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71. 发明授权

US08470763B2 Alpha-amino-N-substituted amides, pharmaceutical composition containing them and uses thereof 有权
标题翻译： α-氨基-N-取代的酰胺，含有它们的药物组合物及其用途
公开(公告)号：US08470763B2
公开(公告)日：2013-06-25
申请号：US12747485
申请日：2008-12-11
申请人： Fajun Nan , Jia Li , Jian Ding , Gang Liu , Chuanming Xie , Zehong Miao , Wanyi Tai
发明人： Fajun Nan , Jia Li , Jian Ding , Gang Liu , Chuanming Xie , Zehong Miao , Wanyi Tai
IPC分类号： C07D345/00
CPC分类号： C07C237/22 , C07C247/12 , C07C271/22 , C07C323/60 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2603/74 , C07D209/14 , C07D209/20 , C07D233/54 , C07D307/24 , C07D307/94
摘要： Disclosed are a series of α-amino-N-substituted amide compounds having a structure of the following formula, the pharmaceutically acceptable salts thereof, and the pharmaceutical composition comprising the same. The α-amino-N-substituted amide compounds or the pharmaceutically acceptable salts thereof according to the present invention have anti-tumor and/or anti-cancer activities in vivo and in vitro, can effectively depress the growth of various tumor cells and/or cancer cells, and thus can be used in preparing drugs for treating tumors and/or cancers.
摘要翻译：公开了一系列具有下式结构的α-氨基-N-取代酰胺化合物及其药学上可接受的盐，以及包含它们的药物组合物。根据本发明的α-氨基-N-取代的酰胺化合物或其药学上可接受的盐在体内和体外具有抗肿瘤和/或抗癌活性，可以有效抑制各种肿瘤细胞的生长和/或癌细胞，因此可用于制备用于治疗肿瘤和/或癌症的药物。

72. 发明申请

US20130035326A1 BIARYL COMPOUNDS AND METHODS OF USE THEREOF 审中-公开
标题翻译： BIARYL化合物及其使用方法
公开(公告)号：US20130035326A1
公开(公告)日：2013-02-07
申请号：US13390911
申请日：2010-08-18
申请人： Sunny Abraham , Mark W. Holladay , Gang Liu , Shimin Xu
发明人： Sunny Abraham , Mark W. Holladay , Gang Liu , Shimin Xu
IPC分类号： C07D413/12 , C07D498/04 , A61K31/5383 , A61K31/4375 , C07D471/04 , C07D413/14 , A61K31/444 , A61K31/553 , A61K31/4545 , A61K31/506 , A61K31/5377 , A61K31/505 , C07D401/12 , A61K31/497 , A61K31/437 , A61K31/5513 , C07D239/42 , C07D401/04 , A61P29/00 , A61P37/00 , A61P35/00 , A61P35/02 , A61P37/06 , A61P17/02 , A61P13/12 , A61P17/06 , A61P37/08 , A61P11/00 , A61P19/02 , A61P25/00 , A61P19/10 , A61P11/06 , A61P37/02 , A61P31/00 , A61P3/10 , A61P1/00 , A61P1/04 , A61P19/04 , A61K31/4439
CPC分类号： C07D239/42 , A61K31/4353 , A61K31/4375 , A61K31/4427 , A61K31/4439 , A61K31/444 , A61K31/501 , A61K31/506 , A61K31/5375 , A61K31/5377 , A61K31/553 , C07D401/04 , C07D401/12 , C07D413/12 , C07D413/14 , C07D471/04 , C07D498/04
摘要： Provided herein are compounds for treatment of KIT, CSF-1R and/or FLT3 kinase mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.
摘要翻译：本文提供了用于治疗KIT，CSF-1R和/或FLT3激酶介导的疾病的化合物。还提供了包含该化合物的药物组合物和使用该化合物和组合物的方法。

73. 发明申请

US20120326663A1 BATTERY CHARGING APPARATUS FOR ELECTRIC VEHICLE 有权
标题翻译：电动车充电装置
公开(公告)号：US20120326663A1
公开(公告)日：2012-12-27
申请号：US13234480
申请日：2011-09-16
申请人： Peiai You , Gang Liu , Jinfa Zhang
发明人： Peiai You , Gang Liu , Jinfa Zhang
IPC分类号： H02J7/00
CPC分类号： B60L11/1812 , H02J7/0042 , Y02T10/7005 , Y02T10/7072 , Y02T90/127 , Y02T90/14
摘要： A battery charging apparatus for an electric vehicle (EV) or a hybrid electric vehicle (HEV) includes a case chassis, a circuit board and at least one electronic component. The case chassis includes a plurality of side plates, a bottom plate and a receptacle. The circuit board is accommodated within the receptacle of the case chassis. The electronic component includes a passive component body with a plurality of conductive wires and a fixing member for accommodating the passive component body. The conductive wires are electrically connected to the circuit board. The fixing member is fixed on at least one of the side plates and the bottom plate of the case chassis.
摘要翻译：电动车辆（EV）或混合电动车辆（HEV）的电池充电装置包括壳体底架，电路板和至少一个电子部件。壳体底架包括多个侧板，底板和插座。电路板容纳在机壳底盘的插座内。电子部件包括具有多个导电线的无源部件体和用于容纳被动部件主体的固定部件。导线电连接到电路板。固定构件固定在壳体底板的至少一个侧板和底板上。

74. 发明授权

US08334320B2 Methods for chelation therapy 有权
标题翻译：螯合治疗方法
公开(公告)号：US08334320B2
公开(公告)日：2012-12-18
申请号：US12790132
申请日：2010-05-28
申请人： Gang Liu , Ping Men
发明人： Gang Liu , Ping Men
IPC分类号： A61K31/195 , A61K31/519 , A61K31/28 , A61K31/295 , A61K31/19
CPC分类号： A61K31/195 , A61K31/355
摘要： The invention relates to compositions and methods of treatment using an iron chelator, an antioxidant, estrogen, and/or combinations thereof, optionally, linked to a nanoparticle, to treat a subject in need thereof. The compositions and methods may be used to restore or protect the normal functions of osteoblast and osteoclast by depleting iron and inhibiting oxidative damage. The compositions and methods may also be used to increase the bone formation rate in a subject.
摘要翻译：本发明涉及使用铁螯合剂，抗氧化剂，雌激素和/或其组合，任选地与纳米颗粒连接的治疗组合物和方法，以治疗有需要的受试者。组合物和方法可用于通过消耗铁和抑制氧化损伤来恢复或保护成骨细胞和破骨细胞的正常功能。组合物和方法也可用于增加受试者的骨形成速率。

75. 发明申请

US20120272489A1 Multi-Function Clamp For Veterinarian 有权
标题翻译：兽医多功能夹具
公开(公告)号：US20120272489A1
公开(公告)日：2012-11-01
申请号：US13057139
申请日：2010-02-04
申请人： Gonghua Wang , Gang Liu , Xicheng Xie
发明人： Gonghua Wang , Gang Liu , Xicheng Xie
IPC分类号： A61B19/00
CPC分类号： A61B5/0416 , A61B5/0408 , A61B2503/40 , A61D1/00 , Y10T24/44641
摘要： A multi-function clamp for veterinarian, mainly includes upper clip and lower clip; the clamp body is composed by upper clip, lower clip, bolt and torsional spring, wherein the foresaid clamp body installed with connection assembly that has connecting lead wires, and the connection assembly has several installation sections coordinates with the lead wire plug. By adopting the compatibility design, the multi-function clamp for veterinarian could apply to wider areas, a pet clinic equipped with the multi-function clamp for veterinarian is applicable even using the probe-type lead wires, the banana plug lead wires, the snap-type lead wires and the clip-type lead wires simultaneously, which greatly decreases the procurement cost for equipment and accessories, and easier to be operated. Furthermore, by adopting the anti-slip design, the multi-function clamp for veterinarian will improve remarkably for the matter the clamp drops off from the operators or the animal skins, which saves time in operation.
摘要翻译：用于兽医的多功能夹具，主要包括上夹和下夹; 夹具主体由上部夹子，下部夹子，螺栓和扭转弹簧构成，其中安装有连接组件的预定夹具主体具有连接引线，并且连接组件具有与引线插头协调的多个安装部分。通过采用兼容性设计，兽医多功能夹具可以应用于更广泛的领域，配备兽医多功能夹具的宠物诊所甚至使用探针型导线，香蕉插头导线，卡扣型引线和夹式导线，大大降低了设备和配件的采购成本，更易于操作。此外，通过采用防滑设计，兽医多功能夹具可以显着改善夹钳从操作者或动物皮肤上脱落的事件，从而节省时间。

76. 发明授权

US08259442B2 Computer bezel 失效
标题翻译：电脑表圈
公开(公告)号：US08259442B2
公开(公告)日：2012-09-04
申请号：US12870629
申请日：2010-08-27
申请人： Qing-Hui Mi , Hsuan-Tsung Chen , Guang-Yao Lee , Gang Liu
发明人： Qing-Hui Mi , Hsuan-Tsung Chen , Guang-Yao Lee , Gang Liu
IPC分类号： G06F1/16
CPC分类号： G06F1/181
摘要： A computer bezel includes a main body, a door secured to the main body, a pushing member slidably secured to the main body, and a driving member rotatably secured to the main body. The main body defines a through opening. The door is rotated between a closed position, where the door covers the through opening, and an open position, where the door is rotated away from the main body to expose the through opening. The pushing member is slid between a first position, where the pushing member is disengaged from the driving member, and a second position, where the pushing member rotates the driving member. When the driving member is slid from the first position to the second position, the driving member is capable of sliding a tray of a disk drive out of the disk drive, and the door will rotate from the closed position to the open position.
摘要翻译：计算机挡板包括主体，固定到主体的门，可滑动地固定到主体的推动构件和可旋转地固定到主体的驱动构件。主体定义通孔。门在关闭位置，门盖通过开口的关闭位置和打开位置之间旋转，门打开位置，门从主体旋转以露出通孔。推动构件在推动构件与驱动构件脱离的第一位置和第二位置之间滑动，其中推动构件旋转驱动构件。当驱动构件从第一位置滑动到第二位置时，驱动构件能够将盘驱动器的盘从盘驱动器滑出，并且门将从关闭位置旋转到打开位置。

77. 发明授权

US08247719B2 Button device 失效
标题翻译：按钮设备
公开(公告)号：US08247719B2
公开(公告)日：2012-08-21
申请号：US12878000
申请日：2010-09-08
申请人： Guang-Yao Lee , Hsuan-Tsung Chen , Gang Liu , Qing-Hui Mi
发明人： Guang-Yao Lee , Hsuan-Tsung Chen , Gang Liu , Qing-Hui Mi
IPC分类号： H01H13/83
CPC分类号： H01H13/023 , H01H9/161 , H01H2009/164 , H01H2219/044 , H01H2219/06 , H01H2221/072
摘要： A button device includes a button unit, a resilient member, and a switch unit. The button unit includes a button, a transparent power icon member, and a retaining member. The power iron member is attached to the button. The retaining member includes an elastic element, a tray located at one end of the elastic element, and a fixing loop located at the other end of the elastic element. The button and the power iron member are retained on the tray. The tray includes a seat with a hole for receiving an illuminator, and reflects lights of the illuminator to the power icon member. The resilient member is sandwiched between the button unit and the switch unit to reset the button unit back to its original position.
摘要翻译：按钮装置包括按钮单元，弹性构件和开关单元。按钮单元包括按钮，透明电源图标构件和保持构件。电动铁构件附接到按钮。保持构件包括弹性元件，位于弹性元件的一端的托盘和位于弹性元件的另一端的固定环。按钮和电动铁构件保持在托盘上。托盘包括具有用于接收照明器的孔的座，并且将照明器的光反射到电源图标构件。弹性构件被夹在按钮单元和开关单元之间，以将按钮单元重置回其原始位置。

78. 发明申请

US20120028273A1 Particle Analysis Assay for Biomolecular Quantification 审中-公开
标题翻译：用于生物分子量化的粒子分析测定
公开(公告)号：US20120028273A1
公开(公告)日：2012-02-02
申请号：US13269932
申请日：2011-10-10
申请人： Tore Straume , Gang Liu
发明人： Tore Straume , Gang Liu
IPC分类号： G01N33/82 , G01N21/64 , G01N33/53
CPC分类号： G01N33/54333 , C12Q1/6816 , C12Q2563/155 , C12Q2563/143 , C12Q2545/114
摘要： A method is provided for carrying out multi-step separations of objects bearing at least two binding sites. In the first step, a first binder/bead composition is bound to objects that bear the first binding site, and then unbound objects, i.e. objects not bearing the first binding site, are separated from bound objects. In the second step, a second binder/bead composition is bound to the remaining objects that bear the second binding site, and then the objects that are bound to both beads are removed from those objects that are bound to only one bead. The beads can differ in magnetic responsiveness, charge, size, color, and the like, and these differences can be used to carry out the separation steps.
摘要翻译：提供一种用于对具有至少两个结合位点的物体进行多步分离的方法。在第一步骤中，将第一粘合剂/珠粒组合物与承载第一结合位点的物体结合，然后将未结合物体，即不带有第一结合位点的物体与结合的物体分离。在第二步骤中，第二粘合剂/珠粒组合物与承载第二结合位点的剩余物体结合，然后将结合到两个珠粒的物体从仅结合到一个珠粒的那些物体中去除。珠粒可以在磁响应性，电荷，大小，颜色等方面不同，并且这些差异可用于进行分离步骤。

79. 发明授权

US08051282B2 Low voltage reset determination and operational flow modification for microprocessor-controlled devices 有权
标题翻译：用于微处理器控制的器件的低电压复位确定和操作流程修改
公开(公告)号：US08051282B2
公开(公告)日：2011-11-01
申请号：US12080336
申请日：2008-04-02
申请人： Gene Sipinski , Steve Han Ngok Cheng , Gang Liu , Yuan Heng Liu
发明人： Gene Sipinski , Steve Han Ngok Cheng , Gang Liu , Yuan Heng Liu
IPC分类号： G06F1/24
CPC分类号： G06F1/24 , G06F1/305
摘要： A method of identifying a reset condition includes the steps of determining if a stored value is equal to a specified value, executing a first mode if the stored value is not equal to the specified value, and executing a second mode if the stored value is equal to the specified value. The second mode also includes the step of setting the stored value to a value different than the specified value.
摘要翻译：识别复位条件的方法包括以下步骤：确定存储值是否等于指定值，如果所存储的值不等于指定值，则执行第一模式，如果所存储的值相等则执行第二模式到指定的值。第二模式还包括将存储值设置为与指定值不同的值的步骤。

80. 发明申请

US20110156643A1 HIGH-VOLTAGE BATTERY CHARGING SYSTEM FOR USE IN ELECTRIC VEHICLE 审中-公开
标题翻译：用于电动汽车的高压电池充电系统
公开(公告)号：US20110156643A1
公开(公告)日：2011-06-30
申请号：US12978782
申请日：2010-12-27
申请人： Chin-Hou Chen , Han Li , Ko-Yu Hsiao , Gang Liu
发明人： Chin-Hou Chen , Han Li , Ko-Yu Hsiao , Gang Liu
IPC分类号： H02J7/00
CPC分类号： B60L58/20 , B60L53/20 , B60L2270/147 , H02J7/022 , H02M1/4225 , H02M2001/007 , Y02T10/7005 , Y02T10/7066 , Y02T10/7072 , Y02T10/92 , Y02T90/127 , Y02T90/14
摘要： A high-voltage battery charging system is installed in a vehicle body of the electric vehicle for charging a high-voltage battery unit within the vehicle body. The high-voltage battery charging system includes a rectifier circuit, a power factor correction circuit and a non-isolated DC-DC converting circuit. The rectifier circuit is connected to a common terminal for rectifying an AC input voltage into a rectified voltage. The power factor correction circuit is connected to the rectifier circuit and a bus for increasing a power factor and generating a bus voltage. The non-isolated DC-DC converting circuit is connected to the power factor correction circuit and the high-voltage battery unit for charging the high-voltage battery unit, wherein no transformer is included in the non-isolated DC-DC converting circuit.
摘要翻译：高压电池充电系统安装在电动车辆的车身中，用于对车体内的高压电池单元充电。高压电池充电系统包括整流电路，功率因数校正电路和非隔离DC-DC转换电路。整流电路连接到公共端子，用于将AC输入电压整流为整流电压。功率因数校正电路连接到整流电路和总线，用于增加功率因数并产生总线电压。非隔离DC-DC转换电路连接到功率因数校正电路和用于对高压电池单元充电的高压电池单元，其中非隔离DC-DC转换电路中不包括变压器。

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