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71. 发明授权

US09567571B2 Hepatitis B virus mutant, mutant amplification kit and use thereof 有权
标题翻译：乙型肝炎病毒突变体，突变型扩增试剂盒及其用途
公开(公告)号：US09567571B2
公开(公告)日：2017-02-14
申请号：US14360931
申请日：2012-02-14
申请人： Zhi Chen
发明人： Zhi Chen
IPC分类号： C12N7/00 , C12P19/34 , C12Q1/70
CPC分类号： C12N7/00 , C12N2710/00021 , C12N2730/10121 , C12P19/34 , C12Q1/706 , C12Q2600/156
摘要： The present invention relates to the field of biotechnology, and discloses a hepatitis B virus mutant, a mutant amplification kit and use thereof. The HBV mutant of the invention takes place mutation of the hepatitis B virus mutant in genome sequence No. 216 and/or 285, the mutation occurred at position 216 is that base T mutates to C, the mutation occurred at position 285 is that base G mutates to A. The two mutations are closely related to the inflammation aggravation of the hepatitis B. The invention further provides a HBV mutant amplification kit to detect the above mutation, the usage of the kit and its application, therefore offering help for the clinical early diagnosis and intervention of severe hepatitis B, and providing references for further studying the functional changes caused by HBV gene mutation.
摘要翻译：本发明涉及生物技术领域，并公开了乙型肝炎病毒突变体，突变型扩增试剂盒及其应用。本发明的HBV突变体在基因组序列216和/或285中发生乙型肝炎病毒突变体的突变，在位置216发生的突变是基因T突变为C，位置285处的突变是基G 突变为A.两种突变与乙型肝炎的炎症加重密切相关。本发明还提供了用于检测上述突变的HBV突变扩增试剂盒，该试剂盒的用途及其应用，因此为临床早期提供了帮助诊断和干预重型乙型肝炎，为进一步研究HBV基因突变引起的功能变化提供依据。

72. 发明申请

US20150370473A1 USING A SYMBOL RECOGNITION ENGINE 审中-公开
标题翻译：使用符号识别引擎
公开(公告)号：US20150370473A1
公开(公告)日：2015-12-24
申请号：US14410361
申请日：2012-06-27
申请人： Zhigang Chen , Yong Li , Yunjian Zou , Zhi Chen
发明人： Zhigang Chen , Yong Li , Yunjian Zou , Zhi Chen
IPC分类号： G06F3/0488 , G06F1/16
CPC分类号： G06F3/04883 , G06F1/1626 , G06F1/1637 , G06F3/04886
摘要： A method comprises receiving signals indicative of receipt of a dynamic input by a touch-sensitive transducer, the dynamic input defining a path on the touch-sensitive transducer, at least a first portion of the path being within a first region of the touch-sensitive transducer. The method further comprises determining if a second portion of the path of the dynamic input is within a second region of the touch-sensitive transducer, in response to determining that the second portion path of the dynamic input is within the second region of the display, using a symbol recognition engine to identify a command based on the path of the dynamic input, and causing an action to be performed based on the identified command.
摘要翻译：一种方法包括接收指示由触敏传感器接收动态输入的信号，所述动态输入限定所述触敏传感器上的路径，所述路径的至少第一部分在所述触摸敏感的第一区域内传感器。响应于确定动态输入的第二部分路径在显示器的第二区域内，该方法还包括确定动态输入的路径的第二部分是否在触敏传感器的第二区域内，使用符号识别引擎基于动态输入的路径来识别命令，并且基于所识别的命令使得执行动作。

73. 发明申请

US20150284690A1 HEPATITIS B VIRUS MUTANT, MUTANT AMPLIFICATION KIT AND USE THEREOF 有权
标题翻译：乙型肝炎病毒突变体，突变体扩增试剂盒及其用途
公开(公告)号：US20150284690A1
公开(公告)日：2015-10-08
申请号：US14360931
申请日：2012-02-14
申请人： Zhi Chen
发明人： Zhi Chen
IPC分类号： C12N7/00 , C12Q1/70 , C12P19/34
CPC分类号： C12N7/00 , C12N2710/00021 , C12N2730/10121 , C12P19/34 , C12Q1/706 , C12Q2600/156
摘要： The present invention relates to the field of biotechnology, and discloses a hepatitis B virus mutant, a mutant amplification kit and use thereof. The HBV mutant of the invention takes place mutation of the hepatitis B virus mutant in genome sequence No. 216 and/or 285, the mutation occurred at position 216 is that base T mutates to C, the mutation occurred at position 285 is that base G mutates to A. The two mutations are closely related to the inflammation aggravation of the hepatitis B. The invention further provides a HBV mutant amplification kit to detect the above mutation, the usage of the kit and its application, therefore offering help for the clinical early diagnosis and intervention of severe hepatitis B, and providing references for further studying the functional changes caused by HBV gene mutation.
摘要翻译：本发明涉及生物技术领域，并公开了乙型肝炎病毒突变体，突变型扩增试剂盒及其应用。本发明的HBV突变体在基因组序列216和/或285中发生乙型肝炎病毒突变体的突变，在位置216发生的突变是基因T突变为C，位置285处的突变是基G 突变为A.两种突变与乙型肝炎的炎症加重密切相关。本发明还提供了用于检测上述突变的HBV突变扩增试剂盒，该试剂盒的用途及其应用，因此为临床早期提供了帮助诊断和干预重型乙型肝炎，为进一步研究HBV基因突变引起的功能变化提供依据。

74. 发明授权

US08912246B2 Crosslinkable curing super-branched polyester and cured product and preparation method thereof 有权
标题翻译：可交联固化超支化聚酯和固化产物及其制备方法
公开(公告)号：US08912246B2
公开(公告)日：2014-12-16
申请号：US13885399
申请日：2010-11-15
申请人： Mingdong Yu , Zhi Chen
发明人： Mingdong Yu , Zhi Chen
IPC分类号： C08G61/04 , C08G63/06 , C08G83/00 , C08G63/664 , C08G63/91
CPC分类号： C08G63/664 , C08G63/06 , C08G63/912 , C08G83/005
摘要： A crosslinkable curing super-branched polyester and the cured product and the preparation method thereof are disclosed. The super-branched polyester has high refractive index and comprises a compound represented by the following structural formula (I). In the formula (I), HBP is the backbone of the super-branched polyester; both a and b are positive integers; the sum of a and b is less than or equal to n; n is more than or equal to 10 and less than 80. In the super-branched polyester, A is represented by formula (II) and N is represented by formula (III), wherein R is methyl or hydrogen atom; the mole ratio of N relative to the total mole of A and N is more than 30 mol %, and the ratio of the total mole of A and N relative to the product of the total mole of HBP backbone and n is more than 0.5 and less than or equal to 1.
摘要翻译：公开了一种可交联固化的超支化聚酯和固化产物及其制备方法。超支化聚酯具有高折射率，并且包含由以下结构式（I）表示的化合物。在式（I）中，HBP是超支化聚酯的主链; a和b都是正整数; a和b的和小于或等于n; 在超支化聚酯中，A由式（II）表示，N由式（III）表示，其中R是甲基或氢原子; N相对于A和N的总摩尔数的摩尔比大于30mol％，A和N的总摩尔数相对于HBP主链和n的总摩尔数的乘积的比率大于0.5，小于或等于1。

75. 发明授权

US08034784B2 Method of suppressing or reducing IL-TIF-induced inflammation, or treating associated conditions thereof, using Zcytor16 有权
标题翻译：使用Zcytor16抑制或减少IL-TIF诱导的炎症或治疗其相关病症的方法
公开(公告)号：US08034784B2
公开(公告)日：2011-10-11
申请号：US12620059
申请日：2009-11-17
申请人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
发明人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
IPC分类号： A61K38/16 , A61K39/00
CPC分类号： C07K14/715 , A61K38/00 , C07K2319/00
摘要： Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16” and uses thereof.
摘要翻译：细胞因子及其受体已被证明在基础研究和治疗方面都是有用的。本发明提供了称为“Zcytor16”的新的人细胞因子受体及其应用。

76. 发明授权

US07923208B2 Human cytokine receptor 有权
标题翻译：人类细胞因子受体
公开(公告)号：US07923208B2
公开(公告)日：2011-04-12
申请号：US11670180
申请日：2007-02-01
申请人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
发明人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
IPC分类号： G01N33/53
CPC分类号： C07K14/715 , A61K38/00 , C07K2319/00
摘要： Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”
摘要翻译：细胞因子及其受体已被证明在基础研究和治疗方面都是有用的。本发明提供了称为“Zcytor16”的新的人细胞因子受体。

77. 发明申请

US20100099850A1 HUMAN CYTOKINE RECEPTOR 有权
标题翻译：人体细胞因子受体
公开(公告)号：US20100099850A1
公开(公告)日：2010-04-22
申请号：US12573046
申请日：2009-10-02
申请人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
发明人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
IPC分类号： C07K14/54 , C07K14/00 , C07K16/00
CPC分类号： C07K14/715 , A61K38/00 , C07K2319/00
摘要： Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”
摘要翻译：细胞因子及其受体已被证明在基础研究和治疗方面都是有用的。本发明提供了称为“Zcytor16”的新的人细胞因子受体。

78. 发明申请

US20090249004A1 DATA CACHING FOR DISTRIBUTED EXECUTION COMPUTING 有权
标题翻译：数据缓存用于分布式执行计算
公开(公告)号：US20090249004A1
公开(公告)日：2009-10-01
申请号：US12055777
申请日：2008-03-26
申请人： Taifeng Wang , Tie-Yan Liu , Minghao Liu , Zhi Chen
发明人： Taifeng Wang , Tie-Yan Liu , Minghao Liu , Zhi Chen
IPC分类号： G06F12/00
CPC分类号： G06F12/0875 , G06F17/30902 , G06F17/30958
摘要： Embodiments for caching and accessing Directed Acyclic Graph (DAG) data to and from a computing device of a DAG distributed execution engine during the processing of an iterative algorithm. In accordance with one embodiment, a method includes processing a first subgraph of the plurality of subgraphs from the distributed storage system in the computing device. The first subgraph being processed with associated input values in the computing device to generate first output values in an iteration. The method further includes storing a second subgraph in a cache of the device. The second subgraph being a duplicate of the first subgraph. Moreover, the method also includes processing the second subgraph with the first output values to generate second output values if the device is to process the first subgraph in each of one or more subsequent iterations.
摘要翻译：用于在迭代算法的处理期间向DAG分布式执行引擎的计算设备缓存和访问定向非循环图（DAG）数据的实施例。根据一个实施例，一种方法包括从计算设备中的分布式存储系统处理多个子图的第一子图。在计算设备中用相关联的输入值处理第一子图，以在迭代中生成第一输出值。该方法还包括将第二子图存储在设备的高速缓存中。第二个子图是第一个子图的副本。此外，该方法还包括用第一输出值处理第二子图以产生第二输出值，如果该设备要在一个或多个后续迭代中的每一个中处理第一子图。

79. 发明授权

US07534575B2 Method for detecting cancer using an antibody to Zcytor16 有权
标题翻译：使用Zcytor16抗体检测癌症的方法
公开(公告)号：US07534575B2
公开(公告)日：2009-05-19
申请号：US11670209
申请日：2007-02-01
申请人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
发明人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
IPC分类号： G01N33/53
CPC分类号： C07K14/715 , A61K38/00 , C07K2319/00
摘要： Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”
摘要翻译：细胞因子及其受体已被证明在基础研究和治疗方面都是有用的。本发明提供了称为“Zcytor16”的新的人细胞因子受体。

80. 发明授权

US07491809B2 Polynucleotides encoding human cytokine receptor 有权
标题翻译：编码人细胞因子受体的多核苷酸
公开(公告)号：US07491809B2
公开(公告)日：2009-02-17
申请号：US11534706
申请日：2006-09-25
申请人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
发明人： Scott R. Presnell , Wenfeng Xu , Wayne Kindsvogel , Zhi Chen
IPC分类号： C07H21/04 , C12N15/63 , C12N1/21 , C12N5/10
CPC分类号： C07K14/715 , A61K38/00 , C07K2319/00
摘要： Cytokines and their receptors have proven usefulness in both basic research and as therapeutics. The present invention provides a new human cytokine receptor designated as “Zcytor16.”
摘要翻译：细胞因子及其受体已被证明在基础研究和治疗方面都是有用的。本发明提供了称为“Zcytor16”的新的人细胞因子受体。

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