteria used to analyze an arrhythmia prior to initiating a charging sequence to deliver therapy.
摘要翻译：用于在患者经历不持续性心律失常之后启动用于治疗递送的可植入医疗装置的大功率电容器的充电的自适应方法。适应性方法调整持续性标准，用于在启动充电序列之前分析心律失常以提供治疗。

87. 发明授权

US07477935B2 Method and apparatus for beat alignment and comparison 有权
标题翻译：拍子对准和比较的方法和装置
公开(公告)号：US07477935B2
公开(公告)日：2009-01-13
申请号：US10999274
申请日：2004-11-29
申请人： Surekha Palreddy , Jay A. Warren , Alan H. Ostroff
发明人： Surekha Palreddy , Jay A. Warren , Alan H. Ostroff
IPC分类号： A61B5/0468
CPC分类号： A61B5/04525 , A61B5/0464 , A61N1/3622 , A61N1/3956 , Y10S128/92
摘要： Methods of using a template having a template data set and template parameters to provide improved alignment of captured cardiac signal data to a stored template. More particularly, in an illustrative method, a captured cardiac signal is first configured using template parameters for a stored template. Then, once configured, the captured cardiac signal is then compared to the stored template. Other embodiments include implantable cardiac treatment devices including operational circuitry configured to perform the illustrative method. In a further embodiment, more than one stored templates may be used. Each template can have independently constructed parameters, such that a single captured cardiac signal may be configured using first parameters for comparison to a first template, and using second parameters for comparison to a second template.
摘要翻译：使用具有模板数据集和模板参数的模板的方法来提供捕获的心脏信号数据与存储的模板的改进对准。更具体地，在说明性方法中，首先使用用于存储的模板的模板参数来配置捕获的心脏信号。然后，一旦配置，捕获的心脏信号然后与存储的模板进行比较。其他实施例包括可植入心脏治疗装置，其包括被配置为执行说明性方法的操作电路。在另一实施例中，可以使用多于一个的存储的模板。每个模板可以具有独立构造的参数，使得可以使用用于与第一模板进行比较的第一参数以及使用用于与第二模板进行比较的第二参数来配置单个捕获的心脏信号。

88. 发明申请

US20080275521A1 Vector Switching in an Implantable Cardiac Stimulus System 有权
标题翻译：矢量切换植入式心脏刺激系统
公开(公告)号：US20080275521A1
公开(公告)日：2008-11-06
申请号：US12144462
申请日：2008-06-23
申请人： Jay A. Warren , Gust H. Bardy
发明人： Jay A. Warren , Gust H. Bardy
IPC分类号： A61N1/365
CPC分类号： A61N1/3925 , A61B5/04011 , A61B5/042 , A61B5/0424 , A61B5/7203 , A61B5/7207 , A61N1/3622 , A61N1/3706 , A61N1/3987
摘要： The implantable cardiac treatment system of the present invention is capable of choosing the most appropriate electrode vector to sense within a particular patient. In certain embodiments, the implantable cardiac treatment system determines the most appropriate electrode vector for continuous sensing based on which electrode vector results in the greatest signal amplitude, or some other useful metric such as signal-to-noise ratio (SNR). The electrode vector possessing the highest quality as measured using the metric is then set as the default electrode vector for sensing. Additionally, in certain embodiments of the present invention, a next alternative electrode vector is selected based on being generally orthogonal to the default electrode vector. In yet other embodiments of the present invention, the next alternative electrode vector is selected based on possessing the next highest quality metric after the default electrode vector. In some embodiments, if analysis of the default vector is ambiguous, the next alternative electrode vector is analyzed to reduce ambiguity.
摘要翻译：本发明的可植入心脏治疗系统能够选择最合适的电极载体以在特定患者体内感测。在某些实施例中，可植入心脏治疗系统基于哪个电极向量导致最大的信号幅度或诸如信噪比（SNR）的一些其他有用的度量来确定用于连续感测的最合适的电极向量。使用度量测量的具有最高质量的电极矢量然后被设置为用于感测的默认电极矢量。另外，在本发明的某些实施例中，基于大致正交于默认电极向量来选择下一个备选电极矢量。在本发明的其它实施例中，基于在默认电极向量之后拥有下一个最高质量度量来选择下一个备选电极矢量。在一些实施例中，如果默认矢量的分析是不明确的，则分析下一个替代电极矢量以减少模糊度。

89. 发明授权

US07444182B2 Method for discriminating between ventricular and supraventricular arrhythmias 有权
标题翻译：区分心室和室上性心律失常的方法
公开(公告)号：US07444182B2
公开(公告)日：2008-10-28
申请号：US11120258
申请日：2005-05-02
申请人： Alan H. Ostroff , Jay A. Warren , Gust H. Bardy
发明人： Alan H. Ostroff , Jay A. Warren , Gust H. Bardy
IPC分类号： A61N1/00
CPC分类号： A61N1/3956 , A61B5/0422 , A61B5/04525 , A61B5/0464 , A61B5/686 , A61N1/3925 , A61N1/3987
摘要： The present invention is direction toward a detection architecture for use in implantable cardiac rhythm devices. The detection architecture of the present invention provides methods and devices for discriminating between arrhythmais. Moreover, by exploiting the enhanced specificity in the origin of the identified arrhythmia, the detection architecture can better discriminate between rhythms appropriate for device therapy and those that are not.
摘要翻译：本发明是用于可植入心律装置的检测架构的方向。本发明的检测架构提供了用于区分心律失常的方法和装置。此外，通过利用识别的心律失常起源的增强的特异性，检测架构可以更好地区分适合于设备治疗的节律和不适合的治疗节律。

90. 发明授权

US07203539B2 Apparatus and method for energy management in atrial defibrillator 失效
标题翻译：心房除颤器能量管理装置及方法
公开(公告)号：US07203539B2
公开(公告)日：2007-04-10
申请号：US10794180
申请日：2004-03-05
申请人： Kurt Ware , Jay A. Warren
发明人： Kurt Ware , Jay A. Warren
IPC分类号： A61N1/00
CPC分类号： A61N1/3937 , A61N1/395
摘要： An apparatus and method for delivering electrical shock therapy in order to treat atrial tachyarrhythmias such as fibrillation in which the energy stored in a capacitor used to deliver a shock pulse is monitored and adjusted. A charging circuit is used to charge the capacitor from a supply voltage upon detection of an atrial arrhythmia, and a controller monitors sensed ventricular depolarizations until R-wave synchrony requirements are met so that an atrial shock pulse can be safely delivered. The controller also attempts to maintain the voltage of the capacitor at a specified voltage before delivery of the shock pulse by operation of the charging circuit.
摘要翻译：一种用于递送电击疗法以用于治疗心房性心律失常（例如颤动）的装置和方法，其中存储在用于递送冲击脉冲的电容器中的能量被监测和调整。一个充电电路用于在检测到房性心律失常时从电源电压充电，并且控制器监视感测到的心室去极化，直到满足R波同步要求，以便可以安全地传递心房休克脉冲。控制器还试图通过充电电路的操作在释放冲击脉冲之前将电容器的电压保持在指定的电压。

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