专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

71. 发明专利

PA8611501A1 FORMAS DE DOSIFICACION DE AZITROMICINA CON EFECTOS SECUNDARIOS REDUCIDOS 未知
公开(公告)号：PA8611501A1
公开(公告)日：2005-08-04
申请号：PA8611501
申请日：2004-09-08
申请人： PFIZER PROD INC
发明人： APPEL LEAH ELIZABETH , THOMBRE AVINASH GOVIND , FRIESEN DWAYNE THOMAS , HERBIG SCOTT MAX , CREW MARSHALL DAVID , HAGEN TOMOTHY ARTHUR , LO JULIAN BELKNAP
IPC分类号： C07H17/00 , A61K9/00 , A61K9/16 , A61K9/20 , A61K31/7052 , A61K47/02 , A61K47/14 , A61K47/18 , A61K47/44 , A61P31/04 , C07G11/00
摘要： UNA FORMA DE DOSIFICACION ORAL QUE COMPRENDE AZITROMICINA Y UNA CANTIDAD EFICAZ DE UN AGENTE ALCALINIZANTE. PREFERIBLEMENTE, DICHA FORMA DE DOSIFICACION ORAL COMPRENDE UNA CANTIDAD EFICAZ DE UN AGENTE ALCALINIZANTE Y UN MULTIPARTICULADO DE AZITROMICINA EN EL QUE DICHO MULTIPARTICULADO COMPRENDE AZITROMICINA, UNA MEZCLA DE MONOBEHENATO DE GLICERILO, DIBEHENATO DE GLICERILO Y TRIBEHENATO DE GLICERILO Y UN POLOXAMERO. TIPICAMENTE, LA FORMA DE DOSIFICACION ORAL INCLUYE CUALQUIER MEDIO DE ADMINISTRACION ORAL ADECUADO TAL COMO UN POLVO PARA SUSPENSION ORAL, UN ENVASE O SOBRECITO DE DOSIS UNITARIA, UN COMPRIMIDO O UNA CAPSULA. ADEMAS SE DESCRIBE UNA SUSPENSION ORAL QUE COMPRENDE AZITROMICINA, UNA CANTIDAD EFICAZ DE UN AGENTE ALCALINIZANTE Y UN VEHICULO. PREFERIBLEMENTE, LA AZITROMICINA ESTA EN FORMA MULTIPARTICULADA EN LA QUE DICHO MULTIPARTICULADO COMPRENDE AZITROMICINA, UNA MEZCLA DE MONOBEHENATO DE GLICERILO, DIBEHENATO DE GLICERILO Y TRIBEHENATO DE GLICERILO Y UN POLOXAMERO. TAMBIEN SE DESCRIBE UN PROCEDIMIENTO PARA REDUCIR LOS EFECTOS SECUNDARIOS GASTROINTESTINALES ASOCIADOS A LA ADMINISTRACION DE AZITROMICINA A UN MAMIFERO, QUE COMPRENDE LA ADMINISTRACION DE FORMA CONTIGUA DE AZITROMICINA Y UNA CANTIDAD EFICAZ DE UN AGENTE ALCALINIZANTE A DICHO MAMIFERO EN EL QUE LA FRECUENCIA DE EFECTOS SECUNDARIOS GASTROINTESTINALES ES MENOR QUE LA QUE SE EXPERIMENTA ADMINISTRANDO UNA DOSIS IGUAL DE AZITROMICINA SIN DICHO AGENTE ALCALINIZANTE. ADEMAS SE DESCRIBE UN PROCEDIMIENTO PARA TRATAR UNA INFECCION BACTERIANA O PROTOZOARIA EN UN MAMIFERO QUE LO NECESITE QUE COMPRENDE LA ADMINISTRACION DE FORMA CONTIGUA A DICHO MAMIFERO DE UNA DOSIS UNICA DE UNA FORMA DE DOSIFICACION ORAL EN LA QUE DICHA FORMA DE DOSIFICACION ORAL COMPRENDE AZITROMICINA Y UNA CANTIDAD EFICAZ DE UN AGENTE ALCALINIZANTE. ADICIONALMENTE SE DESCRIBEN MULTIPARTICULADOS DE AZITROMICINA QUE COMPRENDEN AZITROMICINA, UN TENSIOACTIVO; Y UN VEHICULO FARMACEUTICAMENTE ACEPTABLE.

73. 发明专利

MXPA05000976A FORMULACIONES DE LIBERACION CONTROLADA CON SABOR AGRADABLE PARA ANIMALES DE COMPANIA. 未知
公开(公告)号：MXPA05000976A
公开(公告)日：2005-05-16
申请号：MXPA05000976
申请日：2003-07-28
申请人： PFIZER PROD INC
发明人： THOMBRE AVINASH GOVIND
IPC分类号： A61K9/56 , A23K1/00 , A23K1/18 , A61K9/00 , A61K9/20 , A61K9/22 , A61K31/403 , A61K47/32 , A61K47/34 , A61K47/38 , A61K47/46 , B01J23/85 , B01J23/883 , B01J27/19 , B01J35/00 , B01J35/10 , C10G45/04 , C10G45/06 , C10G65/04 , A61K9/16 , A61K9/50
摘要： La invencion se refiere a composiciones farmaceuticas multiparticula de liberacion controlada y masticables para animales de compania y un procedimiento para la preparacion de las mismas.

74. 发明专利

BR0312410A 未知
公开(公告)号：BR0312410A
公开(公告)日：2005-04-26
申请号：BR0312410
申请日：2003-06-26
申请人： PFIZER PROD INC
发明人： BERCHIELLI ALFRED , DAUGHERITY PATRICK DAVID , SHAMBLIN SHERI LYNN , THOMBRE AVINASH GOVIND , WATERMAN KENNETH CRAIG
IPC分类号： A61K9/00 , A61K9/22 , A61K31/4433

75. 发明专利

NZ518281A Controlled release drug dosage core comprising a drug-containing composition and a water-swellable composition 未知
公开(公告)号：NZ518281A
公开(公告)日：2005-01-28
申请号：NZ51828100
申请日：2000-12-20
申请人： PFIZER PROD INC
发明人： APPEL LEAH ELIZABETH , BEYERINCK RONALD ARTHUR , CHIDLAW MARK BRIAN , CURATOLO WILLIAM JOHN , FRIESEN DWAYNE THOMAS , SMITH KELLY LINCOLN , THOMBRE AVINASH GOVIND
IPC分类号： A61K9/22 , A61K9/00 , A61K9/28 , A61K9/36 , A61K47/36 , A61K47/38
摘要： A controlled release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The drug-containing composition comprises a low-solubility drug and a drug-entraining agent. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of formulations having specific drug release profiles are disclosed.

77. 发明专利

NO20043903L 未知
公开(公告)号：NO20043903L
公开(公告)日：2004-11-09
申请号：NO20043903
申请日：2004-09-17
申请人： PFIZER PROD INC
发明人： MCCRAY SCOTT BALDWIN , LYON DAVID KEITH , WEST JAMES BLAIR , THOMBRE AVINASH GOVIND , HERBIG SCOTT MAX , APPEL LEAH ELIZABETH , CREW MARSHALL DAVID , FRIESEN DWAYNE THOMAS , HAGEN TIMOTY ARTHUR , LO JULIAN BELKNAP
IPC分类号： C07H17/00 , A61K9/00 , A61K9/16 , A61K9/20 , A61K31/7052 , A61K47/02 , A61K47/14 , A61K47/18 , A61K47/44 , A61P31/04
摘要： An oral dosage form comprising azithromycin and an effective amount of an alkalizing agent. Preferably, said oral dosage form comprises an effective amount of an alkalizing agent and an azithromycin multiparticulate wherein said multiparticulate comprises azithromycin, a mixture of glyceryl monobehenate, glyceryl dibehenate and glyceryl tribehenate, and a poloxamer. Typically, the oral dosage form includes any suitable oral dosing means such as a powder for oral suspension, a unit dose packet or sachet, a tablet or a capsule. Additionally disclosed is an oral suspension comprising azithromycin, an effective amount of an alkalizing agent and a vehicle. Preferably, the azithromycin is in multiparticulate form wherein said multiparticulate comprises azithromycin, a mixture of glyceryl monobehenate, glyceryl dibehenate and glyceryl tribehenate, and a poloxamer. Also disclosed is a method for reducing gastrointestinal side effects, associated with administering azithromycin to a mammal, comprising contiguously administering azithromycin and an effective amount of alkalizing agent to said mammal wherein the frequency of gastrointestinal side effects is lower than that experienced by administering an equal dose of azithromycin without said alkalizing agent. Further disclosed is a method of treating a bacterial or protozoal infection in a mammal in need thereof comprising contiguously administering to said mammal a single dose of an oral dosage form wherein said oral dosage form comprises azithromycin and an effective amount of an alkalizing agent. Additionally disclosed are azithromycin multiparticulates comprising azithromycin, a surfactant; and a pharmaceutically acceptable carrier.

78. 发明专利

NO20043903A 未知
公开(公告)号：NO20043903A
公开(公告)日：2004-11-09
申请号：NO20043903
申请日：2004-09-17
申请人： PFIZER PROD INC
发明人： MCCRAY SCOTT BALDWIN , LYON DAVID KEITH , WEST JAMES BLAIR , THOMBRE AVINASH GOVIND , HERBIG SCOTT MAX , APPEL LEAH ELIZABETH , CREW MARSHALL DAVID , FRIESEN DWAYNE THOMAS , HAGEN TIMOTY ARTHUR , LO JULIAN BELKNAP
IPC分类号： C07H17/00 , A61K9/00 , A61K9/16 , A61K9/20 , A61K31/7052 , A61K47/02 , A61K47/14 , A61K47/18 , A61K47/44 , A61P31/04
CPC分类号： A61K9/1611 , A61K9/143 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1641 , A61K9/1694 , A61K9/2009 , A61K9/2013 , A61K9/2031 , A61K31/7052

79. 发明专利

PL357535A1 HYDROGEL-DRIVEN DRUG DOSAGE FORM 未知
公开(公告)号：PL357535A1
公开(公告)日：2004-07-26
申请号：PL35753500
申请日：2000-12-20
申请人： PFIZER PROD INC
发明人： APPEL LEAH ELIZABETH , BEYERINCK RONALD ARTHUR , CHIDLAW MARK BRIAN , CURATOLO WILLIAM JOHN , FRIESEN DWAYNE THOMAS , SMITH KELLY LINCOLN , THOMBRE AVINASH GOVIND
IPC分类号： A61K9/22 , A61K9/00 , A61K9/28 , A61K9/36 , A61K47/36 , A61K47/38
摘要： A controlled -release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The drug-containing composition comprises a low-solubility drug and a drug-entraining agent. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of formulations having specific drug release profiles are disclosed.

80. 发明专利

CA2493435A1 PHARMACEUTICAL LASER DRILLING SYSTEM WITH MEANS FOR CHECKINGTHE CORRECT ORIENTATION OF EACH DOSAGE 未知
公开(公告)号：CA2493435A1
公开(公告)日：2004-01-29
申请号：CA2493435
申请日：2003-07-11
申请人： PFIZER PROD INC
发明人： SPENCE KENNY RAY , NEWBOLD DAVID DIXON , MILLARD DOUGLAS LEE , CRAIG CHRISTOPHER DONAVAN , CARRUTHERS MARK SAMUEL , THOMBRE AVINASH GOVIND
IPC分类号： A61J3/06 , A61J3/00 , B23K26/04 , B23K26/08 , B23K26/14 , B23K26/38 , B23K26/42 , A61K9/00 , A61K9/20 , B07C5/342 , B07C5/36 , B65G47/256
摘要： A laser drilling system (10) forms an opening in the coating of a pharmaceutical dosage form and includes an orientation check assembly to che ck the correct orientation of each dosage form before the laser drilling is performed, a debris removal assembly to reduce buildup of and reduce exposur e to drilling debris and a quality control assembly to verify that the opening formed conforms to predetermined specifications. The orientation check assembly comprises first and second link conveyors, one first color sensor (52) located adjacent the first link conveyor and generating a signal representative of the color of the pharmaceutical dosage form, and a rejecti on station located along said first link conveyor for ejecting said dosage form in response to said signal generated by said color sensor (52).

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式