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81. 发明授权

US07090090B2 Container for microwave oven cooking 失效
标题翻译：用于微波炉烹饪的容器
公开(公告)号：US07090090B2
公开(公告)日：2006-08-15
申请号：US10806200
申请日：2004-03-22
申请人： Yoshio Ohyama
发明人： Yoshio Ohyama
IPC分类号： B65D51/16
CPC分类号： B65D43/021 , A47J36/027 , B65D21/0237 , B65D81/3453 , B65D2543/00092 , B65D2543/00296 , B65D2543/00351 , B65D2543/00509 , B65D2543/00546 , B65D2543/0062 , B65D2543/00685 , B65D2543/00731 , B65D2543/00796
摘要： A container system for microwave oven cooking comprises a main body, a lid, and a cap disposed in a recess in the lid. The cap is movable upward and downward through a limited range in the recess depending on steam pressure, and grooves, formed in a side wall of the cap, or in a side wall of the recess, allow escape of steam when the cap is moved upward as a result of steam pressure. The lid is also allowed to move upward and downward relative to the main container body in response to steam pressure, and, when the lid is moved upward, an additional path for the escape of stem is provided at the location where the rims of the lid and main body meet each other.
摘要翻译：用于微波炉烹饪的容器系统包括设置在盖中的凹部中的主体，盖和盖。盖子可以根据蒸汽压力在凹部中的上下有限的范围内移动，并且形成在盖的侧壁中或在凹槽的侧壁中的槽允许当帽向上移动时蒸汽逸出由于蒸汽压力。盖子还可以响应于蒸汽压力而相对于主容器主体上下移动，并且当盖子向上移动时，在盖子的边缘的位置处设置用于杆的逸出的附加路径和主体相遇。

82. 发明授权

US07081457B2 Cyclothiocarbamate derivatives as progesterone receptor modulators 失效
标题翻译：环硫代氨基甲酸酯衍生物作为孕酮受体调节剂
公开(公告)号：US07081457B2
公开(公告)日：2006-07-25
申请号：US10140034
申请日：2002-05-06
申请人： Puwen Zhang , Andrew Fensome , Eugene A. Terefenko , Lin Zhi , Todd K. Jones , James P. Edwards , Christopher M. Tegley , Jay E. Wrobel , Mark A. Collins
发明人： Puwen Zhang , Andrew Fensome , Eugene A. Terefenko , Lin Zhi , Todd K. Jones , James P. Edwards , Christopher M. Tegley , Jay E. Wrobel , Mark A. Collins
IPC分类号： A61K31/535 , C07D295/00 , C07D265/12
CPC分类号： A61K31/536 , A61K31/538 , C07D265/18 , C07D413/04
摘要： Methods of using compounds which are progesterone receptor agonists for contraception and the treatment of progesterone-related maladies alone or in combination with an estrogen receptor agonist or progesterone receptor antagonist are provided. These compounds have the structure: wherein R1 and R2 are selected from the group of H, optionally substituted C1 to C6 alkyl, alkenyl, alkynyl, or alkynyl groups C3 to C8 cycloalkyl, aryl, substituted aryl, or heterocyclic groups, or CORA or NRBCORA; or R1 and R2 are fused to form an optionally substituted ring structure as defined herein; RA and RB are as defined herein; R3 is H, OH, NH2, CORC, or optionally substituted C1 to C6 alkyl, C3 to C6 alkenyl, or alkynyl groups; RC is as defined herein; Q1 is S, NR7, or CR8R9; R5 is an optionally trisubstituted benzene ring or an optionally substituted five or six membered heterocyclic ring.
摘要翻译：提供使用孕酮受体激动剂用于避孕的化合物和单独或与雌激素受体激动剂或孕酮受体拮抗剂联合治疗孕激素相关性疾病的方法。这些化合物具有以下结构：其中R 1和R 2选自H，任选取代的C 1至C 1 - C 6烷基，链烯基，炔基或炔基C 3至C 8环烷基，芳基，取代的芳基或杂环基，或COR A 或或 B 或R 1和R 2 2稠合形成如本文所定义的任选取代的环结构; R＆lt; A＆gt;和＆lt; B＆gt; B＆gt;如本文所定义; R 3是H，OH，NH 2，COR C或任选取代的C 1至C

83. 发明授权

US07077774B2 Roller chain transmission device 有权
标题翻译：滚筒链传动装置
公开(公告)号：US07077774B2
公开(公告)日：2006-07-18
申请号：US10774020
申请日：2004-02-06
申请人： Isamu Okabe , Tomotaka Koga
发明人： Isamu Okabe , Tomotaka Koga
IPC分类号： F16G13/06
CPC分类号： F16G13/06
摘要： In a roller chain transmission, the diameter D of the rollers, the outer diameter d of the pins, and the height H of the inner plates satisfy the relationships 0.72P≦D≦0.79P, 0.40P≦d≦0.44P, and 0.96P≦H, with respect to the chain pitch P. The radius r of the arc of the tooth gap bottom of the sprocket teeth satisfies the relationship 0.505D≦r≦0.505D+0.069{square root over (D)}. The transmission chain exhibits high durability due to improved strength and wear resistance under high loads.
摘要翻译：在滚子链传动装置中，辊的直径D，销的外径d和内板的高度H满足关系0.72P <= D <= 0.79P，0.40P <= d <= 0.44 P和0.96P <= H，相对于链节距P.链齿的齿隙底部的弧的半径r满足关系0.505D <= r <= 0.505D + 0.069 {平方根超过（D.由于在高负载下提高强度和耐磨性，传动链表现出高耐用性。

84. 发明授权

US07058985B2 Ear covering and manufacturing method 失效
标题翻译：耳罩和制造方法
公开(公告)号：US07058985B2
公开(公告)日：2006-06-13
申请号：US11122437
申请日：2005-05-05
申请人： Masao Tanaka
发明人： Masao Tanaka
IPC分类号： A42B1/00
CPC分类号： A61F11/14
摘要： An ear covering is produced by sewing first and second cloth layers together along a first closed loop seam, and forming a hole inside the loop and extending through both layers; turning the sewn first and second layers inside out by passing one layer through the opening; then passing one of the layers through a passage in a flexible insert in the form of a distorted, truncated cone; placing a third cloth layer over one of the first and second layers and sewing the first second and third cloth layers along a second closed-loop seam, thereby enclosing the insert within a toroidal enclosure formed by portions of the first and second layers. Afterwards, the assembly is turned inside out to form a cup-shaped receptacle for receiving an external ear, with the second seam in the interior of the receptacle, and with the first seam within the toroidal enclosure.
摘要翻译：通过将第一和第二布层沿着第一闭环接缝缝合在一起，并在环内形成一个孔并延伸穿过两个层来产生耳罩。通过将一层通过开口将缝合的第一层和第二层内侧翻开; 然后使其中的一层穿过柔性插入件中的通道，其形式为扭曲的截头锥体; 将第三布层放置在第一层和第二层之一上，并沿着第二闭环接缝缝合第一第二和第三布层，从而将插入件封闭在由第一层和第二层的部分形成的环形外壳内。之后，将组件向内转出，形成用于容纳外耳的杯状容器，其中第二接缝位于容器内部，并且第一接缝在环形外壳内。

85. 发明授权

US07056502B2 Recombinant aav vectors with AAV5 capsids and AAV5 vectors pseudotyped in heterologous capsids 失效
标题翻译：具有AAV5衣壳的重组aav载体和在异源衣壳中假型的AAV5载体
公开(公告)号：US07056502B2
公开(公告)日：2006-06-06
申请号：US10257961
申请日：2001-04-23
申请人： Markus Hildinger , James M. Wilson , Alberto Auricchio
发明人： Markus Hildinger , James M. Wilson , Alberto Auricchio
IPC分类号： A61K48/00 , C12N15/864
CPC分类号： C12N15/86 , A61K48/00 , C12N7/00 , C12N2750/14122 , C12N2750/14143 , C12N2750/14145 , C12N2750/14162 , C12N2830/008 , C12N2830/48
摘要： A pseudotyped rAAV is described, which contains sequences derived from AAV5. A method for producing rAAV pseudotyped with AAV5 capsid is described in which the rep proteins of the serotype or any cross-reactive serotype of the AAV ITRs are utilized. A similar method may be provided to generate a pseudotyped rAAV in which minigenes carrying AAV5 ITRs are packaged in capsids of a heterologous AAV serotype. Also provided are pharmaceutical compositions containing the pseudotyped rAAV and methods of using them for gene delivery.
摘要翻译：描述了一种假型rAAV，其包含衍生自AAV5的序列。描述了用AAV5衣壳制备rAAV假型的方法，其中使用AAV ITR的血清型或任何交叉反应性血清型的rep蛋白。可以提供类似的方法来产生假型rAAV，其中将携带AAV5 ITR的小基因包装在异源AAV血清型的衣壳中。还提供了含有假型rAAV的药物组合物及其用于基因递送的方法。

86. 发明授权

US07022497B1 Human kallikrein-like genes 失效
标题翻译：人类激肽释放酶样基因
公开(公告)号：US07022497B1
公开(公告)日：2006-04-04
申请号：US09936271
申请日：2000-03-09
申请人： George M. Yousef , Eleftherios P. Diamandis
发明人： George M. Yousef , Eleftherios P. Diamandis
IPC分类号： C12N15/00
CPC分类号： C07K14/705 , C12N9/6445
摘要： The invention relates to nucleic acid molecules, kallikrein-like proteins encoded by such nucleic acid molecules; and use of the proteins and nucleic acid molecules.
摘要翻译：本发明涉及由核酸分子编码的核酸分子，激肽释放酶样蛋白; 并使用蛋白质和核酸分子。

87. 发明授权

US06994644B2 Tensioner 失效
标题翻译：张紧器
公开(公告)号：US06994644B2
公开(公告)日：2006-02-07
申请号：US10620753
申请日：2003-07-16
申请人： Osamu Yoshida , Hiroshi Hashimoto
发明人： Osamu Yoshida , Hiroshi Hashimoto
IPC分类号： E16H7/08
CPC分类号： F16H7/0848 , F16H2007/0806 , F16H2007/0812 , F16H2007/0853 , F16H2007/0859
摘要： In a chain tensioner comprising a plunger having toothed racks engageable with wedge-shaped cams which cooperate with oblique cam-guiding surfaces, the cam-guiding surfaces are formed on a cam-receiving ring disposed in an enlarged part of the cam-receiving hole adjacent the front end of the tensioner housing, and axially movable, through a limited distance, in a space between a shoulder and a seal cap. The axially movable cam-receiving ring increases both the minimum and maximum backlash distances of the plunger, thereby making it possible for the tensioner to accommodate different chain conditions by changing the axial dimensions of the cam-receiving ring, or the space in which it moves, instead of, or in addition to, modifying the angle of the cam-guiding surfaces.
摘要翻译：在具有可与楔形凸轮啮合的齿形齿条的活塞的链条张紧器中，所述楔形凸轮与倾斜凸轮引导表面配合，凸轮引导表面形成在凸轮接收环上，所述凸轮接收环设置在相邻的凸轮接收孔的扩大部分中张紧器壳体的前端，并且在肩部和密封帽之间的空间中可轴向移动，限制距离。轴向可移动的凸轮接收环增加柱塞的最小和最大间隙距离，从而使得张紧器可以通过改变凸轮接收环的轴向尺寸或其移动的空间来适应不同的链条条件，而不是或改变凸轮引导表面的角度。

88. 发明授权

US06969795B2 Electronic tone generation system and batons therefor 有权
公开(公告)号：US06969795B2
公开(公告)日：2005-11-29
申请号：US10706803
申请日：2003-11-12
申请人： Mark R. Hofmeister , Gregory L. Schwartz
发明人： Mark R. Hofmeister , Gregory L. Schwartz
IPC分类号： G10D20060101 , G10G1/00 , G10H1/055 , G10H3/00 , G10H7/00
CPC分类号： G10H1/0556 , G10H2220/206 , G10H2220/395 , G10H2220/525 , G10H2240/211
摘要： An electronic tone generation system including a plurality of separate, portable, handheld transmitters, or batons, that are provided as “instruments” to numerous players to form a choir. Each baton is activated by one of the players to send a signal, preferably a wireless signal, to a single receiver which produces an output signal fed to a tone generator, preferably a MIDI tone generator, which produces audible sounds via an amplifier and speakers. For example, the batons can correspond to different musical notes as played by a selected musical instrument and the batons can be played in concert by the choir to produce a musical or other audible presentation. Alternatively, selected batons can be designated to play in one voice, while others batons are set to play other voices.

89. 发明授权

US06953690B1 Compositions and methods for helper-free production of recombinant adeno-associated viruses 有权
标题翻译：无辅助生产重组腺相关病毒的组合物和方法
公开(公告)号：US06953690B1
公开(公告)日：2005-10-11
申请号：US09665852
申请日：2000-09-20
申请人： Guangping Gao , James M. Wilson
发明人： Guangping Gao , James M. Wilson
IPC分类号： A01N63/00 , A61K48/00 , C07H21/04 , C12N5/00 , C12N5/10 , C12N7/02 , C12N15/00 , C12N15/86 , C12N15/864
CPC分类号： C12N7/00 , A61K48/0091 , C07H21/04 , C12N15/86 , C12N2510/02 , C12N2750/14143 , C12N2750/14151 , C12N2750/14152 , C12N2830/002 , C12N2830/003 , C12N2830/006 , C12N2830/008 , C12N2830/60
摘要： A method for producing recombinant adeno-associated virus in the absence of contaminating helper virus or wild-type virus involves culturing a mammalian host cell containing a transgene flanked by adeno-associated virus (AAV) inverse terminal repeats and under the control of regulatory sequences directing expression thereof, an AAV rep sequence and an AAV cap sequence under the control of regulatory sequences directing expression thereof, and the minimum adenovirus DNA required to express an E1a gene product, an E1b gene product and an E2a gene product, and isolating therefrom a recombinant AAV which expresses the transgene in the absence of contaminating helper virus or wildtype AAV. This method obviates a subsequent purification step to purify rAAV from contaminating virus. Also provided are various embodiments of the host cell.
摘要翻译：在不存在污染性辅助病毒或野生型病毒的情况下，用于产生重组腺相关病毒的方法包括培养含有侧翼为腺相关病毒（AAV）反末端重复的转基因的哺乳动物宿主细胞，并在调控序列指导其表达，AAV rep序列和AAV cap序列，以及引导其表达的调节序列的控制，以及表达E1a基因产物所需的最小腺病毒DNA，E1b基因产物和E2a基因产物，并从其中分离重组在没有污染性辅助病毒或野生型AAV的情况下表达转基因的AAV。该方法避免了随后的纯化步骤以从污染病毒中纯化rAAV。还提供了宿主细胞的各种实施方案。

90. 发明授权

US06952000B2 Rice cooking system for microwave oven 失效
标题翻译：微波炉炒饭系统
公开(公告)号：US06952000B2
公开(公告)日：2005-10-04
申请号：US10901522
申请日：2004-07-28
申请人： Yoshio Ohyama
发明人： Yoshio Ohyama
IPC分类号： A47J27/00 , A23L5/10 , A23L7/10 , A47J27/02 , A47J27/04 , A47J36/02 , H05B6/80
CPC分类号： A47J36/027 , A47J27/04 , Y10S99/14
摘要： A rice cooking system for a microwave oven comprises an inner cooking container for containing rice and rice cooking water, main outer container holding the inner container with a space in between their side surfaces, a lid covering the outer container, and a foam control sheet having a plurality of small holes 52 and supported between the outer container and the lid. The inner cooking container is made of metal and has a folded or rolled a rim. A step at the bottom of the outer container locates the inner cooking container so that its outer wall is spaced from the outer container.
摘要翻译：一种用于微波炉的炊事烹饪系统包括：用于容纳米饭烹饪水的内部烹饪容器，在其侧表面之间保持内部容器的空间的主外部容器，覆盖外部容器的盖子和具有多个小孔52并被支撑在外部容器和盖子之间。内部烹饪容器由金属制成并具有折叠或滚动的边缘。外容器底部的台阶位于内部烹饪容器中，使其外壁与外部容器间隔开。

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