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71. 发明申请

US20080200879A1 COMPOSITE GUIDEWIRE WITH DRAWN AND FILLED TUBE CONSTRUCTION 有权
标题翻译：复合导轨与抽屉和填充管道结构
公开(公告)号：US20080200879A1
公开(公告)日：2008-08-21
申请号：US12046990
申请日：2008-03-12
申请人： Marc Mehrzad Jalisi , David M. Anderson , Wayne E. Cornish , Nancy A. Nicotra , Mark T. Richardson
发明人： Marc Mehrzad Jalisi , David M. Anderson , Wayne E. Cornish , Nancy A. Nicotra , Mark T. Richardson
IPC分类号： A61M25/09
CPC分类号： A61M25/09 , A61M2025/09175
摘要： The present invention is directed to an intracorporeal device, preferably a guidewire, and method for making the device. The guidewire of the present invention is formed, at least in part, of a composite elongate core formed, at least in part, of precipitation hardened material. The elongate core members of the present invention will have an ultimate tensile strength and modulus of elasticity greater than the same for an identically dimensioned elongate member formed from superelastic NITINOL alone.
摘要翻译：本发明涉及体内装置，优选导丝，以及制造该装置的方法。本发明的导丝至少部分地形成有至少部分由沉淀硬化材料形成的复合细长芯。对于由超弹性NITINOL单独形成的相同尺寸的细长构件，本发明的细长芯构件将具有大于相同尺寸的极限拉伸强度和弹性模量。

72. 发明申请

US20080114506A1 HARD LANDING DETECTION 审中-公开
标题翻译：硬着陆检测
公开(公告)号：US20080114506A1
公开(公告)日：2008-05-15
申请号：US11558815
申请日：2006-11-10
申请人： Christopher L. Davis , Jack S. Hagelin , Jonathan R. LePere , David P. Earle , Richard J. Reuter , Aydin Akdeniz , Eric D. Haugse , David M. Anderson
发明人： Christopher L. Davis , Jack S. Hagelin , Jonathan R. LePere , David P. Earle , Richard J. Reuter , Aydin Akdeniz , Eric D. Haugse , David M. Anderson
IPC分类号： G06F19/00
CPC分类号： G05B13/0265 , B64D2045/008 , G05B23/024
摘要： A method and system for detecting a hard landing or other high load event of an aircraft are disclosed. A heuristic algorithm may be used to estimate loads experienced by the aircraft during landing. The heuristic algorithm may use flight parameters and/or measured sensor information to estimate the loads. The heuristic algorithm may be trained by means of analytical loads predictions and/or test measurements. The heuristic algorithm may be updated during operation. This invention may potentially reduce the number of unnecessary structural inspections, and may also limit the scope of any such required inspections.
摘要翻译：公开了一种用于检测飞机的硬着陆或其他高负载事件的方法和系统。启发式算法可用于估计飞机在着陆期间经历的载荷。启发式算法可以使用飞行参数和/或测量的传感器信息来估计负载。可以通过分析负载预测和/或测试测量来训练启发式算法。启发式算法可能在操作期间被更新。本发明可能潜在地减少不必要的结构检查的数量，并且还可以限制任何这种所需检查的范围。

73. 发明授权

US07281318B2 Method of manufacturing a composite structural member having an integrated electrical circuit 有权
标题翻译：制造具有集成电路的复合结构件的方法
公开(公告)号：US07281318B2
公开(公告)日：2007-10-16
申请号：US10848703
申请日：2004-05-19
申请人： Joseph A. Marshall , Douglas B. Weems , Richard C. Bussom , David M. Anderson
发明人： Joseph A. Marshall , Douglas B. Weems , Richard C. Bussom , David M. Anderson
IPC分类号： H01C17/28
CPC分类号： H05K3/103 , B29C35/0272 , B29C70/86 , B29C70/885 , B64C27/473 , B64C2027/7283 , H05K3/0058 , H05K3/281 , H05K2201/10151 , H05K2201/1028 , Y02T50/34 , Y10T29/49082 , Y10T29/49083 , Y10T29/49085 , Y10T29/49087 , Y10T29/49099 , Y10T29/49101 , Y10T29/49117 , Y10T29/49155 , Y10T428/24942
摘要： A method of manufacturing a composite structural member with an integrated electrical circuit is provided. The structural member includes a plurality of layers of structural reinforcement material, and two or more electrical devices are disposed at least partially between the layers with an intermediate layer of the structural reinforcement material disposed between the electrical devices. At least one electrical bus is disposed in the structural member, and each electrical device is connected to the bus by a conductive electrode. Thus, the electrodes can extend through the intermediate layer of the structural reinforcement material to connect each of the electrical devices to one or more of the buses.
摘要翻译：提供一种制造具有集成电路的复合结构件的方法。结构构件包括多层结构增强材料，并且两个或更多个电气装置至少部分地设置在层之间，其中结构增强材料的中间层设置在电气装置之间。至少一个电气总线设置在结构构件中，并且每个电气装置通过导电电极连接到总线。因此，电极可以延伸穿过结构增强材料的中间层，以将每个电气设备连接到一个或多个总线。

74. 发明授权

US07157617B2 Methods for producing pesticidal cotton plants expressing lectins 有权
标题翻译：表达凝集素的杀虫棉花植物的生产方法
公开(公告)号：US07157617B2
公开(公告)日：2007-01-02
申请号：US10446608
申请日：2003-05-27
申请人： Richard L. Yenofsky , Miriam Fine , Thirumale S. Rangan , David M. Anderson
发明人： Richard L. Yenofsky , Miriam Fine , Thirumale S. Rangan , David M. Anderson
IPC分类号： C12N15/00 , C12N15/82 , A01H5/00
CPC分类号： C12N15/8286 , A01N65/08 , A01N65/44 , C07K14/42 , C12N15/8282 , C12N15/8285 , Y02A40/162 , Y02A40/164
摘要： Methods of producing pesticidal cotton cells, cotton plants and seeds by transformation with heterologous pesticidal lectin encoding nucleic acid sequences are disclosed.
摘要翻译：公开了通过异源农药凝集素编码核酸序列转化生产杀虫棉花细胞，棉花植物和种子的方法。

75. 发明授权

US07018217B2 Structurally integrable electrode and associated assembly and fabrication method 有权
标题翻译：结构可积分电极及相关装配及制造方法
公开(公告)号：US07018217B2
公开(公告)日：2006-03-28
申请号：US10848655
申请日：2004-05-19
申请人： Joseph A. Marshall , David M. Anderson
发明人： Joseph A. Marshall , David M. Anderson
IPC分类号： H01R12/00 , H05K1/00
CPC分类号： B32B3/08 , B32B7/12 , B32B27/08 , B32B27/281 , B32B2250/24 , B32B2307/206 , B32B2457/00 , B64D43/00 , H05K3/10 , H05K3/28 , H05K2201/029
摘要： A structurally integrable electrode, an assembly with an integrated electrode, and an associated method are provided. The electrode is configured to provide an electrically conductive path between nodes of an electrical circuit of a structural member. In particular, the electrode includes at least one conductive tow having a core and a conductive coating thereon. Electrically conductive contacts are connected to the ends of the tow, and at least one dielectric ply extends parallel to the tow to at least partially insulate the tow. Thus, the first and second contacts can be connected to the nodes of the circuit, and the tow can be structurally integrated with the structural member so that the tow provides an electrically conductive path between the nodes.
摘要翻译：提供了结构可积分电极，具有集成电极的组件和相关联的方法。电极被配置为在结构构件的电路的节点之间提供导电路径。特别地，电极包括至少一个具有芯和其上的导电涂层的导电丝束。导电触点连接到丝束的端部，并且至少一个电介质层平行于丝束延伸以使丝束至少部分绝缘。因此，第一和第二触点可以连接到电路的节点，并且丝束可以在结构上与结构构件一体化，使得丝束在节点之间提供导电路径。

76. 发明授权

US06624344B1 Transformation of cotton plants 失效
标题翻译：棉花植物转化
公开(公告)号：US06624344B1
公开(公告)日：2003-09-23
申请号：US08480186
申请日：1995-06-07
申请人： Thirumale S. Rangan , David M. Anderson , Kanniah Rajasekaran , John W. Grula , Richard Lorne Hudspeth , Richard L. Yenofsky
发明人： Thirumale S. Rangan , David M. Anderson , Kanniah Rajasekaran , John W. Grula , Richard Lorne Hudspeth , Richard L. Yenofsky
IPC分类号： C12N1582
CPC分类号： A01H5/10 , A01H1/02 , A01H4/001 , A01H4/005 , A01H4/008 , C07K14/325 , C12N5/04 , C12N15/8205 , C12N15/8222 , C12N15/8223 , C12N15/8275 , C12N15/8286 , Y02A40/162
摘要： A method for producing transformed cotton plants. The method comprising providing cotton explants, incubating the cotton explant in the presence of a vector comprising a selectable marker to produce treated explants, growing the treated explants to produce callus and selecting transformed callus.
摘要翻译：一种生产转化棉花植物的方法。该方法包括提供棉花外植体，在包含选择性标记的载体存在下孵育棉花外植体以产生经处理的外植体，培养经处理的外植体以产生愈伤组织并选择转化的愈伤组织。

77. 发明授权

US06620990B1 Transformation of cotton plants 失效
公开(公告)号：US06620990B1
公开(公告)日：2003-09-16
申请号：US08122090
申请日：1993-09-14
申请人： Thirumale S. Rangan , David M. Anderson , Kanniah Rajasekaran , John W. Grula , Richard Lorne Hudspeth , Richard L. Yenofsky
发明人： Thirumale S. Rangan , David M. Anderson , Kanniah Rajasekaran , John W. Grula , Richard Lorne Hudspeth , Richard L. Yenofsky
IPC分类号： C12N1582
CPC分类号： A01H5/10 , A01H1/02 , A01H4/001 , A01H4/005 , A01H4/008 , C07K14/325 , C12N5/04 , C12N15/8205 , C12N15/8222 , C12N15/8223 , C12N15/8275 , C12N15/8286 , Y02A40/162
摘要： A method for producing transformed cotton plants. The method comprising providing cotton explants, incubating the cotton explant in the presence of a vector comprising a selectable marker to produce treated explants, growing the treated explants to produce callus and selecting transformed callus.

78. 发明授权

US06491648B1 Guidewire with tapered flexible core segment 有权
标题翻译：导丝带锥形柔性芯段
公开(公告)号：US06491648B1
公开(公告)日：2002-12-10
申请号：US09748299
申请日：2000-12-21
申请人： Wayne E. Cornish , Mark T. Richardson , Lawrence E. Brennan , Marc M. Jalisi , David M. Anderson , Mo Jafari , Sepehr Fariabi
发明人： Wayne E. Cornish , Mark T. Richardson , Lawrence E. Brennan , Marc M. Jalisi , David M. Anderson , Mo Jafari , Sepehr Fariabi
IPC分类号： A61B500
CPC分类号： A61M25/09 , A61M2025/09175
摘要： A guidewire for guiding a medical device within a patient which has an elongate core member with a flexible body member disposed about and secured to a distal core section and a flexible core segment or flexible core segment which has a first pair of opposed faces which define a first transverse dimension that tapers from a first value to a second larger value and a second pair of opposed faces which define a second transverse dimension that tapers from a first value to a second smaller value.
摘要翻译：一种用于在具有细长芯部件的患者体内引导医疗装置的导丝，其具有设置在远端芯部周围并固定到远端芯部的柔性主体部件以及具有第一对相对面的柔性芯部或柔性芯部，从第一值逐渐变细到第二较大值的第一横向尺寸和限定从第一值到第二较小值逐渐变细的第二横向尺寸的第二对相对面。

79. 发明授权

US06428512B1 Guidewire with improved lesion measurement 有权
标题翻译：导丝具有改善的病变测量
公开(公告)号：US06428512B1
公开(公告)日：2002-08-06
申请号：US09686143
申请日：2000-10-10
申请人： David M. Anderson , Mark T. Richardson , Gina Eileen Stephens
发明人： David M. Anderson , Mark T. Richardson , Gina Eileen Stephens
IPC分类号： A61M2500
CPC分类号： A61M25/09 , A61M2025/0008 , A61M2025/09083 , A61M2025/09166
摘要： A guidewire having an elongated core having a radiopaque marker on a distal portion of the core and a plurality of indicia on the proximal extremity of the core to facilitate measurement of an intracorporeal location such as a stenotic region within a patient's coronary artery. The guidewire is first positioned within the patient with the distal radiopaque marker at one end of the intracorporeal location and an indicia representing a base reference point is noted on the proximal portion of the guidewire which extends out of the patient. The guidewire is then moved so that the distal radiopaque marker is located at or adjacent to the other end of the intracorporeal location and another indicia on the proximal portion of the guidewire adjacent to the reference point. The distance between the two indicia on the proximal extremity of the guidewire is a measurement of intracorporeal length.
摘要翻译：具有细长芯的导丝，其具有在芯的远侧部分上的不透射线的标记，以及在芯的近端上的多个标记，以便于测量体内位置，例如患者冠状动脉内的狭窄区域。首先将导丝线定位在患者体内，在体内位置的一端具有远端不透射线的标记，并且在延伸出患者的导丝的近端部分上注意到表示基准参考点的标记。导线然后被移动，使得远端不透射线的标记物位于或邻近体内位置的另一端，并且在引导线的邻近参考点的近端部分上的另一个标记。导线近端两个标记之间的距离是体内长度的测量。

80. 发明授权

US6146339A Guide wire with operator controllable tip stiffness 有权
标题翻译：导线，操作者可控尖端刚度
公开(公告)号：US6146339A
公开(公告)日：2000-11-14
申请号：US317574
申请日：1999-05-24
申请人： Emmanuel Biagtan , David M. Anderson
发明人： Emmanuel Biagtan , David M. Anderson
IPC分类号： A61B5/00 , A61M25/09
CPC分类号： A61M25/09 , A61M2025/09008 , A61M2025/09133 , A61M2025/0915 , A61M2025/09175
摘要： An improved method and apparatus for providing a readily insertable guide wire that is also accurately steerable. One embodiment of the present invention comprises one or more thin diameter, liquid filled, polymer balloons enclosed by the guide wire coils and connected through a hypotube lumen to a pressure transducer. The pressure transducer exerts pressure via a fluid medium to the balloon(s), which then expand and exert pressure onto the inner surface of the coils, thereby stiffening the distal section of the guide wire. In operation, the guide wire will typically be inserted with the balloons deflated, hence the distal tip is very flexible. Once the distal tip reaches its destination, the balloons are inflated and expanded to stiffen and/or reorient the distal tip to allow it to perform as required, typically by aiding in the positioning of a catheter or stent in the desired location.
摘要翻译：一种改进的方法和设备，用于提供也是可精确控制的易于插入的导丝。本发明的一个实施例包括由导丝线圈包围并通过海波管腔连接到压力传感器的一个或多个细直径的，液体填充的聚合物球。压力传感器通过流体介质将压力施加到球囊上，然后膨胀并施加压力到线圈的内表面上，从而加强导丝的远端部分。在操作中，导丝通常将气囊放气，因此远端尖端非常柔软。一旦远端顶端到达其目的地，气囊就被膨胀和膨胀以加强和/或重新定向远侧末端，以允许其根据需要执行，通常通过辅助将导管或支架定位在期望的位置。

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