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71. 发明授权

US5376555A Method for testing breath alcohol with discrimination between alveolar and upper respiratory tract alcohol 失效
标题翻译：用于检测呼吸酒精的方法，区分肺泡和上呼吸道酒精
公开(公告)号：US5376555A
公开(公告)日：1994-12-27
申请号：US202282
申请日：1994-02-25
申请人： Glenn C. Forrester , Roger Allen , Roger Herrera , Daniel S. Goldberger , James R. Braig
发明人： Glenn C. Forrester , Roger Allen , Roger Herrera , Daniel S. Goldberger , James R. Braig
IPC分类号： G01N33/497 , G01N21/61
CPC分类号： A61B5/097 , G01N33/4972 , Y10S436/90 , Y10T436/204165 , Y10T436/204998
摘要： A method and infrared sensing device for determining the concentration of alveolar alcohol in a breath sample exhaled by a subject into an infrared sensing device. The presence of alcohol from the upper respiratory tract of the subject is detected by continuously monitoring alcohol and carbon dioxide, normalizing alcohol values with respect to carbon dioxide, calculating a difference between normalized alcohol concentration and carbon dioxide concentration over time, integrating (summing) the difference, and comparing the integrated difference with a threshold. This technique accurately and consistently detects the presence of mouth alcohol in the sample before the presence of carbon dioxide which originates in deep lung breath.
摘要翻译：一种用于确定受试者呼出的呼吸样品中的肺泡醇浓度成红外感测装置的方法和红外感测装置。通过连续监测酒精和二氧化碳，对二氧化碳标准化酒精度值，计算标准化酒精浓度与二氧化碳浓度之间的差异随时间的推移，检测来自受试者上呼吸道的酒精含量（总和）差异，并将积分差异与阈值进行比较。该技术在二氧化碳的存在之前准确且一致地检测出样品中口腔醇的存在，这种二氧化碳起源于深肺呼吸。

72. 发明授权

US5296706A Shutterless mainstream discriminating anesthetic agent analyzer 失效
标题翻译：快门主流鉴别麻醉剂分析仪
公开(公告)号：US5296706A
公开(公告)日：1994-03-22
申请号：US985793
申请日：1992-12-02
申请人： James R. Braig , Daniel S. Goldberger , Mark L. Yelderman , Roger O. Herrera
发明人： James R. Braig , Daniel S. Goldberger , Mark L. Yelderman , Roger O. Herrera
IPC分类号： G01J5/06 , G01J5/12 , G01N21/31 , G01N21/35 , G01J5/2
CPC分类号： G01N21/3581 , G01N21/3504 , G01J2005/066 , G01J5/12 , G01N2021/3129 , G01N2021/3166
摘要： An anesthetic agent analyzer having six or more independent analytical channels, where each channel comprises a first thermopile which receives incident infrared radiation and a second thermopile behind the first thermopile which is blocked from the incident infrared radiation and thus serves as a reference for detecting ambient temperature variations. The first and second thermopiles are connected in a "parallel opposed" fashion so that the effects of ambient temperature variations automatically cancel and the detectors may be readily configured in a detector package. The anesthetic agent analyzer of the invention is designed for use with a wideband infrared radiation source so that anesthetic agents having characteristic absorption bands in the far infrared wavelength range (6-15 microns) may be more readily detected and discriminated. When implemented in a mainstream configuration, a disposable airway adapter with windows formed of polypropylene or some other suitable window material which minimally attenuates the infrared energy at the wavelengths of interest is also used. The concentrations of the discriminated anesthetic agent gases are then calculated using a second order polynomial equation having cross product terms. By connecting the first and second thermopiles in a back to back configuration, the detector device of the invention permits twice as many independent analytical channels to be provided in the same substrate area, with the resultant reduction in ambient temperature gradients.
摘要翻译：具有六个或更多个独立分析通道的麻醉剂分析器，其中每个通道包括接收入射的红外辐射的第一热电堆和第一热电堆后面的第二热电堆，其被阻挡入射的红外辐射，因此用作检测环境温度的参考变化。第一和第二热电堆以“平行相对”的方式连接，使得环境温度变化的影响自动消除，并且检测器可以容易地配置在检测器封装中。本发明的麻醉剂分析仪被设计用于宽带红外辐射源，从而可以更容易地检测和鉴别具有远红外波长范围（6-15微米）特征吸收带的麻醉剂。当以主流配置实施时，还使用具有由聚丙烯形成的窗口的一次性气道适配器或一些其它合适的窗口材料，其最小程度地衰减感兴趣的波长处的红外能量。然后使用具有交叉乘积项的二阶多项式方程来计算鉴别的麻醉剂气体的浓度。通过以背靠背的形式连接第一和第二热电堆，本发明的检测器装置允许在同一衬底区域中提供两倍的独立分析通道，从而降低环境温度梯度。

73. 外观设计

USD342135S Airway adapter 失效
公开(公告)号：USD342135S
公开(公告)日：1993-12-07
申请号：US784047
申请日：1991-10-28
申请人： Daniel S. Goldberger , William J. Wohltmann , James R. Braig , Mark L. Yelderman
设计人： Daniel S. Goldberger , William J. Wohltmann , James R. Braig , Mark L. Yelderman

74. 发明授权

US5932877A High performance side stream infrared gas analyzer 失效
标题翻译：高性能侧流红外气体分析仪
公开(公告)号：US5932877A
公开(公告)日：1999-08-03
申请号：US842812
申请日：1997-04-17
申请人： James R. Braig , Daniel S. Goldberger
发明人： James R. Braig , Daniel S. Goldberger
IPC分类号： A61B5/097 , G01N21/35 , G01M21/35
CPC分类号： G01N21/3504 , A61B5/097
摘要： An side stream infrared gas analyzer for detecting the concentration of a gaseous component of a substantially gaseous flow stream such as the expired air of a patient under anesthesia. The infrared gas analyzer comprises an infrared energy detector, a sample cell, and an infrared energy source which are designed to be small and to consume relatively little electrical power. The infrared energy detector converts the received incident radiation into at least one electrical signal representative of the received incident radiation and is preferably mounted directly onto a printed circuit board containing signal processing circuitry which processes the electrical detection signals provided by the infrared energy detector. The infrared energy detector also has a first infrared transmissive window on a detection side thereof through which the incident radiation passes for detection. The sample cell is preferably mounted on the detection side of the infrared energy detector and receives at least a portion of the substantially gaseous flow stream from the patient and directs the received portion to a detection volume which shares the first infrared transmissive window of the infrared energy detector on one side thereof. The infrared energy source is then mounted on the side of the sample cell opposite the infrared energy detector so that emitted infrared energy passes through a second infrared transmissive window which is shared by the infrared energy source and a side of the detection volume opposite the infrared energy detector. After passing through the second infrared transmissive window, the infrared energy from the infrared source passes through the detection volume for absorption by the gaseous component and then through the first infrared transmissive window for detection by the infrared energy detector. The concentration of the gas constituent is then calculated from the resulting absorption signal.
摘要翻译：一种侧流红外气体分析仪，用于检测基本上气态的流动流的气体组分的浓度，例如麻醉下患者的呼出空气。红外气体分析仪包括红外能量检测器，样品池和红外能量源，其被设计为小并且消耗相对较小的电功率。红外能量检测器将接收的入射辐射转换成代表所接收的入射辐射的至少一个电信号，并且优选地直接安装在包含处理由红外能量检测器提供的电检测信号的信号处理电路的印刷电路板上。红外能量检测器还在其检测侧具有第一红外透射窗口，入射辐射穿过该第一红外透射窗口用于检测。样品池优选安装在红外能量检测器的检测侧，并接收来自患者的至少一部分基本上气态的流动流，并将接收到的部分引导到共享红外能量的第一红外透射窗口的检测体积检测器在其一侧。然后将红外能量源安装在与红外能量检测器相对的样品池侧，使得发射的红外能量通过由红外能量源共享的第二红外透射窗口和与红外能量相反的一侧探测器。经过第二红外透射窗后，来自红外光源的红外能量通过检测体积，由气体成分吸收，然后穿过第一个红外透射窗，由红外能量检测器进行检测。然后从所得到的吸收信号计算气体成分的浓度。

75. 发明授权

US5282473A Sidestream infrared gas analyzer requiring small sample volumes 失效
标题翻译：侧流红外线气体分析仪需要较小的样品量
公开(公告)号：US5282473A
公开(公告)日：1994-02-01
申请号：US976145
申请日：1992-11-10
申请人： James R. Braig , Daniel S. Goldberger
发明人： James R. Braig , Daniel S. Goldberger
IPC分类号： A61B5/083 , A61B5/097 , G01N21/05 , G01N21/35
CPC分类号： G01N21/05 , A61B5/083 , A61B5/097 , G01N21/3504
摘要： An infrared gas analyzer implementing an optically stabilized detector in a sidestream configuration. In order to reduce the pneumatic sampling volume, an "optical funnel" or collimator is used to resize the optical aperture of a multi-channel optically stabilized detector without compromising signal strength. The smaller pneumatic volume is desirable in order to minimize the time required for a gas wavefront from the sample cell to traverse the optical aperture, thereby minimizing pneumatic response time. The geometry of the sample cell of the invention is also streamlined so that sharp corners or transitions which might induce turbulent gas flow are eliminated. The sample cell of the invention thus promotes smooth, laminar flow of aspirated respiratory gases through the optical aperture so as to preserve the temporal relationship of gas concentration wavefronts within the gas stream and to thereby allow the analyzer to exhibit a faster pneumatic response.
摘要翻译：实现侧流配置的光学稳定检测器的红外气体分析仪。为了降低气动采样体积，使用“光漏斗”或准直器来调整多通道光学稳定检测器的光学孔径，而不会影响信号强度。较小的气动体积是期望的，以便最小化来自样品池的气体波前穿过光学孔所需的时间，从而最小化气动响应时间。本发明的样品池的几何形状也是流线型的，从而消除了可能引起湍流气流的尖角或过渡。因此，本发明的样品池通过光学孔促进吸入的呼吸气体的平滑的层流，从而保持气体流中的气体浓度波前的时间关系，从而允许分析仪表现出更快的气动响应。

76. 发明授权

US5281817A Method of selecting an optical filter for a shutterless optically stabilized capnograph 失效
标题翻译：选择无光闸光学稳定捕集仪的滤光片的方法
公开(公告)号：US5281817A
公开(公告)日：1994-01-25
申请号：US782991
申请日：1991-10-28
申请人： Mark L. Yelderman , James R. Braig , Daniel S. Goldberger
发明人： Mark L. Yelderman , James R. Braig , Daniel S. Goldberger
IPC分类号： A61B5/083 , G01J1/24 , G01J5/12 , G01N21/31 , G01N21/35 , G01N21/61 , G01J3/51
CPC分类号： G01N21/3504 , A61B5/083 , G01J1/24 , G01J5/12 , G01N2021/3166 , G01N2201/126
摘要： Methods and apparatus for constructing optically stabilized, shutterless infrared capnographs are disclosed. The capnographs of the present invention provide the absolute concentration of the constituents of the respiratory airstream of a patient, without the thermal drift problems normally associated with thermopile detectors, thereby providing a device with a high degree of accuracy. The present invention eliminates the need for a mechanical shutter to modulate the incident infrared beam and the need for a modulated source, thereby increasing the reliability and response time of the devices disclosed. Capnographs which are substantially unaffected by changes in the ambient temperature at which they operate are provided by connecting pairs of optically filtered thermopiles in series and processing the resulting differential pair. In addition, techniques are provided for selecting overlapping optical filters for use with thermopiles with a minimum level of cross-talk. A processing technique is also given which allows the concentrations of two or more airstream constituents to be separately quantified even when such overlapping optical filters are used.
摘要翻译：公开了用于构造光学稳定的无闸门红外捕集仪的方法和装置。本发明的血氧监护仪提供了患者的呼吸气流的成分的绝对浓度，而没有通常与热电堆检测器相关的热漂移问题，从而提供高精度的装置。本发明不需要机械快门来调制入射的红外光束和调制源的需要，从而增加所公开的设备的可靠性和响应时间。基本上不受其工作环境温度变化影响的测井仪通过串联连接成对的光学过滤的热电堆并处理所得的差分对来提供。另外，提供了用于选择具有最低水平的串扰的热电堆使用的重叠光学滤波器的技术。还给出了即使使用这种重叠的光学滤波器也允许分开量化两种或更多种气流成分的浓度的处理技术。

77. 发明授权

US5129401A Method for distinguishing respiratory events in a gas analyzer 失效
标题翻译：用于区分气体分析仪中呼吸事件的方法
公开(公告)号：US5129401A
公开(公告)日：1992-07-14
申请号：US458974
申请日：1990-01-25
申请人： James E. Corenman , Daniel S. Goldberger , Edward M. Richards , Emil P. Rojas , James R. Braig , David A. Gallup
发明人： James E. Corenman , Daniel S. Goldberger , Edward M. Richards , Emil P. Rojas , James R. Braig , David A. Gallup
IPC分类号： A61B5/083 , G01N21/31 , G01N21/35
CPC分类号： A61B5/083 , G01N21/3504 , G01N2021/3129 , G01N2201/121
摘要： A gas analyzer system and method for detecting and displaying information of gases in a respiratory gas stream, comprising an optical bench including a gas pathway for the flow of a gas stream through the optical bench, a flow shaping inlet at the entrance to the optical bench's gas pathway, two infrared detection channel assemblies for measuring the partial pressures of the gases in the respiratory gas stream, a pressure sensor for measuring the pressure within the gas pathway, a temperature sensor for measuring the temperature within the optical bench, and a flow rate sensor for measuring the gas flow rate through the gas pathway, circuitry for processing the detected partial pressures of the gases and the measured values for pressure, temperature, and flow rate, and for providing output signals indicative of processed measured values, the detected partial pressures of the gasses, and characterization information with respect to the optical bench components; analog input circuitry for processing the signals output from the optical bench for input to analog processing circuitry; analog processing circuitry for processing and correcting at least the detected partial pressures of the gases signals for collision broadening, temperature, pressure in the gas pathway, barometric pressure, cross-correction, and characterization of the optical bench components, and providing output signals indicative of the corrected partial pressures of the gases to display processing circuitry; display processing circuitry for processing the signals for display of at least the corrected partial pressure of one gas on a cathode ray tube.
摘要翻译：一种用于检测和显示呼吸气流中的气体信息的气体分析仪系统和方法，包括一个光学台，包括用于通过光学台的气流流动的气体通道，在光学台的入口处的流动成形入口气体通道，用于测量呼吸气流中的气体的分压的两个红外检测通道组件，用于测量气体通道内的压力的压力传感器，用于测量光学平台内的温度的温度传感器，以及流速用于测量通过气体通路的气体流量的传感器，用于处理检测到的气体分压的电路和用于压力，温度和流速的测量值，以及用于提供指示经处理的测量值的输出信号，检测到的分压的气体，以及关于光学台架部件的表征信息; 模拟输入电路，用于处理从光学平台输出的用于输入到模拟处理电路的信号; 模拟处理电路，用于处理和校正至少检测到的气体信号的分压，用于碰撞扩张，气体通路中的温度，压力，气压，交叉校正和光学台部件的表征，以及提供指示校正的显示处理电路的气体分压; 显示处理电路，用于处理用于显示至少阴极射线管上的一种气体的校正分压的信号。

78. 发明授权

US4907166A Multichannel gas analyzer and method of use 失效
标题翻译：多通道气体分析仪及其使用方法
公开(公告)号：US4907166A
公开(公告)日：1990-03-06
申请号：US101931
申请日：1987-09-25
申请人： James E. Corenman , Daniel S. Goldberger , Edward M. Richards , Emil P. Rojas , James R. Braig , David A. Gallup
发明人： James E. Corenman , Daniel S. Goldberger , Edward M. Richards , Emil P. Rojas , James R. Braig , David A. Gallup
IPC分类号： A61B5/08 , A61B5/083 , G01N21/31 , G01N21/35 , G01N21/61 , G06F15/42
CPC分类号： A61B5/083 , G01N21/3504 , G01N2021/3129 , G01N21/61 , G01N2201/121
摘要： An improved gas analyzer system (FIG. 1) and method of use for detecting and displaying the partial pressures of certain constituent gases in a respiratory gas stream, the system comprising an optical bench (111) through which a respiratory gas flows and in which measurements of the gas are taken; analog input circuits (122) for receiving signals output from the optical bench (111) through which a respiratory gas flows and in which measurements of the gas are taken; analog processing circuits (124) for processing signals output from the analog input circuits (122); display processing circuits (128) for processing the signals output from the analog processing circuits (124) and other system circuitry; pixel logic circuits/analog outputs (130) for processing signals output from the display processing circuitry (128) and providing analog output ports; a five button panel (148), an alarm/knob board (144), and a speaker driver (152) for operator interface and activation of audible and visual alarms; a CRT driver for driving a CRT; and a power supply (158) for powering the system.

79. 发明授权

US6091504A Method and apparatus for measuring gas concentration using a semiconductor laser 失效
标题翻译：使用半导体激光器测量气体浓度的方法和装置
公开(公告)号：US6091504A
公开(公告)日：2000-07-18
申请号：US82662
申请日：1998-05-21
申请人： Stephen D. Walker , Robert A. Nichols , William A. Curnan , Sophat Svai , James R. Braig , Daniel S. Goldberger
发明人： Stephen D. Walker , Robert A. Nichols , William A. Curnan , Sophat Svai , James R. Braig , Daniel S. Goldberger
IPC分类号： G01N21/39 , G01N21/00
CPC分类号： G01N21/39
摘要： A system and method for determining the concentration of an analyte such as oxygen in an unknown gas sample. A Vertical Cavity Surface Emitting Laser (VCSEL) is used as a variable wavelength light source which is "swept" through a wavelength range by varying the drive signal applied thereto. Quantitative spectroscopic analysis of the unknown gas sample is performed without the requirement of feedback circuitry for tuning the light source to the characteristic frequency of an analyte. Instead, the VCSEL is repeatedly "swept" through a range of frequencies determined by the drive signal, and the absorption is measured by the detector. The absorption lines do not always occur at the same place but instead move along around during the sweep based on the temperature and baseline current. The absorption at a particular wavelength may be determined by overlaying the drive signal and its timing information over the detected absorption signal.
摘要翻译：用于确定未知气体样品中分析物如氧的浓度的系统和方法。垂直腔面发射激光器（VCSEL）被用作通过改变施加到其上的驱动信号通过波长范围“扫过”的可变波长光源。进行未知气体样品的定量光谱分析，而不需要用于将光源调谐到分析物的特征频率的反馈电路。相反，VCSEL在由驱动信号确定的频率范围内被重复扫描，并且由检测器测量吸收。吸收线并不总是发生在相同的位置，而是基于温度和基线电流在扫描过程中沿着周围移动。可以通过将驱动信号及其定时信息覆盖在检测到的吸收信号上来确定特定波长处的吸收。

80. 发明授权

US5247185A Regulated infrared source 失效
标题翻译：调节红外源
公开(公告)号：US5247185A
公开(公告)日：1993-09-21
申请号：US782990
申请日：1991-10-28
申请人： Roger O. Herrera , James R. Braig , Daniel S. Goldberger
发明人： Roger O. Herrera , James R. Braig , Daniel S. Goldberger
IPC分类号： G01J5/02 , G01J3/10 , G01J5/00 , G01N21/01 , G01N21/35 , G05D23/24 , H05B3/46
CPC分类号： G05D23/24 , G01J3/108 , H05B3/46 , G01N21/3504 , G01N2201/069
摘要： An infrared source which provides a miniature, highly stable and efficient source of infrared energy for use with infrared detectors and the like. The infrared source of the invention incorporates a platinum resistance temperature detector (RTD) which is integrated with the heater element to provide a means of electronic servo control of the heater temperature. The heater element and the RTD are tightly coupled thermally to provide accurate, continuous tracking and control of the heater temperature. The infrared source design provides excellent infrared energy output with less than one watt input power to the heater.
摘要翻译：提供用于红外探测器等的微型，高度稳定和高效的红外能量源的红外源。本发明的红外光源包括与加热器元件集成的铂电阻温度检测器（RTD），以提供加热器温度的电子伺服控制装置。加热器元件和RTD紧密耦合，以提供对加热器温度的精确，连续的跟踪和控制。红外源设计为加热器提供了不到一瓦特输入功率的出色的红外能量输出。

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