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71. 发明授权

US5294626A Arylsulphonamides pharmaceutical compositions containing these compounds 失效
标题翻译：含有这些化合物的芳基磺酰胺药物组合物
公开(公告)号：US5294626A
公开(公告)日：1994-03-15
申请号：US523167
申请日：1990-05-14
申请人： Armin Heckel , Josef Nickl, deceased , Rainer Soyka , Wolfgang Eisert , Thomas Muller , Johannes Weisenberger , Christopher Meade , Gojko Muacevic
发明人： Armin Heckel , Josef Nickl, deceased , Rainer Soyka , Wolfgang Eisert , Thomas Muller , Johannes Weisenberger , Christopher Meade , Gojko Muacevic
IPC分类号： C07D213/55 , A61K31/145 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/4418 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61P7/02 , A61P9/00 , A61P9/10 , A61P11/00 , A61P37/08 , A61P43/00 , C07D213/56 , C07D401/06 , C07D405/06 , C07D409/06 , C07D409/10 , C07D409/12 , C07D409/14
CPC分类号： C07D401/06 , C07D213/55 , C07D213/56 , C07D409/06 , C07D409/12
摘要： The invention relates to new arylsulphonamides of the formula ##STR1## (wherein A, B and R.sub.1 to R.sub.6 are as defined in claim 1, the enantiomers, the cis- and trans-isomers thereof where R.sub.4 and R.sub.5 together represent a carbon-carbon bond, and the addition salts thereof, more particularly for pharmaceutical use the physiologically acceptable addition salts thereof with inorganic or organic bases, if R.sub.6 represents a hydroxy group) which have useful pharmacological properties, particularly antithrombotic activities and thromboxane-mediating activities. Furthermore, the new compounds are also thromboxane antagonists (TRA) and thromboxane synthesis inhibitors (TSH) They also have an effect on PGE.sub.2 production.
摘要翻译：本发明涉及新的式（I）芳基磺酰胺（其中A，B和R 1至R 6如权利要求1中所定义，其对映异构体，顺式和反式异构体，其中R 4和R 5一起代表碳碳键和其加成盐，更特别是药物用途，其与无机或有机碱的生理上可接受的加成盐，如果R6表示羟基），其具有有用的药理学特性，特别是抗血栓形成活性和血栓烷烷介导活性。此外，新化合物也是血栓烷拮抗剂（TRA）和血栓烷合成抑制剂（TSH）。它们也对PGE2产生影响。

72. 发明授权

US4991696A Brake shoe adjustment device 失效
标题翻译：制动鞋调节装置
公开(公告)号：US4991696A
公开(公告)日：1991-02-12
申请号：US419081
申请日：1989-10-06
申请人： Manfred Minning , Thomas Muller
发明人： Manfred Minning , Thomas Muller
IPC分类号： F16D65/46
CPC分类号： F16D65/46
摘要： A brake shoe adjustment device for internally mounted shoe brakes is arranged between mutually neighboring ends of two brake shoes which are connected to each other via a tension spring. To minimize parts, size and cost the adjustment device has two mutually opposite spreading elements, each of which is held by one brake shoe end. One of the elements is equipped with a threaded shank that cooperates with a threaded bore of the other element. The elements are axially displaceable by a worm wheel gear which rotates the shank in response to turning by an adjusting tool.
摘要翻译：用于内部安装的制动器的制动瓦调节装置布置在两个通过拉伸弹簧相互连接的制动蹄的相邻端之间。为了最小化部件，尺寸和成本，调节装置具有两个相互相对的扩展元件，每个扩展元件由一个制动蹄端保持。元件中的一个装备有与另一元件的螺纹孔配合的螺纹柄。这些元件可以通过蜗杆齿轮轴向移动，该蜗轮齿轮响应于由调节工具转动而旋转柄。

73. 外观设计

USD293008S Octagonal ball court 失效
公开(公告)号：USD293008S
公开(公告)日：1987-12-01
申请号：US661215
申请日：1984-10-15
申请人： Thomas Muller
设计人： Thomas Muller

74. 发明授权

US08286221B2 Security architecture 有权
标题翻译：安全架构
公开(公告)号：US08286221B2
公开(公告)日：2012-10-09
申请号：US11275964
申请日：2006-02-07
申请人： Thomas Muller , Martin Roter
发明人： Thomas Muller , Martin Roter
IPC分类号： H04L29/06
CPC分类号： H04L63/0428 , H04L63/08 , H04L63/162 , H04W12/06 , H04W88/18
摘要： A device for communicating with other devices to allow them to access applications, comprises: at least a first application; authentication means for authenticating a communicating device; and access control means accessible by a communicating device requesting access to the first application without the communicating device having been authenticated by the authentication means. The device is further arranged to arbitrate whether access of the communicating device to the first application is granted or refused wherein if the arbitration requires an authentication of the communicating device, the access control means instructs the authentication means to authenticate the communicating device.
摘要翻译：用于与其他设备进行通信以允许其访问应用的设备包括：至少第一应用; 用于认证通信设备的认证装置; 以及访问控制装置，其可由通信装置访问，请求对第一应用的访问，而通信装置未被认证装置认证。所述设备还被布置为仲裁所述通信设备对所述第一应用的访问是否被许可或拒绝，其中如果所述仲裁需要所述通信设备的认证，则所述访问控制单元指示所述认证单元认证所述通信设备。

75. 发明申请

US20120003752A1 Prognostic biomarkers for the progression of primary chronic kidney disease 有权
标题翻译：原发性慢性肾脏疾病进展的预后生物标志物
公开(公告)号：US20120003752A1
公开(公告)日：2012-01-05
申请号：US13125631
申请日：2009-10-22
申请人： Joachim Struck , Benjamin Dieplinger , Thomas Muller , Barbara Kollerits , Florian Kronenberg
发明人： Joachim Struck , Benjamin Dieplinger , Thomas Muller , Barbara Kollerits , Florian Kronenberg
IPC分类号： G01N33/566
CPC分类号： G01N33/74 , G01N2333/58 , G01N2800/347
摘要： Subject of the present invention are assays and in vitro methods for prediction of the progression of primary chronic kidney disease (CKD) or for monitoring chronic kidney disease therapy comprising the determination of the level of ANP and/or ADM or its precursors or fragments thereof.
摘要翻译：本发明的主题是用于预测原发性慢性肾脏病（CKD）进展或用于监测慢性肾脏疾病治疗的测定和体外方法，包括测定ANP和/或ADM或其前体或其片段的水平。

76. 发明授权

US07786080B2 Mutein of a bone morphogenetic protein and use thereof 失效
标题翻译：骨形态发生蛋白的突变蛋白及其用途
公开(公告)号：US07786080B2
公开(公告)日：2010-08-31
申请号：US10591482
申请日：2005-03-04
申请人： Thomas Muller , Walter Sebald
发明人： Thomas Muller , Walter Sebald
IPC分类号： A61K38/18 , C07K14/51
CPC分类号： C07K14/51 , A61K38/00
摘要： The present invention is related to a mutein of a bone morphogenetic protein, whereby the mutein comprises an amino acid substitution compared to the wildtype of the bone morphogenetic protein at the amino acid position corresponding to amino acid position 51 of human BMP-2.
摘要翻译：本发明涉及骨形态发生蛋白的突变蛋白，其中与对应于人BMP-2的氨基酸位置51的氨基酸位置处的骨形态发生蛋白的野生型相比，突变蛋白包含氨基酸取代。

77. 发明申请

US20100010967A1 SYSTEM AND METHOD FOR A LOG-BASED DATA STORAGE 有权
标题翻译：用于基于日志的数据存储的系统和方法
公开(公告)号：US20100010967A1
公开(公告)日：2010-01-14
申请号：US12172971
申请日：2008-07-14
申请人： Thomas Muller
发明人： Thomas Muller
IPC分类号： G06F17/30 , G06F7/06
CPC分类号： G06F17/30587
摘要： Embodiments of the invention provide a high-performance content management system with a log-based data storage. To speed data operations, updates and deletes are appended to log-based data files. Seek operations are not needed as old data is not overwritten or removed at the time of write operations. Instead, the log-based data files are periodically optimized by processes that compact data entries and remove data files containing old data. In addition, an associated index with entries accessible in constant time is used to facilitate the process of locating data entries within the data files. Embodiments of the log-based data storage are implemented in a standard file format for ease of development and maintenance and can be compressed to further improve performance. In one embodiment, the log-based data storage corresponds to a node-based logical data tree that can be adapted to house a variety of data, including data from relational databases.
摘要翻译：本发明的实施例提供了一种具有基于日志的数据存储的高性能内容管理系统。为了加速数据操作，更新和删除将附加到基于日志的数据文件。不需要寻求操作，因为在写入操作时旧数据不会被覆盖或删除。相反，基于日志的数据文件由压缩数据条目和删除包含旧数据的数据文件的进程定期优化。此外，使用具有可在常量时间访问的条目的关联索引来促进在数据文件内定位数据条目的过程。基于日志的数据存储的实施例以标准文件格式实现，以便于开发和维护，并且可以被压缩以进一步提高性能。在一个实施例中，基于日志的数据存储对应于可以适于容纳各种数据（包括来自关系数据库的数据）的基于节点的逻辑数据树。

78. 发明申请

US20080213072A1 Discharge hopper and method of discharging shaft trays filled with rod-shaped products 失效
标题翻译：排料斗和排出装有棒状产品的轴托盘的方法
公开(公告)号：US20080213072A1
公开(公告)日：2008-09-04
申请号：US12068080
申请日：2008-02-01
申请人： Piotr Budny , Thomas Muller , Matthias Horn , Michael Knabe , Arnd Meier
发明人： Piotr Budny , Thomas Muller , Matthias Horn , Michael Knabe , Arnd Meier
IPC分类号： B65G47/04 , B65G65/30 , B65D88/32 , B65G47/74 , B65G3/04
CPC分类号： A24C5/356 , A24C5/358 , B65B19/04
摘要： A discharge hopper for a tray discharge station for serially discharging shaft trays filled with rod-shaped products includes, a conveying element for carrying away the products flowing from the shaft trays and a connecting device for coupling the shaft trays to be emptied to the conveying element. The connecting device is arranged substantially parallel to and spaced apart from the conveying element to form a channel for the product flow and includes an opening for passage of the products from the shaft tray into the channel. In the region of the connecting device there is provided a closure unit to open and close the opening. The closure device is coupled to a movable actuating element so that the closure device can be opened and closed shaft by shaft in relation to the shaft tray to be emptied.
摘要翻译：用于串联排出装有棒状产品的轴托盘的托盘排放站的排出料斗包括用于运送从轴托盘流出的产品的输送元件和用于联接要被排空到输送元件的轴托盘的连接装置。连接装置被布置成基本上与输送元件平行并间隔开，以形成用于产品流动的通道，并且包括用于将产品从轴托盘通入通道的开口。在连接装置的区域中，设置有用于打开和关闭开口的封闭单元。闭合装置联接到可移动的致动元件，使得封闭装置可以相对于要被排空的轴托盘被轴打开和关闭。

79. 发明申请

US20080181754A1 Discharge hopper and method of discharing trays, in particular shaft trays, filled with rod-shaped articles 审中-公开
标题翻译：排料斗和排料托盘的方法，特别是装有杆状制品的轴托盘
公开(公告)号：US20080181754A1
公开(公告)日：2008-07-31
申请号：US12010992
申请日：2008-01-31
申请人： Piotr Budny , Thomas Muller , Matthias Horn , Michael Knabe , Arnd Meier
发明人： Piotr Budny , Thomas Muller , Matthias Horn , Michael Knabe , Arnd Meier
IPC分类号： B65G65/00
CPC分类号： A24C5/356 , B65G43/08 , B65G47/19
摘要： A discharge hopper for a tray discharge station discharges a tray filled with rod-shaped products. A receiving chamber for the products flowing from the tray is open at the top in the direction of the tray and at the bottom is defined by a channel formed by a conveying element that carries away the products. Flow regulating elements within the receiving chamber control the flow of products within the discharge hopper. A monitoring unit is arranged and constructed for detecting the level of products within the tray. The monitoring unit is operatively connected to the flow regulating elements for individual control of the flow regulating elements.
摘要翻译：用于托盘排出站的排出料斗排出填充有棒状产品的托盘。用于从托盘流出的产品的接收室在托盘的顶部处是敞开的，并且底部由通过输送元件形成的通道限定，该输送元件带走产品。接收室内的流量调节元件控制排出料斗内的产品流。布置和构造监测单元以检测托盘内的产品的水平。监测单元可操作地连接到流量调节元件，用于单独控制流量调节元件。

80. 发明申请

US20080039121A1 Methods and Systems for Establishing Relationships Between Mobile Communication Device Users 审中-公开
标题翻译：建立移动通信设备用户关系的方法与系统
公开(公告)号：US20080039121A1
公开(公告)日：2008-02-14
申请号：US11831959
申请日：2007-08-01
申请人： Thomas Muller , Jan Schulz , Lars Henrik Grau , Marhus Juhr-De Benedetti
发明人： Thomas Muller , Jan Schulz , Lars Henrik Grau , Marhus Juhr-De Benedetti
IPC分类号： H04M3/42 , G06F7/00
CPC分类号： H04M7/0036 , H04M2203/655
摘要： A method of establishing a community including a first mobile communication device user and a second mobile communication device user is disclosed. The method includes receiving a first message from the first mobile communication device user and receiving a second message from the second mobile communication device user. The method further includes parsing the first message and the second message to determine a first user identifier and a first user-generated key and a second user identifier and a second user-generated key respectively. Furthermore, the method includes calculating a matching probability between the first mobile communication device user and the second mobile communication device user based on at least one of a proximity of distance, a proximity of time of the receipt of messages, and matching of the user-generated keys.
摘要翻译：公开了一种建立包括第一移动通信设备用户和第二移动通信设备用户的社区的方法。该方法包括从第一移动通信设备用户接收第一消息并从第二移动通信设备用户接收第二消息。该方法还包括分析第一消息和第二消息以分别确定第一用户标识符和第一用户生成的密钥以及第二用户标识符和第二用户生成的密钥。此外，该方法包括基于距离的接近度，接收消息的时间的接近度以及用户级别的匹配中的至少一个来计算第一移动通信设备用户和第二移动通信设备用户之间的匹配概率，生成的键。

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