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    • 76. 发明申请
    • GAME MACHINE AND COMPUTER PROGRAM THEREOF
    • 游戏机及其计算机程序
    • US20100113132A1
    • 2010-05-06
    • US12531477
    • 2008-02-29
    • Yosuke SasakiShinichi IshiiMakoto AndoYaku HiranabeTomoaki HiraiEmiko Miyaji
    • Yosuke SasakiShinichi IshiiMakoto AndoYaku HiranabeTomoaki HiraiEmiko Miyaji
    • A63F9/24A63F13/00
    • G07F17/34G07F17/32G07F17/3244G07F17/3265G07F17/3267
    • A game machine having a control unit as a first game chance control device generating a game chance achieving at least one winning combination in winning combinations whose achievement probability varies in a game within a predetermined range provided to the player in exchange for medals, a dividend value control device setting a correspondence relationship between the winning combinations and the dividend values for the player, a dividend display control device displaying an odds display section where the winning combinations are related with the dividend values on a monitor according to the correspondence relationship set by the dividend value control device, a dividend creating device generating the dividend for the player corresponding to the achieved winning combination according to the correspondence relationship set by the dividend value control device when any winning combination is achieved, and a condition determining device determining whether a predetermined dividend change condition is established within the predetermined range.
    • 一种游戏机,其具有作为第一游戏机会控制装置的控制单元,其产生在提供给玩家的预定范围内的游戏中的成就概率变化的获胜组合中的至少一个获胜组合的游戏机会,以换取奖牌,股息值 控制装置设定所述获胜组合与所述玩家的所述分红值之间的对应关系,所述股息显示控制装置根据由所述股息设定的所述对应关系,在所述监视器上显示所述获胜组合与所述分红值相关联的赔率显示部 价值控制装置,分配生成装置,根据由所述股利价值控制装置实现的任何获胜组合时所设定的对应关系,根据所获得的获胜组合生成对应于玩家的股息;以及条件判定装置, 条件建立在预定范围内。
    • 79. 发明授权
    • N-substituted-2-oxodihydropyridine derivatives
    • N-取代-2-氧代二氢吡啶衍生物
    • US07138525B2
    • 2006-11-21
    • US10899162
    • 2004-07-27
    • Nagaaki SatoMakoto AndoShiho IshikawaTsuyoshi NagaseKeita NagaiAkio Kanatani
    • Nagaaki SatoMakoto AndoShiho IshikawaTsuyoshi NagaseKeita NagaiAkio Kanatani
    • C07D211/80
    • C07D213/80C07D401/04C07D401/14
    • A compound of the formula (I): (wherein Ar1 and Ar2 are independently aryl or heteroaryl, any of which is optionally substituted by a substituent selected from the group consisting of cyano, halogen, nitro, lower alkyl, halo-lower alkyl, hydroxy-lower alkyl, cyclo-lower alkyl, cyclo(lower alkyl)-lower alkyl, lower alkenyl, lower alkylamino, di-lower alkylamino, lower alkanoylamino, lower alkylsulfonylamino, arylsulfonylamino, hydroxy, lower alkoxy, halo-lower alkoxy, aryloxy, heteroaryloxy, lower alkylthio, carboxyl, formyl, lower alkanoyl, lower alkoxycarbonyl, carbamoyl, lower alkylcarbamoyl, di-lower alkylcarbamoyl, lower alkylsulfonyl, arylsulfonyl, aryl and heteroaryl; R1 and R2 are independently lower alkyl, cyclo-lower alkyl, cyclo(lower alkyl)-lower alkyl or lower alkoxy, any of which is optionally substituted by a substituent selected from the group consisting of halogen, lower alkylamino, di-lower alkylamino, lower alkanoylamino, hydroxy, lower alkoxy, formyl, lower alkoxycarbonyl, lower alkylcarbamoyl and di-lower alkylcarbamoyl; R3, R4 and R5 are independently hydrogen, cyano, halogen or hydroxy, or lower alkyl, lower alkoxy or lower alkylthio, the last three groups being optionally substituted by a substituent selected from the group consisting of halogen, lower alkylamino, di-lower alkylamino, lower alkanoylamino, hydroxy, lower alkoxy, formyl, lower alkoxycarbonyl, lower alkylcarbamoyl and di-lower alkylcarbamoyl), or a salt or ester thereof is useful as a neuropeptide Y receptor antagonist agent and is also useful as an agent for the treatment of bulimia, obesity or diabetes.
    • 式(I)的化合物:其中Ar 1和Ar 2独立地为芳基或杂芳基,其中任何一个任选被选自以下的取代基取代: 氰基,卤素,硝基,低级烷基,卤代低级烷基,羟基 - 低级烷基,环 - 低级烷基,环(低级烷基) - 低级烷基,低级烯基,低级烷基氨基,二低级烷基氨基,低级烷酰基氨基,低级烷基磺酰基氨基 ,芳基磺酰基氨基,羟基,低级烷氧基,卤代低级烷氧基,芳氧基,杂芳氧基,低级烷硫基,羧基,甲酰基,低级烷酰基,低级烷氧基羰基,氨基甲酰基,低级烷基氨基甲酰基,二低级烷基氨基甲酰基,低级烷基磺酰基,芳基磺酰基,芳基和杂芳基; R R 1和R 2独立地是低级烷基,环 - 低级烷基,环(低级烷基) - 低级烷基或低级烷氧基,其中任何一个任选被选定的取代基取代 由卤素,低级烷基氨基,二低级烷基氨基,低级烷酰氨基,低级烷基氨基, 低级烷氧基,甲酰基,低级烷氧基羰基,低级烷基氨基甲酰基和二低级烷基氨基甲酰基; R 3,R 4和R 5独立地是氢,氰基,卤素或羟基,或低级烷基,低级烷氧基或低级烷硫基, 最后三个基团任选被选自卤素,低级烷基氨基,二低级烷基氨基,低级烷酰基氨基,羟基,低级烷氧基,甲酰基,低级烷氧基羰基,低级烷基氨基甲酰基和二低级烷基氨基甲酰基的取代基取代)或盐 或其酯可用作神经肽Y受体拮抗剂,并且也可用作治疗贪食症,肥胖症或糖尿病的药剂。