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71. 发明申请

US20070233250A1 SYSTEMS FOR TREATING BONE 审中-公开
标题翻译：治疗骨骼的系统
公开(公告)号：US20070233250A1
公开(公告)日：2007-10-04
申请号：US11672434
申请日：2007-02-07
申请人： John Shadduck
发明人： John Shadduck
IPC分类号： A61F2/44
CPC分类号： A61B17/7095 , A61B18/02 , A61B18/08 , A61B18/1206 , A61B2017/564
摘要： The present invention relates in certain embodiments to medical devices for treating vertebral compression fractures. In one embodiment, the invention relate to systems for introducing fill material into a vertebral body that slowly expands vertebral height without explosive balloon expansion as in kyphoplasty. The system provides a fill material that infills a vertebra without flowable bone cement as used in kyphoplasty and vertebropalsty procedures. Thus, the bone fill system prevents the possibility of extravasation of material into the spinal canal which occurs in a significant number of kyphoplasty and vertebropalsty procedures. An energy source can apply energy to a substantially rigid implant material in order to soften, melt, or fracture the implant material to infill a vertebral body.
摘要翻译：本发明在某些实施例中涉及用于治疗脊椎压缩性骨折的医疗装置。在一个实施例中，本发明涉及用于将填充材料引入椎体中的系统，该椎体缓慢地扩大脊椎高度而没有爆炸性气囊膨胀，如在椎体后凸成形术中。该系统提供填充椎体的填充材料，不需要可流动的骨水泥，如在脊柱后凸成形术和椎板植入术中使用的。因此，骨填充系统防止材料外渗到脊柱管中的可能性，其发生在大量的脊柱后凸成形术和椎间盘手术中。能量源可以将能量施加到基本上刚性的植入材料上，以便软化，熔化或折断植入材料以填充椎体。

72. 发明申请

US20070208353A1 INSTRUMENTS AND TECHNIQUES FOR CONTROLLED REMOVAL OF EPIDERMAL LAYERS 有权
标题翻译：用于控制去除表层的仪器和技术
公开(公告)号：US20070208353A1
公开(公告)日：2007-09-06
申请号：US11739615
申请日：2007-04-24
申请人： John Shadduck
发明人： John Shadduck
IPC分类号： A61B17/50
CPC分类号： A61B17/545 , A61B17/50 , A61B17/54 , A61B2017/00761 , A61B2017/320004 , A61B2217/005 , A61B2217/007 , A61M1/0064 , A61M35/00
摘要： An instrument and technique for the removal of epidermal layers in a controlled manner utilizing a hand-held instrument with a working end that (i) a vacuum aspiration system, (ii) a source for delivery of a sterile fluids or pharmacological agents to the skin; and (iii) a skin interface surface in the working end that has specially shape structure for abrading surface layers of the patient's epidermis as the working end is moved over the patient's skin while at the same time causing rapid penetration of the fluids into the skin for therapeutic purposes. Movement of the working end across the skin causes abrasion of the surface layers in a path over the patient's skin. The method of the invention may be used in a periodic treatment for the removal of superficial skin layers that enhances the synthesis of dermal collagen aggregates by inducing the body's natural wound healing response. The method of the invention creates more normal dermal architectures in skin with limited depths of skin removal by the series of superficial treatments that may be comparable to the extent of neocollagenesis caused by a deep skin removal treatment (e.g., CO2 laser skin removal).
摘要翻译：一种利用具有工作端的手持式仪器以受控方式去除表皮层的仪器和技术，该工具包括（i）真空抽吸系统，（ii）用于将无菌流体或药物剂递送至皮肤的源 ; 和（iii）工作端中的皮肤界面表面，其具有特殊的形状结构，用于当工作端移动到患者皮肤上同时使流体快速渗透到皮肤中时，用于研磨患者表皮的表面层治疗目的。穿过皮肤的工作端的移动导致患者皮肤上的路径中的表面层的磨损。本发明的方法可用于周期性治疗以通过诱导人体的自然伤口愈合反应来去除表皮层，从而增强真皮胶原聚集体的合成。本发明的方法在皮肤中产生更正常的皮肤结构，通过一系列表面处理具有有限的皮肤去除深度，其可以与由深层皮肤去除处理引起的新胶原形成的程度相当（例如， SUP>激光皮肤去除）。

73. 发明申请

US20060229598A1 Supercavitating medical probe and method of use 审中-公开
公开(公告)号：US20060229598A1
公开(公告)日：2006-10-12
申请号：US11300689
申请日：2005-12-14
申请人： John Shadduck
发明人： John Shadduck
IPC分类号： A61B18/14
CPC分类号： A61B17/320068 , A61B18/148 , A61B2017/22014 , A61B2018/00208 , A61B2018/1861 , A61B2218/002 , A61B2218/007 , A61F9/0079 , A61N7/02 , A61N7/022
摘要： An electrosurgical working end that utilizes supercavitation phenomenon for controlled application of electrosurgical energy to tissue. In one preferred method of the invention, the system utilizes an electrosurgical surface that is rotatable in a liquid substance at very high surface velocities capable of localized lowering of the pressure of the substance below its saturated vapor pressure to cause supercavitation, and contemporaneously applying electrical energy from the electrosurgical surface across the cavity to ablate adjacent tissue. The system creates supercavitation with surface velocities of greater than about 70 m/sec in a liquid substance by means of high speed rotation and optionally ultrasound actuation.

74. 发明申请

US20060087614A1 Adaptive optic lens system and method of use 有权
标题翻译：自适应光学透镜系统及其使用方法
公开(公告)号：US20060087614A1
公开(公告)日：2006-04-27
申请号：US11284068
申请日：2005-11-21
申请人： John Shadduck
发明人： John Shadduck
IPC分类号： G02C7/02
CPC分类号： G02C7/041 , A61F2/145 , A61F2/16 , A61F2/1635 , A61F2/1637 , A61F2/1648 , A61F2210/0014 , G02B27/0068 , G02C7/021 , G02C7/04 , G02C7/049 , G02C2202/16 , G02C2202/22
摘要： An lens for correcting human vision, for example an IOL, contact lens or corneal inlay or onlay, that carries and interior phase or layer comprising a pattern of individual transparent adaptive displacement structures. In one embodiment, the displacement structures are actuated by a shape memory polymer (SMP) material or other polymer that is adjustable in shape in response to applied energy. The SUP can be designed to be selectively adjustable in volumetric dimension, modulus of elasticity and/or permeability. The adaptive optic means of the invention can be used to create highly localized surface corrections in the lens to correct higher order aberrations—which types of surfaces cannot be fabricated into and IOL and then implanted. The system of displacement structures also can provide spherical corrections in the lens.
摘要翻译：用于校正人类视觉的镜片，例如IOL，隐形眼镜或角膜嵌体或镶嵌物，其携带和内部相或包含单独的透明自适应位移结构的图案的层。在一个实施例中，位移结构由形状记忆聚合物（SMP）材料或响应于所施加的能量调节形状的其它聚合物致动。 SUP可以设计成可以在体积尺寸，弹性模量和/或渗透性中选择性地调节。本发明的自适应光学装置可以用于在透镜中产生高度局部化的表面校正，以校正高阶像差 - 哪些类型的表面不能被制造和IOL然后植入。位移结构的系统也可以在透镜中提供球面校正。

75. 发明申请

US20060061729A1 Adaptive optic lens and method of making 有权
标题翻译：自适应光学透镜及其制作方法
公开(公告)号：US20060061729A1
公开(公告)日：2006-03-23
申请号：US11214538
申请日：2005-08-29
申请人： John Shadduck
发明人： John Shadduck
IPC分类号： G02C7/04
CPC分类号： G02B3/14 , A61F2/145 , A61F2/1613 , A61F2/1635 , A61F2210/0014 , G02B26/06
摘要： An lens for correcting human vision, for example an IOL, contact lens or corneal inlay or onlay, that carries and interior phase or layer comprising a pattern of individual transparent adaptive displacement structures. In the exemplary embodiments, the displacement structures are actuated by shape change polymer that adjusts a shape or other parameter in response to applied energy that in turn displaces a fluid media within the lens that actuates a flexible lens surface. The adaptive optic means of the invention can be used to create highly localized surface corrections in the lens to correct higher order aberrations-which types of surfaces cannot be fabricated into and IOL and then implanted. The system of displacement structures also can provide spherical corrections in the lens.
摘要翻译：用于校正人类视觉的镜片，例如IOL，隐形眼镜或角膜嵌体或镶嵌物，其携带和内部相或包含单独的透明自适应位移结构的图案的层。在示例性实施例中，位移结构由形状变化聚合物致动，聚合物响应于所施加的能量而调节形状或其它参数，所述能量又使透镜内的流体介质移动，该流体介质致动柔性透镜表面。本发明的自适应光学装置可以用于在透镜中产生高度局部化的表面校正，以校正高阶像差 - 哪些类型的表面不能被制造和IOL然后植入。位移结构的系统也可以在透镜中提供球面校正。

76. 发明申请

US20050267321A1 Elastomeric magnetic nanocomposite biomedical devices 审中-公开
标题翻译：弹性磁性纳米复合生物医学装置
公开(公告)号：US20050267321A1
公开(公告)日：2005-12-01
申请号：US11141771
申请日：2005-06-01
申请人： John Shadduck
发明人： John Shadduck
IPC分类号： A61F5/00 , A61F5/56 , A61M37/00 , A61N2/00 , A61N2/06
CPC分类号： A61F5/0079 , A61F5/56 , A61N2/00 , A61N2/06
摘要： A biomedical device of a smart elastomer, more particularly relating to a class of low modulus elastomers with dispersed, aligned magnetic nanoparticles therein that allow for controlling the flexural modulus of the device and engaged tissue in response to an applied magnetic field. An exemplary embodiment is used for treating obstructive airway syndrome wherein one or more implants including an elastomer magnetic nanocomposite are placed in a patient's soft palate. During sleep, a source of magnetic flux is applied to stiffen the implants to dampen vibrations in tissue which occur in snoring and sleep apnea episodes. The magnetic flux is provided by a permanent magnet or by a magnetic field source coupled to a controller for modulating the stiffness of the implant(s). In similar embodiments, the controlled modulus implants can be used to treat various anatomic structures such as upper airway tissue, oral cavity tissue, gastrointestinal tract tissue, urinary tract tissue, cardiovascular tissue, muscle tissue, penile tissue, sphincters and skin.
摘要翻译：一种智能弹性体的生物医学装置，更具体地涉及其中具有分散的对准的磁性纳米颗粒的一类低弹性体，其允许响应于所施加的磁场来控制装置和被接合的组织的弯曲模量。一个示例性实施例用于治疗阻塞性气道综合征，其中将包括弹性体磁性纳米复合物的一个或多个植入物置于患者的软腭中。在睡眠期间，施加磁通量来加强植入物以抑制在打鼾和睡眠呼吸暂停发作中发生的组织中的振动。磁通由永磁体或耦合到控制器的磁场源提供，用于调制植入物的刚度。在类似的实施方案中，受控模量植入物可用于治疗各种解剖结构，例如上呼吸道组织，口腔组织，胃肠道组织，尿道组织，心血管组织，肌肉组织，阴茎组织，括约肌和皮肤。

77. 发明申请

US20050143814A1 Lens system and method for power adjustment 有权
标题翻译：镜头系统和功率调节方法
公开(公告)号：US20050143814A1
公开(公告)日：2005-06-30
申请号：US11015918
申请日：2004-12-17
申请人： Victor Esch , John Shadduck
发明人： Victor Esch , John Shadduck
IPC分类号： A61F2/16 , G02C7/04
CPC分类号： A61F2/1613 , A61F2/1601 , A61F2/1635 , A61F2/1648 , G02C7/04 , G02C7/085
摘要： A lens is provided that having optical parameters that may be adjusted in-situ, and is particularly useful as an IOL for use in cataract patients that require an adjustment in the optical power of the lens post-implantation. In one embodiment, the lens body carries an array of interior fluid-filled cells in which fluid is controllably moved upon application of energy from an external source to move a fluid media into or out of the cells to thereby alter the lens surface shape.
摘要翻译：提供了具有可以原位调整的光学参数的透镜，并且作为需要调整透镜植入后光学功率的白内障患者的IOL特别有用。在一个实施例中，透镜体携带内部流体填充单元的阵列，其中流体在施加来自外部源的能量时可控地移动，以将流体介质移入或移出单元，从而改变透镜表面形状。

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