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    • 71. 发明授权
    • Integrated polarization analyzer for fiber telecommunications
    • 光纤通信集成偏振分析仪
    • US06927845B2
    • 2005-08-09
    • US10288353
    • 2002-11-04
    • Jian Liu
    • Jian Liu
    • G01J4/04G01N21/21G01N21/00
    • G01N21/211G01J4/04
    • A method is disclosed in this invention for designing an optical polarization analyzer for measuring a state of polarization (SOP) of an optical signal transmitted over a particular range of wavelengths. The method includes a step of selecting a corner cube having a specific input medium refraction index and comprising four triangular surfaces and attaching four optical detectors on each of the four surfaces for sequentially absorbing and then reflecting an incident light from one detector to a next detector wherein said incident light is within the particular range of wavelengths. The method further includes a step of selecting a coating to coat over each of the detectors disposed on each of the four surfaces by selecting a coating material and designing an accurately controlled thickness of each of the coatings for controlling a absorption/reflectance ratio for each of the detectors whereby an optimal sensitivity of photopolarimeter is achieved.
    • 在本发明中公开了一种用于设计用于测量在特定波长范围上传输的光信号的偏振态(SOP)的光学偏振分析器的方法。 该方法包括选择具有特定输入介质折射率并包括四个三角形表面的角立方体的步骤,并且在四个表面中的每一个上附接四个光学检测器,以顺序吸收然后将来自一个检测器的入射光反射到下一个检测器,其中 所述入射光在特定的波长范围内。 该方法还包括通过选择涂层材料并设计每个涂层的精确控制的厚度来选择涂覆在布置在四个表面中的每一个上的每个检测器上的涂层以控制每个涂层的吸收/反射率的步骤 由此获得光偏振计的最佳灵敏度的检测器。
    • 73. 发明申请
    • High power pulse shaping fiber laser for high data rate free space telecommunication systems
    • 高功率脉冲整形光纤激光器,用于高数据速率自由空间电信系统
    • US20050036525A1
    • 2005-02-17
    • US10825746
    • 2004-04-15
    • Jian Liu
    • Jian Liu
    • G02B6/34H01S3/00H01S3/067H01S3/091H01S3/0941H01S3/10H01S3/16H01S3/30
    • H01S3/0941H01S3/005H01S3/0078H01S3/0085H01S3/06708H01S3/0675H01S3/06758H01S3/1608
    • An amplified laser source for amplifying a laser projection that includes a diode laser source modulated by a pulse generator applying an alternate high and low voltages higher and lower than a threshold voltage for projecting a modulated optical signal. The laser source further includes a first erbium-doped fiber (EDF) for amplifying the modulated optical signal. The laser source further includes a set of Bragg gratings for receiving the modulated optical signal from the first EDF for reflecting a grating-specific pulse-distortion-reduced optical signal. The laser source further includes an electro-absorption (EA) modulator synchronized with the pulse generator for increasing an extinction ratio of the optical signals. The laser source further includes a second erbium doped fiber (EDF) for receiving and amplifying the optical signal from the EA modulator wherein the second erbium doped fiber (EDF) having a length of several meters and a diameter greater than or equal to thirty-five micrometers.
    • 一种用于放大激光投射的放大激光源,其包括由脉冲发生器调制的二极管激光源,所述脉冲发生器施加高于和低于用于投影调制光信号的阈值电压的低和低的电压。 激光源还包括用于放大经调制的光信号的第一掺铒光纤(EDF)。 激光源还包括一组布拉格光栅,用于从第一EDF接收经调制的光信号,用于反射特定于光栅的脉冲失真减小的光信号。 激光源还包括与脉冲发生器同步的电吸收(EA)调制器,以增加光信号的消光比。 激光源还包括用于接收和放大来自EA调制器的光信号的第二掺铒光纤(EDF),其中第二掺铒光纤(EDF)的长度为几米,直径大于或等于三十五 微米。
    • 79. 发明授权
    • Method for solid phase synthesis of liraglutide
    • 利拉鲁肽固相合成方法
    • US09260474B2
    • 2016-02-16
    • US14344660
    • 2012-08-30
    • Junfeng PanJian LiuYaping MaJiancheng Yuan
    • Junfeng PanJian LiuYaping MaJiancheng Yuan
    • C07K1/20C07K14/575C07K1/04C07K1/107C07K1/06C07K14/605C07K1/14
    • C07K1/042C07K1/064C07K1/1077C07K1/14C07K14/605Y02P20/55
    • Provided is a method for solid phase synthesis of liraglutide, comprising the following steps: A), Fmoc-Gly-resin being obtained by coupling resin solid phase carrier with glycine with N-end protected by Fmoc(Fmoc-Gly-OH) in the presence of activator system; B) according to the peptide sequence of the main chain of liraglutide, successively coupling with amino acids with N-ends protected by Fmoc and protected side chains by the method for solid phase synthesis, wherein lysine employs Fmoc-Lys(Alloc)-OH; C) removing the protective group, Alloc, from the side chain of lysine; D) coupling the side chain of lysine with Palmitoyl-Glu-OtBu by the method for solid phase synthesis; E) cleavage, removing protection groups and resin to obtain crude liraglutide; F) purifying and lyophilizing to obtain liraglutide.
    • 本发明提供了利拉鲁肽的固相合成方法,其包括以下步骤:A),通过将树脂固相载体与由Fmoc(Fmoc-Gly-OH)保护的N-末端的甘氨酸偶联得到的Fmoc-Gly-树脂 活化剂体系的存在; B)根据利拉鲁肽主链的肽序列,通过固相合成方法依次与由Fmoc和被保护的侧链保护的N-末端的氨基酸偶联,其中赖氨酸使用Fmoc-Lys(Alloc)-OH; C)从赖氨酸侧链中除去保护基团,分配; D)通过固相合成方法将赖氨酸侧链与棕榈酰-Glu-OtBu偶联; E)裂解,去除保护基和树脂以获得粗利拉鲁肽; F)纯化和冻干以获得利拉鲁肽。
    • 80. 发明授权
    • Method and apparatus for high speed surface blackening and coloring with ultrafast fiber lasers
    • 用于高速表面黑化和超快速光纤激光着色的方法和装置
    • US09221269B2
    • 2015-12-29
    • US13973856
    • 2013-08-22
    • Jian Liu
    • Jian Liu
    • B82Y30/00B82Y40/00B23K26/00B41J2/435B41J2/32B41J2/44
    • B41J2/32B23K26/352B23K26/355B41J2/442B82Y30/00B82Y40/00
    • Methods and systems for high speed surface blackening and/or coloring are disclosed, including generating electromagnetic radiation from an ultrashort pulse laser (UPL); coupling the electromagnetic radiation from the UPL to a scanner comprising a scanning and focus range, wherein the scanner is configured to receive the electromagnetic radiation from the UPL and to scan and focus the electromagnetic radiation onto a sample; using a computer to adjust the pulse repetition rate and the energy of the UPL; using a five degree of freedom motorized stage to position the sample; using a dichroic filter positioned between the scanner and the sample; focusing an imager through the dichroic filter and onto the surface of the sample; using a processor to acquire and process images to monitor the surface blackening and/or coloring of the sample within the scanning and focus range of the electromagnetic radiation. Other embodiments are described and claimed.
    • 公开了用于高速表面黑化和/或着色的方法和系统,包括从超短脉冲激光(UPL)产生电磁辐射; 将来自UPL的电磁辐射耦合到包括扫描和聚焦范围的扫描器,其中扫描器被配置为从UPL接收电磁辐射并扫描并聚焦到样品上; 使用电脑调节UPL的脉冲重复率和能量; 使用五自由度机动化阶段来定位样品; 使用位于扫描仪和样品之间的二向色滤光片; 将成像器通过二向色滤光片聚焦到样品的表面上; 使用处理器来获取和处理图像以在电磁辐射的扫描和聚焦范围内监测样品的表面变黑和/或着色。 描述和要求保护其他实施例。