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71. 发明申请

US20110064189A1 Method and System for Needle Tracking in Fluoroscopic Image Sequences 有权
标题翻译：荧光图像序列中针跟踪的方法和系统
公开(公告)号：US20110064189A1
公开(公告)日：2011-03-17
申请号：US12880319
申请日：2010-09-13
申请人： Peng Wang , Marcus Pfister , Terrence Chen , Martin Ostermeier , Dorin Comaniciu
发明人： Peng Wang , Marcus Pfister , Terrence Chen , Martin Ostermeier , Dorin Comaniciu
IPC分类号： A61B6/02
CPC分类号： A61B6/12
摘要： A method and system for tracking a needle in a fluoroscopic image sequence is disclosed. In order to track a needle in a fluoroscopic image sequence, the needle is initialized in a first frame of the fluoroscopic image sequence. Needle segments are detected in each subsequent frame of the fluoroscopic image sequence, and the needle is detected in each frame of the fluoroscopic image by tracking the needle from a previous frame of the fluoroscopic image sequence based on the detected needle segments in the current frame.
摘要翻译：公开了一种用于在荧光镜像图像序列中跟踪针的方法和系统。为了在透视图像序列中跟踪针，在荧光镜图像序列的第一帧中初始化针。在透视图像序列的每个随后的帧中检测针段，并且基于当前帧中检测到的针段，通过从荧光透视图像序列的先前帧跟踪针来在荧光镜图像的每个帧中检测针。

72. 发明申请

US20100240970A1 METHOD FOR AN IN VIVO MEASUREMENT USING A DEVICE IMPLANTED IN A PATIENT, AND CORRESPONDING DEVICE 审中-公开
标题翻译：用于使用植入在患者中的装置进行体内测量的方法以及相关装置
公开(公告)号：US20100240970A1
公开(公告)日：2010-09-23
申请号：US12723940
申请日：2010-03-15
申请人： Arne HENGERER , Andreas Kappel , Luis Lasalvia , Andrea Lichte , Thomas Mertelmeier , Sven Meyburg , Christoph Petry , Marcus Pfister , Martin Requardt
发明人： Arne HENGERER , Andreas Kappel , Luis Lasalvia , Andrea Lichte , Thomas Mertelmeier , Sven Meyburg , Christoph Petry , Marcus Pfister , Martin Requardt
IPC分类号： A61B5/145 , A61M31/00
CPC分类号： A61B5/0002 , A61B5/14503 , A61B5/4839 , A61B10/0045
摘要： An embodiment of the present invention relates to a device, which can be implanted into a patient, for an in vivo measurement. In an embodiment, the device includes a catheter for guiding a sample of the patient town analysis unit in the device. A measurement result is determined in the analysis unit by analyzing the sample with the aid of a reagent. In an embodiment, the device furthermore includes an interchange chamber, with the aid of which the reagent can be removed from the device or can be inserted into the device. The interchange chamber has a connector allowing removal or insertion of the reagent while the device is implanted.
摘要翻译：本发明的一个实施例涉及可以植入患者体内的用于体内测量的装置。在一个实施例中，该装置包括用于引导装置中的患者镇分析单元的样本的导管。借助于试剂分析样品，在分析单元中测定结果。在一个实施方案中，该装置还包括一个互换室，借助于此可以将该试剂从该装置中移除或者可插入该装置中。交换室具有连接器，其允许在植入装置时移除或插入试剂。

73. 发明授权

US07706854B2 Device for recording cross-sectional images 有权
标题翻译：用于记录截面图像的装置
公开(公告)号：US07706854B2
公开(公告)日：2010-04-27
申请号：US11410631
申请日：2006-04-25
申请人： Martin Kleen , Marcus Pfister
发明人： Martin Kleen , Marcus Pfister
IPC分类号： A61B5/05
CPC分类号： A61B5/6852 , A61B5/0066 , A61B5/0073
摘要： In order to improve the quality of cross-sectional images, which have been recorded along a longitudinal axis of a vessel of a body, it is proposed to add successive cross-sectional images to an overall cross-sectional image. Artifacts in the cross-sectional images are hereby weakened and pathological structures to be detected are high-lighted.
摘要翻译：为了提高沿着身体的血管的纵轴记录的横截面图像的质量，建议将连续的横截面图像添加到整个横截面图像。因此，横截面图像中的人造物被削弱，并且待检测的病理结构被高光照射。

74. 发明申请

US20090274271A1 SYSTEM AND METHOD FOR SELECTING A GUIDANCE MODE FOR PERFORMING A PERCUTANEOUS PROCEDURE 有权
标题翻译：用于选择执行PERCUTANEOUS程序的指导模式的系统和方法
公开(公告)号：US20090274271A1
公开(公告)日：2009-11-05
申请号：US12431518
申请日：2009-04-28
申请人： Marcus Pfister , Norbert Strobel
发明人： Marcus Pfister , Norbert Strobel
IPC分类号： G01N23/04 , A61N5/10 , A61B6/08
CPC分类号： A61B6/12 , A61B6/4441 , A61B6/5229 , A61B90/11 , A61B90/13 , A61B2034/107 , A61B2090/364 , A61B2090/376 , A61N2005/1061 , G06F19/00
摘要： A system and method are disclosed for planning a percutaneous procedure and for guiding an instrument to engage a target within a patient's body. A patient 3-dimensional image data set is provided, within which a user defines an instrument trajectory, for example, by selecting a skin entry point and a target point. A line, or “planned path,” is generated between the points. The system determines whether the path can be targeted so the optical axis of the movable arm coincides with the path so that a laser can be used for instrument guidance. Alternatively, the user can determine whether planned path can be targeted so that the C-arm can be made to coincide with the path so that the extension of the path is projected onto the detector, using x-ray radiation. If neither laser guidance or x-ray guidance can be used, the physician is prompted to re-plan the path so that at least x-ray radiation guidance can be used. Once the desired guidance method is selected, the puncture instrument is guided along the planned path to engage the target.
摘要翻译：公开了一种用于规划经皮程序和引导器械使患者身体内的目标接合的系统和方法。提供了一种患者的三维图像数据集，其中用户通过选择皮肤入口点和目标点来定义仪器轨迹。点之间产生一行或“计划路径”。系统确定路径是否可以被定向，使可动臂的光轴与路径重合，使得激光可以用于仪器引导。或者，用户可以确定是否可以定向计划的路径，使得C臂可以与路径一致，使得使用x射线辐射将路径的延伸投影到检测器上。如果既不能使用激光引导或X射线引导，也可以提示医生重新规划路径，以至少可以使用x射线辐射引导。一旦选择了所需的引导方法，穿刺器械沿着规划的路径被引导以接合目标。

75. 发明申请

US20090198124A1 WORKFLOW TO ENHANCE A TRANSJUGULAR INTRAHEPATIC PORTOSYSTEMIC SHUNT PROCEDURE 审中-公开
标题翻译：加强输血内镜手术切除手术的工作流程
公开(公告)号：US20090198124A1
公开(公告)日：2009-08-06
申请号：US12023906
申请日：2008-01-31
申请人： Ralf Adamus , Marcus Pfister
发明人： Ralf Adamus , Marcus Pfister
IPC分类号： A61B6/00
CPC分类号： A61B6/12 , A61B5/055 , A61B6/02 , A61B6/4441 , A61B6/481 , A61B6/504
摘要： A method and appertaining system are provided for performing an image-assisted subject procedure. The method comprises obtaining at least a first and a second 2D projected image of a 3D subject from a first angle and a second angle. A user selects at least a first point and a second point in each of the first and second 2D images, and the system calculates 3D positions of the first point and the second point based on the selected points in the 3D images and the first and second angles. The, a 3D line is calculated between the first and second points. A further projected 2D image is created that includes the calculated 3D position of at least one of: a) one of the points; and b) the line. The subject procedure is then subsequently performed utilizing the further projected 2D image as a guide.
摘要翻译：提供了一种用于执行图像辅助对象程序的方法和附加系统。该方法包括从第一角度和第二角度获得3D对象的至少第一和第二2D投影图像。用户选择第一和第二2D图像中的每一个中的至少第一点和第二点，并且系统基于3D图像中的所选点计算第一点和第二点的3D位置，并且第一和第二2D 角度。在第一和第二点之间计算3D线。创建另外投影的2D图像，其包括以下中的至少一个的计算的3D位置：a）点之一; 和b）线。然后随后使用进一步投影的2D图像作为指导来执行主题程序。

76. 发明申请

US20090069672A1 Device localization and guidance 有权
标题翻译：设备本地化和指导
公开(公告)号：US20090069672A1
公开(公告)日：2009-03-12
申请号：US11900261
申请日：2007-09-11
申请人： Marcus Pfister , Laura Johnson
发明人： Marcus Pfister , Laura Johnson
IPC分类号： A61B8/00
CPC分类号： A61B6/12 , A61B5/06 , A61B6/022 , A61B6/4441 , A61B6/4464 , A61B6/466
摘要： An apparatus and method is described for determining the location of a object inside a patient. Three dimensional image data of the patient is obtained by an imaging modality such as a C-arm X-ray device. The same or another imaging modality may be used to obtain projection radiographic images, having a coordinate system that can be registered with respect to that of the three dimensional image. The location of one or more features of a medical treatment device such as a needle or a catheter introduced into the imaging filed of view is determined either by an operator or by image analysis, in at least two projection radiographic images, and the position of the feature located in the three-dimensional volume. The projection on a radiographic image of a vector joining a first and a second position is used to assist in guiding the medical treatment device inside of the patient.
摘要翻译：描述了用于确定患者体内物体的位置的装置和方法。通过诸如C臂X射线装置的成像模式获得患者的三维图像数据。可以使用相同或另一种成像模态来获得具有可以相对于三维图像的坐标系进行登记的坐标系的投影放射照相图像。引入到成像视场中的医疗处理装置（例如针或导管）的一个或多个特征的位置由操作者或通过图像分析，至少两个投影放射照相图像和功能位于三维体积。使用连接第一位置和第二位置的矢量的放射线图像上的投影来辅助将患者体内的医疗装置引导。

77. 发明授权

US07495233B2 Fluorescence scanner for molecular signatures 失效
标题翻译：用于分子标记的荧光扫描仪
公开(公告)号：US07495233B2
公开(公告)日：2009-02-24
申请号：US11375948
申请日：2006-03-15
申请人： Marcus Pfister , Wolfgang Strob
发明人： Marcus Pfister , Wolfgang Strob
IPC分类号： H05B35/00
CPC分类号： G01N21/6456 , A61B5/0059 , A61B5/415 , A61B5/418 , G01N2201/0221
摘要： An apparatus detects fluorescence. The apparatus, also known as a fluorescence scanner, includes an image detector, which is embodied for detecting image data in the wavelength range of fluorescent light, and an excitation light source, which is embodied for generating light in a wavelength range suitable for exciting the fluorescence. The apparatus has a guide beam projector, which is embodied for generating a guide beam from light in the visible wavelength range. The guide beam is aimed such that a projection of the guide beam, a region that is detectable by the image detector is displayed. The guide beam allows exact viewing of a body region to be examined possible for the surgeon, which is not possible on the basis only of the light for exciting a fluorescence, at least whenever the excitation light is in the non-visible wavelength range, such as IR or NIR, or is generated directly during the recording of the fluorescence image.
摘要翻译：一种装置检测荧光。该装置也称为荧光扫描器，包括：图像检测器，其被实现为用于检测荧光波长范围内的图像数据;以及激发光源，其被实施用于产生适于激发波长范围的光荧光。该装置具有导光束投影仪，其被实施用于从可见波长范围的光产生引导光束。引导光束被瞄准，使得可以显示引导光束的投影，可以被图像检测器检测的区域。至少每当激发光处于不可见的波长范围内时，引导光束允许精确地观察对外科医生进行检查的身体区域，这对于激发荧光来说是不可能的，这仅仅是用于激发荧光的光。作为IR或NIR，或者在记录荧光图像期间直接产生。

78. 发明申请

US20080089467A1 Method for recording x-ray images of an area lying outside a center of rotation of a C-arm system and the associated C-arm system 有权
公开(公告)号：US20080089467A1
公开(公告)日：2008-04-17
申请号：US11890353
申请日：2007-08-06
申请人： Gunter Lauritsch , Marcus Pfister
发明人： Gunter Lauritsch , Marcus Pfister
IPC分类号： H05G1/02 , H05G1/30
CPC分类号： A61B6/102 , A61B6/4441 , A61B6/4464 , A61B6/487 , A61B6/583 , A61B2090/364
摘要： The invention relates to a method for recording x-ray images with a C-arm system, which comprises an image recording system rotatable about a center of rotation in a recording plane, a number of x-ray fluoroscopic images of an area of interest of an object lying on an object supporting device are recorded at a plurality of angles of rotations by the image recording system, from which one or more cross-sectional images or a three dimensional can be reconstructed. The method is characterized in that the object supporting device is guided synchronously and in a non-colliding manner with the rotation of the image recording system, such that at every angle of rotation at which the recording of an image takes place, the area of interest of the object lies within a beam cone of the x-ray radiation beam of the image recording system.

79. 发明申请

US20070265551A1 Method for delivering a catheter to a target in the brain of a patient and guide wire for a microcatheter for insertion in the brain of a patient 审中-公开
标题翻译：用于将导管输送到患者脑中的靶和用于插入患者脑的微导管的导丝的方法
公开(公告)号：US20070265551A1
公开(公告)日：2007-11-15
申请号：US11789229
申请日：2007-04-24
申请人： Marcus Pfister
发明人： Marcus Pfister
IPC分类号： A61M25/00
CPC分类号： A61M25/09 , A61L31/14 , A61L2400/12 , A61M25/0127 , A61M2025/09133
摘要： The movement of catheters and guide wires for catheters with the aid of magnets is known from the field of cardiology. Conventional magnets are, as a result of their size, not suited to being inserted into the brain of patient, because the vessels there are smaller than the cardiac vessels. To enable the navigation methods proven in cardiology also to be used in neurology, the invention provides a microcatheter having a guide wire, which features magnetic nanoparticles. The magnetic nanoparticles can be provided in the form of a ferrofluid or also as diamond nanoparticles in powder form. This enables navigation of the guide wire and thus ultimately of the catheter in the brain from the outside by way of magnetic fields.
摘要翻译：借助于磁体，用于导管的导管和引导线的运动从心脏病学领域是已知的。作为其尺寸的结果，常规磁体不适于插入患者的脑中，因为其中的血管小于心脏血管。为了使得在心脏病学中证明的导航方法也可用于神经学，本发明提供了一种具有导线的微导管，其具有磁性纳米颗粒。磁性纳米颗粒可以以铁磁流体的形式提供，或者以粉末形式提供为金刚石纳米颗粒。这使得能够通过磁场从外部导航引导线并且因此导致脑中的导管。

80. 发明申请

US20070083102A1 Method for the graphical representation of a medical instrument inserted at least partially into an object under examination 有权
标题翻译：用于至少部分地插入被检查物体的医疗仪器的图形表示的方法
公开(公告)号：US20070083102A1
公开(公告)日：2007-04-12
申请号：US11522261
申请日：2006-09-15
申请人： Marcus Pfister , Bernhard Sandkamp
发明人： Marcus Pfister , Bernhard Sandkamp
IPC分类号： A61B5/05
CPC分类号： A61B90/36 , A61B6/12 , A61B6/4441 , A61B6/541 , A61B2090/364 , G06T7/70 , G06T2207/10072 , G06T2207/30004 , G06T2207/30021
摘要： The invention provides a method for the graphical representation of a medical instrument (3) inserted at least partially into an object under examination (2), with an image (4) representing the medical instrument (3) being generated, in that the instrument image (4) is vectorized (V), with the medical instrument (3) being represented as a polyline (8, 8′).
摘要翻译：本发明提供了一种用于至少部分地插入被检查物体（2）中的医疗器械（3）的图形表示的方法，其中生成了代表医疗器械（3）的图像（4），仪器图像（4）被矢量化（V），医疗器械（3）被表示为折线（8,8'）。

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