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71. 发明申请

US20070154466A1 Internal medical devices containing peroxide-converting catalysts 审中-公开
标题翻译：含有过氧化物转化催化剂的内部医疗器械
公开(公告)号：US20070154466A1
公开(公告)日：2007-07-05
申请号：US11322924
申请日：2005-12-30
申请人： Jan Weber , Eric Nielson
发明人： Jan Weber , Eric Nielson
IPC分类号： A61F2/02 , A61K38/44 , A61K31/727
CPC分类号： A61L31/082 , A61K31/727 , A61K38/44 , A61L31/128 , A61L31/148 , C12Y111/01006
摘要： The present invention is directed to implantable and insertable medical devices (also referred to herein as internal medical devices), which contain one or more peroxide-converting catalysts. According to an aspect of the invention, internal medical devices are provided, which contain (a) a substrate and (b) a peptide-containing, peroxide-converting catalyst disposed over at least a portion of the substrate. According to another aspect of the invention, internal medical devices are provided which contain a catalyst binding entity. The catalyst binding entity is adapted to bind to endogenous peroxide-converting catalyst upon implantation or insertion of the devices into patients. In another aspect of the invention, internal medical devices are provided which contain a biodegradable region that in turn contains a peroxide-converting catalyst. These devices release the catalyst in conjunction with degradation of the biodegradable region. In yet another aspect of the invention, internal medical devices are provided which contain a substrate, a multilayer region disposed over at least a portion of the substrate, and a peroxide-converting catalyst disposed within the multilayer region. The multilayer region, in turn, contains a plurality of charged layers of alternating charge, which charged layers further contain a plurality of polyelectrolyte containing layers.
摘要翻译：本发明涉及含有一种或多种过氧化物转化催化剂的可植入和可插入医疗装置（本文也称为内部医疗装置）。根据本发明的一个方面，提供了内部医疗装置，其包含（a）底物和（b）设置在所述基底的至少一部分上的含肽的过氧化物转化催化剂。根据本发明的另一方面，提供了含有催化剂结合实体的内部医疗装置。催化剂结合实体适于在将装置植入或插入患者体内时结合内源性过氧化物转化催化剂。在本发明的另一方面，提供了含有可生物降解区域的内部医疗装置，其又含有过氧化物转化催化剂。这些装置与可生物降解区域的降解一起释放催化剂。在本发明的另一方面，提供了内置医疗装置，其包含基材，设置在基材的至少一部分上的多层区域和设置在多层区域内的过氧化物转化催化剂。多层区域又包含多个交替电荷的带电层，该带电层还含有多个含聚电解质的层。

72. 发明申请

US20070129748A1 Selectively coated medical balloons 审中-公开
标题翻译：选择性涂层医用气球
公开(公告)号：US20070129748A1
公开(公告)日：2007-06-07
申请号：US11296680
申请日：2005-12-07
申请人： Tracee Eidenschink , Raed Rizq , David Elizondo , Jan Weber , Kevin Barry
发明人： Tracee Eidenschink , Raed Rizq , David Elizondo , Jan Weber , Kevin Barry
IPC分类号： A61M29/00
CPC分类号： A61M25/10 , A61F2/958 , A61M25/1038 , A61M2025/1004 , A61M2025/1088
摘要： An expandable medical balloon having predetermined strategic arrangement of differentially lubricious surfaces.
摘要翻译：具有预定的差异润滑表面的策略布置的可膨胀医用气囊。

73. 发明申请

US20070062933A1 Resonator with adjustable capacitor for medical device 失效
标题翻译：谐振器用于医疗设备的可调电容器
公开(公告)号：US20070062933A1
公开(公告)日：2007-03-22
申请号：US11209219
申请日：2005-08-23
申请人： Jan Weber
发明人： Jan Weber
IPC分类号： H05B6/36
CPC分类号： G01R33/286 , A61B5/055 , A61F2/82 , G01R33/3628 , Y10T29/49117
摘要： An apparatus, system and method of a resonator device with an adjustable capacitor for allowing the resonance frequency (F) of the resonator device to continue to be matched to the Larmor frequency of the MRI system. The resonator device includes an inductor coil, a conductive member, a sleeve having first and second sockets that receive at least portions of the inductor coil and the conductive member as electrodes to provide a capacitor structure. Dielectric material can be positioned between at least the first and second sockets, where changes in the cross sectional area defined by the induction coil cause changes in the capacitance value (C) as one or more of the electrodes move within the socket. Changes in the inductance and the capacitance values allow for the resonance frequency (F) of the resonator device to continue to be matched to the Larmor frequency of the MRI system.
摘要翻译：具有可调电容器的谐振器装置的装置，系统和方法，用于允许谐振器装置的谐振频率（F）继续与MRI系统的拉莫尔频率匹配。谐振器装置包括电感线圈，导电构件，具有第一和第二插座的套筒，该套管至少容纳电感器线圈和导电构件的至少一部分作为电极以提供电容器结构。介电材料可以位于至少第一和第二插座之间，其中由感应线圈限定的横截面积的变化引起电容值（C）的变化，因为一个或多个电极在插座内移动。电感和电容值的变化允许谐振器装置的谐振频率（F）继续与MRI系统的拉莫尔频率匹配。

74. 发明申请

US20070038176A1 Medical devices with machined layers for controlled communications with underlying regions 审中-公开
标题翻译：具有加工层的医疗设备，用于与底层区域进行控制通信
公开(公告)号：US20070038176A1
公开(公告)日：2007-02-15
申请号：US11174821
申请日：2005-07-05
申请人： Jan Weber , Thomas Holman
发明人： Jan Weber , Thomas Holman
IPC分类号： A61M31/00 , A61M37/00
CPC分类号： A61L27/50
摘要： According to an aspect of the present invention, implantable or insertable medical devices (also referred to as internal medical devices) are provided. These medical devices include at least one machined layer, at least a portion of which is disposed over at least one underlying region (e.g., a therapeutic agent containing region, a catalytic region, etc.). The at least one machined layer contains a plurality of excavated regions which promote the transport of molecular species across the machined layer. An advantage of the present invention is that medical devices are provided, in which the transport of species into the medical device, out of the medical device, or both are controlled, and may be customized, as desired.
摘要翻译：根据本发明的一个方面，提供了可植入或可插入的医疗装置（也称为内部医疗装置）。这些医疗装置包括至少一个加工层，其至少一部分设置在至少一个下部区域（例如，治疗剂容纳区域，催化区域等）上。所述至少一个加工层包含多个挖掘区域，其促进分子物质跨过加工层的运输。本发明的一个优点是提供了医疗装置，其中可以根据需要将物种运送到医疗装置，医疗装置或两者中进行控制，并且可以被定制。

75. 发明申请

US20070032861A1 MRI resonator system with stent implant 有权
标题翻译：具有支架植入物的MRI共振器系统
公开(公告)号：US20070032861A1
公开(公告)日：2007-02-08
申请号：US11198961
申请日：2005-08-08
申请人： Jan Weber , Dave Sogard , John Blix , David Friesen
发明人： Jan Weber , Dave Sogard , John Blix , David Friesen
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61B2090/3958 , A61F2250/0045
摘要： A stent is adapted to be implanted into the lumen of a vessel. The stent includes struts and a resonating circuit tuned to the resonating frequency of a magnetic resonance imaging system. The resonant circuit is constructed of at least one inductor and at least one capacitor. The inductor is wound about at least one of the struts.
摘要翻译：支架适于植入血管内腔。支架包括支柱和调谐到磁共振成像系统的谐振频率的谐振电路。谐振电路由至少一个电感器和至少一个电容器构成。电感器围绕至少一个支柱缠绕。

76. 发明申请

US20060287705A1 Resonator for medical device 有权
公开(公告)号：US20060287705A1
公开(公告)日：2006-12-21
申请号：US11136259
申请日：2005-05-24
申请人： Jan Weber
发明人： Jan Weber
IPC分类号： A61F2/06
CPC分类号： A61F2/82 , A61B2090/3954 , A61F2/91 , G01R33/288
摘要： A device resonator for medical device is provided. The resonator device includes a helical structure and a capacitor structure. The resonator device can be used in conjunction with a medical device, including a stent.

77. 发明申请

US20060271093A1 Fiber mesh controlled expansion balloon catheter 有权
标题翻译：纤维网控膨胀气囊导管
公开(公告)号：US20060271093A1
公开(公告)日：2006-11-30
申请号：US11139253
申请日：2005-05-27
申请人： Thomas Holman , Jan Weber
发明人： Thomas Holman , Jan Weber
IPC分类号： A61M29/00
CPC分类号： A61F2/958 , A61F2/90 , A61F2/954 , A61M25/10 , A61M2025/1081 , A61M2025/1084
摘要： A medical device having a catheter shaft having a distal portion and a proximal portion, a medical balloon co-axially mounted on the distal portion of the catheter shaft and a tubular mesh wrapped around the balloon, wherein the mesh strengthens and reinforced the balloon and may be manipulation to dictate the shape of the balloon and to squeeze the balloon down onto the catheter shaft during deflation of the balloon.
摘要翻译：一种具有导管轴的医疗装置，其具有远侧部分和近端部分，同轴地安装在导管轴的远端部分上的医疗气囊和缠绕在气囊上的管状网状物，其中，网状物加强并加强气囊，并且可以操纵以指示气球的形状并且在气球收缩期间将气囊向下挤压到导管轴上。

78. 发明申请

US20060184112A1 Medical devices 有权
公开(公告)号：US20060184112A1
公开(公告)日：2006-08-17
申请号：US11060093
申请日：2005-02-17
申请人： Daniel Horn , John Chen , Jan Weber , Thomas Holman
发明人： Daniel Horn , John Chen , Jan Weber , Thomas Holman
IPC分类号： A61F2/06
CPC分类号： A61M25/104 , A61F2002/9583 , A61F2250/0068 , A61L29/126 , A61M2025/1086
摘要： Medical devices and related methods are disclosed.

79. 发明申请

US20060182873A1 Medical devices 审中-公开
标题翻译：医疗设备
公开(公告)号：US20060182873A1
公开(公告)日：2006-08-17
申请号：US11060151
申请日：2005-02-17
申请人： Leo Klisch , Jan Weber , Thomas Holman , Scott Schewe , Afsar Ali , Richard Noddin , James Shippy , Karl Jagger , Jan Seppala
发明人： Leo Klisch , Jan Weber , Thomas Holman , Scott Schewe , Afsar Ali , Richard Noddin , James Shippy , Karl Jagger , Jan Seppala
IPC分类号： A61L33/00
CPC分类号： A61B17/320725 , A61B2017/22061 , A61M25/10 , A61M25/1029 , A61M25/1038 , A61M2025/1031 , A61M2025/1075 , A61M2025/1086 , A61M2025/1088
摘要： Medical devices, for example, those that have balloons, and methods of making the devices are described. In some embodiments, a method includes providing a medical balloon having a first cone portion and a body portion, and removing material from an outer surface the body portion of the balloon such that the balloon includes a first region and a second region, the first region being recessed relative to the second region.
摘要翻译：描述了医疗设备，例如具有气球的设备，以及制造设备的方法。在一些实施例中，一种方法包括提供具有第一锥形部分和主体部分的医疗气囊，以及从球囊的主体部分的外表面移除材料，使得球囊包括第一区域和第二区域，第一区域相对于第二区域凹进。

80. 发明申请

US20060178576A1 Resonator for medical device 有权
标题翻译：医疗器械共振器
公开(公告)号：US20060178576A1
公开(公告)日：2006-08-10
申请号：US11207304
申请日：2005-08-19
申请人： Jan Weber , Matthew Miller
发明人： Jan Weber , Matthew Miller
IPC分类号： A61B5/05
CPC分类号： A61F2/90 , A61F2/88 , G01R33/28 , G01R33/34046 , G01R33/34053 , G01R33/34084
摘要： A resonator device for medical device is provided. The resonator device includes a helical structure and a capacitor structure. The resonator device can be used in conjunction with a medical device, including a stent.
摘要翻译：提供了一种用于医疗装置的谐振器装置。谐振器装置包括螺旋结构和电容器结构。谐振器装置可以与包括支架的医疗装置结合使用。

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