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    • 73. 发明授权
    • Cyclopropyl-thienyl-carboxamide as fungicides
    • US07312179B2
    • 2007-12-25
    • US10532847
    • 2003-10-24
    • Josef EhrenfreundHans ToblerHarald Walter
    • Josef EhrenfreundHans ToblerHarald Walter
    • A01N43/36C07D409/00
    • C07D409/12C07D333/36C07D411/12C07D417/12
    • A fungicidally active compound of formula (I): where X is (X1), (X2) or (X3); Het is a 5- or 6-membered heterocyclic ring containing one to three heteroatoms, each independently selected from oxygen, nitrogen and sulphur, provided that the ring is not 1,2,3-triazole, the ring being substituted by groups R4, R5 and R6; R1 and R2 are each, independently, hydrogen, halo or methyl; R3 is optionally substituted C2-12 alkyl, optionally substituted C2-12 alkenyl, optionally substituted C2-12 alkynyl, optionally substituted C3−12 cycloalkyl, optionally substituted phenyl or optionally substituted heterocyclyl; R4, R5 and R6 are each, independently, selected from hydrogen, halo, cyano, nitro, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy(C1-4)alkylene and C 1-4 haloalkoxy(C1-4)alkylene, provided that at least one of R4, R5 and R6 is not hydrogen; and R7 and R8 are each, independently, hydrogen, halogen, C1-4 alkyl or Clue haloalkyl; the invention also relates to the preparation of these compounds, to novel intermediates used in the preparation of these compounds, to the preparation of intermediates, to agrochemical compositions which comprise at least one of the novel compounds as active ingredient and to the use of the active ingredients or compositions in agriculture or horticulture for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi
    • 74. 发明申请
    • Silicon compounds with microbiocidal activity
    • US20060287328A1
    • 2006-12-21
    • US10569343
    • 2004-09-08
    • Josef EhrenfreundClemens LamberthHans ToblerHarald Walter
    • Josef EhrenfreundClemens LamberthHans ToblerHarald Walter
    • C07D417/02C07D413/02C07D409/02C07D403/02A01N43/54A01N43/80A01N43/76A01N43/64
    • C07F7/0812A01N55/00
    • Fungicidal compounds of formula (1): where X is O or S; RING is phenyl or thienyl; Het is a 5- or 6-membered heterocyclic ring containing one to three heteroatoms, each independently selected from oxygen, nitrogen and sulphur, the ring being substituted by one to four groups R4; R1 is hydrogen, optionally substituted (C1-4)alkyl, formyl, optionally substituted (C1-4)alkylC(═O), optionally substituted (C1-4)alkylC(═O)O, optionally substituted (C1-4)alkoxy(C1-4)alkyl, optionally substituted allyl, optionally substituted propargyl or optionally substituted allenyl; each R2 is, independently, halogen, optionally substituted (C1-4)alkyl, optionally substituted (C1-4)alkoxy or optionally substituted (C1-4)alkoxy(C1-4)alkyl; R3 is (CRaRb)m-Cy-(CRcRd)n—Y; each R4 is, independently, selected from halogen, C1-3 alkyl, C1-3 haloalkyl, C1-3alkoxy(C1-3)alkyl and cyano; Ra, Rb, Rc and Rd are each, independently, hydrogen or optionally substituted (C1-4)alkyl; Cy is an optionally substituted carbocyclic or heterocyclic 3-7 membered ring which may be saturated, unsaturated or aromatic and which optionally contains a silicon atom as a ring member; (CRaRb)m and (CRcRd), may be bound either to the same carbon or silicon atom of Cy or to different atoms separated by 1, 2 or 3 ring members; Y is Si(OpZ1)(OqZ2)(O5Z) and provided that Cy contains a silicon atom as a ring member then Y may also be hydrogen; Z is C1-4 alkyl or C2-4 alkenyl (each of which is optionally interrupted by one heteroatom selected from O, S and N and is optionally substituted by one to three independently selected halogen atoms); Z1 and Z2 are, independently, methyl or ethyl; in and n are each, independently, 0, 1, 2 or 3; p, q and s are each, independently, 0 or 1; and r is 0, 1 or 2; or an N-oxide thereof; novel intermediates used in the preparation of these compounds, agrochemical compositions which comprise at least one of the novel compounds as active ingredient and the use of the active ingredients or compositions in agriculture or horticulture for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi.
    • 75. 发明申请
    • Cyclopropyl-thienyl-carboxamide as fungicides
    • US20060030567A1
    • 2006-02-09
    • US10532847
    • 2003-10-24
    • Josef EhrenfreundHans ToblerHarald Walter
    • Josef EhrenfreundHans ToblerHarald Walter
    • C07D409/02A01N43/64A01N43/54
    • C07D409/12C07D333/36C07D411/12C07D417/12
    • A fungicidally active compound of formula (I): where X is (X1), (X2) or (X3); Het is a 5- or 6-membered heterocyclic ring containing one to three heteroatoms, each independently selected from oxygen, nitrogen and sulphur, provided that the ring is not 1,2,3-triazole, the ring being substituted by groups R4, R5 and R6; R1 and R2 are each, independently, hydrogen, halo or methyl; R3 is optionally substituted C2-12 alkyl, optionally substituted C2-12 alkenyl, optionally substituted C2-12 alkynyl, optionally substituted C3−12 cycloalkyl, optionally substituted phenyl or optionally substituted heterocyclyl; R4, R5 and R6 are each, independently, selected from hydrogen, halo, cyano, nitro, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy(C1-4)alkylene and C1-4 haloalkoxy(C1-4)alkylene, provided that at least one of R4, R5 and R6 is not hydrogen; and R7 and R8 are each, independently, hydrogen, halogen, C1-4 alkyl or Clue haloalkyl; the invention also relates to the preparation of these compounds, to novel intermediates used in the preparation of these compounds, to the preparation of intermediates, to agrochemical compositions which comprise at least one of the novel compounds as active ingredient and to the use of the active ingredients or compositions in agriculture or horticulture for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi.