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81. 发明公开

KR1020130037563A 한후박 추출물을 유효성분으로 함유하는 레티노익산 수용체의 활성화를 통한 항노화용 조성물 审中-实审
标题翻译：含有通过激活酸性受体来抗衰老的化学物质的组合物SIEBO ZUCCARINI的组合物
公开(公告)号：KR1020130037563A
公开(公告)日：2013-04-16
申请号：KR1020110102026
申请日：2011-10-06
申请人： (주)아모레퍼시픽
发明人： 강영규 , 박준성 , 조가영 , 나용주 , 박녹현 , 염명훈 , 조준철
IPC分类号： A61K36/57 , A61K36/48 , A61K8/97 , A61P17/00
摘要： PURPOSE: An antiaging composition containing a Machilus thunbergii extract an active ingredients through activation of a retinoic acid receptor is provided to suppress collagenase expression without side effects and to prevent skin aging. CONSTITUTION: An antiaging composition contains 0.0001-10 wt% of a Machilus thunbergii extract as an active ingredient. The extract is prepared using one or more solvents selected from the group consisting of anhydrous and hydrous C1-C4 alcohols, acetone, butylene glycol, ethyl acetate, diethyl acetate, diethyl ether, benzene, chloroform, and hexane. The composition further contains one or more extracts among 0.0001-10 wt% of a Rhynchosia nolubilis extract and 0.0001-10 wt% of a Glycine max (L.) Merr. extract as active ingredients.
摘要翻译：目的：提供通过活化视黄酸受体提取活性成分的含有马齿苋的抗衰老组合物，以抑制胶原酶的表达而无副作用并防止皮肤老化。构成：抗衰老组合物含有0.0001-10重量％的马齿苋提取物作为活性成分。使用一种或多种选自无水和含水C1-C4醇，丙酮，丁二醇，乙酸乙酯，乙酸二乙酯，乙醚，苯，氯仿和己烷的溶剂制备提取物。该组合物还包含0.0001-10重量％的蛇纹丝提取物和0.0001-10重量％的甘氨酸（L.）Merr中的一种或多种提取物。提取物作为活性成分。

82. 发明授权

KR101221212B1 항스트레스용 피부 화장료 조성물 有权
标题翻译：用于抑制由应激引起的皮肤麻烦的化妆品组合物
公开(公告)号：KR101221212B1
公开(公告)日：2013-01-11
申请号：KR1020050051308
申请日：2005-06-15
申请人： (주)아모레퍼시픽
发明人： 박녹현 , 박원석 , 전병배 , 황재성 , 장이섭
IPC分类号： A61K8/97 , A61Q19/00 , A61Q7/00
摘要： 본 발명은 시네올을 함유하는 항스트레스용 피부 화장료 조성물에 관한 것으로서, 보다 구체적으로는 스트레스에 의한 성장기 모낭이 퇴행기로 조기 이행되어 일어나는 탈모 현상을 시네올에 의해 효과적으로 저해시킴으로써 스트레스성 탈모 방지를 효과적으로 저해하는 항스트레스용 피부 화장료 조성물에 관한 것이다. 또한 본 발명에 의한 조성물은 미녹시딜, 판테놀 유도체, 백자인 및 당약추출물로 이루어진 군에서 선택된 1종 이상을 더 함유할 수 있다.
스트레스, 시네올, 탈모 방지, 화장료 조성물, 미녹시딜, 판테놀 유도체, 백자인, 당약추출물
摘要翻译：提供了用于抑制由应激引起的皮肤麻烦的化妆品组合物，以抑制由于从生长的毛囊的早期变化引起的由毛发诱导的退行性毛囊引起的毛发的损失。用于抑制由应激引起的皮肤麻烦的化妆品组合物包含1,8-桉树脑（2-氧杂双环[2,2,2]辛烷，1,3,3-三甲基-1,3,3,3-三甲基-2-氧杂双环[ 2,2,2]辛烷）作为有效成分，其中所述组合物进一步包含至少一种选自米诺地尔，泛醇衍生物，东方桐生物ENDL的组分。和中华假丝酵母（Bunge）Hara; 并且基于组合物的总重量，1,8-桉树脑的量为0.0001-10重量％，另外组分的量相对于组合物的总重量为0.001-10重量％。

83. 发明公开

KR1020130002308A 형질 전환 세포주와 백반증 마우스를 이용한 백모 방지 물질 스크리닝 방법 및 그 백모 방지 물질을 함유하는 백모방지용 조성물 有权
标题翻译：使用稳定的细胞系和加速的VITILIGO小鼠筛选抗灰霉素成分的方法，以及含有抗灰白色成分的组合物。
公开(公告)号：KR1020130002308A
公开(公告)日：2013-01-07
申请号：KR1020120151029
申请日：2012-12-21
申请人： (주)아모레퍼시픽
发明人： 민대진 , 박녹현 , 박원석 , 황재성 , 장이섭
IPC分类号： C12N15/63 , C12N15/85 , C12N5/10 , G01N33/15
摘要： PURPOSE: A method for screening a material which prevents gray hair using a transgenic cell line and vitiligo model mouse(C57bl/6-Mitfmi-vit) is provided to screen a PDE(phosphodiesterase) inhibitor as an anti-hair graying agent and to effectively prevent gray hair. CONSTITUTION: An expression vector pTRP2-GLuc contains: TRP2(tyrosinase-related protein 2) promoter; gaussia luciferase(GLuc); and neomycin resistant gene(NeoR) or ampicillin resistant gene(AmpR). A melan-a melanocyte cell line TRP2-GLuc (KCLRF-BP-00161) is prepared by transforming with the expression vector pTRP2-GLuc. A method for screening a material which prevents gray hair comprises: a step of treating the cell line with a candidate material which prevents gray hair and culturing; a step of measuring the production amount of GLuc in a medium; a step of applying the candidate material on the back of the vitiligo mouse; and a step of measuring the amount of melanin from grown hair on the back.
摘要翻译：目的：提供一种用于筛选使用转基因细胞系和白癜风模型小鼠（C57b1 / 6-Mitfmi-vit）防止灰白毛的材料的方法，以筛选PDE（磷酸二酯酶）抑制剂作为抗头发变灰剂并有效地防止灰发。构成：表达载体pTRP2-GLuc含有：TRP2（酪氨酸酶相关蛋白2）启动子; 高粱萤光素酶（GLuc）; 和新霉素抗性基因（NeoR）或氨苄青霉素抗性基因（AmpR）。通过用表达载体pTRP2-GLuc转化制备黑色素黑素细胞细胞系TRP2-GLuc（KCLRF-BP-00161）。用于筛选防止灰白毛发的材料的方法包括：用预防灰白毛发和培养的候选材料处理细胞系的步骤; 在培养基中测量GLuc的产生量的步骤; 将候选材料应用于白癜风小鼠背部的步骤; 以及测量背部生长的头发的黑色素的量的步骤。

84. 发明公开

KR1020110100393A 푸에라리아 속 식물 추출물 또는 푸에라린을 포함하는 백모 또는 백반증 예방 및 치료용 조성물 有权
标题翻译：用于防治和处理含有罂粟植物提取物或罂粟素的灰白色头发和白僵菌的组合物
公开(公告)号：KR1020110100393A
公开(公告)日：2011-09-14
申请号：KR1020100019346
申请日：2010-03-04
申请人： (주)아모레퍼시픽
发明人： 김형준 , 박원석 , 고현주 , 민대진 , 박녹현 , 박필준 , 김수나
IPC分类号： A61K8/97 , A61Q5/00 , A61Q19/00 , A61K36/48 , A61K36/488 , A61K31/7048 , A23L1/30
CPC分类号： A61K8/97 , A23L33/105 , A23V2002/00 , A23V2200/318 , A61K31/7048 , A61K36/48 , A61K36/488 , A61K2800/74 , A61Q5/00 , A61Q19/00
摘要： 본 발명은 푸에라리아(
Pueraria ) 속 식물 추출물 또는 푸에라린(puerarin)을 유효 성분으로 포함하여 백모 또는 백반증을 예방 및 치료하는 조성물을 개시한다.

85. 发明公开

KR1020110045662A 녹차 다당체 및 송이 버섯 추출물을 함유하는 항염 및 항산화용 화장료 조성물 有权
标题翻译：含有绿茶多糖和马铃薯提取物的抗炎和抗氧化的化妆品组合物
公开(公告)号：KR1020110045662A
公开(公告)日：2011-05-04
申请号：KR1020090102325
申请日：2009-10-27
申请人： (주)아모레퍼시픽
发明人： 강찬구 , 조성아 , 김지현 , 장희경 , 박녹현 , 조준철
IPC分类号： A61K8/73 , A61K8/97 , A61Q19/08 , A61Q19/00
CPC分类号： A61K36/07 , A61K8/73 , A61K8/97 , A61K36/82 , A61Q19/08 , A61K2300/00
摘要： PURPOSE: A cosmetic composition containing green tea polysaccharide and Tricholoma matsutake extract for antiaging is provided to promote aging due to UV ray and environmental pollution. CONSTITUTION: A cosmetic composition contains 0.01-20.0 weight% of green tea polysaccharide and Tricholoma matsutake extract in a mixture ratio of 1.0:10.0-10.0:1.0 as an active ingredient. The green tea polysaccharide is prepared by extracting green tea leaves at 80-90°C, concentrating, filtering to remove impurities, adding ethanol by dropwise, and performing hot wind drying.
摘要翻译：目的：提供一种含有绿茶多糖和抗秋水仙碱提取物的化妆品组合物，以促进由于紫外线和环境污染引起的老化。构成：作为活性成分，化妆品组合物含有0.01-20.0重量％的绿茶多糖和茯苓提取物，混合比为1.0:10.0-10.0:1.0。绿茶多糖通过在80-90℃下提取绿茶叶来制备，浓缩，过滤除去杂质，滴加乙醇，进行热风干燥。

86. 发明公开

KR1020100058858A 글루타밀아미도에틸 인돌을 함유하는 항노화용 화장료 조성물 有权
标题翻译：含有谷氨酰胺基吲哚的抗衰老化妆品组合物
公开(公告)号：KR1020100058858A
公开(公告)日：2010-06-04
申请号：KR1020080117419
申请日：2008-11-25
申请人： (주)아모레퍼시픽
发明人： 강찬구 , 임형준 , 김지영 , 조성아 , 김지현 , 박녹현 , 김용진 , 조준철 , 한상훈
IPC分类号： A61K8/49 , A61Q19/08
CPC分类号： A61K8/492 , A61K8/361 , A61K8/671 , A61Q19/08
摘要： PURPOSE: A cosmetic composition for anti-aging containing a glutamylamidoethyl indole is provided to regenerate and activate skin neural tissue. CONSTITUTION: A skin anti-aging cosmetic composition contains 0.001-1.0 weight% of glutamylamidoethy indole of chemical formula 1 as an active ingredient. The glutamylamidoethyl indole promotes synthesis of NFG(nerve growth factor). The skin anti-aging cosmetic composition additionally contains 0.001-10 weight% of leanolic acid, ursolic acid, glycyrrhetinic acid, or retinol.
摘要翻译：目的：提供含有谷氨酰胺基乙基吲哚的抗衰老化妆品组合物，以再生和激活皮肤神经组织。构成：皮肤抗衰老化妆品组合物含有0.001-1.0重量％的化学式1的谷氨酰氨基乙基吲哚作为活性成分。谷氨酰氨基乙基吲哚促进NFG（神经生长因子）的合成。皮肤抗衰老化妆品组合物另外含有0.001-10重量％的柠檬酸，熊果酸，甘草次酸或视黄醇。

87. 发明公开

KR1020100056200A 사삼, 고본 및 생약 추출물을 포함하는 것을 특징으로 하는화장료 조성물 有权
标题翻译：含有ADENOPHORA TRIPHYLLA VAR的提取物的化妆品组合物。 JAPONICA HARA，ANGELICA TENUISSIMA和CRUDE DRUGS
公开(公告)号：KR1020100056200A
公开(公告)日：2010-05-27
申请号：KR1020080115260
申请日：2008-11-19
申请人： (주)아모레퍼시픽
发明人： 박준성 , 김동현 , 박녹현 , 박혜윤 , 이재경 , 김덕희 , 김한곤
IPC分类号： A61K8/97 , A61Q19/00
CPC分类号： A61K8/97 , A61K2800/522 , A61Q19/00
摘要： PURPOSE: A cosmetic composition containing Adenophora triphylla var. japonica Hara, Angelica tenuissima Nakai, Ligusticum sinense Oliv, and herb extract is provided to ensure anti-oxidation and moisturization effects. CONSTITUTION: A cosmetic composition contains Adenophora triphylla var. japonica Hara, Angelica tenuissima Nakai, Ligusticum sinense Oliv, and herb extract as an active ingredient. The composition additionally contains Lycium chinense Mill. or Paeonia suffruticosa Andrews extract. The composition is obtained through a Milja method. The Milja method comprises: a step of diluting honey in warm water and spraying the honey water into medicinal herb materials; and a step of roasting the herb materials at 100-180°C for 10 minutes to one hour.
摘要翻译：目的：含有Adenophora triphylla var。粳稻，当归，中药，草药提取物，以确保抗氧化和保湿效果。构成：化妆品组合物含有三叶草（Adenophora triphylla var。粳稻，当归，中药，草药提取物作为活性成分。该组合物还含有枸杞子。或芍药安德鲁斯提取物。通过Milja方法获得组合物。 Milja方法包括：将蜂蜜在温水中稀释并将蜂蜜水喷洒到药材中的步骤; 并将草本材料在100-180℃下烘烤10分钟至1小时。

88. 发明授权

KR100953800B1 갈근을 함유하는 백모 방지용 및 백반증 치료용 조성물 有权
标题翻译：用于防止灰白色头发和用于治疗含白蛉的白斑病的组合物
公开(公告)号：KR100953800B1
公开(公告)日：2010-04-21
申请号：KR1020070119266
申请日：2007-11-21
申请人： (주)아모레퍼시픽
发明人： 박녹현 , 민대진 , 박원석 , 황재성 , 장이섭
IPC分类号： A61K36/488 , A61K8/97 , A61Q7/00
CPC分类号： A61K36/488
摘要： 본 발명은 갈근(칡)을 유효성분으로 함유하는 백모 방지용 및 백반증 치료용 조성물을 개시한다. 본 발명에 의한 백모 방지용 및 백반증 치료용 조성물은 멜라노사이트의 MITF 발현을 증가시켜 멜라노사이트를 활성화시키고 멜라닌 합성을 촉진함으로써 백모 방지와 백반증 치료를 도모한다.
갈근, 칡, 멜라노사이트, MITF, 멜라닌, 백모, 백반증

89. 发明公开

KR1020100037907A 녹차잎을 함유한 모발용 화장료 조성물 有权
标题翻译：具有绿茶叶的头发化妆品组合物
公开(公告)号：KR1020100037907A
公开(公告)日：2010-04-12
申请号：KR1020080097246
申请日：2008-10-02
申请人： (주)아모레퍼시픽
发明人： 문성호 , 민대진 , 박녹현 , 이존환 , 이기현 , 안수미
IPC分类号： A61K8/97 , A61Q5/00
CPC分类号： A61K8/97 , A61Q5/00
摘要： PURPOSE: A hair cosmetic composition containing water in which green tea leaves are brewed is provided to suppress itch of scalp and restore damaged hair. CONSTITUTION: A hair cosmetic composition contains 0.01-10.0 weight% of water in which green tea is brewed. The green tea water is extracted by infusing at low temperature. The green tea leaves are streamed and dried. The composition contains methylchloroisotiazolinone and methylisotiazolinone in methyl ρ-hydroxybenoate.
摘要翻译：目的：提供一种含有绿茶叶的水的头发化妆品组合物，以抑制头皮瘙痒并恢复损伤的头发。构成：头发化妆品组合物含有0.01-10.0重量％的酿造绿茶的水。绿茶水通过低温灌注而提取。绿茶叶被流出并干燥。该组合物在对羟基苯甲酸甲酯中含有甲基氯代噻唑啉酮和甲基异噻唑啉酮。

90. 发明公开

KR1020090129928A 인삼 꽃 추출물을 함유하는 피부 외용제 조성물 无效
标题翻译：组合物适用于金山花外用外用提取物
公开(公告)号：KR1020090129928A
公开(公告)日：2009-12-17
申请号：KR1020080124500
申请日：2008-12-09
申请人： (주)아모레퍼시픽
发明人： 염명훈 , 이진영 , 박녹현 , 박준성 , 김덕희 , 김한곤
IPC分类号： A61K8/97 , A61Q19/00
摘要： PURPOSE: A skin external composition containing ginseng flower extract is provided to prevent and treat dry skin and ensure anti-aging, anti-wrinkle, skin elasticity, whitening, and moisturization. CONSTITUTION: A skin external composition contains ginseng flower extract as an active ingredient. The ginseng flower extract is contained in 0.001-10 weight% based on total weight. A method for producing ginseng flower extract comprises: a step of adding organic solvent(ethanol, methanol, butanol, ether, ethylacetate, chloroform, etc) containing water to dried ginseng flower; a step of placing mixture at room temperature for one day; a step of removing chlorophyll; and a step of concentrating in vacuum condenser.
摘要翻译：目的：提供含有人参花提取物的皮肤外用组合物，用于预防和治疗干性皮肤，确保抗衰老，抗皱，皮肤弹性，美白和保湿。构成：皮肤外用组合物含有人参花提取物作为活性成分。人参花提取物的含量为0.001-10重量％。一种生产人参花提取物的方法包括：将含有水的有机溶剂（乙醇，甲醇，丁醇，乙醚，氯仿等）加入到人参花中的步骤; 将混合物在室温下放置一天的步骤; 去除叶绿素的步骤; 以及集中在真空冷凝器中的步骤。

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