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71. 发明申请

US20040175433A1 Composition for the treatment of diseases which affect animals' hooves 有权
标题翻译：用于治疗影响动物蹄的疾病的组合物
公开(公告)号：US20040175433A1
公开(公告)日：2004-09-09
申请号：US10480574
申请日：2003-12-12
发明人： William Thomson
IPC分类号： A61K033/34 , A61K033/32 , A61K033/06 , A61K031/19
CPC分类号： A61K9/0017 , A61K33/30 , A61K33/34 , A61K45/06 , A61K47/02 , A61K47/36
摘要： A composition for treating a disease affecting the hoof of an animal comprising an active ingredient and a colloid former is described. The active ingredient may comprise zinc sulphate, copper sulphate, an organic acid, an alkali metal salt or a mixture thereof. The composition as disclosed has the advantage that it is more effective at applying an active ingredient to a hoof than a conventional, non-colloid system.
摘要翻译：描述了用于治疗影响动物的蹄的疾病的组合物，其包含活性成分和胶体形成剂。活性成分可以包含硫酸锌，硫酸铜，有机酸，碱金属盐或其混合物。所公开的组合物的优点在于，与常规的非胶体体系相比，将活性成分施加到蹄上更有效。

72. 发明申请

US20040170701A1 Pharmaceutical composition comprising copper, salicylic acid, vitamin c and zinc for use in treatment of different diseases such as bacterial or viral infection 审中-公开
标题翻译：包含铜，水杨酸，维生素C和锌的药物组合物，用于治疗不同疾病如细菌或病毒感染
公开(公告)号：US20040170701A1
公开(公告)日：2004-09-02
申请号：US10472190
申请日：2004-04-01
发明人： John Carter
IPC分类号： A61K033/34 , A61K033/32 , A61K033/04 , A61K033/26 , A61K031/198 , A61K031/375 , A61K031/60 , A61K031/4172
CPC分类号： A61K33/26 , A61K31/375 , A61K31/60 , A61K33/32 , A61K33/34 , A61K2300/00
摘要： Therapeutic composition comprising (a) a physiologically acceptable source of assimilable copper; (b) salicylic acid or a physiologically acceptable derivative thereof; (c) vitamin C; and (d) a physiologically acceptable source of assimilable zinc; and method for the prevention or treatment of a respiratory disease, septicemia, cellulitis, AIDS, an autoimmune disease, or a bacteria or viral infection, in particular common cold or influenza, or for enhancing the immune system.
摘要翻译：治疗组合物，其包含（a）生理上可接受的可同化铜源; （b）水杨酸或其生理上可接受的衍生物; （c）维生素C; 和（d）可吸收锌的生理学上可接受的来源; 以及用于预防或治疗呼吸系统疾病，败血症，蜂窝组织炎，艾滋病，自身免疫性疾病或细菌或病毒感染，特别是感冒或流感或用于增强免疫系统的方法。

73. 发明申请

US20040105897A1 Composition and method for the therapeutic modulation of matrix metalloproteinase 审中-公开
标题翻译：基质金属蛋白酶治疗调控的组成和方法
公开(公告)号：US20040105897A1
公开(公告)日：2004-06-03
申请号：US10645410
申请日：2003-08-21
申请人： Greystone Medical Group, Inc.
发明人： Stephen H. Monroe , Hans Hoekstra
IPC分类号： A61K033/32 , A61K033/00
CPC分类号： A61K31/075 , A61K31/19 , A61K33/00 , A61K33/06 , A61K33/24 , A61K33/30 , A61K45/06 , A61L15/18 , A61L15/44 , A61L2300/102 , A61L2300/412 , A61K2300/00
摘要： A synthesized composition containing one or more of zinc ions, calcium ions, rubidium ions and/or potassium ions in a pharmaceutically acceptable carrier, which, when administered to a patient in need thereof, effectively modulates the activity of at least MMP-2 and/or MMP-9 in the wound. A method is disclosed.
摘要翻译：在药学上可接受的载体中含有锌离子，钙离子，铷离子和/或钾离子中的一种或多种的合成组合物，其在施用于有需要的患者时有效调节至少MMP-2和/ 或MMP-9。公开了一种方法。

74. 发明申请

US20040096520A1 Manganese compositions for reducing/preventing skin wrinkles and fine lines 审中-公开
标题翻译：用于减少/预防皮肤皱纹和细纹的锰组合物
公开(公告)号：US20040096520A1
公开(公告)日：2004-05-20
申请号：US10702736
申请日：2003-11-07
申请人： SOCIETE L'OREAL S.A.
发明人： Isabelle Nonotte , Lionel Breton
IPC分类号： A61K033/32 , A61K031/28
CPC分类号： A61K8/97 , A61K8/19 , A61K8/365 , A61Q19/00 , A61Q19/08
摘要： A regime/regimen for relaxing and/or slackening human cutaneous and/or subcutaneous tissue, in particular for treating wrinkles and fine lines in the skin, comprising administering to an individual subject in need of such treatment, a thus-effective amount of manganese and/or at least one organic and/or inorganic salt thereof.
摘要翻译：用于松弛和/或松弛人皮肤和/或皮下组织的方案/方案，特别是用于治疗皮肤中的皱纹和细纹，包括对需要这种治疗的个体受试者施用如此有效量的锰和 /或其至少一种有机和/或无机盐。

75. 发明申请

US20040037910A1 Compositions of oak bark extract, related syntheic compositions and method of using same 审中-公开
标题翻译：橡树皮提取物组合物，相关合成组合物及其使用方法
公开(公告)号：US20040037910A1
公开(公告)日：2004-02-26
申请号：US10645411
申请日：2003-08-21
发明人： David N. S. Hon , R. Thomas Stanley
IPC分类号： A61K035/78 , A61K033/32 , A61K033/06 , A61K033/00
CPC分类号： A61K36/49 , A61K33/00 , A61K33/24 , A61K2300/00
摘要： Higher concentrations of oak bark ash extract, i.e., greater than 20% by weight, are useful for the treatment of skin cancers. Lower concentrations of oak bark extract possess additional therapeutic properties not heretofore recognized. For example, preparations containing 40-80% oak bark extract are useful in the treatment of acute cancerous skin ulcers. In addition, synthetic mixtures containing potassium ions, zinc ions, calcium ions provide many of the same advantageous properties of oak bark extract. The inclusion of rubidium ions and sulfur is also advantageous for some applications.
摘要翻译：较高浓度的橡皮树皮提取物，即大于20重量％，可用于治疗皮肤癌。较低浓度的橡皮树皮提取物具有迄今未被认可的额外治疗特性。例如，含有40-80％橡树皮提取物的制剂可用于治疗急性癌性皮肤溃疡。此外，含有钾离子，锌离子，钙离子的合成混合物提供了许多与橡皮树皮提取物相同的有利特性。包含铷离子和硫在一些应用中也是有利的。

76. 发明申请

US20040033270A1 Nano-sized zinc oxide in hygiene products 审中-公开
标题翻译：纳米级氧化锌在卫生用品中
公开(公告)号：US20040033270A1
公开(公告)日：2004-02-19
申请号：US10462976
申请日：2003-06-17
发明人： Christian Kropf , Claudia Hundeiker , Melita Heller , Christine Wild
IPC分类号： A61K033/32 , A61F013/15 , A61F013/20
CPC分类号： C09C1/043 , A61L15/18 , A61L15/46 , A61L2300/102 , A61L2300/404 , A61L2300/624 , B82Y30/00 , C01P2004/64
摘要： Hygiene products such as diapers, tampons, pantyliners and the like are produced using zinc oxide in the form of nanoparticles having surfaces that have been chemically and/or physically modified. The surface modification may be carried out using organic compounds such as carboxylic acids, carboxylic acid derivatives, amino acids, hydroxycarboxylic acids, sugar acids, polyglycolic acids, ether carboxylic acids, alkyl halides, or silanes.
摘要翻译：使用具有化学和/或物理修饰表面的纳米颗粒形式的氧化锌制备诸如尿布，卫生棉条，内裤等的卫生产品。表面改性可以使用有机化合物如羧酸，羧酸衍生物，氨基酸，羟基羧酸，糖酸，聚乙醇酸，醚羧酸，烷基卤化物或硅烷进行。

77. 发明申请

US20030228375A1 Composition and method for increasing testosterone levels 审中-公开
公开(公告)号：US20030228375A1
公开(公告)日：2003-12-11
申请号：US10133767
申请日：2002-04-25
申请人： A. Glenn Braswell
发明人： Inna Yegorova
IPC分类号： A61K035/78 , A61K033/32 , A61K031/57 , A61K031/19 , A61K031/015
CPC分类号： A61K31/57 , A61K31/015 , A61K31/19 , A61K33/30 , A61K35/36 , A61K36/00 , A61K36/185 , A61K36/33 , A61K36/42 , A61K36/48 , A61K36/889 , A61K2300/00
摘要： This invention provides compositions and methods related to the administration of deer antler, one or more nor-testosterone precursors, and one or more testosterone precursors, to increase testosterone levels, treat sexual dysfunction, improve sexual function, improve energy, enhance feelings of well-being and increase muscle mass in males. This invention also provides for inhibitors of the enzymes aromatase and/or 5-alpha reductase, to support testosterone levels and avoid undesirable metabolites.

78. 发明申请

US20030215430A1 Composition for the treatment and prevention of endothelial dysfunction 失效
标题翻译：用于治疗和预防内皮功能障碍的组合物
公开(公告)号：US20030215430A1
公开(公告)日：2003-11-20
申请号：US10436528
申请日：2003-05-14
发明人： Edward J. Petrus
IPC分类号： A61K031/714 , A61K031/7008 , A61K038/43 , A61K031/59 , A61K031/525 , A61K031/355 , A61K035/78 , A61K033/06 , A61K033/32
CPC分类号： A61K9/0056 , A61K31/525 , A61K31/60 , A61K31/70
摘要： This invention relates to a method and compositions for the treatment and prevention of disorders associated with endothelial dysfunction consisting of anti-inflammatory agents and dietary supplements.
摘要翻译：本发明涉及用于治疗和预防由抗炎剂和膳食补充剂组成的与内皮功能障碍相关的疾病的方法和组合物。

79. 发明申请

US20030180380A1 Treatment of colds, flu like infections and other general nasal based infections with a solution containing iodine and other broad spectrum microbicides and a method for its use 有权
标题翻译：用含有碘和其他广谱杀微生物剂的溶液治疗感冒，感染感染和其他一般鼻腔感染及其使用方法
公开(公告)号：US20030180380A1
公开(公告)日：2003-09-25
申请号：US10139531
申请日：2002-05-06
发明人： Richard L. Hansen
IPC分类号： A61K033/32 , A61L009/04 , A61K009/14 , A61K033/14 , A61K033/36
CPC分类号： A61K33/18 , A61K9/0043 , A61K33/06 , A61K33/14 , A61K33/20 , A61K33/30 , Y02A50/402 , Y10S514/849 , A61K2300/00
摘要： The invention relates generally to a method which utilizes iodine as a broad spectrum microbicide wherein the active agent may be applied in nasal passages in the manner of a decongestant type nose spray. The spray is intended particularly for human use. It is to be applied in the event of known or suspected exposure of the individual to common cold virus, flu, or other infective microbial agents including for example, bacteria, viruses, rickettsia, and even mold and fungus. The active agent is based on an iodine solution and may also contain one or more of the following: sodium hypochlorite solution, or a solution of chlorine or hypochlorites plus a salt of chloride, bromide or iodide. Alternatively, the solution may further contain iodine and a bromine solution, or a solution of iodine, bromine plus a salt of chloride, bromide or iodide such as sodium chloride, zinc chloride, sodium bromide, zinc bromide, sodium iodide or zinc iodide. The iodine, chlorine, hypochlorites, bromine, chloride, bromide, and iodide may originally come from inorganic compounds or organic compounds, which are then dissolved in the water. Further, the solution may contain glycerin or another moisturizing or wetting agent for the nasal mucosa since the halogens or halides may be dehydrating or drying. Zinc gluconate or a zinc halide such as zinc chloride, zinc bromide or zinc iodide may also be included to further render the nasal mucosa more slippery and thus render it more difficult for invading microbes to colonize the area.
摘要翻译：本发明一般涉及利用碘作为广谱杀微生物剂的方法，其中活性剂可以以减充血剂型鼻喷雾的方式施用于鼻道。喷雾特别适合人类使用。如果个体已知或疑似暴露于普通感冒病毒，流感或其他感染性微生物试剂（包括细菌，病毒，立克次体，甚至霉菌和真菌），则适用。活性剂基于碘溶液，并且还可以含有以下一种或多种：次氯酸钠溶液，或氯或次氯酸盐加上氯化物，溴化物或碘化物的盐的溶液。或者，该溶液还可以含有碘和溴溶液，或碘，溴加氯化物，溴化物或碘化物的盐如氯化钠，氯化锌，溴化钠，溴化锌，碘化钠或碘化锌的溶液。碘，氯，次氯酸盐，溴，氯化物，溴化物和碘化物可能最初来自无机化合物或有机化合物，然后溶解在水中。此外，溶液可以含有甘油或其他用于鼻粘膜的保湿剂或润湿剂，因为卤素或卤化物可以是脱水或干燥的。还可以包括葡萄糖酸锌或卤化锌，如氯化锌，溴化锌或碘化锌，以进一步使鼻粘膜更加滑爽，从而使微生物侵入该区域变得更加困难。

80. 发明申请

US20030157190A1 Method of increasing fertility and athletic performance in horses 审中-公开
标题翻译：增加马的生育力和运动表现的方法
公开(公告)号：US20030157190A1
公开(公告)日：2003-08-21
申请号：US10348344
申请日：2003-01-22
发明人： Gordon L. Woods
IPC分类号： A61K033/32
CPC分类号： A61K33/30
摘要： Compositions comprising a biologically available and physiologically acceptable zinc salt are administered to horses to increase their fertility and reproduction. These compositions also can be administered to increase horses' athletic performance.
摘要翻译：将包含生物可获得的和生理上可接受的锌盐的组合物施用于马以增加其生育力和繁殖力。这些组合物也可以施用以增加马的运动表现。

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