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    • 72. 发明授权
    • Dynamically variable separation among nanoparticles for nano-enhanced Raman spectroscopy (NERS) molecular sensing
    • 用于纳米增强拉曼光谱(NERS)分子感测的纳米颗粒之间的动态变化分离
    • US07342656B2
    • 2008-03-11
    • US11252134
    • 2005-10-17
    • M. Saif IslamShih-Yuan WangR. Stanley WilliamsPhilip J. KuekesWei WuZhiyong Li
    • M. Saif IslamShih-Yuan WangR. Stanley WilliamsPhilip J. KuekesWei WuZhiyong Li
    • G01J3/44G01N21/65
    • G01N21/658
    • A NERS-active structure includes a deformable, active nanoparticle support structure for supporting a first nanoparticle and a second nanoparticle that is disposed proximate the first nanoparticle. The nanoparticles each comprise a NERS-active material. The deformable, active nanoparticle support structure is configured to vary the distance between the first nanoparticle and the second nanoparticle while performing NERS. Various active nanoparticle support structures are disclosed. A NERS system includes such a NERS-active structure, a radiation source for generating radiation scatterable by an analyte located proximate the NERS-active structure, and a radiation detector for detecting Raman scattered radiation scattered by the analyte. A method for performing NERS includes providing such a NERS-active structure, providing an analyte at a location proximate the NERS-active structure, irradiating the NERS-active structure and the analyte with radiation, varying the distance between the nanoparticles, and detecting Raman scattered radiation scattered by the analyte.
    • NERS活性结构包括用于支撑第一纳米颗粒的可变形的活性纳米颗粒支撑结构和邻近第一纳米颗粒设置的第二纳米颗粒。 纳米颗粒各自包含NERS-活性材料。 可变形的活性纳米颗粒支撑结构被配置为在执行NERS的同时改变第一纳米颗粒和第二纳米颗粒之间的距离。 公开了各种活性纳米颗粒载体结构。 NERS系统包括这样的NERS-活性结构,用于产生由位于NERS-活性结构附近的分析物可散射的辐射的辐射源,以及用于检测被分析物散射的拉曼散射辐射的辐射检测器。 执行NERS的方法包括提供这样的NERS活性结构,在靠近NERS-活性结构的位置提供分析物,用辐射照射NERS-活性结构和分析物,改变纳米颗粒之间的距离并检测拉曼散射 被分析物散射的辐射。
    • 76. 发明申请
    • Dynamic random separation among nanoparticles for nano enhanced Raman spectroscopy (NERS) molecular sensing
    • 用于纳米增强拉曼光谱(NERS)分子感测的纳米颗粒之间的动态随机分离
    • US20070086002A1
    • 2007-04-19
    • US11252146
    • 2005-10-17
    • M. IslamShih-Yuan WangR. Williams
    • M. IslamShih-Yuan WangR. Williams
    • G01J3/44G01N21/65
    • G01N21/658Y10S977/786
    • A system for performing nanostructure-enhanced Raman spectroscopy (NERS) includes a radiation source, a radiation detector configured to detect Raman scattered radiation scattered by an analyte, and a container configured to provide a sealed enclosure. The NERS system further includes a turbulence generating device configured to generate random dynamic motion of a plurality of nanoparticles within the container. A method for performing NERS includes providing a container configured to provide a sealed enclosure, providing a plurality of nanoparticles each comprising a NERS-active material and an analyte within the container, causing random dynamic motion of the plurality of nanoparticles and the analyte, irradiating the plurality of nanoparticles and the analyte with radiation, and detecting Raman scattered radiation scattered by the analyte.
    • 用于执行纳米结构增强拉曼光谱(NERS)的系统包括辐射源,被配置为检测被分析物散射的拉曼散射辐射的辐射检测器和被配置为提供密封外壳的容器。 NERS系统还包括被配置成产生容器内的多个纳米颗粒的随机动态运动的湍流产生装置。 一种用于执行NERS的方法包括提供一种被配置成提供密封外壳的容器,提供多个纳米颗粒,每个纳米颗粒包含在容器内的NERS-活性材料和分析物,引起多个纳米颗粒和分析物的随机动态运动, 多个纳米颗粒和分析物与辐射,并检测被分析物散射的拉曼散射辐射。
    • 79. 发明申请
    • Method and apparatus for modifying an electromagnetic radiation beam
    • 用于修改电磁辐射束的方法和装置
    • US20070065068A1
    • 2007-03-22
    • US11230159
    • 2005-09-19
    • Shih-Yuan Wang
    • Shih-Yuan Wang
    • G02F1/295G02F1/01G02F1/035
    • G02F1/29B82Y20/00G02B1/007G02F2202/32
    • Devices and methods for modifying an electromagnetic beam include a tunable refractive medium, an input waveguide configured for directing an incident radiation to the tunable refractive medium, and at least one output waveguide configured for directing a focused radiation emanating from the tunable refractive medium. The tunable refractive medium comprises first electrodes coupled to a first surface of a periodic dielectric medium, and second electrodes coupled to a second surface of the periodic dielectric medium. The periodic dielectric medium includes a dielectric periodicity configured for providing a negative refraction of the incident radiation and focusing the focused radiation at a focal location. The focal location may be modified by at least one electromagnetic signal applied between the first electrodes and the second electrodes.
    • 用于修改电磁波束的装置和方法包括可调谐折射介质,被配置用于将入射辐射引导到可调谐折射介质的输入波导以及被配置为引导从可调谐折射介质发射的聚焦辐射的至少一个输出波导。 可调谐折射介质包括耦合到周期性电介质的第一表面的第一电极和耦合到周期性电介质的第二表面的第二电极。 周期性介电介质包括介质周期性,其配置用于提供入射辐射的负折射并将聚焦辐射聚焦在焦点位置。 可以通过施加在第一电极和第二电极之间的至少一个电磁信号来修改焦点位置。