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81. 发明专利

NZ566494A Adhesive preparation containing bisoprolol 未知
公开(公告)号：NZ566494A
公开(公告)日：2010-10-29
申请号：NZ56649406
申请日：2006-09-07
申请人： NITTO DENKO CORP , TOA EIYO LTD
发明人： IWAO YOSHIHIRO , OOKUBO KATSUYUKI , OKADA KATSUHIRO , MINAMI KUNIHIRO , YUASA SHUICHIRO
IPC分类号： A61K31/138 , A61K9/70 , A61K47/10 , A61K47/14 , A61K47/32 , A61P9/06 , A61P9/10 , A61P9/12
摘要： Disclosed is an adhesive pharmaceutical preparation containing bisoprolol, which comprises a support and an adhesive layer on one side of the support, wherein the adhesive layer contains bisoprolol, polyisobutylene, a tackifier, and an organic liquid ingredient compatible with polyisobutylene and the tackifier selected from a fatty acid alkyl ester, a long-chain alcohol selected from saturated or unsaturated alcohols having from 12 to 28 carbon atoms, or a combination thereof; and wherein the content of bisoprolol per the total weight of the adhesive layer is 0.5 to 5% by weight.

82. 发明专利

CA2617455A1 PATCH PACKAGE STRUCTURE 未知
公开(公告)号：CA2617455A1
公开(公告)日：2008-07-11
申请号：CA2617455
申请日：2008-01-09
申请人： NITTO DENKO CORP
发明人： MATSUOKA KENSUKE , IWAO YOSHIHIRO , OKADA KATSUHIRO
IPC分类号： A61M37/00 , B65D75/32 , B65D85/00
摘要： The present invention provides a patch package structure, which includes: a package including a first sheet material which is planar and a second sheet material which has been molded, the first and second sheet materials being sealed together in peripheral parts thereof, and a patch disposed in the package, in which the patch contains a backing, a pressure-sensitive adhesive layer laminated on at least one side of the backing, and a release liner which protects a pressure-sensitive adhesive surface of the pressure-sensitive adhesive layer; the second sheet material has been molded so as to have a protrudent part in at least a substantially central area thereof, the protrudent part having a planar outer shape larger than a planar outer shape of the release liner and having at least one recessed part; d is not smaller than T, in which d is the minimum gap distance between the inner surface of the first sheet material and the inner surface of the second sheet material at the recessed part and T is a thickness of the patch; and, at the boundary between the sealed part where the first and second sheet materials are sealed together and an unsealed part, the outer surface of the second sheet material rises at an obtuse angle.

83. 发明专利

AU2003204326B2 Pressure Sensitive Adhesive Sheet 未知
公开(公告)号：AU2003204326B2
公开(公告)日：2007-05-10
申请号：AU2003204326
申请日：2003-05-23
申请人： NITTO DENKO CORP
发明人： OKADA KATSUHIRO , MURAKAMI YOSHIHIDE
IPC分类号： A61L15/58 , C08G18/48 , C09J7/02 , C09J133/08
摘要： A pressure sensitive adhesive sheet which has a moderate adhesive strength, does hardly add physical stimuli to the adherend at the time of peeling and also has such a good processing suitability that the support does not generate swelling deformation by transfer of a liquid component from the adhesive layer. The pressure sensitive adhesive sheet has an adhesive layer formed from a resin composition comprising an acrylic acid ester polymer, a carboxylic acid ester having 16 or more carbon atoms which is compatible with the acrylic acid ester polymer and is liquid or paste at ordinary temperature, and a crosslinking component, and a film supporting the adhesive layer, comprising a polyether urethane resin obtained by allowing a polyol component to react with a polyisocyanate component, wherein the polyol component constituting the urethane resin contains at least one kind of polyether polyol having a polyoxyalkylene backbone represented by a specified repeating unit.

84. 发明专利

AU2006288260A1 Adhesive preparation containing bisoprolol 未知
公开(公告)号：AU2006288260A1
公开(公告)日：2007-03-15
申请号：AU2006288260
申请日：2006-09-07
申请人： NITTO DENKO CORP , TOA EIYO LTD
发明人： IWAO YOSHIHIRO , OHKUBO KATSUYUKI , OKADA KATSUHIRO , MINAMI KUNIHIRO , YUASA SHUICHIRO
IPC分类号： A61K31/138 , A61K9/70 , A61K47/10 , A61K47/14 , A61K47/32 , A61P9/06 , A61P9/10 , A61P9/12
摘要： An adhesive pharmaceutical preparation which has a less irritation to the skin surface, keeps excellent stability of bisoprolol in the preparation, and allows continuous administration of a pharmacologically effective amount of bisoprolol into the living body, is provided. The adhesive preparation 10 comprises a support 1, an adhesive layer 2 laminated on one surface of the support 1. The adhesive layer 2 is characterized by containing bisoprolol, polyisobutylene, tackifier, and an organic liquid ingredient compatible to polyisobutylene and tackifier. Thus, an adhesive pharmaceutical preparation which has a good adhesiveness with less irritation to the skin and which gives almost no pain at peel-off or removal from the skin surface with leaving almost no paste, can be provided. In addition, bisoprolol is very stably maintained in the preparation and a pharmacologically effective amount of bisprolol can be administered continuously into the living body through the skin surface.

85. 发明专利

DK1184039T3 未知
公开(公告)号：DK1184039T3
公开(公告)日：2005-11-07
申请号：DK01120944
申请日：2001-08-31
申请人： NITTO DENKO CORP
发明人： MURAKAMI YOSHIHIDE , OKADA KATSUHIRO
IPC分类号： C09J133/08 , A61L15/58 , C08G18/62 , C09J175/04 , C09J133/04 , C09J7/02 , C09J133/06
摘要： The present invention provides an adhesive tape or sheet for application to skin, which is made of an adhesive composition containing an acrylic copolymer having a specific composition and a specific carboxylic acid ester, wherein the acrylic copolymer has a gel fraction adjusted to a specific range. The adhesive tape or sheet for skin of the present invention can be used for first aid adhesive plasters, surgical tapes, large adhesive plasters with a pad, dressing materials and the like.

86. 发明专利

DE60300633T2 未知
公开(公告)号：DE60300633T2
公开(公告)日：2005-10-06
申请号：DE60300633
申请日：2003-05-28
申请人： NITTO DENKO CORP
发明人： MURAKAMI YOSHIHIDE , OKADA KATSUHIRO
IPC分类号： A61L15/58 , C08G18/48 , C09J7/02 , C09J133/08 , C09J11/06 , A61L24/04
摘要： A pressure sensitive adhesive sheet which has a moderate adhesive strength, does hardly add physical stimuli to the adherend at the time of peeling and also has such a good processing suitability that the support does not generate swelling deformation by transfer of a liquid component from the adhesive layer. The pressure sensitive adhesive sheet has an adhesive layer formed from a resin composition comprising an acrylic acid ester polymer, a carboxylic acid ester having 16 or more carbon atoms which is compatible with the acrylic acid ester polymer and is liquid or paste at ordinary temperature, and a crosslinking component, and a film supporting the adhesive layer, comprising a polyether urethane resin obtained by allowing a polyol component to react with a polyisocyanate component, wherein the polyol component constituting the urethane resin contains at least one kind of polyether polyol having a polyoxyalkylene backbone represented by a specified repeating unit.

87. 发明专利

ES2238650T3 HOJA ADHESIVA SENSIBLE A LA PRESION. 未知
公开(公告)号：ES2238650T3
公开(公告)日：2005-09-01
申请号：ES03012062
申请日：2003-05-28
申请人： NITTO DENKO CORP
发明人： MURAKAMI YOSHIHIDE , OKADA KATSUHIRO
IPC分类号： A61L15/58 , C08G18/48 , C09J7/02 , C09J133/08 , C09J11/06 , A61L24/04
摘要： Hoja adhesiva sensible a la presión que comprende: una capa adhesiva formada a partir de una composición de resina que comprende un polímero de éster de ácido acrílico, un éster de ácido carboxílico con 16 átomos de carbono o más, compatible con dicho polímero de éster de ácido acrílico y que, a temperatura ordinaria, es un líquido o una pasta, y un componente reticulante, y una película que soporta dicha capa adhesiva, que comprende una resina de poliéter-uretano obtenida haciendo reaccionar un componente poliol con un componente poliisocianato, en la que el componente poliol contiene por lo menos un tipo de poliéter-poliol que presenta un esqueleto de polioxialquileno cuya unidad de repetición está representada por la fórmula (1) siguiente: (en la que R representa H o un grupo alquilo).

88. 发明专利

AU2005200368A1 Film base material for adhesive skin patch and adhesive skin patch 未知
公开(公告)号：AU2005200368A1
公开(公告)日：2005-08-18
申请号：AU2005200368
申请日：2005-01-31
申请人： NITTO DENKO CORP
发明人： YOSHIKAWA TOSHIYUKI , SASAKI YASUYUKI , OKADA KATSUHIRO , SUZUKI SEISHI
IPC分类号： C08J5/18 , A61F13/00 , A61L15/26
摘要： To have acceptable moisture permeability and enable prevention of deformation due to swelling, the filmbasematerial for an adhesive skin patch includes an ether-based urethane resin obtained from at least one member selected from the group consisting of polyoxytetramethylene glycol, butanediol, polyethylene glycol, and polypropylene glycol as a diol component, and methylene diphenyl-diisocyanate as an isocyanate component. The film base material for an adhesive skin patch has a moisture permeability of preferably 800 to 4,000 g/m . 24hrs. The adhesive skin patch can be produced by forming a pressure-sensitive adhesive layer on one side of the film base material for an adhesive skin patch.

89. 发明专利

DE69918768T2 未知
公开(公告)号：DE69918768T2
公开(公告)日：2005-06-30
申请号：DE69918768
申请日：1999-10-18
申请人： NITTO DENKO CORP
发明人： MURAKAMI YOSHIHIDE , OKADA KATSUHIRO
IPC分类号： C08L75/08 , C09J7/02

90. 发明专利

AT295398T 未知
公开(公告)号：AT295398T
公开(公告)日：2005-05-15
申请号：AT03012062
申请日：2003-05-28
申请人： NITTO DENKO CORP
发明人： MURAKAMI YOSHIHIDE , OKADA KATSUHIRO
IPC分类号： A61L15/58 , C08G18/48 , C09J7/02 , C09J133/08 , C09J11/06 , A61L24/04
摘要： A pressure sensitive adhesive sheet which has a moderate adhesive strength, does hardly add physical stimuli to the adherend at the time of peeling and also has such a good processing suitability that the support does not generate swelling deformation by transfer of a liquid component from the adhesive layer. The pressure sensitive adhesive sheet has an adhesive layer formed from a resin composition comprising an acrylic acid ester polymer, a carboxylic acid ester having 16 or more carbon atoms which is compatible with the acrylic acid ester polymer and is liquid or paste at ordinary temperature, and a crosslinking component, and a film supporting the adhesive layer, comprising a polyether urethane resin obtained by allowing a polyol component to react with a polyisocyanate component, wherein the polyol component constituting the urethane resin contains at least one kind of polyether polyol having a polyoxyalkylene backbone represented by a specified repeating unit.

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