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    • 71. 发明申请
    • Production Process of Glycolide
    • 乙交酯的生产工艺
    • US20110263875A1
    • 2011-10-27
    • US13142012
    • 2009-12-09
    • Shigeru SuzukiKazuyuki YamaneToshihiko OnoKazuhiko Sunagawa
    • Shigeru SuzukiKazuyuki YamaneToshihiko OnoKazuhiko Sunagawa
    • C07D319/12
    • C07D319/12
    • The invention provides a production process of glycolide comprising the respective steps of: Step 1 of heating a mixture containing a glycolic acid oligomer and a high boiling polar organic under normal or reduced pressure to reflux the mixture and at that time, conducting a total reflux operation in a reflux time within a range of 0.1 to 20 hours under conditions that substantially the whole amount of a distillate distilled out of a reflux system containing the mixture is refluxed into the reflux system; Step 2 of heating the mixture after the total reflux operation or a mixture obtained by adding the high boiling polar organic solvent to a glycolic acid oligomer component recovered from the mixture after the total reflux operation to conduct depolymerization; and Step 3 of collecting glycolide from a co-distillate.
    • 本发明提供了一种乙交酯的制备方法,其包括以下各步骤:步骤1,在正常或减压下加热含有乙醇酸低聚物和高沸点极性有机物的混合物以回流混合物,并且此时进行总的回流操作 在从含有该混合物的回流系统蒸馏出的基本上全部量的馏出物回流至回流系统的条件下,在0.1至20小时的范围内的回流时间内, 在全部回流操作之后加热混合物的步骤2或通过在完全回流操作后从混合物中回收的乙醇酸低聚物组分加入高沸点极性有机溶剂而获得的混合物进行解聚; 和从共馏出物收集乙交酯的步骤3。