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71. 发明申请

US20040147041A1 Examination device and method for examination of chemical and/or biological samples 失效
标题翻译：化学和/或生物样品的检查装置和方法
公开(公告)号：US20040147041A1
公开(公告)日：2004-07-29
申请号：US10472132
申请日：2004-03-08
发明人： Andreas Bosio
IPC分类号： G01N001/00
CPC分类号： G01N1/312 , Y10T436/113332 , Y10T436/25
摘要： An analyzing device for analyzing chemical and/or biological samples comprises a plurality of base parts (12), e.g. object holders, in a receiving device (10). Said base parts (12) are closed by a lid (26) which is configured such that each base part (12) and the lid (26) form a test chamber (38) for receiving the sample. Further, a conveying means (46,50;68) for moving the sample in the test chamber (38) is provided. The pumps (46,50) of the conveying means are connected via channels (40,42) with the test chamber and are controlled such that a portion of the sample liquid is alternately drawn off the test chamber (38) and supplied back thereto by the pumps (46,50).

72. 发明申请

US20040132205A1 Method and apparatus for aligning microbeads in order to interrogate the same 有权
标题翻译：用于对准微珠以便询问它的方法和装置
公开(公告)号：US20040132205A1
公开(公告)日：2004-07-08
申请号：US10661836
申请日：2003-09-12
发明人： John Moon , Martin A. Putnam , Tuo Li , Joseph Traynor
IPC分类号： G01N001/00
CPC分类号： G03H1/0272 , B01J2219/00459 , B01J2219/00463 , B01J2219/0047 , B01J2219/005 , B01J2219/00547 , B01J2219/00576 , B01J2219/00702 , B01L3/502761 , B01L3/5085 , B01L2200/0636 , B01L2200/0668 , B01L2300/0654 , B01L2400/0409 , B01L2400/0457 , B01L2400/0487 , G03H2210/53 , G03H2230/10 , G03H2270/20 , G03H2270/24 , Y10T436/25
摘要： A method and apparatus are provided for aligning optical elements or microbeads, wherein each microbead has an elongated body with a code embedded therein along a longitudinal axis thereof to be read by a code reading device. The microbeads are aligned with a positioning device so the longitudinal axis of the microbeads is positioned in a fixed orientation relative to the code reading device. The microbeads are typically cylindrically shaped glass beads between 25 and 250 microns (nullm) in diameter and between 100 and 500 nullm long, and have a holographic code embedded in the central region of the bead, which is used to identify it from the rest of the beads in a batch of beads with many different chemical probes. A cross reference is used to determine which probe is attached to which bead, thus allowing the researcher to correlate the chemical content on each bead with the measured fluorescence signal. Because the code consists of a diffraction grating typically disposed along an axis, there is a particular alignment required between the incident readout laser beam and the readout detector in two of the three rotational axes. The third axis, rotation about the center axis of the cylinder, is azimuthally symmetric and therefore does not require alignment.
摘要翻译：提供了一种用于对准光学元件或微珠的方法和装置，其中每个微珠具有细长体，其沿着其纵向轴线嵌入其中的代码，以被代码读取装置读取。微珠与定位装置对准，使得微珠的纵向轴线相对于代码读取装置定位成固定的取向。微珠通常为直径为25至250微米（母体）和长度为100至500毫米的圆柱形玻璃珠，并且具有嵌入珠的中心区域中的全息代码，其用于从其余部分识别它珠子中有一批具有许多不同化学探针的珠粒。交叉参考用于确定哪个探针连接到哪个珠，从而允许研究者将每个珠上的化学成分与测量的荧光信号相关联。由于代码由通常沿轴线设置的衍射光栅组成，因此在三个旋转轴中的两个中存在入射读出激光束和读出检测器之间所需的特定对准。第三轴，围绕气缸的中心轴的旋转是方位对称的，因此不需要对准。

73. 发明申请

US20040103727A1 Method for supplying an internal combustion engine with conditioned combustion gas, device for carrying out said method, method for determining the quantities of pollutants in the exhaust gases of an internal combustion engine, and device for carrying out said method 有权
公开(公告)号：US20040103727A1
公开(公告)日：2004-06-03
申请号：US10432393
申请日：2003-11-10
发明人： Hans Erlach , Johann Simperl
IPC分类号： G01N001/00
CPC分类号： G01M15/102 , F02B3/06 , F02B29/0437 , F02B29/0468 , F02B29/0493 , F02B43/00 , F02B47/02 , F02D23/02 , F02M25/0227 , F02M25/035 , F02M31/00 , Y02T10/121 , Y02T10/126 , Y02T10/146 , Y02T10/32
摘要： The invention relates to a method for supplying an internal combustion engine with conditioned combustion gas, involving the supply of humidity and/or temperature-conditioned combustion gas. The aim of this method is to largely enable the combustion air to be reliably and constantly conditioned even in dynamic operating conditions. To this end, an essentially constant and fully conditioned quantity of combustion gas is provided at each instant, said quantity corresponding to at least the maximum quantity required by the respective internal combustion engine. The invention also relates to a method for determining the quantities of pollutants in the exhaust gases of an internal combustion engine by diluting the exhaust gases using a diluent gas of a known composition. In order to enable the exhaust gases to be diluted in a precisely defined manner, and thus to precisely determine the quantities of pollutants, simply and reliably, an essentially constant and fully conditioned quantity of humidity and/or temperature-conditioned combustion gas is supplied at each instant, said quantity corresponding to at least the maximum quantity required by the respective internal combustion engine, and the exhaust gases are diluted with the quantity of combustion gas which is not used by the internal combustion engine. The invention also relates to devices for carrying out the two methods cited, each comprising a supply line (15) to the internal combustion engine (1), for the humidity and/or temperature-conditioned combustion gas, at least one measuring point (30) for determining the concentration of pollutants, and a determination device (32, 33; 41, 42) for the flow of a gas, said determination device comprising a passage (15) for a diluent gas of a known composition. Said devices are characterised in that the supply line or supply passage (15) is designed for at least the maximum quantity of combustion gas required by the respective internal combustion engine (1), and a suction pipe (2) which can be connected to the internal combustion engine (1) branches off from said supply line (15).

74. 发明申请

US20040083827A1 Lysimeter methods and apparatus 失效
公开(公告)号：US20040083827A1
公开(公告)日：2004-05-06
申请号：US10285798
申请日：2002-10-31
发明人： Don T. Clark , Eugene E. Erickson , William L. Casper , David M. Everett , Joel M. Hubbell , James B. Sisson
IPC分类号： G01N001/00 , G01N001/04
CPC分类号： E21B49/084 , E02D1/06 , G01N1/14 , G01N33/246
摘要： A suction lysimeter for sampling subsurface liquids includes a lysimeter casing having a drive portion, a reservoir portion, and a tip portion, the tip portion including a membrane through which subsurface liquids may be sampled; a fluid conduit coupled in fluid flowing relation relative to the membrane, and which in operation facilitates the delivery of the sampled subsurface liquids from the membrane to the reservoir portion; and a plurality of tubes coupled in fluid flowing relation relative to the reservoir portion, the tubes in operation facilitating delivery of the sampled subsurface liquids from the reservoir portion for testing. A method of sampling subsurface liquids comprises using this lysimeter.

75. 发明申请

US20040077092A1 Control and calibration material for blood coagulation tests 审中-公开
标题翻译：用于血液凝固试验的控制和校准材料
公开(公告)号：US20040077092A1
公开(公告)日：2004-04-22
申请号：US10437827
申请日：2003-05-14
发明人： Hans Wielinger , Rainer Fuellemann , Erika Abel
IPC分类号： G01N001/00
CPC分类号： G01N33/86 , Y10T436/101666
摘要： Control and calibration material for blood coagulation tests The invention concerns control and calibration materials for coagulation tests which contain plasma and a substance or a mixture of substances which prolongs the clotting time of the plasma.
摘要翻译：用于血液凝固测试的控制和校准材料本发明涉及用于凝血试验的控制和校准材料，其包含血浆以及延长血浆凝血时间的物质或物质混合物。

76. 发明申请

US20040071604A1 Container for reagents for the analysis by various analytical methods,method for producing a measuring vessel, measuring vessel and use of said measuring vessel 审中-公开
标题翻译：用于通过各种分析方法进行分析的试剂的容器，用于生产测量容器的方法，测量容器和所述测量容器的使用
公开(公告)号：US20040071604A1
公开(公告)日：2004-04-15
申请号：US10468974
申请日：2003-08-22
发明人： Hans-J?uuml;rgen Kolde , Holger Eggert
IPC分类号： B01L003/00 , G01N001/00
CPC分类号： B01L3/545 , Y10T436/25
摘要： A container (1) is provided, which serves as reagent support and measuring vessel for analysis using various analytical processes, and has a region which is divided into at least two chambers (9a, 9b, 9c) by one or more bars (8) extending from the container wall (5) or the container base (4), wherein the chambers are arranged so that liquid or solid reagents may be introduced therein without them being able to be mixed by diffusion or running into one another. The container is used for drying or freeze-drying by with completely or partly filled chambers and serves at the same time as a measuring vessel after re-dissolving the dried material by adding water, reagent solution, or the sample present in aqueous phase.
摘要翻译：提供容器（1），其用作用于使用各种分析过程进行分析的试剂载体和测量容器，并且具有通过一个或多个条（8）分成至少两个室（9a，9b，9c）的区域，从容器壁（5）或容器底座（4）延伸出来，其中所述室被布置成使得液体或固体试剂可以被引入其中，而不能通过扩散或彼此流动混合。该容器通过完全或部分填充的室用于干燥或冷冻干燥，并通过加入水，试剂溶液或存在于水相中的样品再次溶解干燥的材料而与测量容器同时工作。

77. 发明申请

US20040065158A1 Method and device for determining the concentration of a substance in body liquid 有权
标题翻译：用于测定体液中物质浓度的方法和装置
公开(公告)号：US20040065158A1
公开(公告)日：2004-04-08
申请号：US09980661
申请日：2003-10-02
发明人： Thomas W. Schrepfer , Andreas Caduff , Etienne Hirt , Heinz Susstrunk
IPC分类号： G01N001/00
CPC分类号： A61B5/05 , A61B5/053 , A61B5/14532
摘要： For measuring the concentration of a substance in body fluid, such as the glucose level in blood or tissue, a strip electrode (18) and a ring electrode (19) are arranged at the specimen. The ring electrode (19) is in direct electrical contact with the specimen while the strip electrode (18) is electrically insulated therefrom. The strip electrode (18) is arranged parallel to an arm or a leg for obtaining a large interaction length. The electrodes (18, 19) form a capacitor in a resonant circuit. A modulated voltage in the MHz range close to or at the resonance frequency is applied to the electrodes and the response of the body fluid is measured. This design allows a measurement of high accuracy.
摘要翻译：为了测量体液中物质的浓度，例如血液或组织中的葡萄糖水平，在样品上布置带状电极（18）和环形电极（19）。环状电极（19）与样品直接电接触，而带状电极（18）与其电绝缘。带状电极（18）平行于臂或腿布置以获得大的相互作用长度。电极（18,19）在谐振电路中形成电容器。接近或谐振频率的MHz范围内的调制电压被施加到电极，并且测量体液的响应。该设计允许测量高精度。

78. 发明申请

US20040022687A1 Device and process for collecting and releasing saliva 审中-公开
标题翻译：用于收集和释放唾液的装置和过程
公开(公告)号：US20040022687A1
公开(公告)日：2004-02-05
申请号：US10417646
申请日：2003-04-17
发明人： Thomas Wuske , Torben Bauch , Rainer Polzius , Jessica Mahn
IPC分类号： B01L011/00 , G01N001/00
CPC分类号： B01L3/5029 , A61B10/0051 , A61B10/0096 , B01L3/508 , B01L2300/0681 , B01L2400/0481 , G01N1/12 , G01N2001/1056 , G01N2001/149 , Y10T436/25
摘要： A device for collecting and releasing a sample liquid, especially saliva as well as a system and method are provided. The device and system obtains and provides a defined saliva sample, i.e., a filtered and homogeneously mixed saliva sample of a predetermined volume, in the simplest possible manner. The device has a sampling tip (2) made of an incompressible and porous material, which is moved with its mouthpiece (4) in the mouth of a test subject for 1 to 2 minutes and collects saliva based on the capillary action. A reagent depot containing reagent liquid is subsequently cut up by a puncturing cylinder (9) at the sample collector, and the reagent liquid then enters the cavity (10) of the sampling tip (2). Finally, the complete pushing together of the pneumatic cylinder (26) and the cylinder tube (1) of the sample collector finally presses the saliva and the reagent liquid present in the cavity (10) through the sampling tip (2) and the filter reactor (21), which is fitted thereto in a positive-locking manner and is likewise incompressible and porous with a smaller mean pore size, so that saliva and liquid are discharged as droplets (40) in a filtered and mixed manner.
摘要翻译：提供了用于收集和释放样品液体，特别是唾液的装置以及系统和方法。该装置和系统以最简单可能的方式获得和提供限定的唾液样品，即预定体积的经过滤和均匀混合的唾液样品。该装置具有由不可压缩和多孔材料制成的采样尖端（2），其将其接口（4）移动到受检对象的口中1至2分钟，并基于毛细管作用收集唾液。随后，在试样收集器上用穿刺筒（9）将含有试剂液的试剂库进行切割，然后将试剂液体进入取样口（2）的空腔（10）。最后，将样品收集器的气缸（26）和气缸筒（1）完全推压在一起，最终通过采样尖端（2）和过滤器反应器将存在于空腔（10）中的唾液和试剂液体推压（21），其以正锁定方式安装在其上，并且具有较小平均孔径的不可压缩和多孔，使得唾液和液体以过滤和混合的方式作为液滴（40）排出。

79. 发明申请

US20040014237A1 Swab testing device and method 有权
标题翻译：拭子检测装置及方法
公开(公告)号：US20040014237A1
公开(公告)日：2004-01-22
申请号：US10390050
申请日：2003-03-17
发明人： Nobuyuki Sugiyama , Katsumi Horiuchi
IPC分类号： G01N001/00
CPC分类号： B01L3/5029 , A61B10/0096 , B01L3/50825 , B01L2300/046 , Y10T436/25
摘要： A swab testing device comprises a container (1) containing a diluent (7), a cap (10, 20) detachably mounted on an opening of the container, an elongating stick (4) secured to or integral with the cap, and a cotton swab (5) connected to a leading end of the stick and immersed in the diluent when the container opening is closed with the cap. The cap provides a communicating channel (12, 14, 27, 31) communicatable with the interior (6) of the container and also communicatable with the atmosphere by an aperture (23a) formed on the cap. The cap also includes a lid (15, 25) by which the aperture may be opened and closed. Any liquid in the container may be discharged through the communicating channel and the aperture, when the lid is opened to communicate the channel with the atmosphere through the aperture, even when the container opening remains closed with the cap.
摘要翻译：拭子检查装置包括容纳有稀释剂（7）的容器（1），可拆卸地安装在容器的开口上的盖子（10,20），固定到盖子上或与盖子一体的伸长杆（4）棉签（5）连接到棒的前端并且当容器开口用盖封闭时浸入稀释剂中。盖提供与容器的内部（6）可通信的连通通道（12,14,27,31），并且还可通过形成在盖上的孔（23a）与大气连通。盖子还包括盖子（15,25），孔可以通过该盖子打开和关闭。即使当容器开口保持关闭时，容器中的任何液体可以通过连通通道和孔排出，当打开盖子以将通道与大气通过孔连通时。

80. 发明申请

US20030197852A1 Method for analyzing impurities in carbon dioxide 有权
标题翻译：分析二氧化碳杂质的方法
公开(公告)号：US20030197852A1
公开(公告)日：2003-10-23
申请号：US10350307
申请日：2003-01-22
申请人： Praxair Technology, Inc.
发明人： Michael Clinton Johnson , Carl Joseph Heim , John Fredric Billingham , Mark Leonard Malczewski
IPC分类号： G01N001/00
CPC分类号： G01N15/06 , B01D15/40 , C01B32/50 , F25J2290/50 , G01N1/2202 , G01N1/40 , G01N1/42 , G01N15/04 , G01N33/0016 , G01N2001/2238 , G01N2001/2282 , G01N2015/0693
摘要： This invention relates to methods and systems for detecting contaminants that can precipitate and deposit on a workpiece during a carbon dioxide application, especially contaminants that are already present and dissolved in the fresh carbon dioxide fed to the application. One aspect of this invention includes a method of detecting contaminants dissolved in a carbon dioxide stream, including the steps of sampling at least a portion of the carbon dioxide stream to form a carbon dioxide sample; modifying at least one physical condition of the carbon dioxide sample to form an aerosol that includes gaseous carbon dioxide and at least one suspended contaminant; and detecting the number of particles of suspended contaminant in at least a portion of the carbon dioxide sample with at least one particle counter. A system for continuously detecting contaminants dissolved in a carbon dioxide stream is also described.
摘要翻译：本发明涉及用于检测污染物的方法和系统，所述污染物在二氧化碳施加期间可能沉淀和沉积在工件上，特别是已经存在并溶解在供应到应用中的新鲜二氧化碳中的污染物。本发明的一个方面包括检测溶解在二氧化碳流中的污染物的方法，包括对至少一部分二氧化碳流进行取样以形成二氧化碳样品的步骤; 改变二氧化碳样品的至少一种物理状态以形成包括气态二氧化碳和至少一种悬浮污染物的气溶胶; 以及用至少一个颗粒计数器检测所述二氧化碳样品的至少一部分中的悬浮污染物的颗粒数。还描述了用于连续检测溶解在二氧化碳流中的污染物的系统。

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