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81. 发明申请

US20100063107A1 HYDROXY METHYL PHENYL PYRAZOLYL UREA COMPOUNDS USEFULL IN THE TREATMENT OF CANCER 有权
标题翻译：用于治疗癌症的羟基甲基苯基吡唑啉酮化合物
公开(公告)号：US20100063107A1
公开(公告)日：2010-03-11
申请号：US12520609
申请日：2007-12-20
申请人： Roger Smith , Dhanapalan Nagarathnam
发明人： Roger Smith , Dhanapalan Nagarathnam
IPC分类号： A61K31/4439 , C07D401/12
CPC分类号： C07D401/12
摘要： The compound 4-{4-[({3-tert-Butyl-1-[3-(hydroxymethyl)phenyl]-1H-pyrazol-5-yl}carbamoyl)amino]-3-fluorophenoxy}-N-methylpyridine-2-carboxamide and alternative forms thereof (e.g., salts, solvates, hydrates, prodrugs, polymorphs and metabolites); pharmaceutical compositions which contain them; and methods for treating cancer using them.
摘要翻译：化合物4- {4 - [（{3-叔丁基-1- [3-（羟基甲基）苯基] -1H-吡唑-5-基}氨基甲酰基）氨基] -3-氟苯氧基} -N-甲基吡啶-2 （例如盐，溶剂合物，水合物，前药，多晶型物和代谢物）; 含有它们的药物组合物; 以及使用它们治疗癌症的方法。

82. 发明申请

US20090270468A1 Preparation and use of aryl alkyl acid derivatives for the treatment of obesity 失效
标题翻译：芳基烷基酸衍生物的制备和用途用于治疗肥胖症
公开(公告)号：US20090270468A1
公开(公告)日：2009-10-29
申请号：US12231878
申请日：2008-09-05
申请人： Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Minghao Zhang , Lei Zhu
发明人： Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Minghao Zhang , Lei Zhu
IPC分类号： A61K31/428 , C07D277/82 , A61K31/423 , C07D263/58 , C07D235/30 , A61K31/4184 , A61P3/04
CPC分类号： C07D263/58 , C07D235/30 , C07D263/60 , C07D277/42 , C07D277/58 , C07D277/82 , C07D405/12 , C07D413/12 , C07D417/12
摘要： This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
摘要翻译：本发明涉及某些芳基烷基酸化合物，组合物和治疗或预防肥胖症和相关疾病的方法。

83. 发明授权

US07599062B2 Local non-perturbative remote sensing devices and method for conducting diagnostic measurements of magnetic and electric fields of optically active mediums 有权
公开(公告)号：US07599062B2
公开(公告)日：2009-10-06
申请号：US11900948
申请日：2007-09-14
申请人： Roger Smith
发明人： Roger Smith
IPC分类号： G01J4/00
CPC分类号： G01J4/04 , G01N21/21 , G01N2021/1793
摘要： Embodiments of the present invention are directed to pulsed polarimeters for conducting remote, non-perturbative diagnostic measurements of inducing fields of a medium demonstrating induced optical activity. In one aspect, a pulse polarimeter includes a light source emitting a polarized light pulse having sufficiently narrow spatial extent at a prescribed wavelength and a light gathering optical system including a light gathering optic having an optic axis directed toward the medium and positioned to collect and collimate a predetermined solid angle of an emission from the medium into a collimated emission beam, while preserving the polarization state of the emission. The pulse polarimeter includes a directional coupler that makes coincident the propagation direction of the polarized light pulse with the optic axis and a polarization detection system for measuring the intensity and determining the polarization state of the collimated emission beam continuously in time as the polarized light pulse transits the medium.

84. 发明申请

US20090197795A1 PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY 审中-公开
标题翻译：用于治疗糖尿病的芳基酸衍生物的制备和使用
公开(公告)号：US20090197795A1
公开(公告)日：2009-08-06
申请号：US12185813
申请日：2008-08-04
申请人： Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
发明人： Roger Smith , Ann-Marie Campbell , Philip Coish , Miao Dai , Susan Jenkins , Derek Lowe , Stephen O'Connor , Ning Su , Gan Wang , Mingbao Zhang , Lei Zhu
IPC分类号： A61K31/428 , A61K38/28 , A61P3/10 , A61K38/22 , A61P3/04 , A61K31/423 , A61K31/426 , A61K31/4184 , C07D277/82 , C07D235/30 , C07D277/38 , C07D263/58
CPC分类号： C07D263/58 , C07D235/30 , C07D263/60 , C07D277/42 , C07D277/58 , C07D277/82 , C07D405/12 , C07D413/12 , C07D417/12
摘要： This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
摘要翻译：本发明涉及某些芳基烷基酸化合物，组合物和治疗或预防肥胖症和相关疾病的方法。

85. 发明申请

US20080047848A1 SNAP AND LIFT PACKAGE FOR CONTACT LENS 审中-公开
标题翻译：用于接触镜头的SNAP和LIFT包装
公开(公告)号：US20080047848A1
公开(公告)日：2008-02-28
申请号：US11561707
申请日：2006-11-20
申请人： Michael Tokarski , James Peck , Edward Dzwill , George Brock , James Davis , Roger Smith , Michael Ulrich
发明人： Michael Tokarski , James Peck , Edward Dzwill , George Brock , James Davis , Roger Smith , Michael Ulrich
IPC分类号： A45C11/04
CPC分类号： B65D75/366 , A45C11/005 , B65D2575/367 , B65D2585/545
摘要： A contact lens package includes a first housing member and a second housing member pivotably connected to each other. The package also includes a holding mechanism for holding a contact lens and a receiving mechanism for receiving contact lens solution. When the housing members are in a substantially co-planar orientation, the holding mechanism is positioned within the receiving mechanism. When the housing members are in a non-planar orientation, the holding mechanism is removed from the receiving mechanism such that the holding mechanism is pivotable from a closed position, in which the contact lens held in the holding mechanism is inaccessible to a user, toward an open position, in which the contact lens held in the holding mechanism is accessible to the user.
摘要翻译：隐形眼镜包装包括第一壳体构件和可枢转地彼此连接的第二壳体构件。该包装还包括用于保持隐形眼镜的保持机构和用于接收隐形眼镜溶液的接收机构。当壳体构件处于基本上共平面的方向时，保持机构位于接收机构内。当壳体构件处于非平面取向时，保持机构从接收机构移除，使得保持机构可从闭合位置枢转，其中保持在保持机构中的隐形眼镜不能被用户接近保持在保持机构中的隐形眼镜可以被用户接近的打开位置。

86. 发明申请

US20070265298A1 Preparation and Use of Biphenyl-4-Yl-Carbonylamino Acid Derivatives for the Treatment of Obesity 失效
标题翻译：联苯-4-基羰基氨基酸衍生物用于治疗肥胖症的制备与应用
公开(公告)号：US20070265298A1
公开(公告)日：2007-11-15
申请号：US11665317
申请日：2005-10-14
申请人： Roger Smith , Stephen O'Connor , Philip Coish , Derek Lowe , Roger Clark , Jeffrey Stebbins , Ann-Marie Campbell , Christiana Akuche , Tatiana Shelekhin
发明人： Roger Smith , Stephen O'Connor , Philip Coish , Derek Lowe , Roger Clark , Jeffrey Stebbins , Ann-Marie Campbell , Christiana Akuche , Tatiana Shelekhin
IPC分类号： A61K31/435 , A61K31/421 , A61K31/44 , C07D277/00 , C07D471/02 , A61P7/12 , A61K31/426
CPC分类号： C07D235/30 , C07D263/58 , C07D277/82 , C07D513/04
摘要： This invention relates to certain biphenyl-4-yl carbonylamino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.
摘要翻译：本发明涉及某些联苯-4-基羰基氨基酸化合物，组合物和治疗或预防肥胖症及相关疾病的方法。

87. 发明申请

US20070261973A1 Container with molded digital disk holder 审中-公开
标题翻译：容器带有模制数字磁盘支架
公开(公告)号：US20070261973A1
公开(公告)日：2007-11-15
申请号：US11826967
申请日：2007-07-19
申请人： Robert Harman , John Safian , Roger Smith
发明人： Robert Harman , John Safian , Roger Smith
IPC分类号： B65D23/12
CPC分类号： G11B23/0021 , G11B33/0427
摘要： A container with an interior and a neck finish has a recessed pocket on an exterior side of a sidewall for snap fitting a digital disk thereon. Opposing flanges at the periphery of the pocket snap fit the disk in place in a generally vertical orientation.
摘要翻译：具有内部和颈部整理的容器在侧壁的外侧上具有凹入的凹槽，用于在其上卡入数字盘。口袋周边处的相对的凸缘以大致垂直的方向安装在适当位置。

88. 发明申请

US20070130244A1 Multilayer correlation profiling engines 有权
标题翻译：多层相关分析引擎
公开(公告)号：US20070130244A1
公开(公告)日：2007-06-07
申请号：US11634223
申请日：2006-12-06
申请人： Scott Swanburg , Mark Wuthnow , James Ryan , Herman Chien , Roger Smith
发明人： Scott Swanburg , Mark Wuthnow , James Ryan , Herman Chien , Roger Smith
IPC分类号： G06F15/16
CPC分类号： G06Q30/016 , H04L67/306
摘要： A profiling engine is disclosed. The profiling engine collects information from a variety of sources in real time and stores the information in a profile. The profile may have a number of layers, each layer having a number of categories. The profile is made available for use by applications and services.
摘要翻译：公开了一种轮廓引擎。分析引擎实时收集来自各种来源的信息，并将信息存储在配置文件中。轮廓可以具有多个层，每个层具有多个类别。该配置文件可供应用程序和服务使用。

89. 发明申请

US20070124957A1 Air condition shoes 审中-公开
标题翻译：空调鞋
公开(公告)号：US20070124957A1
公开(公告)日：2007-06-07
申请号：US11294194
申请日：2005-12-06
申请人： Roger Smith
发明人： Roger Smith
IPC分类号： A43B7/06
CPC分类号： A43B7/081 , A43B13/203
摘要： The invention is directed to the part of the shoe where the bottom of the foot makes contact. This part consists of a resilient material such as foam rubber. This foam is incased with an air tight plastic material, with one way valves. There will be intake valves at the heel and exhaust vents at the toe area. When pressure is applied by the foot to the foam filled bladder, air will be forced out of the one-way valves at the front of the shoe. Then when a step is taken, pressure is removed, and the foam will draw air in the one way valves at the rear of the shoe. With each step and release the air will be circulated.
摘要翻译：本发明涉及鞋的底部接触的鞋部分。该部分由弹性材料如泡沫橡胶组成。这种泡沫是用气密的塑料材料，单向阀。脚跟处有进气阀，脚趾区域有排气口。当脚施加到泡沫填充的气囊上时，空气将被迫从鞋的前部的单向阀排出。然后当采取步骤时，去除压力，并且泡沫将以鞋的后部的单向阀吸入空气。随着每个步骤和释放空气将流通。

90. 发明申请

US20070089998A1 Contact lens packages 有权
标题翻译：隐形眼镜包装
公开(公告)号：US20070089998A1
公开(公告)日：2007-04-26
申请号：US11255144
申请日：2005-10-20
申请人： Michael Tokarski , James Peck , Edward Dzwill , George Brock , Roger Smith , Michael Schulte , Michael Ulrich
发明人： Michael Tokarski , James Peck , Edward Dzwill , George Brock , Roger Smith , Michael Schulte , Michael Ulrich
IPC分类号： A45C11/04
CPC分类号： A45C11/005 , B65D2585/545
摘要： The invention provides contact lens packages in which removal of the lens is facilitated by providing a means for elevating the lens when the package is opened.
摘要翻译：本发明提供了隐形眼镜包装，其中通过提供当包装打开时提升透镜的装置来促进透镜的移除。

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