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81. 发明申请

WO2008079395A1 CROSSLINKABLE VINYL FLUORIDE COPOLYMER COATED FILM AND PROCESS FOR MAKING SAME 审中-公开
标题翻译：可交联的氟乙烯共聚物涂膜及其制备方法
公开(公告)号：WO2008079395A1
公开(公告)日：2008-07-03
申请号：PCT/US2007/026287
申请日：2007-12-21
申请人： E. I. DU PONT DE NEMOURS AND COMPANY , DUPONT-MITSUI FLUOROCHEMICALS COMPANY, LTD. , USCHOLD, Ronald, Earl , WANG, Jian , YAMAMOTO, Masahiro
发明人： USCHOLD, Ronald, Earl , WANG, Jian , YAMAMOTO, Masahiro
IPC分类号： C08F214/20 , C08F214/18
CPC分类号： C08F214/20 , C08F214/18 , C08F214/202 , Y10T428/2495 , Y10T428/24967 , Y10T428/26 , Y10T428/263 , Y10T428/264 , Y10T428/265 , Y10T428/266 , Y10T428/269 , Y10T428/3154 , Y10T428/31544 , Y10T428/31721 , Y10T428/31725 , Y10T428/3175 , Y10T428/31794 , Y10T428/31797 , Y10T428/31935
摘要： The invention provides a fluoropolymer coated film comprising: a polymeric substrate film; and a fluoropolymer coating on thepolymeric substrate film, the fluoropolymer coating comprising a vinyl fluoride copolymer comprised of about 40 to about 90 mole % of repeat units derived from vinyl fluoride and about 10 to about 60 mole % of repeat units derived from monomer selected from the group consisting of (a) and (b) below and mixtures thereof, with the proviso that about 0.1 mole % to 50 mole % of repeat units in the copolymer are derived from monomer selected from (b): (a) monomer selected from the group consisting of, tetrafluoroethylene, trifluoroethylene, chlorotrifluoroethylene and mixtures thereof; and (b) vinyl monomer containing at least one functional group selected from the group consisting of hydroxyls, thiols, carbonyls, carboxylic acids, carboxylic esters, acid anhydrides, sulfonyls, sulfonic acids, sulfonic esters, phosphoric acids, phosphoric esters, boric acids, boric esters, epoxies, isocyanates, thiocyanates, amines, amides, nitriles and halogen selected from bromide and iodide, wherein the polymeric substrate film comprises functional groups that interact with the functional groups of the vinyl fluoride copolymer to promote bonding of the fluoropolymer coating to the polymeric substrate film.
摘要翻译：本发明提供一种含氟聚合物涂覆膜，包括：聚合物基底膜; 和含氟聚合物涂层，所述含氟聚合物涂层包含由约40至约90摩尔％的衍生自氟乙烯的重复单元的乙烯基氟共聚物和约10至约60摩尔％的源自选自以下的单体的重复单元：由（a）和（b）组成的组和其混合物，共聚物中约0.1摩尔％至50摩尔％的重复单元衍生自选自（b）的单体：（a）选自由四氟乙烯，三氟乙烯，三氟氯乙烯及其混合物组成的组; 和（b）含有至少一种选自羟基，硫醇，羰基，羧酸，羧酸酯，酸酐，磺酰基，磺酸，磺酸酯，磷酸，磷酸酯，硼酸等的官能团的乙烯基单体，硼酸酯，环氧化物，异氰酸酯，硫氰酸酯，胺，酰胺，腈和选自溴化物和碘化物的卤素，其中聚合物基底膜包含与氟乙烯共聚物的官能团相互作用以促进含氟聚合物涂层与聚合物基底膜。

82. 发明申请

WO2008064152A2 METHOD FOR PRODUCING HETEROGENEOUS CATALYSTS CONTAINING METAL NANOPARTICLES 审中-公开
标题翻译：生产含有金属纳米颗粒的异构催化剂的方法
公开(公告)号：WO2008064152A2
公开(公告)日：2008-05-29
申请号：PCT/US2007/085091
申请日：2007-11-19
申请人： NANOSTELLAR, INC. , JIA, Jifei , WANG, Jian , FUJDALA, Kyle L.
发明人： JIA, Jifei , WANG, Jian , FUJDALA, Kyle L.
IPC分类号： B01J37/02
CPC分类号： B01J37/0018 , B01D53/945 , B01D2255/1021 , B01D2255/1023 , B01D2255/206 , B01D2255/2092 , B01D2255/40 , B01D2255/9207 , B01D2257/404 , B01D2257/406 , B01D2257/502 , B01D2257/702 , B01D2258/012 , B01J23/40 , B01J23/42 , B01J23/44 , B01J23/63 , B01J35/023 , B01J37/0036 , B01J37/0203 , B01J37/0215 , B01J37/0248 , B01J37/16 , Y02T10/22
摘要： A monomer is added to a solvent containing metal salt and porous support materials and the solvent is stirred for a period of time to distribute and fix the metal in the pores of the support materials. The solids that are dispersed in the solvent are then separated from the liquid, dried and calcined to form heterogeneous catalysts. The monomer that is added is of a type that can be polymerized in the solvent to form oligomers or polymers, or both. When forming heterogeneous catalysts containing platinum, acrylic acid is selected as the preferred monomer.
摘要翻译：将单体加入到含有溶剂的金属盐和多孔载体材料中，并将溶剂搅拌一段时间以将金属分散并固定在载体材料的孔中。然后将分散在溶剂中的固体与液体分离，干燥并煅烧以形成非均相催化剂。所添加的单体是可以在溶剂中聚合以形成低聚物或聚合物或两者的类型。当形成含有铂的非均相催化剂时，选择丙烯酸作为优选的单体。

83. 发明申请

WO2007120647A3 COMPOSITIONS USEFUL AS INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS 审中-公开
公开(公告)号：WO2007120647A3
公开(公告)日：2007-10-25
申请号：PCT/US2007/008818
申请日：2007-04-11
申请人： VERTEX PHARMACEUTICALS INCORPORATED , JOSHI, Pramod , KRENITSKY, Paul , GONZALEZ, Jesus , WANG, Jian , WILSON, Dean , TERMIN, Andreas
发明人： JOSHI, Pramod , KRENITSKY, Paul , GONZALEZ, Jesus , WANG, Jian , WILSON, Dean , TERMIN, Andreas
IPC分类号： C07C311/46 , C07D207/32 , C07D213/74 , C07D233/54 , C07D295/20 , C07D317/60 , C07C323/62 , C07D213/65 , C07D239/34 , A61K31/18 , A61P29/00
摘要： The present invention relates to compounds, particularly those of formula (I'), where R, R 1 , R 2 , R 3 , R 4 , x and z are as defined in the claims, useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

84. 发明申请

WO2007033130A1 VINYL FLUORIDE-BASED COPOLYMER BINDER FOR BATTERY ELECTRODES 审中-公开
标题翻译：用于电池电极的基于氟的氟化物共聚物粘合剂
公开(公告)号：WO2007033130A1
公开(公告)日：2007-03-22
申请号：PCT/US2006/035411
申请日：2006-09-12
申请人： E. I. DU PONT DE NEMOURS AND COMPANY , DUPONT-MITSUI FLUOROCHEMICALS COMPANY, LTD. , WANG, Jian , MOCHIZUKI, Shunsuke , USCHOLD, Ronald, Earl
发明人： WANG, Jian , MOCHIZUKI, Shunsuke , USCHOLD, Ronald, Earl
IPC分类号： C08F214/20 , C08L27/14 , H01M4/62
CPC分类号： C08F214/20 , C08L27/14 , C08L27/16 , C08L2205/02 , C09D127/16 , H01M4/621 , H01M4/622 , H01M4/623 , C08L2666/04
摘要： A binder for a battery electrode comprising a vinyl fluoride-based copolymer. The vinyl fluoride-based copolymer preferably comprises about 25 to about 85 mol% vinyl fluoride and about 75 to about 15 mol% of at least one other fluorine-containing monomer. In a preferred embodiment, the binder comprises a mixture of at least two types of vinyl fluoride-based copolymers. In another embodiment the binder comprises a vinyl fluoride-based copolymer and at least one other fluorine-based polymer. The binder can be dispersed in water or organic solvent to form a paste for binding electrode materials to current collectors for battery electrode fabrication. Battery electrodes with improved adhesion strength and electrochemical stability result.
摘要翻译：一种用于包含氟乙烯基共聚物的电池电极的粘合剂。氟乙烯基共聚物优选包含约25至约85mol％的氟化乙烯和约75至约15mol％的至少一种其它含氟单体。在优选的实施方案中，粘合剂包含至少两种类型的基于氟乙烯的共聚物的混合物。在另一个实施方案中，粘合剂包括基于氟乙烯的共聚物和至少一种其它氟基聚合物。粘合剂可以分散在水或有机溶剂中以形成用于将电极材料粘合到用于电池电极制造的集电器的糊料。具有改善粘合强度和电化学稳定性的电池电极。

85. 发明申请

WO2005082057A2 CONTROLLING REMOVAL RATE UNIFORMITY OF AN ELECTROPOLISHING PROCESS IN INTEGRATED CIRCUIT FABRICATION 审中-公开
标题翻译：一体化电路制造中电解过程的去除速率均匀性的控制
公开(公告)号：WO2005082057A2
公开(公告)日：2005-09-09
申请号：PCT/US2005/006142
申请日：2005-02-23
申请人： ACM RESEARCH, INC. , WANG, Hui , AFNAN, Muhammed , WANG, Jian , GUTMAN, Felix , HO, Frederick , CHOKSHI, Himanshu, J.
发明人： WANG, Hui , AFNAN, Muhammed , WANG, Jian , GUTMAN, Felix , HO, Frederick , CHOKSHI, Himanshu, J.
CPC分类号： B23H5/08 , B24B37/04 , C25F3/02 , C25F5/00 , C25F7/00 , H01L21/32115
摘要： A metal layer formed on a wafer, the wafer having a center portion and an edge portion, is electropolished by aligning a nozzle and the wafer to position the nozzle adjacent to the center portion of the wafer. The wafer is rotated. As the wafer is rotated, a stream of electrolyte is applied from the nozzle onto a portion of the metal layer adjacent to the center portion of the wafer to begin to electropolish the portion of the metal layer with a triangular polishing profile to initially expose an underlying layer underneath the metal layer at a point.
摘要翻译：在晶片上形成的金属层（具有中心部分和边缘部分的晶片）通过对准喷嘴和晶片以将喷嘴定位成与晶片的中心部分相邻来进行电抛光。晶圆旋转。当晶片旋转时，电解质流从喷嘴施加到与晶片的中心部分相邻的金属层的一部分上，以开始以三角抛光轮廓对金属层的部分进行电解抛光，以最初暴露下面的在一点上金属层下方的层。

86. 发明申请

WO2005055283A2 MONITORING AN ELECTROPOLISHING PROCESS IN INTEGRATED CIRCUIT FABRICATION 审中-公开
标题翻译：监控整合电路制造中的电镀工艺
公开(公告)号：WO2005055283A2
公开(公告)日：2005-06-16
申请号：PCT/US2004/039748
申请日：2004-11-26
申请人： ACM RESEARCH, INC. , WANG, Hui , YIP, Henry , WANG, Jian , YU, Chaw-Chi
发明人： WANG, Hui , YIP, Henry , WANG, Jian , YU, Chaw-Chi
IPC分类号： H01L
CPC分类号： C25F3/16 , H01L22/14 , H01L22/26
摘要： An electropolishing process of a metal layer formed on a wafer used in integrated circuit fabrication includes rotating the wafer. As the wafer is rotated, a stream of electrolyte is applied through a nozzle to the metal layer at a first radial location on the wafer. The electropolishing process is monitored by measuring electrical resistance at the first radial location. The electrical resistance measured at the first radial location is compared to a first preset electrical resistance associated with the first radial location. An electropolishing charge applied at the first radial location is controlled based on the comparison of the electrical resistance measured at the first radial location to the first preset electrical resistance associated with the first radial location. After applying the stream of electrolyte at the first radial location, the stream of electrolyte is applied at a second radial location. Electrical resistance at the second radial location is measured. The electrical resistance measured at the second radial location is compared to a second preset electrical resistance, which is different than the first preset electrical resistance, associated with the second radial location. The electropolishing charge applied at the second radial location is controlled based on the comparison of the electrical resistance measured at the second radial location to the second preset electrical resistance associated with the second radial location.
摘要翻译：在用于集成电路制造的晶片上形成的金属层的电抛光工艺包括旋转晶片。当晶片旋转时，电晶体流通过喷嘴在晶片上的第一径向位置处施加到金属层。通过测量第一径向位置处的电阻来监测电抛光过程。将在第一径向位置处测量的电阻与与第一径向位置相关联的第一预设电阻进行比较。基于在第一径向位置处测量的电阻与与第一径向位置相关联的第一预设电阻的比较来控制施加在第一径向位置处的电抛光电荷。在第一径向位置施加电解质流之后，在第二径向位置施加电解质流。测量第二径向位置处的电阻。将在第二径向位置处测量的电阻与与第二径向位置相关联的第一预设电阻不同的第二预设电阻进行比较。基于在第二径向位置处测量的电阻与与第二径向位置相关联的第二预设电阻的比较来控制施加在第二径向位置处的电抛光电荷。

87. 发明申请

WO2005024009A1 MODULATION OF HAIR GROWTH VIA SGK3 审中-公开
标题翻译：通过SGK3调制头发生长
公开(公告)号：WO2005024009A1
公开(公告)日：2005-03-17
申请号：PCT/EP2004/009907
申请日：2004-09-06
申请人： EBERHARD-KARLS-UNIVERSITÄT TÜBINGEN UNIVERSITÄTSKLINIKUM , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , LANG, Florian , PEARCE, David , WANG, Jian , McCORMICK, James
发明人： LANG, Florian , PEARCE, David , WANG, Jian , McCORMICK, James
IPC分类号： C12N9/12
CPC分类号： C12N9/1205 , C12Y207/01037
摘要： The present invention relates to methods for identifying a hair growth modulating substance, to methods for preparing a pharmaceutical/cosmetic composition for treatment of hair growth disorders, to methods for treating a human being affected by a hair growth disorder, to hair growth modulating substances, to compositions comprising a substance which modulates the activity of SGK3 or causes a modulation of the activity of a SGK3-derived peptide in the above-mentioned "identifying"-methods, and to a transgenic non-human sgk3-1- animal for investigating hair growth disorders.
摘要翻译：本发明涉及用于鉴定毛发生长调节物质的方法，制备用于治疗毛发生长障碍的药物/化妆品组合物的方法，治疗受毛发生长障碍的人的治疗方法，毛发生长调节物质，涉及包含调节SGK3活性或在上述“鉴定”方法中调节SGK3衍生肽的活性的物质的组合物和用于调查头发的转基因非人sgk3-1-动物生长障碍。

88. 发明申请

WO2004035068A1 USE OF ENTERIC GLIA TO PROMOTE FUNCTIONAL NERVE CONNECTIONS 审中-公开
标题翻译：使用Enteric GLIA促进功能性神经连接
公开(公告)号：WO2004035068A1
公开(公告)日：2004-04-29
申请号：PCT/CA2003/001549
申请日：2003-10-15
申请人： NEUROLOGICAL TECHNOLOGIES INC. , RATHBONE, Michel, P. , JIANG, Shucui , WANG, Jian , MIDDLEMISS, Pamela , KHAN, Mohammad, Imtiaz
发明人： RATHBONE, Michel, P. , JIANG, Shucui , WANG, Jian , MIDDLEMISS, Pamela , KHAN, Mohammad, Imtiaz
IPC分类号： A61K35/30
CPC分类号： A61K35/30
摘要： Methods of promoting functional regeneration of injured nerve fibres are described. The methods involve administering enteric glial cells to an animal with a nerve injury or neurdegenerative disease. The method is also useful in inducing formation of a blood-brain barrier in the nervous system.
摘要翻译：描述了促进受损神经纤维功能再生的方法。所述方法涉及将神经胶质细胞给予具有神经损伤或神经变性疾病的动物。该方法也可用于诱导神经系统中血脑屏障的形成。

89. 发明申请

WO2003044164A3 CELL SUBSTRATES AND METHODS OF USE THEREOF 审中-公开
公开(公告)号：WO2003044164A3
公开(公告)日：2003-05-30
申请号：PCT/US2002/036546
申请日：2002-11-13
申请人： UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL , GERBER, David, A. , WANG, Jian
发明人： GERBER, David, A. , WANG, Jian
IPC分类号： C12M3/00 , C12N11/04 , C12N5/00
摘要： A cell support system useful for the implantation of living cells in a subject comprises a solid substrate, typically formed from a biologically inert material. The substrate has a textured surface portion, with the textured surface portion defining a plurality of recessed cavities therein. A plurality of live cells to be implanted are deposited on the textured surface portion so that the cells (or progeny thereof) are protected from mechanical dislodgment.

90. 发明申请

WO2002096905A1 THIAZOLE COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN KINASES 审中-公开
标题翻译：噻唑化合物作为蛋白激酶的抑制剂有用
公开(公告)号：WO2002096905A1
公开(公告)日：2002-12-05
申请号：PCT/US2002/016352
申请日：2002-05-23
申请人： VERTEX PHARMACEUTICALS INCORPORATED , COCHRAN, John , NANTHAKUMAR, Suganthini , HARRINGTON, Edmund , WANG, Jian
发明人： COCHRAN, John , NANTHAKUMAR, Suganthini , HARRINGTON, Edmund , WANG, Jian
IPC分类号： C07D417/04
CPC分类号： C07D405/06 , C07D231/12 , C07D233/56 , C07D249/08 , C07D405/14 , C07D417/04 , C07D417/14 , C07D487/10 , C07F7/1856 , C07F9/6561
摘要： The present invention provides a compound of formula I: or a pharmaceutically acceptable derivative thereof. These compounds are inhibitors of protein kinases, particularly inhibitors of GSK3, Aurora2, and Syk mammalian protein kinases. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of utilizing those compounds and compositions in the treatement of various protein kinase mediated disorders.
摘要翻译：本发明提供式I化合物或其药学上可接受的衍生物。这些化合物是蛋白激酶的抑制剂，特别是GSK3，Aurora2和Syk哺乳动物蛋白激酶的抑制剂。本发明还提供包含本发明化合物的药学上可接受的组合物以及利用这些化合物和组合物来治疗各种蛋白激酶介导的病症的方法。

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