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    • 72. 发明申请
    • ARM HEAD
    • ARM头
    • US20120230756A1
    • 2012-09-13
    • US13413337
    • 2012-03-06
    • Toshio ShidoNoboru Ishida
    • Toshio ShidoNoboru Ishida
    • F16C11/04
    • B60S1/345B60S1/3438Y10T403/32951
    • An arm head includes an end portion to which a retainer is pivotally coupled and a surface covered by a coating. The end portion includes a coupling bore. The coupling bore includes an open end. First and second surfaces of the arm head form an annular recess around the open end that extends continuously from the open end. The radial outer surface extends outward in a radial direction from the annular recess. The first surface extends outward in the radial direction from the open end. The first surface is located inward in an axial direction of the coupling bore from the radial outer surface. The second surface extends from the first surface to the radial outer surface at an angle less than 180° with respect to the first surface.
    • 臂头包括端部,保持器可枢转地连接到该端部以及被涂层覆盖的表面。 端部包括联接孔。 联接孔包括开口端。 臂头的第一和第二表面形成围绕开口端的环形凹部,其从开口端连续延伸。 径向外表面从环形凹部径向向外延伸。 第一表面从开口端沿径向向外延伸。 第一表面从径向外表面位于联接孔的轴向方向内侧。 第二表面以相对于第一表面小于180°的角度从第一表面延伸到径向外表面。
    • 74. 发明授权
    • Gas concentration sensor
    • 气体浓度传感器
    • US06892566B2
    • 2005-05-17
    • US10393496
    • 2003-03-21
    • Masashi SakamotoYoshikuni SatoHideki IshikawaKeigo BannoNoboru Ishida
    • Masashi SakamotoYoshikuni SatoHideki IshikawaKeigo BannoNoboru Ishida
    • G01N29/024G01N29/22G01N29/44G01N29/02G01H5/00
    • G01N29/222G01N29/024G01N2291/011G01N2291/015G01N2291/0212G01N2291/0217G01N2291/02809G01N2291/045G01N2291/101
    • A gas concentration sensor includes a measurement chamber for measuring a concentration of a specific gas component in a gas under measurement; an inflow path for allowing inflow of the gas under measurement thereinto and an outflow path for allowing outflow of the gas under measurement therefrom; a reflection wall for reflecting an acoustic wave; and an acoustic wave transmitting-receiving element having a transmitting-receiving surface adapted to transmit an acoustic wave toward the reflection wall and receive an acoustic wave reflected from the reflection wall. The concentration of the specific gas in the gas under measurement is detected on the basis of a propagation time between transmission of the acoustic wave and reception of the reflected acoustic wave. When a predetermined member having the sensor attached thereto is placed in a horizontal plane, the transmitting-receiving surface faces downward. A recess is formed in a peripheral portion of the reflection wall. The recess is receded toward a back surface of the reflection wall, namely, in a direction away from the transmitting-receiving surface.
    • 气体浓度传感器包括用于测量被测气体中特定气体成分浓度的测量室; 用于允许在其中测量气体的流入的流入路径和用于允许从其测量的气体流出的流出路径; 用于反射声波的反射壁; 以及具有发射接收表面的声波发射接收元件,所述发射接收表面适于向反射壁传输声波并接收从反射壁反射的声波。 基于声波的发送和反射声波的接收之间的传播时间来检测被测气体中的比气体的浓度。 当安装有传感器的预定构件放置在水平面中时,发送接收表面向下。 在反射壁的周边部分形成有凹部。 凹部朝向反射壁的后表面,即远离发射接收表面的方向退回。
    • 78. 发明授权
    • Lipid A analogs having immunoactivating and anti-tumor activity
    • 脂质A具有免疫激活和抗肿瘤活性的类似物
    • US5792840A
    • 1998-08-11
    • US280298
    • 1994-07-26
    • Masao ShiozakiNoboru IshidaMasami AraiTetsuo HiraokaTomowo KobayashiYuzuru AkamatsuMasahiro Nishijima
    • Masao ShiozakiNoboru IshidaMasami AraiTetsuo HiraokaTomowo KobayashiYuzuru AkamatsuMasahiro Nishijima
    • C07H5/06A61K31/70C07H11/04C07H13/06C07H13/12C07H15/02C07H15/10C07H15/18C07H5/02C07H13/02
    • C07H13/06C07H13/12C07H15/10C07H5/06
    • Compounds of formula (I): ##STR1## in which: R.sup.1 is hydroxy, protected hydroxy, fluorine, or --OP(O)(OH).sub.2 ; R.sup.2 and R.sup.3 are independently optionally substituted C.sub.6 -C.sub.20 aliphatic acyl; R.sup.4 is hydroxy, protected hydroxy, or --OP(O)(OH).sub.2, where at least one of R.sup.1 and R.sup.4 is --OP(O)(OH).sub.2 ; and R.sup.5 is hydroxy, protected hydroxy, or fluorine; provided that, except where at least one of R.sup.1 and R.sup.5 is fluorine, then at least one of R.sup.2 and R.sup.3 is a substituted C.sub.6 -C.sub.20 aliphatic acyl having (i) at least one halogen substituent and (ii) at least one substituent selected from the group consisting of halogen, hydroxy and C.sub.6 -C.sub.20 aliphatic acyloxy or at least one of R.sup.2 and R.sup.3 is a substituted C.sub.6 -C.sub.20 aliphatic acyl which is substituted by at least one halogen-substituted C.sub.6 -C.sub.20 aliphatic carboxylic acyloxy; have Lipid A-like activity and may be used for the treatment, prophylaxis, diagnosis and support of an animal suffering a disease or disorder arising from a deficiency in the immune system or from a tumor. They may be prepared by phosphorylation of corresponding compounds lacking a phosphoryl group.
    • 式(I)化合物:其中:R 1是羟基,被保护的羟基,氟或-OP(O)(OH)2; R2和R3独立地是任选取代的C 6 -C 20脂族酰基; R 4是羟基,保护的羟基或-OP(O)(OH)2,其中R 1和R 4中的至少一个是-OP(O)(OH)2; R5是羟基,被保护的羟基或氟; 条件是除了R 1和R 5中的至少一个是氟以外,R 2和R 3中的至少一个是取代的C 6 -C 20脂族酰基,其具有(ⅰ)至少一个卤素取代基和(ⅱ)至少一个选自 由卤素,羟基和C 6 -C 20脂族酰氧基或R 2和R 3中的至少一个组成的基团是被至少一个卤素取代的C 6 -C 20脂族羧酸酰氧基取代的取代的C 6 -C 20脂族酰基; 具有脂质A样活性,并且可用于治疗,预防,诊断和支持由于免疫系统或肿瘤缺陷引起的疾病或病症的动物。 它们可以通过磷酸化相应的缺乏磷酰基的化合物来制备。