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81. 发明公开

EP2358196A1 KRYOSPEICHEREINRICHTUNG 有权
公开(公告)号：EP2358196A1
公开(公告)日：2011-08-24
申请号：EP09756254.0
申请日：2009-11-09
申请人： Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
发明人： ZIMMERMANN, Heiko , SCHÖN, Uwe , FUHR, Günter , LEUTHOLD, Dirk , BELKE, Marianne
IPC分类号： A01N1/02 , G01N1/42
CPC分类号： A01N1/0252 , F25B2700/04 , F25D3/102 , F25D3/11 , F25D29/001 , F25D2600/02 , F25D2700/12 , F25D2700/16 , G01N1/42 , G01N2035/00435
摘要： The invention relates to a cryogenic storage device and to a method for operating a cryogenic storage device, particularly for cryogenic storage of biological samples, comprising a sample carrying device that is set up to accommodate samples, a cryogenic container that is set up to accommodate the sample carrying device, a container cooling device with which the cryogenic container can be cooled, an intermediate storage container that is set up for intermediate storage of the sample carrying device, a transport device with which the sample carrying device can be moved between the cryogenic container and the intermediate storage container and a sensor device with which at least one operating parameter of the cryogenic storage device can be registered. The transport device is set up to be activated in dependence on an output signal from the sensor device upon registering a predetermined operating condition of the cryogenic storage device, so that the sample carrying device is moved from the cryogenic container to the intermediate storage container. Additionally or alternatively, an intermediate storage cooling device that is set up for cooling the intermediate storage container can be activated in dependence on an output signal of the sensor device.
摘要翻译：本发明涉及一种低温存储装置和一种用于运行低温存储装置，特别是用于低温存储生物样本的方法，该装置包括设置成容纳样本的样本承载装置，设置成容纳样本携带装置，能够冷却低温容器的容器冷却装置，设置用于中间存储样本携带装置的中间存储容器，用于使样本携带装置能够在低温容器以及中间存储容器和传感器装置，通过该传感器装置可以注册低温存储装置的至少一个操作参数。在登记低温储存装置的预定操作条件时，根据来自传感器装置的输出信号设置传送装置以使得样品传送装置从低温容器移动到中间储存容器。附加地或替代地，可以根据传感器装置的输出信号来激活用于冷却中间存储容器的中间存储冷却装置。

82. 发明授权

EP1467620B1 KRYOSPEICHEREINRICHTUNG MIT TRANSPONDER 有权
标题翻译： Cryostorage应答器
公开(公告)号：EP1467620B1
公开(公告)日：2010-05-26
申请号：EP03702498.1
申请日：2003-01-22
申请人： Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
发明人： ZIMMERMANN, Heiko , FUHR, Günter , HAGEDORN, Rolf
IPC分类号： A01N1/02 , G01N1/42
CPC分类号： G01N1/42 , A01N1/02 , A01N1/0263 , B01L3/545 , B01L2300/022 , F25D29/001 , F25D2700/08 , G01N35/00732 , G01N35/00871 , G01N2035/00782 , G06K7/0008 , G06K19/0723 , G06K19/07758
摘要： The invention relates to a method for operating a cryogenic storage device (100), in particular for biological samples. Said device comprises a sample carrier (10) for receiving at least one sample (11) and a data memory (20). The device is characterised in that data is transmitted inductively by the data memory (20) to a wireless transmission channel (40) and/or vice versa, by means of a resonant circuit (30) that is connected to the data memory (20).

83. 发明公开

EP2134831A2 VORRICHTUNG UND VERFAHREN ZUR DEPOSITION VON BIOLOGISCHEM MATERIAL IN EINEM ZIELSUBSTRAT 有权
标题翻译：设备和方法的生物材料在目标基板沉积
公开(公告)号：EP2134831A2
公开(公告)日：2009-12-23
申请号：EP08714237.8
申请日：2008-01-28
申请人： Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
发明人： ZIMMERMANN, Heiko , FUHR, Günter, R.
IPC分类号： C12M3/00 , A61M5/00
CPC分类号： C12M35/08 , C12M35/00 , C12M41/12
摘要： Disclosed is a deposition apparatus (100) which is designed to deposit frozen biological material (1) in a target substrate (2) and comprises a charging device (10) and a driving device (20). The charging device (10) is designed to supply the biological material (1) to the driving device (20) while the driving device (20) is designed to apply a driving force to the biological material (1). In order to apply the driving force, the driving device (20) is formed such that the biological material (1) can penetrate into the target substrate (2) under the effect of the driving force. Also disclosed are an injector cartridge which is designed to provide frozen biological material in a deposition apparatus as well as a method for depositing biological material (1) in a target substrate (2).

84. 发明授权

EP2057330B1 TIEFSEEAQUARIUM UND ZUGEHÖRIGES BETRIEBSVERFAHREN 有权
标题翻译：德克萨斯州立大学的德克萨斯州立大学
公开(公告)号：EP2057330B1
公开(公告)日：2009-12-09
申请号：EP07801972.6
申请日：2007-08-29
申请人： Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V.
发明人： FUHR, Günter , ZIMMERMANN, Heiko
IPC分类号： E21D7/00 , A01K63/00
CPC分类号： A01K63/003 , A01K61/10 , A01K61/20 , A01K61/30 , A01K61/50 , A01K61/54 , A01K63/00 , B63C11/06 , B63C11/36 , B66B9/00 , B66B9/10 , E21D7/00

85. 发明授权

EP1558390B1 VERFAHREN ZUR BESCHICKUNG VON PROBENKAMMERN MIT SUSPENSIONSPROBEN 有权
标题翻译：方法悬架的饲料样品的样品室的
公开(公告)号：EP1558390B1
公开(公告)日：2007-05-30
申请号：EP03775301.9
申请日：2003-11-05
申请人： Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
发明人： FUHR, Günter , ZIMMERMANN, Heiko , HAGEDORN, Rolf
IPC分类号： B01L3/00 , A01N1/02 , G01N1/42
CPC分类号： B01L3/5085 , A01N1/02 , A01N1/0268 , B01L2200/0673 , B01L2300/0832 , B01L2300/087 , B01L2300/123 , B01L2300/1894 , G01N1/42
摘要： The invention relates to a cryopreservation device and to a method for supplying a sample chamber (10) with a suspension sample (20), especially for the cryopreservation of biological samples. According to the invention, partial samples (21, 22, 23, ) are positioned in the sample chamber (10) in such a way that they are separated by gas-filled free spaces (30).

86. 发明公开

EP1673609A2 VORRICHTUNG UND VERFAHREN ZUR HANDHABUNG EINER KRYOPROBE 有权
标题翻译：装置和方法用于处理cryosample
公开(公告)号：EP1673609A2
公开(公告)日：2006-06-28
申请号：EP04741139.2
申请日：2004-07-19
申请人： Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
发明人： FUHR, Günter, R. , SCHÖN, Uwe , ZIMMERMANN, Heiko , OH, Young-Joo, IBMT Fraunhofer Institut
IPC分类号： G01N1/42
CPC分类号： G01N1/42 , A01N1/0252 , B25J21/02
摘要： The invention relates to a device and method for handling a probe, in particular, for treating, examining, inserting or extracting a cryoprobe. According to the invention, said probe is surrounded by an ambient gas, during handling, and an air-conditioning device (33) cools, dries and/or at least partially replaces the ambient gas by a protective gas, in order to prevent deterioration of the probe by the ambient gas during handling.

87. 发明公开

EP1671100A1 KÜHLEINRICHTUNG ZUR KRYOKONSERVIERUNG UND ENTSPRECHENDES BET RIEBSVERFAHREN 有权转让
标题翻译：冷却装置冷冻保存及相应BET GROUND程序
公开(公告)号：EP1671100A1
公开(公告)日：2006-06-21
申请号：EP04790154.1
申请日：2004-10-06
申请人： Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
发明人： SCHÖN, Uwe , ZIMMERMANN, Heiko , FUHR, Günter
IPC分类号： G01N1/42 , B01L7/00 , G05D23/20
CPC分类号： F25D3/10 , A01N1/02 , A01N1/0257 , B01L7/00 , F25D29/001 , F25D2700/12 , G01N1/42
摘要： The invention relates to a cooling apparatus, especially for cryogenically preserving biological samples, comprising a duct (5) for delivering a coolant (3) to a cooling chamber (1), a heater (6) that has an adjustable first heating performance (P2) for heating the coolant (3) delivered to the cooling chamber (1), a first temperature sensor (8-10) for measuring the temperature (T2-T4) in the cooling chamber (1), a second temperature sensor (7) for measuring the temperature (T1) of the coolant (3) delivered to the cooling chamber (1), and a regulator (11) for regulating the temperature. Said regulator (11) is embodied as a multiple regulator which detects several temperatures (T1-T4) as control variables and/or adjusts several heating performances (P1, P2) as manipulated variables. The invention further relates to a corresponding operating method.

88. 发明公开

EP1636566A1 PROBENAUFNAHMEENIRICHTUNG UND VERFAHREN ZU DEREN HERSTELLUNG 有权
标题翻译： PROBENAUFNAHMEENIRICHTUNG和方法及其
公开(公告)号：EP1636566A1
公开(公告)日：2006-03-22
申请号：EP04740219.3
申请日：2004-06-23
申请人： Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
发明人： FUHR, Günter , ZIMMERMANN, Heiko , FIXEMER, Thomas
IPC分类号： G01N1/42 , B01L3/00
CPC分类号： B01L3/505 , B01L3/545 , B01L9/06 , B01L9/065 , B01L2300/024 , B01L2300/0832 , B01L2300/0838 , G01N1/42
摘要： The invention relates to a sample holding device (100), particularly for cryopreserving at least one sample, which has a bundle (10) consisting of a multitude of tubular flexible sample compartments (11, 12, ) and a retaining device (20), to which the bundle (10) of sample compartments is connected. The retaining device (20) has a multitude of retaining frames (21, 22, ) that are arranged in a longitudinal direction of the bundle (10).

89. 发明公开

EP1594949A2 VERFAHREN UND VORRICHTUNG ZUR BILDUNG VON BIOLOGISCHEM ZELLMATERIAL 有权
标题翻译：方法和装置的形成生物细胞材料
公开(公告)号：EP1594949A2
公开(公告)日：2005-11-16
申请号：EP03785710.9
申请日：2003-12-02
申请人： Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
发明人： FUHR, Günter, R. , ZIMMERMANN, Heiko
IPC分类号： C12M3/00 , C12M1/26
CPC分类号： B01L3/021 , A61B10/0233 , A61B10/0283 , A61B2010/0208 , B01L2200/0647 , B01L2300/0838 , B01L2400/0415 , B01L2400/043 , B01L2400/0487 , C12M33/02 , C12M35/00 , G01N1/286 , G01N15/12 , G01N15/14 , G01N2015/1486 , G01N2015/1493
摘要： The invention relates to a method for the formation of cell material (20) comprising a plurality of biological cells (21) which have a predetermined geometric arrangement. Said method comprises the following steps; a manipulation tool (10) is provided with a tool body (11) whose surface (12, 14) at least partially rests on the cell material (20); the manipulation tool (10) is displaced by altering geometrical properties of the surface (12, 14) in such a manner that the geometrical arrangement of the cells (21) is altered. The invention also relates to a manipulation tool for carrying out said method.

90. 发明公开

EP4343634A1 VORRICHTUNG, ANORDNUNG UND SYSTEM ZUM BETREIBEN EINES HARDWARE-BASIERTEN KÜNSTLICHEN NEURONALEN NETZWERKS SOWIE VERFAHREN ZUM TRAINIEREN DERSELBEN 审中-公开
公开(公告)号：EP4343634A1
公开(公告)日：2024-03-27
申请号：EP22197087.4
申请日：2022-09-22
申请人： Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
发明人： ZIMMERMANN, Heiko , FUHR, Günter
IPC分类号： G06N3/063 , G06N3/082 , G06N3/084 , G06N3/09 , G06N3/067
摘要： Die Erfindung betrifft eine Vorrichtung zum Betreiben eines hardware-basierten künstlichen neuronalen Netzwerks, umfassend mindestens ein hardware-basiertes künstliches neuronales Netzwerk (11, 24, 32, 41, 51, 71, 81, 101, 111, 121, 131, 171) dadurch gekennzeichnet, dass die Vorrichtung mindestens eine Störeinrichtung (12, 22, 35, 42, 52a, 52b, 72, 82, 102, 112, 122, 132, 172) zum Einkoppeln mindestens eines Störsignals in mindestens einem Bereich des hardware-basierten künstlichen neuronalen Netzwerks und mindestens eine Koppeleinrichtung (15, 23, 34, 43, 53a, 53b, 73, 83, 103, 113, 123, 133, 173) aufweist, wobei die Koppeleinrichtung zwischen der Störeinrichtung und dem hardware-basierten künstlichen neuronalen Netzwerk angeordnet ist und zum Übertragen des mindestens einen Störsignals von der Störeinrichtung zu dem mindestens einen Bereich ausgebildet ist. Weiter betrifft die Erfindung ein Verfahren zum Trainieren der Vorrichtung. Mit der Erfindung wird ein verbessertes hardware-basiertes künstliches neuronales Netzwerk bereitgestellt, das eine verbesserte Leistungsfähigkeit aufweist.

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