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71. 发明授权

EP0034012B1 2-nitro-5-(substituted-phenoxy) phenylalkanone oxime and imine derivatives as herbicides 有权转让
标题翻译： 2-硝基-5-（取代 - 苯氧基）苯基酮氧化物和作为除草剂的烟酰胺衍生物
公开(公告)号：EP0034012B1
公开(公告)日：1984-09-12
申请号：EP81300350.6
申请日：1981-01-27
申请人： RHONE-POULENC AGROCHIMIE
发明人： Theissen, Robert James
IPC分类号： C07C119/06 , C07C131/00 , A01N35/10
CPC分类号： C07D303/12 , A01N35/10 , A01N37/36 , A01N37/50 , A01N37/52 , A01N43/20 , A01N47/24

72. 发明授权

US11976053B2 Process of preparing a peptide epoxyketone immunoproteasome inhibitor, and precursors thereof 有权
公开(公告)号：US11976053B2
公开(公告)日：2024-05-07
申请号：US17965064
申请日：2022-10-13
申请人： KEZAR LIFE SCIENCES
发明人： Henry Johnson , Sean Dalziel , Dustin McMinn
IPC分类号： C07D295/13 , C07C229/36 , C07D295/15 , C07D301/02 , C07D303/12 , C07D303/32 , C07D303/46
CPC分类号： C07D295/13 , C07C229/36 , C07D295/15 , C07D301/02 , C07D303/12 , C07D303/32 , C07D303/46 , C07B2200/13
摘要： Disclosed herein are methods for preparing [(2S,3R)—N—[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamide (compound “G”):

and precursors thereof.

73. 发明授权

US11702578B2 Thermally conductive material, device with thermally conductive layer, composition for forming thermally conductive material, and disk-like liquid crystal compound 有权
公开(公告)号：US11702578B2
公开(公告)日：2023-07-18
申请号：US16741286
申请日：2020-01-13
申请人： FUJIFILM Corporation
发明人： Seiichi Hitomi , Keita Takahashi , Teruki Niori , Yuji Yoshida
IPC分类号： C09K5/14 , C07C43/23 , C07C69/88 , C07C223/06 , C07C261/02 , C07C321/26 , C07C323/52 , C07D271/10 , C07D303/12 , C07D307/89 , C08G59/24 , C08G59/40 , C08G59/42 , C08G59/50 , C08G59/62 , C08G65/40 , C08J5/18 , C08K3/38 , H01L23/373
CPC分类号： C09K5/14 , C07C43/23 , C07C69/88 , C07C223/06 , C07C261/02 , C07C321/26 , C07C323/52 , C07D271/10 , C07D303/12 , C07D307/89 , C08G59/245 , C08G59/4014 , C08G59/423 , C08G59/4238 , C08G59/504 , C08G59/5046 , C08G59/621 , C08G65/40 , C08J5/18 , C08K3/38 , C08J2363/00 , C08J2371/10 , C08K2003/385 , C08K2201/001 , H01L23/3737
摘要： The present invention provides a thermally conductive material having excellent thermal conductivity. Furthermore, the present invention provides a device with a thermally conductive layer that has a thermally conductive layer containing the thermally conductive material and a composition for forming a thermally conductive material that is used for forming the thermally conductive material. The thermally conductive material according to an embodiment of the present invention contains a cured substance of a disk-like compound, which has one or more reactive functional groups selected from the group consisting of a hydroxyl group, a carboxylic acid group, a carboxylic acid anhydride group, an amino group, a cyanate ester group, and a thiol group, and a crosslinking compound which has a group reacting with the reactive functional groups.

74. 发明授权

US09896535B2 Epoxy compound having alkoxysilyl group, method of preparing the same, composition and cured product comprising the same, and uses thereof 有权
公开(公告)号：US09896535B2
公开(公告)日：2018-02-20
申请号：US14805339
申请日：2015-07-21
申请人： KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY
发明人： Hyun-Aee Chun , Sang-Yong Tak , Su-Jin Park , Yun-Ju Kim , Sung-Hwan Park
IPC分类号： C08L63/00 , C08G59/02 , C08G59/30 , C08K7/14 , C07F7/18 , C07D407/12 , C07D303/12 , C08J5/24 , C08K3/36
CPC分类号： C08G59/306 , C07D303/12 , C07D407/12 , C07F7/1804 , C07F7/1876 , C08J5/24 , C08J2363/00 , C08K3/36 , C08K7/14 , C08L63/00
摘要： Disclosed are an epoxy compound having an alkoxysilyl group, a composite of which exhibits good heat resistant properties and/or a cured product of which exhibits good flame retardant properties, a method of preparing the same, a composition comprising the same, and a cured product and a use of the composition. An alkoxysilylated epoxy compound comprising at least one of Chemical Formula S1 substituent and at least two epoxy groups in a core, a method of preparing the epoxy compound by an allylation, a claisen rearrangement, an epoxidation and an alkoxysilylation, an epoxy composition comprising the epoxy compound, and a cured product and a use of the composition are provided. The composite of the disclosed exhibits improved chemical bonding, good heat resistant properties, a low CTE, a high glass transition temperature or Tg-less. The cured product of the composition exhibits good flame retardant properties.

75. 发明申请

US20150119463A1 14-HYDROXY-DOCOSAHEXAENOIC ACID COMPOUNDS 有权
公开(公告)号：US20150119463A1
公开(公告)日：2015-04-30
申请号：US14557151
申请日：2014-12-01
申请人： The Brigham and Women's Hospital, Inc.
发明人： Charles N. SERHAN , Rong YANG
IPC分类号： A61K31/202 , A61Q5/00 , A61K8/365 , A61Q19/08
CPC分类号： C07D303/38 , A23K20/158 , A61K8/365 , A61K8/37 , A61K8/4973 , A61K31/202 , A61Q5/006 , A61Q19/00 , A61Q19/08 , C07C59/42 , C07C59/58 , C07C69/732 , C07D303/12 , Y02P20/55
摘要： The invention describes novel 14-hydroxy docosahexaenoic acid (DHA) analogues, their preparation, isolation, identification, purification and uses thereof.

76. 发明申请

US20150119460A1 14-HYDROXY-DOCOSAHEXAENOIC ACID COMPOUNDS 有权
标题翻译： 14-羟基 - 二氧六环酸化合物
公开(公告)号：US20150119460A1
公开(公告)日：2015-04-30
申请号：US14557230
申请日：2014-12-01
申请人： The Brigham and Women's Hospital, Inc.
发明人： Charles N. SERHAN , Rong YANG
IPC分类号： C07D303/38 , A61K8/365 , A61K8/49 , C07C59/42 , A61Q19/08 , A61Q5/00
CPC分类号： C07D303/38 , A23K20/158 , A61K8/365 , A61K8/37 , A61K8/4973 , A61K31/202 , A61Q5/006 , A61Q19/00 , A61Q19/08 , C07C59/42 , C07C59/58 , C07C69/732 , C07D303/12 , Y02P20/55
摘要： The invention describes novel 14-hydroxy docosahexaenoic acid (DHA) analogues, their preparation, isolation, identification, purification and uses thereof.
摘要翻译：本发明描述了新型的14-羟基二十二碳六烯酸（DHA）类似物，其制备，分离，鉴定，纯化和用途。

77. 发明申请

US20150005513A1 PROCESS FOR THE PRODUCTION OF ACID ANHYDRIDES FROM EPOXIDES 有权
标题翻译：从环氧化物生产酸酐的方法
公开(公告)号：US20150005513A1
公开(公告)日：2015-01-01
申请号：US14378290
申请日：2013-02-12
申请人： Novomer, Inc.
发明人： Han Lee , Michael A. Slowik
IPC分类号： C07D307/60 , B01J31/22 , C07D305/12
CPC分类号： C07D307/60 , B01J31/2295 , B01J2231/48 , B01J2531/31 , B01J2531/845 , C07D303/12 , C07D305/12
摘要： A method of making acid anhydrides from epoxide and carbon monoxide feedstocks is presented. In various aspects, the method includes steps of reacting the contents of a feed stream comprising an epoxide, a solvent, a carbonylation catalyst and carbon monoxide to produce a first carbonylation product stream comprising a beta-lactone, then reacting the contents of the first carbonylation product stream with additional carbon monoxide to produce a second carbonylation product stream comprising an acid anhydride, and separating at least a portion of the acid anhydride from the second carbonylation product stream to produce: i) an acid anhydride product stream comprising the separated portion of acid anhydride; and ii) a recycling stream comprising the carbonylation catalyst, and finally adding the recycling stream to the feed stream.
摘要翻译：提出了从环氧化物和一氧化碳原料制备酸酐的方法。在各个方面，该方法包括使包含环氧化物，溶剂，羰基化催化剂和一氧化碳的进料流的内容物反应以产生包含β-内酯的第一羰基化产物流，然后使第一羰基化反应的内容物产生含有一氧化碳的产物流以产生包含酸酐的第二羰基化产物流，并将至少一部分酸酐与第二羰基化产物流分离以产生：i）包含酸的分离部分的酸酐产物流酐; 和ii）包含羰基化催化剂的再循环流，最后将再循环流加入进料流中。

78. 发明申请

US20140336251A1 METHODS OF TREATING AGE RELATED DISORDERS 有权
标题翻译：治疗老年相关疾病的方法
公开(公告)号：US20140336251A1
公开(公告)日：2014-11-13
申请号：US14244278
申请日：2014-04-03
申请人： Zafgen, Inc.
发明人： Thomas E. Hughes , James E. Vath
IPC分类号： A61K31/336 , C07D303/18
CPC分类号： A61K31/336 , A61K9/0019 , A61K9/0053 , A61K31/335 , A61K31/7088 , A61K31/713 , C07D303/08 , C07D303/12 , C07D303/18
摘要： The invention generally relates to methods of treating a patient having, and/or at risk of, oxidative distress disorders and/or age-related disorders. The disclosure also generally relates to methods of treating memory impairment or enhancing the cognitive function of a patient in need thereof. Such methods may include administering a therapeutically effective amount of a MetAP2 inhibitor.
摘要翻译：本发明一般涉及治疗患有氧化性窘迫障碍和/或年龄相关疾病和/或处于危险中的患者的方法。本公开还通常涉及治疗记忆障碍或增强有此需要的患者的认知功能的方法。这样的方法可以包括施用治疗有效量的MetAP2抑制剂。

79. 发明申请

US20140179836A1 EPOXY COMPOUND HAVING ALKOXYSILYL GROUP, METHOD OF PREPARING THE SAME, COMPOSITION AND CURED PRODUCT COMPRISING THE SAME, AND USES THEREOF 有权
标题翻译：具有烷氧基的环氧化合物，其制备方法，包含其的组合物和固化产物及其用途
公开(公告)号：US20140179836A1
公开(公告)日：2014-06-26
申请号：US14190043
申请日：2014-02-25
申请人： KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY
发明人： Hyun-Aee CHUN , Sang-Yong TAK , Su-Jin PARK , Yun-Ju KIM , Sung-Hwan PARK
IPC分类号： C07F7/08 , C08K7/14 , C08G59/30
CPC分类号： C08G59/306 , C07D303/12 , C07D407/12 , C07F7/1804 , C07F7/1876 , C08J5/24 , C08J2363/00 , C08K3/36 , C08K7/14 , C08L63/00
摘要： Disclosed are an epoxy compound having an alkoxysilyl group, a composite of which exhibits good heat resistant properties and/or a cured product of which exhibits good flame retardant properties, a method of preparing the same, a composition comprising the same, and a cured product and a use of the composition. An alkoxysilylated epoxy compound comprising at least one of Chemical Formula S1 substituent and at least two epoxy groups in a core, a method of preparing the epoxy compound by an allylation, a claisen rearrangement, an epoxidation and an alkoxysilylation, an epoxy composition comprising the epoxy compound, and a cured product and a use of the composition are provided. The composite of the disclosed exhibits improved chemical bonding, good heat resistant properties, a low CTE, a high glass transition temperature or Tg-less The cured product of the composition exhibits good flame retardant properties.
摘要翻译：公开了具有烷氧基甲硅烷基的环氧化合物，其具有良好的耐热性的复合材料和/或其具有良好阻燃性能的固化产物，其制备方法，包含该组合物的组合物和固化产物和使用该组合物。烷氧基硅烷基化环氧化合物，其包含核心中的化学式S1取代基和至少两个环氧基中的至少一个，通过烯丙基化制备环氧化合物的方法，克莱森重排，环氧化和烷氧基硅烷基化，包含环氧树脂化合物，以及固化产物和组合物的用途。所公开的复合材料显示出改善的化学键合，良好的耐热性能，低CTE，高玻璃化转变温度或Tg。组合物的固化产物显示出良好的阻燃性能。

80. 发明授权

US08399692B2 Epichlorohydrin, manufacturing process and use 有权
标题翻译：表氯醇，制造工艺及用途
公开(公告)号：US08399692B2
公开(公告)日：2013-03-19
申请号：US12663749
申请日：2008-06-11
申请人： Philippe Krafft , Patrick Gilbeau , Dominique Balthasart , Noel Boulos
发明人： Philippe Krafft , Patrick Gilbeau , Dominique Balthasart , Noel Boulos
IPC分类号： C07D301/12
CPC分类号： C07D303/12 , C07D301/27 , C07D301/28 , C07F9/65502 , C08G59/00 , C08G59/02
摘要： Product containing epichlorohydrin, wherein the amount of trichloropropane is of less than 0.01 g of trichloropropane per kg of product, a process for manufacturing the product and its use in various applications.
摘要翻译：含有表氯醇的产品，其中三氯丙烷的量小于每千克产品0.01克三氯丙烷，制造该产品的方法及其在各种应用中的应用。

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