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71. 发明申请

US20090069624A1 STABILIZER AND METHOD FOR IRRADIATING TUMORS 失效
标题翻译：稳定剂和辐射肿瘤的方法
公开(公告)号：US20090069624A1
公开(公告)日：2009-03-12
申请号：US12208224
申请日：2008-09-10
申请人： Robert Rioux
发明人： Robert Rioux
IPC分类号： A61N5/10 , A61B18/18
CPC分类号： A61B18/1477 , A61B2018/0016 , A61B2018/00577 , A61B2018/143 , A61B2018/1432 , A61B2018/1475 , A61N5/10
摘要： A method of treating a region of diseased tissue using a probe is disclosed. A probe cannula is introduced into the tissue of the patient until a distal end of the cannula is located at or proximate to the treatment region. A plurality of electrodes are then deployed from the distal end of the cannula into the treatment region. Energy (e.g., radiofrequency energy) is then delivered through the plurality of electrodes to the tissue. The cannula is then secured to an immobile object external to the patient. The treatment region is irradiated with a therapeutically effective dose of an ionizing radiation while the plurality of electrodes remain at least partially advanced within the treatment region and while the cannula remains secured to the immobile object.
摘要翻译：公开了一种使用探针治疗患病组织区域的方法。探针套管被引入到患者的组织中，直到套管的远端位于或接近治疗区域。然后，多个电极从插管的远端部署到治疗区域中。能量（例如，射频能量）然后通过多个电极传送到组织。然后将套管固定到患者外部的不可移动的物体。用治疗有效剂量的电离辐射照射治疗区域，同时多个电极在处理区域内保持至少部分地前进，并且套管保持固定在不动的物体上。

72. 发明申请

US20080319413A1 PERCUTANEOUS ARRAY DELIVERY SYSTEM 失效
标题翻译： PERCUTANEOUS ARRAY交付系统
公开(公告)号：US20080319413A1
公开(公告)日：2008-12-25
申请号：US12198818
申请日：2008-08-26
申请人： Robert Rioux , Jeffrey Bean
发明人： Robert Rioux , Jeffrey Bean
IPC分类号： A61M5/315
CPC分类号： A61M37/0069 , A61N5/1027 , A61N2005/1011 , A61N2005/1021
摘要： A system for treating tissue includes a cannula having a proximal end, a distal end, and a lumen extending between the proximal and the distal ends, and an array of delivery tubes at least partially disposed within the lumen, each of the delivery tube having a lumen, wherein each of the delivery tubes is slidable relative to the cannula, and has a first configuration when inside the lumen, and a second configuration when outside the lumen. A system for treating tissue includes a treatment device having a distal end, and an indexing device for controlling a longitudinal position of the distal end of the treatment device relative to a target tissue region, the indexing device having a tubular portion for receiving the treatment device.
摘要翻译：用于治疗组织的系统包括具有近端，远端和在近端和远端之间延伸的内腔的套管，以及至少部分地设置在内腔内的排出管阵列，每个输送管具有其中每个输送管相对于插管可滑动，并且当在内腔内时具有第一构型，以及当在内腔外时具有第二构造。一种用于治疗组织的系统包括具有远端的治疗装置和用于控制治疗装置的远端相对于靶组织区域的纵向位置的分度装置，分度装置具有用于接收治疗装置的管状部分。

73. 发明申请

US20070250053A1 ABLATION PROBE WITH RIBBED INSULATED SHEATH 有权
标题翻译：具有绝缘绝缘的吸引探头
公开(公告)号：US20070250053A1
公开(公告)日：2007-10-25
申请号：US11379537
申请日：2006-04-20
申请人： Kathleen Fernald , Robert Rioux
发明人： Kathleen Fernald , Robert Rioux
IPC分类号： A61B18/14
CPC分类号： A61B18/1482 , A61B18/1477 , A61B2017/00845 , A61B2018/00083 , A61B2018/00166 , A61B2018/00577 , A61B2018/1425
摘要： A tissue ablation probe comprises an electrically conductive probe shaft, at least one electrode, and an electrically insulative sheath disposed on the probe shaft. The insulative sheath has thickened regions forming alternating ribs and depressions that longitudinally extend along the probe shaft. The ribs allow the ablation probe to be delivered through a tightly toleranced delivery device. While the ribs may shear off during the delivery process, the underlying probe shaft will remain covered by the remaining portion of the insulative sheath. The tissue ablation probe may be used in a tissue ablation assembly that additionally comprises a delivery cannula having a lumen in which the tissue ablation probe may be removably disposed. In this case, the sheath has an outer periphery having a size substantially the same as the diameter of the lumen, so that the inner surface of the delivery cannula cooperates with the depressions to create lumens that longitudinally extend within the cannula.
摘要翻译：组织消融探针包括设置在探针轴上的导电探针轴，至少一个电极和电绝缘护套。绝缘护套具有加厚的区域，形成沿着探针轴纵向延伸的交替的肋和凹陷。这些肋允许消融探针通过紧密公差的输送装置输送。虽然肋可以在输送过程中剪切，但下面的探针轴将保持被绝缘护套的剩余部分覆盖。组织消融探针可以用在组织消融组件中，该组织消融组件另外包括具有内腔的输送套管，组织消融探针可以可移除地设置在该内腔中。在这种情况下，护套具有外径，其尺寸基本上与内腔的直径相同，使得输送套管的内表面与凹陷配合，以产生在插管内纵向延伸的流明。

74. 发明申请

US20070156127A1 FOAM ELECTRODE AND METHOD OF USE THEREOF DURING TISSUE RESECTION 有权
标题翻译：泡沫电极及其在组织检查中的使用方法
公开(公告)号：US20070156127A1
公开(公告)日：2007-07-05
申请号：US11611729
申请日：2006-12-15
申请人： Robert Rioux , Paul DiCarlo , Arnold Oyola
发明人： Robert Rioux , Paul DiCarlo , Arnold Oyola
IPC分类号： A61B18/14
CPC分类号： A61B18/1402 , A61B2018/00065 , A61B2018/00404 , A61B2018/00589 , A61B2018/00601 , A61B2018/00607 , A61B2018/1472
摘要： Assemblies and methods are provided for resecting a portion of tissue to be removed (e.g., unhealthy tissue, such as cancerous tissue) from a portion of the tissue to be retained (e.g., healthy tissue) within a patient is provided. An electrically conductive fluid, such as saline, may be absorbed into a hydrophilic electrode. Electrical energy (e.g., radio frequency (RF) energy) is conveyed to or from the hydrophilic electrode while being moved in proximity to the tissue along a resection line, whereby tissue adjacent to the resection line is coagulated. A resection member, such as a blunt resection member or a resection electrode, which may be on the same device as the hydrophilic electrode, is used to separate the tissue along the resection line to resect the tissue portion to be removed from the tissue portion to be retained.
摘要翻译：提供了组件和方法，用于从患者内要保留的组织的一部分（例如，健康组织）切除要去除的组织的一部分（例如，不健康的组织，例如癌组织）。诸如盐水的导电流体可以被吸收到亲水电极中。电能（例如射频（RF）能量）被输送到亲水电极或从亲水电极移动，同时沿着切除线移动到组织附近，由此与切除线相邻的组织凝固。使用可以与亲水电极在同一装置上的切除部件，例如钝器切除部件或切除电极，沿着切除线分离组织以将要从组织部分移除的组织部分切除到保留。

75. 发明申请

US20070142770A1 Echogenic occlusive balloon and delivery system 有权
标题翻译：回声气囊和输送系统
公开(公告)号：US20070142770A1
公开(公告)日：2007-06-21
申请号：US11316501
申请日：2005-12-21
申请人： Robert Rioux , David Sauvageau
发明人： Robert Rioux , David Sauvageau
IPC分类号： A61M31/00 , A61M37/00
CPC分类号： A61B8/12 , A61B90/39 , A61B2090/3925 , A61M25/10 , A61M37/00 , A61M2025/1052 , A61M2025/1079
摘要： A vessel occlusion apparatus includes an elongate shaft having a fluid delivery lumen; and an expandable member carried on a distal end portion of the shaft, the expandable member comprising a body defining an interior region, the interior region in communication with the fluid delivery lumen, the body comprising a wall having one or more embedded fluid pockets therein, each of the one or more pockets containing a fluid capable of being imaged, e.g., having echogenic qualities for detection using ultrasound imaging.
摘要翻译：容器闭塞装置包括具有流体输送腔的细长轴; 以及承载在所述轴的远端部分上的可扩张构件，所述可膨胀构件包括限定内部区域的主体，所述内部区域与所述流体输送腔连通，所述主体包括其中具有一个或多个嵌入式流体袋的壁，所述一个或多个口袋中的每一个包含能够成像的流体，例如具有用于使用超声成像检测的回波质量。

76. 发明申请

US20070021743A1 Compressible/expandable hydrophilic ablation electrode 审中-公开
标题翻译：可压缩/可膨胀的亲水性消融电极
公开(公告)号：US20070021743A1
公开(公告)日：2007-01-25
申请号：US11187246
申请日：2005-07-22
申请人： Robert Rioux , Paul DiCarlo
发明人： Robert Rioux , Paul DiCarlo
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B18/1492 , A61B2018/00214 , A61B2018/00577 , A61B2018/1472 , A61B2218/002
摘要： Methods, probe assemblies and systems are provided for treating tissue a margins surrounding interstitial spaces created via the removal of tumors. The interstitial space may be in any tissue, e.g., breast tissue, and the interstitial space may be created by removing abnormal tissue. A hydrophilic electrode is compressed and introduced (e.g., percutaneously) into the interstitial cavity. An electrically conductive liquid (e.g., saline) is applied to the electrode, such that the electrode absorbs the electrically conductive liquid. The electrode is expanded into contact with the tissue margin, and electrical energy (e.g., radio frequency (RF) energy) is conveyed to the electrode, thereby ablating the tissue margin.
摘要翻译：提供了方法，探针组件和系统用于处理通过去除肿瘤产生的间质空间周围的边缘的组织。间质空间可以在任何组织，例如乳房组织中，并且间隙空间可以通过去除异常组织来产生。将亲水电极压缩并引入（例如经皮）到间质腔中。将导电液体（例如盐水）施加到电极，使得电极吸收导电液体。电极膨胀成与组织边缘接触，电能（例如，射频（RF）能量）被传送到电极，从而消融组织边缘。

77. 发明授权

US07087051B2 Articulating radio frequency probe handle 有权
标题翻译：铰接射频探头手柄
公开(公告)号：US07087051B2
公开(公告)日：2006-08-08
申请号：US10345669
申请日：2003-01-15
申请人： George Bourne , Robert Rioux
发明人： George Bourne , Robert Rioux
IPC分类号： A61B18/18
CPC分类号： A61B18/148 , A61B18/1477 , A61B2018/1425 , A61B2018/143 , A61B2090/374 , A61B2090/376
摘要： A medical probe assembly and method for ablating tissue using radio frequency energy. The medical probe assembly includes an elongated shaft, a needle electrode array, and a hinged handle. The handle has a collar, which when in the up position covers the hinge so that the device can be used as a conventional medical probe. When the collar is in the down position the hinge is exposed, and the handle can be bent to reduce its overall height. With this reduced height the probe can be used while a patient is lying in a CT scanner or an MRI chamber. Therefore, the surgeon can monitor the ablation during the procedure, and thus avoid unnecessary damage to the surrounding healthy tissue on the one hand, and insufficient ablation of the diseased tissue on the other hand. An alternate embodiment uses a flexible handle instead of a hinged one.
摘要翻译：一种用于使用射频能量消融组织的医疗探针组件和方法。医疗探针组件包括细长轴，针电极阵列和铰接手柄。手柄具有一个套环，当其向上位置覆盖铰链时，该装置可用作传统的医用探针。当衣领处于向下位置时，铰链被暴露，并且手柄可以弯曲以减小其整体高度。随着这种降低的高度，当患者躺在CT扫描仪或MRI室中时，可以使用探头。因此，外科医生可以在手术过程中监测消融，因此避免了一方面对周围健康组织的不必要的损伤，另一方面避免了患病组织的消融不足。替代实施例使用柔性手柄而不是铰接的手柄。

78. 发明申请

US20060025764A1 Systems and methods for performing simultaneous ablation 有权
公开(公告)号：US20060025764A1
公开(公告)日：2006-02-02
申请号：US11238403
申请日：2005-09-28
申请人： Robert Rioux , Robert Garabedian , Jerry Jarrard
发明人： Robert Rioux , Robert Garabedian , Jerry Jarrard
IPC分类号： A61B18/14
CPC分类号： A61B18/148 , A61B18/1206 , A61B2018/00702 , A61B2018/00875 , A61B2018/143 , A61B2018/1475
摘要： A system for treating tissue includes first and second ablation devices each including a plurality of wire electrodes and coupled to a generator in parallel. In one embodiment, the generator includes first and second terminals coupled in parallel to one another, and the first and second ablation devices are connected to the first and second terminals, respectively. Alternatively, the first and second ablation devices are coupled to a single terminal of the generator using a “Y” cable. A ground electrode is coupled to the generator opposite the first and second ablation devices for monopolar operation. The first and second arrays of electrodes are inserted into first and second sites adjacent one another within a tissue region. Energy is simultaneously delivered to the first and second arrays to generate lesions at the first and second sites preferably such that the first and second lesions overlap.

79. 发明申请

US20060015132A1 Probe introducer with valve assembly to minimize air entry 审中-公开
标题翻译：带阀门组件的探头引导器，以最大限度地减少空气进入
公开(公告)号：US20060015132A1
公开(公告)日：2006-01-19
申请号：US10892866
申请日：2004-07-16
申请人： Robert Rioux , Kristian Dimatteo
发明人： Robert Rioux , Kristian Dimatteo
IPC分类号： A61M29/00
CPC分类号： A61B17/3462 , A61B17/3498 , A61B18/148 , A61M39/0606
摘要： A medical probe introducer includes a cannula having an axial lumen, and a valve assembly connected to the cannula. The valve assembly is configured to allow passage of a medical probe (e.g., a stylet probe, a biopsy probe, or a RF ablation probe), while substantially preventing the passage of air, through the cannula lumen.
摘要翻译：医疗探针引导器包括具有轴向内腔的插管和连接到套管的阀组件。阀组件构造成允许医疗探针（例如，探针，活检探针或RF消融探针）通过，同时基本上防止空气通过套管内腔。

80. 发明申请

US20060015098A1 Apparatus and methods for assisting ablation of tissue using magnetic beads 有权
标题翻译：使用磁珠辅助组织消融的装置和方法
公开(公告)号：US20060015098A1
公开(公告)日：2006-01-19
申请号：US11224864
申请日：2005-09-12
申请人： Robert Rioux , Robert Garabedian
发明人： Robert Rioux , Robert Garabedian
IPC分类号： A61B18/14 , A61F7/00 , A61F7/12
CPC分类号： A61N1/406 , A61N2/02
摘要： A system for treating tissue includes a source of conductive and/or magnetic beads, a first member, e.g., a catheter or cannula, coupled to the source of magnetic beads, and a second member, e.g., a catheter or cannula, carrying a magnet on its distal end. The system is used for ablating or otherwise treating tissue within a target tissue region including a blood vessel contacting or passing therethrough. Magnetic beads are introduced into the target tissue region, e.g., using the first member, and a magnetic field is generated within the target tissue region, e.g., using the second member, to cause the magnetic beads to migrate towards a wall of the vessel. Energy is delivered into the target tissue region, e.g., to heat tissue therein, and the magnetic beads may attenuate or enhance treatment of tissue adjacent to the vessel.
摘要翻译：用于治疗组织的系统包括导电和/或磁珠的源，耦合到磁珠源的第一构件，例如导管或插管，以及携带磁体的第二构件，例如导管或套管在其远端。该系统用于烧蚀或以其他方式处理包括接触或穿过其中的血管的靶组织区域内的组织。将磁珠引入目标组织区域，例如使用第一构件，并且例如使用第二构件在目标组织区域内产生磁场，使磁珠朝向容器的壁迁移。能量被递送到目标组织区域中，例如以加热其中的组织，并且磁珠可以减弱或增强对与血管相邻的组织的治疗。

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