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71. 发明授权

US07850930B2 Microreactor 失效
标题翻译：微反应器
公开(公告)号：US07850930B2
公开(公告)日：2010-12-14
申请号：US11835439
申请日：2007-08-08
申请人： Tetsuo Miyamoto , Hajime Kato , Shigenori Togashi
发明人： Tetsuo Miyamoto , Hajime Kato , Shigenori Togashi
IPC分类号： B01J19/00
CPC分类号： B01F13/0062 , B01F5/0646 , B01F5/0651 , B01F5/0653 , B01F13/0066 , B01F13/1013 , B01F13/1022 , B01J19/0093 , B01J2219/00783 , B01J2219/00889
摘要： The microreactor for mixing and discharging multiple raw material liquids is obtained by laminating: a base plate in which a raw material introducing fluid channel is formed; a raw material introducing plate; and a mixing fluid channel plate which is arranged between the base plate and the raw material introducing plate, and in which a mixing fluid channel is formed. The microreactor includes: a mixing fluid channel in the mixing fluid channel plate which is formed in the mixing fluid channel plate, and in which a flow is contracted in its width direction; and a mixing fluid channel in the base plate which is formed in the base plate, and which has a fluid channel cross-section which becomes larger in its depth direction as it goes downstream. The mixing fluid channel in the base plate communicates with the mixing fluid channel in the mixing fluid channel plate, and is connected to an outlet orifice from which to discharge the mixed liquids.
摘要翻译：用于混合和排出多种原料液体的微反应器通过层压：其中形成有原料引入流体通道的基板; 原材料导入板; 以及设置在基板和原料导入板之间的混合流体通道板，其中形成混合流体通道。微反应器包括：混合流体通道板中的混合流体通道，其形成在混合流体通道板中，并且流体在其宽度方向上收缩; 以及形成在基板中的底板中的混合流体通道，并且具有在其下游沿其深度方向变大的流体通道横截面。基板中的混合流体通道与混合流体通道板中的混合流体通道连通，并连接到排出混合液体的出口孔。

72. 发明申请

US20080197516A1 Micro-Bubble Generator, Vortex Breakdown Nozzle for Micro-Bubble Generator, Vane Swirler for Micro-Bubble Generator, Micro-Bubble Generating Method, and Micro-Bubble Applying Device 失效
标题翻译：微气泡发生器，微气泡发生器的涡流分解喷嘴，微气泡发生器的叶片旋流器，微气泡发生方法和微泡应用装置
公开(公告)号：US20080197516A1
公开(公告)日：2008-08-21
申请号：US11813793
申请日：2005-11-11
申请人： Harumichi Abe , Kazuo Matsuuchi , Minoru Iidaka
发明人： Harumichi Abe , Kazuo Matsuuchi , Minoru Iidaka
IPC分类号： B01F3/04
CPC分类号： C02F1/006 , A01K63/042 , B01F3/0446 , B01F5/0646 , B01F5/0651 , B01F5/0665 , B01F5/0671 , B01F2003/04858 , B01F2003/04865 , B01F2003/04872 , B01F2003/04879 , B01F2003/04886 , B01F2003/04914 , B01F2005/0017 , B01F2215/0052 , C02F1/72 , C02F1/78 , C02F2301/024 , C02F2301/026
摘要： There is provided a micro-bubble generator including a swirling-flow generating vane nozzle and vortex breakdown nozzle connected coaxially to each other. The swirling flow generating vane nozzle produces a swirling flow of a liquid having a gas introduced to the center thereof from a gas feeding unit. The swirling flow is supplied to a flow constricting section included in the vortex breakdown nozzle to provide micro bubbles from a vortex breakdown section also included in the vortex breakdown nozzle.
摘要翻译：提供了包括旋流产生叶片喷嘴和彼此同轴连接的涡流破坏喷嘴的微气泡发生器。旋流产生叶片喷嘴产生具有从气体供给单元引入其中心的气体的液体的旋转流。涡旋流被提供到包括在涡流破坏喷嘴中的流动收缩部分，以提供也包括在涡流破坏喷嘴中的涡流击穿部分的微气泡。

73. 发明申请

US20080085227A1 MICROREACTOR 失效
公开(公告)号：US20080085227A1
公开(公告)日：2008-04-10
申请号：US11835439
申请日：2007-08-08
申请人： Tetsuo Miyamoto , Hajime Kato , Shigenori Togashi
发明人： Tetsuo Miyamoto , Hajime Kato , Shigenori Togashi
IPC分类号： B01J19/00
CPC分类号： B01F13/0062 , B01F5/0646 , B01F5/0651 , B01F5/0653 , B01F13/0066 , B01F13/1013 , B01F13/1022 , B01J19/0093 , B01J2219/00783 , B01J2219/00889
摘要： The microreactor for mixing and discharging multiple raw material liquids is obtained by laminating: a base plate in which a raw material introducing fluid channel is formed; a raw material introducing plate; and a mixing fluid channel plate which is arranged between the base plate and the raw material introducing plate, and in which a mixing fluid channel is formed. The microreactor includes: a mixing fluid channel in the mixing fluid channel plate which is formed in the mixing fluid channel plate, and in which a flow is contracted in its width direction; and a mixing fluid channel in the base plate which is formed in the base plate, and which has a fluid channel cross-section which becomes larger in its depth direction as it goes downstream. The mixing fluid channel in the base plate communicates with the mixing fluid channel in the mixing fluid channel plate, and is connected to an outlet orifice from which to discharge the mixed liquids.
摘要翻译：用于混合和排出多种原料液体的微反应器通过层压：其中形成有原料引入流体通道的基板; 原材料导入板; 以及设置在基板和原料导入板之间的混合流体通道板，其中形成混合流体通道。微反应器包括：混合流体通道板中的混合流体通道，其形成在混合流体通道板中，并且流体在其宽度方向上收缩; 以及形成在基板中的底板中的混合流体通道，并且具有在其下游沿其深度方向变大的流体通道横截面。基板中的混合流体通道与混合流体通道板中的混合流体通道连通，并连接到排出混合液体的出口孔。

74. 发明申请

US20080003284A1 LEVOTHYROXINE COMPOSITIONS AND METHOS 审中-公开
标题翻译：左氧氟沙星组合物和甲醇
公开(公告)号：US20080003284A1
公开(公告)日：2008-01-03
申请号：US11855852
申请日：2007-09-14
申请人： G. Franz , Elaine Strauss , Phillip DiMenna , Rocco Gemma
发明人： G. Franz , Elaine Strauss , Phillip DiMenna , Rocco Gemma
IPC分类号： A61K31/197 , A61K9/20 , A61P5/14
CPC分类号： A61K9/0031 , A61K9/02 , A61K9/2054 , A61K9/2072 , A61K31/195 , A61K31/197 , A61K31/198 , B01F3/18 , B01F5/0646 , B01F5/0651 , B01F5/241
摘要： The present invention generally relates to stable pharmaceutical compositions, and methods of making and administering such compositions. In one aspect, the invention features stabilized pharmaceutical compositions that include pharmaceutically active ingredients such as levothyroxine (T4) sodium and liothyronine (T3) sodium (thyroid hormone drugs), preferably in an immediate release solid dosage form. Also provided are methods for making and using such immediate release and stabilized compositions.
摘要翻译：本发明一般涉及稳定的药物组合物，以及制备和施用这些组合物的方法。一方面，本发明的特征在于稳定的药物组合物，其包括药物活性成分，例如左甲状腺素（T4）钠和氨基丝氨酸（T3）钠（甲状腺激素药物），优选为立即释放固体剂型。还提供了制备和使用这种立即释放和稳定的组合物的方法。

75. 发明申请

US20070211570A1 Static mixing element and method of mixing a drilling liquid 有权
标题翻译：静态混合元件和混合钻井液的方法
公开(公告)号：US20070211570A1
公开(公告)日：2007-09-13
申请号：US11748313
申请日：2007-05-14
申请人： Manfred Schauerte
发明人： Manfred Schauerte
IPC分类号： B01F5/06
CPC分类号： B01F5/0682 , B01F5/0646 , B01F5/0651 , B01F5/0688 , B01F13/1013 , B01F2013/1052
摘要： Static mixer element for homogenizing media and methods of mixing a drilling liquid are disclosed. The static mixer includes a housing and a deflection surface arranged within the housing at a selected angle with respect to the flow direction.
摘要翻译：公开了用于均质化介质的静态混合器元件和混合钻井液的方法。静态混合器包括壳体和偏转表面，其相对于流动方向以选定的角度布置在壳体内。

76. 发明申请

US20040246814A1 Method for mixing a liquid/liquid and/or gaseous media into a solution 失效
标题翻译：将液体/液体和/或气体介质混合到溶液中的方法
公开(公告)号：US20040246814A1
公开(公告)日：2004-12-09
申请号：US10478944
申请日：2004-08-02
发明人： Weng Chuen Foong , Paul Woodley
IPC分类号： B01F005/06
CPC分类号： B01F5/0646 , B01F3/0446 , B01F3/08 , B01F5/0057 , B01F5/0644 , B01F5/0651 , B01F13/1025
摘要： The invention relates to a mechanical device with no moving parts that homogeneously mixes two or more liquids or liquids and gases. It is possible with the device to totally saturate liquids with gas droplets of less than one micron. The device comprises an inlet for partially mixed components leading to a plurality of passageways converging axially into a chamber which has radial openings into another chamber defined by a conical member converging in the axial direction and having an opening at its apex to exit the mixed components, the components exiting the radial openings collide with the walls of the conical member producing shear and turbulence and subsequently spinning within the conical member and are then subjected to increased pressure in the axial direction by the converging wall of the conical member.
摘要翻译：本发明涉及一种没有均匀混合两种或多种液体或液体和气体的移动部件的机械装置。使用小于1微米的气滴可以使设备完全饱和液体。该装置包括用于部分混合部件的入口，其通过轴向会聚的多个通道，所述多个通道具有径向开口，该腔室具有径向开口，该腔室由沿轴向方向会聚的锥形部件限定，并且在其顶点具有开口以离开混合部件，离开径向开口的部件与锥形部件的壁碰撞产生剪切和湍流，随后在锥形部件内旋转，然后通过锥形部件的会聚壁在轴向上受到增加的压力。

77. 发明申请

US20040037161A1 Emulsifying method and apparatus 审中-公开
标题翻译：乳化方法和装置
公开(公告)号：US20040037161A1
公开(公告)日：2004-02-26
申请号：US10644517
申请日：2003-08-19
申请人： Yamatake Corporation
发明人： Nobuaki Honda , Kazuhiro Mae
IPC分类号： B01F005/06
CPC分类号： B01F13/0066 , B01F3/0807 , B01F5/061 , B01F5/0615 , B01F5/0646 , B01F5/0651 , B01F2005/0621 , B01F2215/0431 , B01F2215/044 , B01F2215/045
摘要： An emulsifying apparatus includes a multistage channel provided between plural inlets and a single outlet and having plural channel stages. A sectional area of the individual channel stage is larger than that of the immediately downstream channel stage on the outlet side, so that shearing rate of fluids flowing in the multistage channel gradually increases toward the outlet side to promote fluid dispersion, whereby a high-quality emulsion having an uniform particle diameter is produced with excellent mass producibility.
摘要翻译：乳化装置包括设置在多个入口和单个出口之间并具有多个通道级的多级通道。单个通道级的截面面积大于出口侧的直接下游通道级的截面积，使得在多级通道中流动的流体的剪切速率朝着出口侧逐渐增加以促进流体分散，由此高质量制造具有均匀粒径的乳液，具有优异的批量生产能力。

78. 发明申请

US20030224047A1 Levothyroxine compositions and methods 审中-公开
公开(公告)号：US20030224047A1
公开(公告)日：2003-12-04
申请号：US10425007
申请日：2003-04-28
发明人： G. Andrew Franz , Elaine A. Strauss , Philip A. DiMenna , Rocco L. Gemma
IPC分类号： A61K031/198 , A61K009/22
CPC分类号： A61K9/0031 , A61K9/02 , A61K9/2054 , A61K9/2072 , A61K31/195 , A61K31/197 , A61K31/198 , B01F3/18 , B01F5/0646 , B01F5/0651 , B01F5/241
摘要： The present invention generally relates to stable pharmaceutical compositions, and methods of making and administering such compositions. In one aspect, the invention features stabilized pharmaceutical compositions that include pharmaceutically active ingredients such as levothyroxine (T4) sodium and liothyronine (T3) sodium (thyroid hormone drugs), preferably in an immediate release solid dosage form. Also provided are methods for making and using such immediate release and stabilized compositions.

79. 发明专利

JP4677969B2 Microreactor 有权
公开(公告)号：JP4677969B2
公开(公告)日：2011-04-27
申请号：JP2006274578
申请日：2006-10-06
申请人：株式会社日立プラントテクノロジー
发明人：宗加藤 , 哲郎宮本 , 盛典富樫
IPC分类号： B01J19/00 , B01F5/00 , G01N37/00
CPC分类号： B01F13/0062 , B01F5/0646 , B01F5/0651 , B01F5/0653 , B01F13/0066 , B01F13/1013 , B01F13/1022 , B01J19/0093 , B01J2219/00783 , B01J2219/00889

80. 发明专利

JP4174576B2 A fluid composed of two or more liquid or liquid and gas are mixed, the mixing apparatus to a solution 有权
公开(公告)号：JP4174576B2
公开(公告)日：2008-11-05
申请号：JP2002593047
申请日：2002-05-22
申请人：ワールドマックスアライアンスリミテッド
发明人：ウッドレイ、ポール , チェンフーン、ウェン
IPC分类号： B01F3/04 , B01F3/08 , B01F5/00 , B01F5/06 , B01F13/10
CPC分类号： B01F5/0646 , B01F3/0446 , B01F3/08 , B01F5/0057 , B01F5/0644 , B01F5/0651 , B01F13/1025

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