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71. 发明申请

US20120046557A1 FLUID TITRATION SYSTEM 有权
标题翻译：流体搅拌系统
公开(公告)号：US20120046557A1
公开(公告)日：2012-02-23
申请号：US13287060
申请日：2011-11-01
申请人： Massi E. Kiani
发明人： Massi E. Kiani
IPC分类号： A61B5/02
CPC分类号： A61B5/6826 , A61B5/0295 , A61B5/14551 , A61B5/6838 , A61M5/142 , A61M2205/3306 , A61M2205/3313
摘要： A fluid titration system has an optical sensor, a physiological monitor, a titration controller and an infusion device. The optical sensor transmits multiple wavelengths of light into a tissue site of a person and detects the optical radiation after attenuation by pulsatile blood flowing within the tissue site. The physiological monitor receives a resulting sensor signal and derives a plethysmograph that corresponds to the pulsatile blood flow. The monitor also calculates a plethysmograph variability measure that is responsive to changes in perfusion at the tissue site. A titration controller generates a fluid control output according to the variability measure. The infusion device administers a liquid solution via an intravenous (IV) connection to the person according to the fluid control output so as to regulate at least one of a fluid flow start, rate and stop.
摘要翻译：液体滴定系统具有光学传感器，生理监测器，滴定控制器和输注装置。光学传感器将多个波长的光发射到人的组织部位，并通过在组织部位内流动的脉动血液来检测衰减后的光辐射。生理监测器接收所得到的传感器信号并导出对应于脉动血流量的体积描记器。显示器还计算出对组织部位灌注变化有反应的体积描记器变异性测量。滴定控制器根据可变性度量产生流体控制输出。输注装置通过根据流体控制输出的人静脉内（IV）连接来施用液体溶液，以调节流体流动开始，速率和停止中的至少一个。

72. 发明授权

US07976472B2 Noninvasive hypovolemia monitor 有权
标题翻译：无创性低血容量监测仪
公开(公告)号：US07976472B2
公开(公告)日：2011-07-12
申请号：US11221411
申请日：2005-09-06
申请人： Massi E. Kiani
发明人： Massi E. Kiani
IPC分类号： A61B5/02
CPC分类号： A61B5/02416 , A61B5/0059 , A61B5/02042 , A61B5/0816 , A61B5/1455
摘要： A hypovolemia monitor comprises a plethysmograph input responsive to light intensity after absorption by fleshy tissue. A measurement of respiration-induced variation in the input is made. The measurement is normalized and converted into a hypovolemia parameter. An audible or visual indication of hypovolemia is provided, based upon the hypovolemia parameter.
摘要翻译：低血容量监测器包括响应于肉质组织吸收后的光强度的体积描记器输入。进行呼吸引起的输入变化的测量。测量被归一化并转换为低血容量参数。根据血容量不足参数提供血容量不足的视觉或视觉指征。

73. 发明申请

US20090076462A1 FLUID TITRATION SYSTEM 有权
标题翻译：流体搅拌系统
公开(公告)号：US20090076462A1
公开(公告)日：2009-03-19
申请号：US12208998
申请日：2008-09-11
申请人： Massi E. Kiani
发明人： Massi E. Kiani
IPC分类号： A61M5/00 , A61B5/00
CPC分类号： A61B5/6826 , A61B5/0295 , A61B5/14551 , A61B5/6838 , A61M5/142 , A61M2205/3306 , A61M2205/3313
摘要： A fluid titration system has an optical sensor, a physiological monitor, a titration controller and an infusion device. The optical sensor transmits multiple wavelengths of light into a tissue site of a person and detects the optical radiation after attenuation by pulsatile blood flowing within the tissue site. The physiological monitor receives a resulting sensor signal and derives a plethysmograph that corresponds to the pulsatile blood flow. The monitor also calculates a plethysmograph variability measure that is responsive to changes in perfusion at the tissue site. A titration controller generates a fluid control output according to the variability measure. The infusion device administers a liquid solution via an intravenous (IV) connection to the person according to the fluid control output so as to regulate at least one of a fluid flow start, rate and stop.
摘要翻译：液体滴定系统具有光学传感器，生理监测器，滴定控制器和输注装置。光学传感器将多个波长的光发射到人的组织部位，并通过在组织部位内流动的脉动血液来检测衰减后的光辐射。生理监测器接收所得到的传感器信号并导出对应于脉动血流量的体积描记器。显示器还计算出对组织部位灌注变化有反应的体积描记器变异性测量。滴定控制器根据可变性度量产生流体控制输出。输注装置通过根据流体控制输出的人静脉内（IV）连接来施用液体溶液，以调节流体流动开始，速率和停止中的至少一个。

74. 发明授权

US06771994B2 Pulse oximeter probe-off detection system 有权
标题翻译：脉搏血氧仪探头检测系统
公开(公告)号：US06771994B2
公开(公告)日：2004-08-03
申请号：US10374303
申请日：2003-02-24
申请人： Massi E. Kiani , Mohamed K. Diab
发明人： Massi E. Kiani , Mohamed K. Diab
IPC分类号： A61B500
CPC分类号： A61B5/6843 , A61B5/14552
摘要： The present invention provides a number of improvements that can be incorporated into a pulse oximeter probe to detect when a probe has become dislodged from a patient and/or to prevent a probe-off condition. A probe-off condition occurs when the optical probe becomes partially or completely dislodged from the patient, but continues to detect an AC signal within the operating region of the pulse oximeter. In one aspect, the present invention provides electrical contacts that contact the skin of a patient when the probe is properly attached. In another aspect, the present invention provides a number of louvers placed in front of the sensor's photodetector to filter out oblique light rays that do not originate from a point in front of the detector. Accordingly, if the emitter and photodetector are not properly aligned, the photodetector will not produce a signal within the valid operating range of the pulse oximeter. In accordance with a method of the present invention the pulse oximeter can sound an alarm or display a warning if it determines that the probe is not properly attached to the patient.
摘要翻译：本发明提供了许多可以结合到脉搏血氧计探针中以检测探针什么时候已经从患者脱离和/或防止探针状态的改进。当光学探针从患者部分或完全脱落而继续检测到在脉搏血氧计的操作区域内的AC信号时，会发生探测条件。一方面，本发明提供了当探针适当地附接时与患者的皮肤接触的电触点。在另一方面，本发明提供了放置在传感器的光电检测器前方的多个百叶窗，以过滤出不是源于检测器前面的点的倾斜光线。因此，如果发射器和光电检测器未正确对准，则光电检测器将不会在脉冲血氧计的有效工作范围内产生信号。根据本发明的方法，如果脉搏血氧计确定探头未正确地附接到患者，则脉搏血氧计可以发出警报或显示警告。

75. 再颁专利

USRE38476E1 Signal processing apparatus 有权
标题翻译：信号处理装置
公开(公告)号：USRE38476E1
公开(公告)日：2004-03-30
申请号：US10185804
申请日：2002-06-27
申请人： Mohamed K. Diab , Massi E. Kiani , Ibrahim M. Elfadel , Rex J. McCarthy , Walter M. Weber , Robert A. Smith
发明人： Mohamed K. Diab , Massi E. Kiani , Ibrahim M. Elfadel , Rex J. McCarthy , Walter M. Weber , Robert A. Smith
IPC分类号： A61B500
CPC分类号： H04B1/123 , A61B5/021 , A61B5/02154 , A61B5/024 , A61B5/029 , A61B5/0402 , A61B5/0476 , A61B5/0816 , A61B5/14532 , A61B5/14546 , A61B5/14551 , A61B5/4821 , A61B5/7214 , A61B5/7253 , A61B5/7257 , A61B6/00 , A61B8/00 , A61B8/5276 , G06K9/0051
摘要： The present invention involves method and apparatus for analyzing two measured signals that are modeled as containing primary and secondary portions. Coefficients relate the two signals according to a model defined in accordance with the present invention. In one embodiment, the present invention involves utilizing a transformation which evaluates a plurality of possible signal coefficients in order to find appropriate coefficients. Alternatively, the present invention involves using statistical functions or Fourier transform and windowing techniques to determine the coefficients relating to two measured signals. Use of this invention is described in particular detail with respect to blood oximetry measurements.

76. 发明授权

US6157850A Signal processing apparatus 失效
公开(公告)号：US6157850A
公开(公告)日：2000-12-05
申请号：US859837
申请日：1997-05-16
申请人： Mohamed K. Diab , Massi E. Kiani , Ibrahim M. Elfadel , Rex J. McCarthy , Walter M. Weber , Robert A. Smith
发明人： Mohamed K. Diab , Massi E. Kiani , Ibrahim M. Elfadel , Rex J. McCarthy , Walter M. Weber , Robert A. Smith
IPC分类号： A61B5/0245 , A61B5/00 , A61B5/02 , A61B5/0215 , A61B5/145 , A61B5/1455 , A61B5/1464 , A61B6/00 , A61B8/00 , G06F17/00 , G06F19/00 , H04B1/12 , H04B3/46 , H04B17/00
CPC分类号： H04B1/123 , A61B5/14546 , A61B5/14551 , A61B5/4821 , A61B5/7214 , A61B5/7253 , A61B8/5276 , G06K9/0051 , A61B5/021 , A61B5/02154 , A61B5/024 , A61B5/029 , A61B5/0402 , A61B5/0476 , A61B5/0816 , A61B5/14532 , A61B5/7257 , A61B6/00 , A61B8/00
摘要： The present invention involves method and apparatus for analyzing two measured signals that are modeled as containing primary and secondary portions. Coefficients relate the two signals according to a model defined in accordance with the present invention. In one embodiment, the present invention involves utilizing a transformation which evaluates a plurality of possible signal coefficients in order to find appropriate coefficients. Alternatively, the present invention involves using statistical functions or Fourier transform and windowing techniques to determine the coefficients relating to two measured signals. Use of this invention is described in particular detail with respect to blood oximetry measurements.

77. 发明授权

US5995855A Pulse oximetry sensor adapter 失效
公开(公告)号：US5995855A
公开(公告)日：1999-11-30
申请号：US21957
申请日：1998-02-11
申请人： Massi E. Kiani , Robert A. Smith , David R. Tobler
发明人： Massi E. Kiani , Robert A. Smith , David R. Tobler
IPC分类号： A61B5/00
CPC分类号： A61B5/14551 , A61B5/14552 , A61B2562/222 , Y10S439/909
摘要： An adapter allows the interconnection of a sensor originating from one manufacturer to be coupled with conventionally incompatible monitors originating from other manufacturers to form a properly functioning pulse oximetry system. The adapter matches a sensor driver in a monitor to the current requirements and light source configuration of a sensor. The adapter also matches a sensor's light detector signal level to the dynamic range requirements of a monitor preamplifier. Further, the adapter provides compatible sensor calibration, sensor type and security information to a monitor. The adapter may have a self-contained power source or it may derive power from the monitor, allowing both passive and active adapter components. The adapter is particular suited as an adapter cable, replacing a conventional patient cable or sensor cable as the interconnection between a sensor to a monitor in a pulse oximetry system.

78. 发明授权

US09333316B2 Drug administration controller 有权
标题翻译：药物管理控制员
公开(公告)号：US09333316B2
公开(公告)日：2016-05-10
申请号：US13475136
申请日：2012-05-18
申请人： Massi E. Kiani
发明人： Massi E. Kiani
IPC分类号： A61M31/00 , A61M16/12 , A61M5/172
CPC分类号： A61M5/1723 , A61M5/142 , A61M16/0057 , A61M16/12 , A61M2202/0208 , A61M2202/0233 , A61M2202/0241 , A61M2205/18 , A61M2205/3313 , A61M2205/3375 , A61M2205/3561 , A61M2205/3592 , A61M2205/502 , A61M2230/005 , A61M2230/04 , A61M2230/10 , A61M2230/204 , A61M2230/205 , A61M2230/207 , A61M2230/30 , A61M2230/42 , A61M2230/432 , A61M2230/50
摘要： A drug administration controller has a sensor that generates a sensor signal to a physiological measurement device, which measures a physiological parameter in response. A control output responsive to the physiological parameter or a metric derived from the physiological parameter causes a drug administration device to affect the treatment of a person, such as by initiating, pausing, halting or adjusting the dosage of drugs administered to the person.
摘要翻译：药物管理控制器具有向生理测量装置产生传感器信号的传感器，其响应于测量生理参数。响应于生理参数或来自生理参数的指标的控制输出导致药物施用装置影响人的治疗，例如通过引发，暂停，停止或调节施用于该人的药物的剂量。

79. 发明授权

US08182443B1 Drug administration controller 有权
标题翻译：药物管理控制员
公开(公告)号：US08182443B1
公开(公告)日：2012-05-22
申请号：US11654904
申请日：2007-01-17
申请人： Massi E. Kiani
发明人： Massi E. Kiani
IPC分类号： A61M1/00 , A61M31/00 , A61M37/00
CPC分类号： A61M5/1723 , A61M5/142 , A61M16/0057 , A61M16/12 , A61M2202/0208 , A61M2202/0233 , A61M2202/0241 , A61M2205/18 , A61M2205/3313 , A61M2205/3375 , A61M2205/3561 , A61M2205/3592 , A61M2205/502 , A61M2230/005 , A61M2230/04 , A61M2230/10 , A61M2230/204 , A61M2230/205 , A61M2230/207 , A61M2230/30 , A61M2230/42 , A61M2230/432 , A61M2230/50
摘要： A drug administration controller has a sensor that generates a sensor signal to a physiological measurement device, which measures a physiological parameter in response. A control output responsive to the physiological parameter or a metric derived from the physiological parameter causes a drug administration device to affect the treatment of a person, such as by initiating, pausing, halting or adjusting the dosage of drugs administered to the person.
摘要翻译：药物管理控制器具有向生理测量装置产生传感器信号的传感器，其响应于测量生理参数。响应于生理参数或来自生理参数的指标的控制输出导致药物施用装置影响人的治疗，例如通过引发，暂停，停止或调节施用于该人的药物的剂量。

80. 发明授权

US07990382B2 Virtual display 有权
标题翻译：虚拟显示
公开(公告)号：US07990382B2
公开(公告)日：2011-08-02
申请号：US11648972
申请日：2007-01-03
申请人： Massi E. Kiani
发明人： Massi E. Kiani
IPC分类号： G06T17/00
CPC分类号： G06T11/20
摘要： Display objects are defined that are capable of visually indicating physiological measurements and physiological monitor status. A virtual display utilizing these display objects is characterized by selecting those display objects corresponding to one or more particular physiological parameters, organizing the selected display objects within a virtual display area corresponding to at least a portion of a physical display, and associating data objects corresponding to the one or more physiological parameters with the selected display objects.
摘要翻译：定义显示对象，其能够可视地指示生理测量和生理监视状态。使用这些显示对象的虚拟显示器的特征在于，选择与一个或多个特定生理参数对应的那些显示对象，在对应于物理显示器的至少一部分的虚拟显示区域内组织所选择的显示对象，并且将对应于所述一个或多个生理参数与所选择的显示对象。

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