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81. 发明授权

US06272377B1 Cardiac rhythm management system with arrhythmia prediction and prevention 有权
标题翻译：心律失常预防与心律失常管理系统
公开(公告)号：US06272377B1
公开(公告)日：2001-08-07
申请号：US09411345
申请日：1999-10-01
申请人： Robert J. Sweeney , Bruce H. KenKnight
发明人： Robert J. Sweeney , Bruce H. KenKnight
IPC分类号： A61B50468
CPC分类号： A61N1/3622 , G06F19/00 , G16H50/30
摘要： A cardiac rhythm management system predicts when an arrhythmia will occur and in one embodiment invokes a therapy to prevent or reduce the consequences of the arrhythmia. A cardiac arrhythmia trigger/marker is detected from a patient, and based on the trigger/marker, the system estimates a probability of a cardiac arrhythmia occurring during a predetermined future time interval. The system provides a list of triggers/markers, for which detection values are recurrently obtained at various predetermined time intervals. Based on detection values and conditional probabilities associated with the triggers/markers, a probability estimate of a future arrhythmia is computed. An arrhythmia prevention therapy is selected and activated based on the probability estimate of the future arrhythmia.
摘要翻译：心律管理系统预测何时发生心律失常，并且在一个实施例中调用治疗以预防或减少心律失常的后果。从患者检测到心律失常触发/标记，并且基于触发/标记，系统估计在预定的未来时间间隔期间发生心律失常的概率。该系统提供了一个触发/标记列表，为各种预定时间间隔循环获得检测值。基于与触发/标记相关联的检测值和条件概率，计算未来心律失常的概率估计。基于对未来心律失常的概率估计，选择并激活心律失常预防疗法。

82. 发明授权

US4721566A Tilting pan filters and cam therefor 失效
标题翻译：倾斜锅过滤器和凸轮
公开(公告)号：US4721566A
公开(公告)日：1988-01-26
申请号：US797967
申请日：1985-11-14
申请人： Donald L. Chamberlain , Robert J. Sweeney
发明人： Donald L. Chamberlain , Robert J. Sweeney
IPC分类号： B01D33/17 , B01D33/19 , B01D33/327 , B01D35/08
CPC分类号： B01D33/19
摘要： Tilting filter pans is disclosed having generally parallel leading and trailing sidewalls which are sloped at an angle to permit increased filtration rates for a predetermined filtering efficiency, and also to permit increased filtering efficiency where the feed rate is constant. The feed is a slurry from which the liquid is removed, and the filter cake being dumped by rotation of each filter pan at a predetermined point of movement of the filter pan along a cyclical path. Hold-down devices having a reduced volume are also used in combination with the improved pan design, so that an increased filtration rate is possible due to decrease in the required filter cake height. A cam arrangement is provided for turning the pans with minimum stress in a minimum length of pan travel, while avoiding collisions between adjacent pans and while permitting washing of each pan.
摘要翻译：公开了具有大致平行的前后侧壁的倾斜过滤盘，其倾斜一角度以允许提高过滤速率以达到预定的过滤效率，并且还允许提高进料速率恒定的过滤效率。进料是从其中除去液体的浆料，并且滤饼通过每个过滤盘的旋转沿着循环路径在过滤盘的预定运动点处倾倒。具有减小的体积的压紧装置也与改进的盘设计结合使用，使得由于所需滤饼高度的降低而可能提高过滤速率。提供一种凸轮装置，用于以最小长度的平移行程以最小应力转动平底锅，同时避免相邻平底锅之间的碰撞并且同时允许每个平底锅的洗涤。

83. 发明授权

US10027792B1 Systems and methods for notifying users of emergency impact zones 有权
公开(公告)号：US10027792B1
公开(公告)日：2018-07-17
申请号：US15620425
申请日：2017-06-12
申请人： Robert J. Sweeney
发明人： Robert J. Sweeney
IPC分类号： H04M11/04 , H04M1/725 , H04W4/02 , H04W4/22 , H04W4/90
摘要： An emergency notification (EN) computing device includes at least one processor and a memory in communication with the processor. The processor is programmed to receive, from a user device, an emergency report that identifies an emergency situation and is associated with a report location, receive user input defining an impact zone within a geographical region based on the report location and the emergency situation, collect location data from a plurality of mobile user devices associated with a plurality of bystanders, detect a first bystander located within the impact zone based on the location data, and automatically notify the first bystander of the emergency situation.

84. 发明授权

US09022930B2 Inter-relation between within-patient decompensation detection algorithm and between-patient stratifier to manage HF patients in a more efficient manner 有权
标题翻译：患者间代偿失调检测算法与病人间分层之间的相互关系以更有效的方式管理HF患者
公开(公告)号：US09022930B2
公开(公告)日：2015-05-05
申请号：US11616441
申请日：2006-12-27
申请人： Haresh G. Sachanandani , Krzysztof Z. Siejko , Jon Peterson , Shelley Cazares , Robert J. Sweeney , Kevin J. Stalsberg , Gerrard M. Carlson
发明人： Haresh G. Sachanandani , Krzysztof Z. Siejko , Jon Peterson , Shelley Cazares , Robert J. Sweeney , Kevin J. Stalsberg , Gerrard M. Carlson
IPC分类号： A61B5/00 , A61N1/372 , A61B5/0205 , A61N1/37 , G06F19/00
CPC分类号： A61N1/37282 , A61B5/0022 , A61B5/0205 , A61N1/3702 , G06F19/00 , G06F19/3418 , G16H40/63 , G16H50/20
摘要： This document discusses, among other things, systems and methods for using one or more inter-relations between within-patient detection methods and between-patient stratifier methods. A method comprises obtaining results of a first physiological assessment, wherein the first physiological assessment includes a between-patient assessment; and using the results to adjust one or more parameters of a second physiological assessment, wherein the second physiological assessment includes a within-patient assessment.
摘要翻译：本文件还讨论了在患者检测方法和患者间分层方法之间使用一个或多个相互关系的系统和方法。一种方法包括获得第一生理学评估的结果，其中所述第一生理学评估包括患者间评估; 以及使用所述结果来调整第二生理学评估的一个或多个参数，其中所述第二生理学评估包括患者内评估。

85. 发明授权

US08725250B2 Controlled titration of neurostimulation therapy 有权
标题翻译：神经刺激治疗的控制滴定
公开(公告)号：US08725250B2
公开(公告)日：2014-05-13
申请号：US13487877
申请日：2012-06-04
申请人： Marina V. Brockway , Imad Libbus , Krzysztof Z. Siejko , Robert J. Sweeney
发明人： Marina V. Brockway , Imad Libbus , Krzysztof Z. Siejko , Robert J. Sweeney
IPC分类号： A61N1/362
CPC分类号： A61N1/3727 , A61B5/02405 , A61B5/4035 , A61B5/4839 , A61N1/36114 , A61N1/36117 , A61N1/36139 , A61N1/362 , A61N1/37264
摘要： Described herein are methods and devices that utilize electrical neural stimulation to treat heart failure by modulating a patient's autonomic balance in a manner that inhibits sympathetic activity and/or augments parasympathetic activity. Because other therapies for treating heart failure may also affect a patient's autonomic balance, a device for delivering neural stimulation is configured to appropriately titrate such therapy in either an open-loop or closed-loop fashion.
摘要翻译：本文描述了利用电神经刺激来以抑制交感神经活动和/或增加副交感神经活动的方式调节患者的自主神经平衡来治疗心力衰竭的方法和装置。因为用于治疗心力衰竭的其它治疗也可能影响患者的自主平衡，用于递送神经刺激的装置被配置为以开环或闭环方式适当地滴定这种治疗。

86. 发明授权

US08649853B2 Cardiac function monitor using information indicative of lead motion 有权
标题翻译：心脏功能监测器使用指示引导运动的信息
公开(公告)号：US08649853B2
公开(公告)日：2014-02-11
申请号：US13168531
申请日：2011-06-24
申请人： Robert J. Sweeney , Allan C. Shuros , Krzysztof Z. Siejko , David C. Olson , Frank Ingle
发明人： Robert J. Sweeney , Allan C. Shuros , Krzysztof Z. Siejko , David C. Olson , Frank Ingle
IPC分类号： A61B5/04 , A61B17/04 , A61F2/00 , A61F13/00 , A61M1/10 , A61N1/00
CPC分类号： A61N1/36514 , A61B5/02133 , A61B5/026 , A61N1/08 , A61N1/36142 , A61N1/36578
摘要： Systems and methods to monitor cardiac function using information indicative of lead motion are described. In an example, a system including an implantable medical device can include a receiver circuit configured to be electrically coupled to conductor comprising a portion of an implantable lead and be configured to obtain information indicative of a movement of the implantable lead due at least in part to a motion of a heart. The system can include a sensing circuit configured to obtain information indicative of cardiac electrical activity. The system can include a processor circuit configured to construct a template representative of a contraction of the heart, where the template can be constructed using the information indicative of the movement of the implantable lead due at least in part to the motion of the heart during the contraction, and using the information indicative of the cardiac electrical activity sensed during the contraction.
摘要翻译：描述使用指示引导运动的信息来监测心脏功能的系统和方法。在一个示例中，包括可植入医疗装置的系统可以包括被配置为电耦合到导体的接收器电路，该导体包括可植入引线的一部分，并且被配置为获得指示可植入引线的移动的信息，一个心脏的动作。该系统可以包括被配置为获得指示心脏电活动的信息的感测电路。该系统可以包括配置成构造代表心脏收缩的模板的处理器电路，其中可以使用指示可植入导线的运动的信息构造模板，至少部分地由于心脏的运动并且使用指示在收缩期间感测到的心脏电活动的信息。

87. 发明授权

US08527047B2 Artificial conduction pathways in tachyarrhythmia 有权
标题翻译：快速性心律失常中的人造传导通路
公开(公告)号：US08527047B2
公开(公告)日：2013-09-03
申请号：US12751972
申请日：2010-03-31
申请人： Robert J. Sweeney
发明人： Robert J. Sweeney
IPC分类号： A61N1/365
CPC分类号： A61N1/3622
摘要： An implantable medical device can establish one or more artificial conduction pathways during tachyarrhythmia. Withdrawal of the artificial conduction pathway may help self-terminate the tachyarrhythmia, or may pre-condition the tachyarrhythmia to be more favorable for receiving an anti-tachyarrhythmia therapy, such as anti-tachyarrhythmia pacing, defibrillation shock therapy, or cardioversion. This can help provide enhanced anti-tachyarrhythmia therapy.
摘要翻译：可植入医疗装置可以在快速性心律失常期间建立一个或多个人造传导通路。人造传导通路的撤出可能有助于自我终止快速性心律失常，或者可能预处理快速性心律失常更有利于接受抗快速性心律失常治疗，如抗快速性心律失常起搏，除颤休克疗法或心脏复律。这可以帮助提供增强的抗慢性心律失常治疗。

88. 发明授权

US08480662B2 Systems and devices for photoablation 有权
公开(公告)号：US08480662B2
公开(公告)日：2013-07-09
申请号：US11895035
申请日：2007-08-22
申请人： Craig Stolen , Joseph M. Pastore , Robert J. Sweeney
发明人： Craig Stolen , Joseph M. Pastore , Robert J. Sweeney
IPC分类号： A61B18/18
CPC分类号： A61N5/062 , A61N5/0601 , A61N2005/063 , A61N2005/0651
摘要： The invention provides a catheter for optical ablation of tissue in a living body, the catheter including: a distal end; a proximal end; an elongate catheter body coupled between the distal end and the proximal end; a light emission device at the distal end and configured to emit an ablation light having characteristics selected to regulate an optically regulatable transcription control element operably linked to a nucleic acid sequence for a gene product, the expression of which gene product in cells directly or indirectly kills cells; and a projection control mechanism coupled to the light emission device and configured to control an effectively illuminated area where the optically regulatable transcription control element is effectively regulatable by the ablation light projected from the light emission device. Also provided is a system which includes the catheter, and methods to prevent, inhibit or treat AF which employ an expression cassette and/or one or more selected wavelengths of light.

89. 发明授权

US08385955B2 Permission based text messaging 有权
标题翻译：基于权限的短信
公开(公告)号：US08385955B2
公开(公告)日：2013-02-26
申请号：US13242581
申请日：2011-09-23
申请人： Robert J. Sweeney
发明人： Robert J. Sweeney
IPC分类号： H04W4/00 , H04L29/06 , H04M3/00
CPC分类号： H04W8/18 , H04L12/1859 , H04L51/38 , H04L63/101 , H04L67/26 , H04W4/06 , H04W4/12 , H04W4/14 , H04W12/06 , H04W12/08
摘要： A system and method for narrowcasting text messages to a plurality of cellular phones. The system and method allow a potential user to opt in to receive the text messages the user wants to receive. The potential user can opt in through a computer network based web page. Once the potential user sends a sign up request application to participate via the computer network, the user will receive a first text message containing an authorization code on their cell phone. The user enters the authorization code into the web page and sends the authorization code. Receipt of the authorization code back through the computer network will trigger the phone number of the potential user to be added to a list of authorized text message receivers. A narrowcaster then instructs the central computer to narrowcast text messages to the phone numbers on the list that have indicated they want to receive messages on a certain topic.
摘要翻译：一种用于将文本消息窄带化到多个蜂窝电话的系统和方法。系统和方法允许潜在用户选择接收用户想要接收的文本消息。潜在用户可以通过基于计算机网络的网页进行选择。一旦潜在用户通过计算机网络发送注册请求应用程序来参与，则用户将在其手机上接收到包含授权码的第一短信。用户将授权码输入网页并发送授权码。通过计算机网络接收授权码将触发要添加到授权文本消息接收者列表中的潜在用户的电话号码。然后，窄带指示器指示中央计算机将文本消息缩小到列表上已经表示希望在特定主题上接收消息的电话号码。

90. 发明申请

US20120245656A1 CONTROLLED TITRATION OF NEUROSTIMULATION THERAPY 有权
标题翻译：控制神经病治疗方法
公开(公告)号：US20120245656A1
公开(公告)日：2012-09-27
申请号：US13487877
申请日：2012-06-04
申请人： Marina V. Brockway , Imad Libbus , Krzysztof Z. Siejko , Robert J. Sweeney
发明人： Marina V. Brockway , Imad Libbus , Krzysztof Z. Siejko , Robert J. Sweeney
IPC分类号： A61N1/36
CPC分类号： A61N1/3727 , A61B5/02405 , A61B5/4035 , A61B5/4839 , A61N1/36114 , A61N1/36117 , A61N1/36139 , A61N1/362 , A61N1/37264
摘要： Described herein are methods and devices that utilize electrical neural stimulation to treat heart failure by modulating a patient's autonomic balance in a manner that inhibits sympathetic activity and/or augments parasympathetic activity. Because other therapies for treating heart failure may also affect a patient's autonomic balance, a device for delivering neural stimulation is configured to appropriately titrate such therapy in either an open-loop or closed-loop fashion.
摘要翻译：本文描述了利用电神经刺激来以抑制交感神经活动和/或增加副交感神经活动的方式调节患者的自主神经平衡来治疗心力衰竭的方法和装置。因为用于治疗心力衰竭的其它治疗也可能影响患者的自主平衡，用于递送神经刺激的装置被配置为以开环或闭环方式适当地滴定这种治疗。

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