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81. 外观设计

USD319796S Air sampling gun for collection of vapors 失效
公开(公告)号：USD319796S
公开(公告)日：1991-09-10
申请号：US293142
申请日：1989-01-03
申请人： James B. McGown , Edward E. A. Bromberg , David H. Fine , A. Lindsay Carroll, Jr. , Michel D. Arney , Lynn Noble
设计人： James B. McGown , Edward E. A. Bromberg , David H. Fine , A. Lindsay Carroll, Jr. , Michel D. Arney , Lynn Noble

82. 发明授权

US4843016A Detection system and method 失效
标题翻译：检测系统及方法
公开(公告)号：US4843016A
公开(公告)日：1989-06-27
申请号：US19029
申请日：1987-02-26
申请人： David H. Fine
发明人： David H. Fine
IPC分类号： G01N30/02 , G01N30/84 , G01N31/12
CPC分类号： G01N31/12 , G01N30/84 , G01N2030/025 , G01N2030/8405 , Y10T436/17 , Y10T436/177692
摘要： A detection system for detecting the presence of predetermined compounds in a sample. The system comprises a sample injection means, a chromatographic column, a conversion means and one or more specific gas detectors. The conversion means transforms the column effluent to combustion products in the gas phase, after which those combustion products are transferred to the specific gas detectors. In one embodiment for detecting nitrogen compounds, the conversion means includes an oxygen-rich flame, a means to control the flame to have a temperature in the range 600.degree.-1700.degree. C., means to inject the column effluent into the flame, and an input port for transferring the flame effluent to a specific nitrogen detector.
摘要翻译：用于检测样品中预定化合物的存在的检测系统。该系统包括样品注入装置，色谱柱，转化装置和一种或多种特定气体检测器。转化装置将柱流出物转化为气相中的燃烧产物，之后将这些燃烧产物转移到特定的气体检测器。在用于检测氮化合物的一个实施方案中，转化装置包括富氧火焰，控制火焰温度在600°-1700℃范围内的手段，意味着将柱流出物注入到火焰中，以及用于将火焰流出物转移到特定氮气检测器的输入端口。

83. 发明授权

US4778764A Detection system and method 失效
标题翻译：检测系统及方法
公开(公告)号：US4778764A
公开(公告)日：1988-10-18
申请号：US512374
申请日：1974-10-07
申请人： David H. Fine
发明人： David H. Fine
IPC分类号： G01N21/76 , G01N30/02 , G01N30/74 , G01N30/84 , G01N30/88 , G01N31/00 , G01N31/12
CPC分类号： G01N31/12 , G01N30/84 , G01N2030/025 , G01N2030/8405 , Y10T436/176152 , Y10T436/177692 , Y10T436/186 , Y10T436/19
摘要： A detection system for detecting the presence of predetermined compounds in a sample. The system comprises a sample injection means, a chromatographic column, a conversion means and one or more specific gas detectors. The conversion means transforms the column effluent to combustion products in the gas phase, after which those combustion products are transferred to the specific gas detectors. In one embodiment for detecting nitrogen compounds, the conversion means includes an oxygen-rich flame, a means to control the flame to have a temperature in the range 600.degree.-1700.degree. C., means to inject the column effluent into the flame, and an output port for transferring the flame effluent to a specific nitrogen detector.
摘要翻译：用于检测样品中预定化合物的存在的检测系统。该系统包括样品注入装置，色谱柱，转化装置和一种或多种特定气体检测器。转化装置将柱流出物转化为气相中的燃烧产物，之后将这些燃烧产物转移到特定的气体检测器。在用于检测氮化合物的一个实施方案中，转化装置包括富氧火焰，控制火焰温度在600°-1700℃范围内的手段，意味着将柱流出物注入到火焰中，以及用于将火焰流出物转移到特定氮气检测器的输出端口。

84. 发明授权

US4194884A Method and apparatus for air sampling and filtration 失效
标题翻译：空气取样和过滤的方法和装置
公开(公告)号：US4194884A
公开(公告)日：1980-03-25
申请号：US963626
申请日：1978-11-24
申请人： David P. Rounbehler , David H. Fine
发明人： David P. Rounbehler , David H. Fine
IPC分类号： G01N1/22 , G01N33/00 , G01N31/06 , G01N31/08 , G01N31/12
CPC分类号： G01N33/0011 , Y10T436/170769 , Y10T436/173845
摘要： Methods and apparatus for removing compounds from air to clean the air and for providing quantitative analysis of the content of particular organic compounds in the air. Apparatus is described having a separation zone packed with a magnesium silicate or calcium silicate material in the form of finely divided particles which are effective in trapping and holding substantially all of certain predetermined compounds present in air passed through the material. The silicate-packed separation zone may be employed as a highly efficient filter to purify air containing pollutants or contaminants. Also described are a method and apparatus for accurately determining the content of predetermined organic compounds in a sample of air using a collection tube containing a sorbent material such as dry, finely divided activated magnesium trisilicate. The method involves passing air through the sorbent material for a specified interval of time to trap the predetermined compounds, applying a solvent in the opposite direction to the flow of air to transfer all of selected compounds to a small quantity of solvent to form a solution, collecting the solution as it emerges from the material, and then analyzing the collected solution without concentrating it. One set of compounds of interest are highly carcinogenic N-nitroso compounds which may be present in air in minute quantities.
摘要翻译：从空气中除去化合物以清洁空气并提供空气中特定有机化合物的含量的定量分析的方法和装置。描述了装置，其具有填充有细碎颗粒形式的硅酸镁或硅酸钙材料的分离区，其有效捕获并保持通过材料的空气中存在的基本上所有的某些预定化合物。硅酸盐填充分离区可用作高效过滤器以净化含有污染物或污染物的空气。还描述了一种用于使用含有吸附剂材料（例如干燥，细碎的活化的三硅酸镁）的收集管来精确测定空气样品中预定有机化合物的含量的方法和装置。该方法包括使空气通过吸附剂材料达指定的时间间隔以捕获预定化合物，向与空气流相反的方向施加溶剂以将所有选定的化合物转移至少量溶剂以形成溶液，从材料中收集溶液，然后分析收集的溶液而不集中。一组感兴趣的化合物是高度致癌的N-亚硝基化合物，其可以以微量存在于空气中。

85. 发明授权

US4066409A Method and apparatus for chromatographically analyzing a liquid sample 失效
标题翻译：用于色谱分析液体样品的方法和装置
公开(公告)号：US4066409A
公开(公告)日：1978-01-03
申请号：US760604
申请日：1977-01-19
申请人： David H. Fine
发明人： David H. Fine
IPC分类号： G01N30/84 , G01N31/00 , G01N31/08
CPC分类号： G01N31/005 , Y10T436/176152 , Y10T436/188
摘要： A chromatographic system is provided for detecting in a liquid sample the presence of organic nitrogen containing compounds. A liquid chromatograph separates constituents of the liquid sample and discharges the separated constituents in a timewise distribution. Effluent from the chromatograph is atomized into a converter and there oxidized at a temperature approximately in the range 600.degree. to 800.degree. C for converting the nitrogen in the organic nitrogen containing compound to nitric oxide. Sufficient oxygen is supplied to the converter to fully oxidize the sample introduced therein. Effluent is transferred from the converter to a nitric oxide detector which measures the nitric oxide present in the converted sample and thereby provides a measurement of the organic nitrogen containing compound in the sample.In an alternate embodiment for use with sulphur containing organic compounds, the effluent from the chromatograph, when atomized into the converter and oxidized, may be transferred to a sulphur dioxide detector. The indication of sulphur dioxide present in the sulphur dioxide detector corresponds to the content of organic sulphur containing compounds in the sample.

86. 发明授权

US10113983B1 Explosives vapor detector 失效
公开(公告)号：US10113983B1
公开(公告)日：2018-10-30
申请号：US06732449
申请日：1985-05-09
申请人： David H. Fine , Freeman W. Fraim , James E. Buckley
发明人： David H. Fine , Freeman W. Fraim , James E. Buckley
IPC分类号： G01N1/02 , G01N24/08
摘要： Disclosed are a highly selective, highly sensitive method and apparatus for detecting vapors from explosives at low concentrations such as 1 part in 1014. Airborne explosives vapors are selectively adsorbed on a spiral-wound platinum or platinum-coated ribbon of a preconcentrator cartridge while trapping of nitrogen oxides is avoided. The vapors are released and partially decomposed to liberate nitric oxide gas by flash-heating of the ribbon, these products may then be pyrolyzed if necessary to complete the liberation of nitric oxide gas, and then the liberated nitric oxide gas is detected, as by chemiluminescent detection. Also described are various systems incorporating the explosives vapor detector such as a walk-through portal, a vehicle sniffer, and a system incorporated into the air-handling apparatus of a building. A walk-through explosives detection system is disclosed having a carousel containing an array of preconcentrator cartridges for rapid acquisition and analysis of explosives vapor samples, and which is capable of screening up to ten persons per minute for possession of explosives.

87. 发明授权

US08613958B2 Nitric oxide therapies 有权
公开(公告)号：US08613958B2
公开(公告)日：2013-12-24
申请号：US12819670
申请日：2010-06-21
申请人： David H. Fine
发明人： David H. Fine
IPC分类号： A61K33/00 , A61M15/00 , A62B7/10 , A61M16/10
CPC分类号： A61M16/12 , A61K9/0043 , A61K9/0073 , A61K9/7023 , A61K31/655 , A61K33/00 , A61K47/02 , A61M5/165 , A61M15/00 , A61M15/08 , A61M15/085 , A61M16/105 , A61M35/006 , A61M2005/006 , A61M2202/0275 , A61M2205/75
摘要： A method for delivering nitric oxide therapy to a subject can include administering a composition including a nitric-oxide releasing agent and silica to the subject and releasing a therapeutic amount of nitric oxide from the composition.

88. 发明授权

US08609028B2 Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) 有权
公开(公告)号：US08609028B2
公开(公告)日：2013-12-17
申请号：US13555567
申请日：2012-07-23
申请人： David R. Rounbehler , David H. Fine
发明人： David R. Rounbehler , David H. Fine
IPC分类号： A62B7/08
CPC分类号： A61M16/12 , A61D7/04 , A61M15/00 , A61M16/0057 , A61M16/10 , A61M16/104 , A61M2016/102 , A61M2202/0275 , C01B21/24
摘要： Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. A nitric oxide delivery system that converts nitrogen dioxide to nitric oxide employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid.

89. 发明申请

US20130037023A1 CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO) 有权
公开(公告)号：US20130037023A1
公开(公告)日：2013-02-14
申请号：US13587543
申请日：2012-08-16
申请人： David R. Rounbehler , David H. Fine
发明人： David R. Rounbehler , David H. Fine
IPC分类号： A61M16/12
CPC分类号： A61M16/122 , A61M15/00 , A61M16/10 , A61M2016/1025 , A61M2202/0275 , C01B21/24
摘要： A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.

90. 发明申请

US20120285449A1 PRESSURIZED VESSEL OF NITRIC OXIDE (NO) 审中-公开
标题翻译：氮氧化物加压容器（NO）
公开(公告)号：US20120285449A1
公开(公告)日：2012-11-15
申请号：US13492154
申请日：2012-06-08
申请人： David H. Fine , Bryan Johnson
发明人： David H. Fine , Bryan Johnson
IPC分类号： A61M16/12
CPC分类号： A61M16/12 , A61M16/10 , A61M16/122 , A61M2202/0275 , A61M2202/03 , C01B21/24
摘要： A pharmaceutical product can include a pressure vessel containing a pressurized gas including at least about 1% nitric oxide.
摘要翻译：药物产品可包括含有包含至少约1％一氧化氮的加压气体的压力容器。

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