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    • 78. 发明申请
    • ELECTRICALLY DRIVEN DEVICES FOR SURFACE ENHANCED RAMAN SPECTROSCOPY
    • 用于表面增强拉曼光谱的电驱动装置
    • US20120113420A1
    • 2012-05-10
    • US13384456
    • 2009-09-17
    • Huei Pei KuoShih-Yuan WangMin HuZhiyong LiAlexander M. Bratkovski
    • Huei Pei KuoShih-Yuan WangMin HuZhiyong LiAlexander M. Bratkovski
    • G01J3/44
    • G01N21/658B82Y15/00B82Y30/00
    • An electrically driven device (10) for surface enhanced Raman spectroscopy includes a first electrode (16), a substrate (12) positioned proximate to the first electrode (16), a plurality of cone shaped protrusions (12′) formed integrally with or on a substrate surface (S), a Raman signal-enhancing material (14) coated on each protrusion (12′), and a second electrode (18) positioned relative to the first electrode (16) at a predetermined distance, D. Each of the protrusions (12′) has a tip (22) with a radius of curvature, r, ranging from about 0.1 nm to about 100 nm. The second electrode (18) is positioned relative to the first electrode (16) such that the electrodes (16, 18) together produce an electric field (EF) when a voltage bias is applied therebetween. The electric field (EF) has a field distribution that creates a stronger field gradient at a region proximate to the tips (22) than at other portions of the substrate (12).
    • 用于表面增强拉曼光谱的电驱动装置(10)包括第一电极(16),靠近第一电极(16)定位的基板(12),与该第一电极(16)一体形成的多个锥形突起 涂覆在每个突起(12')上的衬底表面(S),拉曼信号增强材料(14)和相对于第一电极(16)以预定距离D定位的第二电极(D)。 突起(12')具有从约0.1nm至约100nm范围内的具有曲率半径r的尖端(22)。 第二电极(18)相对于第一电极(16)定位,使得当施加电压时,电极(16,18)一起产生电场(EF)。 电场(EF)具有在靠近尖端(22)的区域处比在衬底(12)的其它部分处产生更强的场梯度的场分布。
    • 79. 发明申请
    • Raman signal-enhancing structures for Raman spectroscopy and methods for performing Raman spectroscopy
    • 用于拉曼光谱的拉曼信号增强结构和用于进行拉曼光谱的方法
    • US20080180662A1
    • 2008-07-31
    • US11701045
    • 2007-01-31
    • Shih-Yuan WangZhiyong Li
    • Shih-Yuan WangZhiyong Li
    • G01J3/44
    • G01J3/44G01N21/658
    • Raman systems include a radiation source, a radiation detector configured to detect Raman scattered radiation, and a Raman signal-enhancing structure. The Raman signal-enhancing structure includes a first layer of Raman signal-enhancing material, a substantially monomolecular layer of molecules disposed on at least a portion of the first layer of Raman signal-enhancing material, and a second layer of Raman signal-enhancing material disposed on at least a portion of the substantially monomolecular layer of molecules. The second layer of Raman signal-enhancing material is disposed on a side of the layer of molecules opposite the first layer of Raman signal-enhancing material. Methods of performing Raman spectroscopy include providing such a Raman signal-enhancing structure, providing an analyte on the Raman signal-enhancing structure, irradiating the analyte and the structure, and detecting Raman scattered radiation.
    • 拉曼系统包括辐射源,被配置为检测拉曼散射辐射的辐射检测器和拉曼信号增强结构。 拉曼信号增强结构包括第一层拉曼信号增强材料,设置在第一层拉曼信号增强材料的至少一部分上的基本上单分子层的分子,以及第二层拉曼信号增强材料 设置在分子的基本单分子层的至少一部分上。 第二层拉曼信号增强材料设置在与第一层拉曼信号增强材料相对的分子层的一侧。 执行拉曼光谱的方法包括提供这样的拉曼信号增强结构,在拉曼信号增强结构上提供分析物,照射分析物和结构,以及检测拉曼散射辐射。