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81. 发明授权

US08848999B2 Method for increasing updating rate of reconstruction of a current three-dimensional image dataset of an object during a monitoring process and X-ray device 有权
标题翻译：在监视过程和X射线设备期间增加对象的当前三维图像数据集的重建更新速率的方法
公开(公告)号：US08848999B2
公开(公告)日：2014-09-30
申请号：US13094423
申请日：2011-04-26
申请人： Jan Boese , Frank Dennerlein
发明人： Jan Boese , Frank Dennerlein
IPC分类号： G06K9/00 , A61B6/00 , H01J35/06 , G06T11/00 , A61B19/00
CPC分类号： A61B6/4007 , A61B6/4021 , A61B6/5205 , A61B2090/3764 , G06T11/006 , G06T2211/412 , H01J35/065 , H01J2201/30469 , H01J2235/062 , H01J2235/068
摘要： A method for reconstruction of an actual three-dimensional image dataset of an object during a monitoring process is proposed. Two-dimensional X-ray projection images which correspond to a recording geometry are continuously recorded from different projection angles. The three-dimensional image dataset are reconstructed from a first number of these projection images, especially by a back projection method. The proportion of the oldest projection image contained in the current three-dimensional image dataset is removed from the three-dimensional image dataset and the proportion of the actual projection image is inserted in the three-dimensional image dataset after each recording of the actual projection image.
摘要翻译：提出了一种用于在监视过程中重建对象的实际三维图像数据集的方法。从不同的投影角度连续地记录与记录几何形状对应的二维X射线投影图像。从第一数量的这些投影图像，特别是通过反投影方法重构三维图像数据集。将包含在当前三维图像数据集中的最旧的投影图像的比例从三维图像数据集中去除，并且在每次记录实际投影图像之后将实际投影图像的比例插入到三维图像数据集中。

82. 发明授权

US08494245B2 System and method for guiding transcatheter aortic valve implantations based on interventional C-Arm CT imaging 有权
标题翻译：基于介入性C臂CT成像指导经导管主动脉瓣植入的系统和方法
公开(公告)号：US08494245B2
公开(公告)日：2013-07-23
申请号：US12945045
申请日：2010-11-12
申请人： Rui Liao , Yefeng Zheng , Matthias John , Alois Nöttling , Jan Boese , Uwe Kirschstein
发明人： Rui Liao , Yefeng Zheng , Matthias John , Alois Nöttling , Jan Boese , Uwe Kirschstein
IPC分类号： G06K9/00
CPC分类号： G06T19/00 , A61B6/032 , A61B6/4441 , A61B6/481 , A61B6/487 , A61B6/503 , A61B6/504 , A61B6/5235 , A61B6/54 , G06K2209/051 , G06T7/12 , G06T7/149 , G06T2207/10081 , G06T2207/20124 , G06T2207/30101 , G06T2219/028
摘要： A method for guiding transcatheter aortic valve implantations includes receiving an interventional 3D image of an aortic root reconstructed from a sequence of 2D images acquired from a C-arm computed tomography (CT) system being rotated about a patient through a predetermined number of degrees, segmenting the aortic root and detecting aortic root landmarks in the 3D image, where the aortic root landmarks include three lowest points of aortic root cusps, two coronary artery ostia, and three commissures points where the cusps meet, cropping an area inside the segmented aortic root out of the 3D volume for volume rendering, centering the 3D image on an intersection of two orthogonal planes, each containing the two detected coronary ostia, that are orthogonal to a plane spanned by three lowest points of the aortic root cusps, and volume rendering the 3D cropped aortic root image together with the detected landmarks onto a 2D image.
摘要翻译：用于引导经导管主动脉瓣植入的方法包括接收从从围绕患者旋转预定数量度的C臂计算机断层摄影（CT）系统获取的2D图像序列重建的主动脉根部的介入3D图像，分割主动脉根部并检测主动脉根部地标，其中主动脉根部地标包括主动脉根尖三个最低点，两个冠状动脉口和三个连接点，其中尖峰相遇，切除分段主动脉根部内的区域的体积渲染的3D体积，将3D图像定位在两个正交平面的交点上，每个正交平面包含两个检测到的冠状动脉，与主动脉根尖的三个最低点跨越的平面垂直，并且体积渲染3D 将主动脉根部图像与检测到的标记一起裁剪到2D图像上。

83. 发明授权

US08488737B2 Medical X-ray imaging system 有权
标题翻译：医用X射线成像系统
公开(公告)号：US08488737B2
公开(公告)日：2013-07-16
申请号：US12967297
申请日：2010-12-14
申请人： Jan Boese , Jens Fürst , Michael Maschke , Frank Sprenger
发明人： Jan Boese , Jens Fürst , Michael Maschke , Frank Sprenger
IPC分类号： G01N23/04 , H01J35/02
CPC分类号： A61B6/4233 , A61B6/4021 , A61B6/4441 , H01J2235/062
摘要： In order to achieve improved image quality in X-ray photographs, a medical X-ray imaging system, comprising a flat, planar X-ray source having a surface with X-ray focal points arranged adjacent to one another and an X-ray detector with a sensor surface, is provided. The X-ray source has a plurality of field emission guns with at least one field emission cathode and the surface with focal points of the X-ray source is larger in size than the sensor surface of the X-ray detector.
摘要翻译：为了在X射线照片中实现改善的图像质量，医疗X射线成像系统包括平面X射线源，其具有彼此相邻布置的具有X射线焦点的表面和X射线检测器提供传感器表面。 X射线源具有多个具有至少一个场发射阴极的场发射枪，并且具有X射线源的焦点的表面的尺寸大于X射线探测器的传感器表面。

84. 发明申请

US20130004040A1 LEFT VENTRICLE EPICARDIUM ESTIMATION IN MEDICAL DIAGNOSTIC IMAGING 有权
标题翻译：医学诊断成像中的左心室环境评估
公开(公告)号：US20130004040A1
公开(公告)日：2013-01-03
申请号：US13533234
申请日：2012-06-26
申请人： Mingqing Chen , Yefeng Zheng , Kerstin Mueller , Christopher Rohkohl , Günter Lauritsch , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
发明人： Mingqing Chen , Yefeng Zheng , Kerstin Mueller , Christopher Rohkohl , Günter Lauritsch , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
IPC分类号： G06K9/68
CPC分类号： G06T7/251 , G06T11/005 , G06T2207/10081 , G06T2207/30048 , G06T2211/412
摘要： The left ventricle epicardium is estimated in medical diagnostic imaging. C-arm x-ray data is used to detect an endocardium at different phases. The detected endocardium at the different phases is compared to sample endocardiums at different phases. The sample endocardiums have corresponding sample epicadriums. The transformation between the most similar sample endocardium or endocardiums over time and the detected endocardium over time is applied to the corresponding sample epicardium or epicardiums. The transformed sample epicardium over time is the estimated epicardium over time for the C-arm x-ray data.
摘要翻译：估计左心室心外膜在医学诊断成像中。 C臂X射线数据用于检测不同阶段的心内膜。将检测到的不同阶段的心内膜与不同阶段的样品心内膜进行比较。样品心内膜具有相应的样品epicadrium。随着时间的推移，最相似的样品心内膜或心内膜与随时间的检测到的心内膜之间的转化被应用于相应的样品心外膜或心外膜。随着时间的推移，转化的样品心外膜随着时间的推移，C-arm x射线数据的估计心外膜。

85. 发明申请

US20120238866A1 Method and System for Catheter Tracking in Fluoroscopic Images Using Adaptive Discriminant Learning and Measurement Fusion 有权
标题翻译：使用自适应判别学习和测量融合的荧光图像中导管跟踪的方法和系统
公开(公告)号：US20120238866A1
公开(公告)日：2012-09-20
申请号：US13412882
申请日：2012-03-06
申请人： Peng Wang , Yefeng Zheng , Matthias John , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
发明人： Peng Wang , Yefeng Zheng , Matthias John , Jan Boese , Gareth Funka-Lea , Dorin Comaniciu
IPC分类号： A61B6/00 , A61M25/00
CPC分类号： A61B6/487 , A61B6/12 , A61B6/503 , G06T7/246 , G06T2207/10016 , G06T2207/10064 , G06T2207/20076 , G06T2207/20081 , G06T2207/30021 , G06T2207/30048
摘要： A method and system for adaptive discriminant learning and measurement fusion for image based catheter tracking is disclosed. An adaptive discriminant model is trained online based on a tracked object, such as a pigtail catheter tip, in at least one previous frame of a fluoroscopic image sequence. The object is tracked in the current frame of the fluoroscopic image sequence based at least on the adaptive discriminant model trained online. The object may be tracked in the current frame based on a fusion of three types of measurement models including the adaptive discriminant model trained online, an object detection model trained offline, and an online appearance model.
摘要翻译：公开了一种用于基于图像的导管跟踪的自适应判别学习和测量融合的方法和系统。在荧光镜像图像序列的至少一个先前帧中，基于跟踪对象（例如尾纤导管尖端）在线训练自适应判别模型。至少基于在线训练的自适应判别模型，在透视图像序列的当前帧中跟踪对象。基于三种类型的测量模型的融合，可以在当前帧中跟踪对象，包括在线训练的自适应判别模型，离线训练的对象检测模型和在线外观模型。

86. 发明授权

US08244064B2 Method for registering and merging medical image data 有权
标题翻译：用于注册和合并医学图像数据的方法
公开(公告)号：US08244064B2
公开(公告)日：2012-08-14
申请号：US11043464
申请日：2005-01-26
申请人： Jan Boese , Benno Heigl , Norbert Rahn
发明人： Jan Boese , Benno Heigl , Norbert Rahn
IPC分类号： G06K9/32
CPC分类号： A61B5/1127 , A61B5/721 , A61B6/032 , A61B6/527 , A61B6/583 , G06F19/00 , G06T7/30 , G06T2207/30004
摘要： The present invention relates to a method for the registration and superimposition of image data when taking serial radiographs in medical imaging, wherein a plurality of image data sets for a region of a patient (17) that is being investigated are constructed at time intervals using an imaging system (1) and are referenced with a first image data set for the region that is being investigated that was constructed previously using said imaging system (1). In the above method, a location system (2) is used during the production of serial radiographs constantly, or at least at a respective proximity in time to the construction of individual data sets, to determine a current spatial position of the region being investigated in a reference system that is firmly connected to the imaging system (1), whereby in the construction of the first image data set, a first spatial position of the region that is being investigated is recorded. In the construction of some or all further image data sets, the respective current spatial position of the region that is being investigated is determined and an image content of each first image data set is geometrically adapted on the basis of the difference between the first and the current spatial position, such that compensation is made for a different spatial position of the region that is being investigated. The geometrically adapted first image data set or an image data set derived therefrom, or an image data set that is positionally connected thereto by registration is then displayed superimposed with the respective further image data set.
摘要翻译：本发明涉及一种用于在医学成像中拍摄连续摄影时对图像数据进行配准和叠加的方法，其中，对于正在研究的患者（17）的区域的多个图像数据组以时间间隔使用成像系统（1），并且被使用先前使用所述成像系统（1）构造的正被研究的区域的第一图像数据集参考。在上述方法中，在串行X射线照相制作期间，或者至少在各个相邻的时间内接近单个数据集的构造，使用定位系统（2）来确定正被调查的区域的当前空间位置牢固地连接到成像系统（1）的参考系统，由此在第一图像数据组的构造中记录正被调查的区域的第一空间位置。在构建一些或所有其他图像数据集时，确定正在研究的区域的相应当前空间位置，并且基于第一和第二图像数据组之间的差异来对每个第一图像数据集的图像内容进行几何适配。当前的空间位置，使得对正被调查的区域的不同空间位置进行补偿。然后，将几何适应的第一图像数据集或从其导出的图像数据集或通过登记与其位置连接的图像数据组叠加显示相应的另外的图像数据集。

87. 发明授权

US08218717B2 Reconstruction of 3D image datasets from x-ray and cone-beam data 有权
标题翻译：从X射线和锥束数据重建3D图像数据集
公开(公告)号：US08218717B2
公开(公告)日：2012-07-10
申请号：US12902237
申请日：2010-10-12
申请人： Jan Boese , Frank Dennerlein , Holger Kunze
发明人： Jan Boese , Frank Dennerlein , Holger Kunze
IPC分类号： A61B6/00
CPC分类号： G06T11/006 , A61B6/027
摘要： A method for producing a 3D image dataset of an object with an imaging system having an x-ray source and an x-ray detector is provided. A series of two-dimensional arrays of cone beam data from the detector is acquired while the source moves along a substantially planar trajectory around the object. The trajectory is described by a series of source points serially numbered by a counter parameter. The cone beam data is differentiated with respect to the counter parameter at a fixed ray direction to produce a derivative of the cone beam data. The derivative is filtered with a Hilbert-like filter to produce filtered cone beam data. The acquired or the filtered cone beam data is multiplied with a redundancy weighting function. The cone beam data is back-projected to reconstruct a 3D image dataset.
摘要翻译：提供了一种使用具有X射线源和X射线检测器的成像系统来生成物体的3D图像数据集的方法。来自检测器的一系列锥形束数据的二维阵列被获取，同时源沿着围绕物体的基本上平面的轨迹移动。轨迹由一系列通过计数器参数串行编号的源点描述。锥形束数据在固定的射线方向上相对于计数器参数微分，以产生锥形束数据的导数。用希尔伯特滤波器滤波导数，以产生滤波的锥束数据。所获取的或经滤波的锥束数据与冗余加权函数相乘。锥形束数据被反投影以重建3D图像数据集。

88. 发明申请

US20120136243A1 METHOD FOR CALCULATING PERFUSION DATA 审中-公开
标题翻译：计算灌注数据的方法
公开(公告)号：US20120136243A1
公开(公告)日：2012-05-31
申请号：US13302170
申请日：2011-11-22
申请人： Jan Boese , Andreas Fieselmann , Klaus Klingenbeck , Markus Kowarschik
发明人： Jan Boese , Andreas Fieselmann , Klaus Klingenbeck , Markus Kowarschik
IPC分类号： A61B5/05
CPC分类号： A61B6/481 , A61B5/0275 , A61B6/4458 , A61B6/4464 , A61B6/50 , A61B6/501 , A61B6/504 , A61B6/507
摘要： A method for calculating perfusion data, such as blood volume or blood flow from 2-D angiography data or DSA sequences, is proposed. An angiography scene is recorded using specific acquisition parameters to generate the 2-D angiography data or DSA sequences with administration of contrast agent based on a multiplicity of individual angiography images. A region of interest is defined suitable for comparison purposes. The volume segments are defined by the region of interest. The time/contrast curve is determined in the volume segments. Perfusion data for calculating the relative perfusion data is ascertained. The perfusion data is compared and the relative perfusion data is calculated. The calculated relative perfusion data is not specified in terms of absolute physical quantities, but is provided simply as ratios, such as left/right or before/after.
摘要翻译：提出了一种从二维血管造影数据或DSA序列计算灌注数据如血容量或血流量的方法。使用特定采集参数记录血管造影场景，以基于多个单独的血管造影图像施用造影剂来产生2-D血管造影数据或DSA序列。感兴趣的区域被定义为适合于比较目的。音量段由感兴趣的区域定义。时间/对比度曲线在音量段中确定。确定用于计算相对灌注数据的灌注数据。比较灌注数据，计算相对灌注数据。计算的相对灌注数据不是以绝对物理量表示，而是简单地作为比例提供，例如左/右或之前/之后。

89. 发明申请

US20110274335A1 Method for recording and reconstructing a three-dimensional image dataset and x-ray apparatus 有权
标题翻译：用于记录和重建三维图像数据集和X射线装置的方法
公开(公告)号：US20110274335A1
公开(公告)日：2011-11-10
申请号：US13101208
申请日：2011-05-05
申请人： Jan Boese , Anja Borsdorf , Frank Dennerlein , Holger Kunze
发明人： Jan Boese , Anja Borsdorf , Frank Dennerlein , Holger Kunze
IPC分类号： G06K9/00 , A61B6/03
CPC分类号： G06T11/005 , A61B6/4441
摘要： A method for recording and reconstructing a three-dimensional image dataset is proposed. A plurality of projection images are acquired under different recording geometries in relation to an object to be recorded by an X-ray apparatus, in particular a C-arm X-ray apparatus. At least two projection images are recorded for at least one recording geometry, in particular for every recording geometry. The three-dimensional image dataset is reconstructed from the project images.
摘要翻译：提出了一种用于记录和重建三维图像数据集的方法。相对于由X射线装置，特别是C臂X射线装置记录的物体，在不同的记录几何形状下获取多个投影图像。对于至少一个记录几何形状记录至少两个投影图像，特别是对于每个记录几何形状。从项目图像重建三维图像数据集。

90. 发明授权

US08032203B2 Method and medical imaging system for acquisition of image data by using a pacemaker signal to control the imaging system 有权
标题翻译：方法和医学成像系统，用于通过使用起搏器信号来获取图像数据来控制成像系统
公开(公告)号：US08032203B2
公开(公告)日：2011-10-04
申请号：US11900834
申请日：2007-09-13
申请人： Jan Boese , Andreas Meyer , Norbert Rahn
发明人： Jan Boese , Andreas Meyer , Norbert Rahn
IPC分类号： A61B6/00 , A61N1/05
CPC分类号： A61B6/541 , A61B5/0402 , A61B6/4441
摘要： The invention relates to a method and a medical imaging system for acquisition of image data of the heart using a medical imaging procedure during an intervention on the heart, while the heart is stimulated by a pacing signal from an external heart pacemaker, the acquisition and/or reconstruction of the image data being controlled, in particular triggered, by the pacing signal.
摘要翻译：本发明涉及一种用于在心脏介入期间使用医学成像程序获取心脏的图像数据的方法和医学成像系统，同时心脏由来自外部心脏起搏器的起搏信号刺激，采集和/ 或通过起搏信号来重构被特别触发的图像数据。

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