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81. 发明授权

US11612587B2 Composition for preventing or treating hair loss 有权
公开(公告)号：US11612587B2
公开(公告)日：2023-03-28
申请号：US16975722
申请日：2019-02-19
申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人： Young Kwan Sung , Soon Sun Bak
IPC分类号： A61K31/407 , A23L29/00 , A61P17/14 , A61K8/49 , A61Q7/00
摘要： The present invention relates to a pharmaceutical composition for preventing or treating hair loss, a health functional food composition or a cosmetic composition, including a specific compound or a pharmaceutically acceptable salt thereof as an active ingredient, wherein the compound exhibits an excellent hair growth recovery effect in hair follicle tissues in which hair growth is inhibited without cytotoxicity, and thus hair loss can be more effectively prevented, improved, or treated.

82. 发明授权

US11481867B2 Device and method for registering three-dimensional data 有权
公开(公告)号：US11481867B2
公开(公告)日：2022-10-25
申请号：US16324886
申请日：2017-08-09
申请人： KOH YOUNG TECHNOLOGY INC. , KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人： Ki Hoon Kwon , Seung Hyun Lee , Min Young Kim
IPC分类号： G06T3/00 , G06T7/73
摘要： A method and a device for registering three-dimensional data are disclosed. The method for registering three-dimensional data comprises: generating first two-dimensional data by two-dimensionally converting first three-dimensional data indicating a surface of a three-dimensional model of a target, generating second two-dimensional data by two-dimensionally converting second three-dimensional data indicating at least a part of the three-dimensional surface of the target; determining a first matching region in the first two-dimensional data and a second matching region in the second two-dimensional data by matching the second two-dimensional data to the first two-dimensional data; setting, as initial position, a plurality of points of the first three-dimensional data, which correspond to the first matching region and a plurality of points of the second three-dimensional data, which correspond to the second matching region; and registering the first three-dimensional data and the second three-dimensional data using the initial position.

83. 发明申请

US20220283442A1 DEVICE AND METHOD FOR ACQUIRING MULTI-LUMINOSITY IMAGES 有权
公开(公告)号：US20220283442A1
公开(公告)日：2022-09-08
申请号：US17634709
申请日：2020-08-13
申请人： Kyungpook National University Industry-Academic Cooperation Foundation
发明人： Sung Hak LEE , Sun Gon JUN
IPC分类号： G02B27/10 , H04N5/225 , H04N5/235 , G02B5/20
摘要： The present invention relates to a device and a method for acquiring multi-luminosity images, wherein images having multiple luminosities in visible-ray and infrared wavelength domains can be captured and synthesized by using optical filter transmittance adjustment and infrared lighting strength adjustment. The device may comprise: a camera unit for photographing a predetermined subject and acquiring images thereof; a lighting unit disposed on the periphery of the camera unit, the lighting unit comprising a first infrared lamp for modulating and emitting infrared light according to the distance from the subject and a second infrared lamp for modulating and emitting infrared light according to the photography environment; an optical filter unit disposed on the front surface of the camera unit so as to adjust the amount of transmission of light directed to the camera unit; a lamp control unit for controlling the first infrared lamp such that infrared light is modulated on the basis of the distance from the subject; a luminosity multiplexing unit for producing a light multiplexing signal so as to control infrared light modulation by the second infrared lamp and the transmittance of the optical filter unit on the basis of the photography environment; and an image processing unit for synthesizing and processing multiple captured images.

84. 发明申请

US20220197077A1 FIELD OF VIEW AND COHERENCE ACTIVE CONTROL RANDOM REFRACTION DEVICE AND MANUFACTURING METHOD THEREFOR 有权
公开(公告)号：US20220197077A1
公开(公告)日：2022-06-23
申请号：US17692441
申请日：2022-03-11
申请人： Kyungpook National University Industry-Academic Cooperation Foundation
发明人： Hak-Rin Kim , Kyung-Il Joo , Tae-Hyun Lee , Min-Kyu Park
IPC分类号： G02F1/1347 , G02F1/01 , G02F1/1343 , G02F1/1335 , G02F1/1333 , G02F1/139
摘要： An active random refraction device includes a random structure having the same refractive index characteristics regardless of polarization direction of light, a liquid crystal polymer on the random structure with refractive index characteristics changing according to polarization direction of the light, a polarization switching device, and a refractive surface with an inclination angle randomly distributed along the horizontal direction perpendicular to the incident direction of the light. The active random refraction device can be switched between a transmission mode and a refractive mode according to the polarization of the light.

85. 发明授权

US11348251B2 Device and method for determining edge location based on adaptive weighing of gradients 有权
公开(公告)号：US11348251B2
公开(公告)日：2022-05-31
申请号：US16959527
申请日：2018-12-20
申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION
发明人： Suyoung Seo
IPC分类号： G06T7/13
摘要： Provided are a device and a method for determining an edge location based on the adaptive weighting of gradients (AWG). The method for determining an edge location according to an embodiment of the present invention includes the steps of determining, based on the edge width of an edge profile in an image, a power factor to be applied to a gradient of the edge profile in order to determine an edge location, calculating a difference value between values of adjacent pixels in the edge profile to generate the gradient, and applying the power factor determined based on the edge width to the gradient to determine the edge location.

86. 发明申请

US20220137138A1 DEVICE FOR DIAGNOSING TURN-SHORT FAULT OF INDUCTION MOTOR AND METHOD THEREOF 有权
公开(公告)号：US20220137138A1
公开(公告)日：2022-05-05
申请号：US17536430
申请日：2021-11-29
申请人： Kyungpook National University Industry-Academic Cooperation Foundation
发明人： Bon-Gwan Gu
IPC分类号： G01R31/34 , G01R31/52
摘要： A device for diagnosing a turn-short fault of an induction motor, the device including an induction motor; and a fault detecting unit to detect a current flowing in a supply line that supplies power to an input terminal of the induction motor and diagnose whether the induction motor has a fault, in which the fault detecting unit diagnoses whether the induction motor has the fault by applying a dynamic model. A method thereof is also disclosed.

87. 发明授权

US11280006B2 Method for preparing titanium-containing implant by using environmentally-friendly etching composition 有权
公开(公告)号：US11280006B2
公开(公告)日：2022-03-22
申请号：US15128735
申请日：2015-03-18
申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人： Kyo Han Kim , Tae Yub Kwon , Jun Sik Son
IPC分类号： C23F1/26 , A61L31/14 , A61L31/02 , A61L27/06 , C23F1/00
摘要： The present invention provides a method for preparing an implant including preparing a mixed etching composition including hydrogen peroxide and a water-soluble carbonate compound and oxidatively etching an implant made of titanium or a titanium alloy by immersing the same in the etching composition; a titanium or titanium alloy implant prepared by oxidative etching with a mixed etching composition including hydrogen peroxide and a water-soluble carbonate compound; and a composition for treating surface of an implant containing hydrogen peroxide and a water-soluble carbonate compound. Further, the present invention relates to a titanium or titanium alloy implant which is prepared by oxidative etching with a mixed etching composition including hydrogen peroxide and a basic solution and on which surface bumps having continuous or discontinuous line-shaped open channel structures in nanoscale are irregularly formed, and a preparation method thereof. The surface of the titanium alloys treated with the mixed etching composition including hydrogen peroxide and a carbonate compound or the etching composition containing hydrogen peroxide and a basic solution of the present invention includes micrometer-sized bumps and channel-shaped nanometer-sized bumps, and thus has an increased surface area, and can not only improve wettability, but also effectively promote cell proliferation and osteocyte differentiation. In addition, the composition includes no chemical compounds such as a strong acid, etc. and is thus environmentally friendly, and such compounds can be prevented from remaining on the surface, which can improve biocompatibility, and therefore, the composition can be useful for implant surface treatment.

88. 发明授权

US11279744B2 Neuropeptide Y fragment capable of releasing hematopoietic stem cells into blood and treating osteoporosis 有权
公开(公告)号：US11279744B2
公开(公告)日：2022-03-22
申请号：US16733347
申请日：2020-01-03
申请人： Kyungpook National University Industry-Academic Cooperation Foundation
发明人： Jae Sung Bae , Hee Kyung Jin , Min Hee Park
IPC分类号： C07K14/575 , A23L33/18 , A61P19/10 , A61K38/00
摘要： The present invention relates to a novel peptide exhibiting an effect of releasing myelopoiesis stem cells into blood and an osteoporosis therapeutic effect and use thereof and, in particularly, to a novel peptide consisting of an amino acid sequence of SEQ. ID.NO:1 which has effects of releasing hematopoietic stem cells into a bloodstream and decreasing osteoclast cells in bone narrow, and a pharmaceutical composition comprising the novel peptide as an active ingredient for preventing or treating neutropenia, anemia or osteoporosis. Because of side effects, the peptide of the present invention not only increases level of leukocytes, red blood cells and platelets in blood, but also alleviates a decrease in bone density, and therefore, can be very usefully used for the development of a prophylactic or therapeutic agent for neutropenia, anemia or osteoporosis.

89. 发明授权

US11266755B2 Development and application of tumor diagnostic radioactive probe targeting folic acid receptor 有权
公开(公告)号：US11266755B2
公开(公告)日：2022-03-08
申请号：US16700629
申请日：2019-12-02
申请人： Kyungpook National University Industry-Academic Cooperation Foundation
发明人： Jeong Soo Yoo , Woong Hee Lee
IPC分类号： A61K51/00 , A61M36/14 , A61K51/12 , A61B5/00 , A61B6/03 , A61K49/00
摘要： The present invention pertains to a novel liposome-based contrast agent that is for suppressing absorption in the reticuloendothelial system and for tumor-specific delivery of a radiolabeled substance. More specifically, the present invention pertains to: a liposome contrast agent containing a lipid and a compound of chemical formula 1, which is a radiolabeled substance, the liposome contrast agent being characterized in that the lipid is composed of (a) cholesterol, (b) 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and (c) 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N [methoxy(polyethylene glycol)-2000] (DSPE-PEG2000); and a cancer diagnostic composition containing the liposome contrast agent as an active ingredient. If a liposome system, containing a contrast substance of chemical formula 1 having a unique lipid composition provided by the present invention, is manufactured, the tumor-to-organ uptake ratio of the contrast substance in the reticuloendothelial system increases significantly, thus greatly increasing the tumor diagnostic efficiency of the compound of chemical formula 1.

90. 发明授权

US11242529B2 Method for treating a neurological disorder comprising administering ASM inhibitors 有权
公开(公告)号：US11242529B2
公开(公告)日：2022-02-08
申请号：US16863942
申请日：2020-04-30
申请人： KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION
发明人： Jae Sung Bae , Hee Kyung Jin , Min Hee Park
IPC分类号： A61K48/00 , C12N15/113 , A61P25/24 , A61K38/00 , A61K31/7105 , A61K31/713
摘要： The present invention relates to a method for treating degenerative neurological disorders in a subject in need thereof, comprising administering to a subject in need thereof a therapeutically effective amount of a composition comprising an acid sphingomyelinase (ASM) activity inhibitor or expression inhibitor as an active ingredient.

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