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71. 发明授权

US4861792A Hydantoin derivatives for treating complications of diabetes 失效
标题翻译：用于治疗糖尿病并发症的乙内酰脲衍生物
公开(公告)号：US4861792A
公开(公告)日：1989-08-29
申请号：US90729
申请日：1987-08-28
申请人： Masayasu Kurono , Yasuaki Kondo , Takuji Yamaguchi , Kenji Miura , Toshinao Usui , Naofumi Terada , Kyoichi Asano , Kuniharu Mizuno , Akira Matsubara , Noriaki Kato , Kiichi Sawai , Ryoichi Unno , Hiroshi Ozawa , Masato Fukushima
发明人： Masayasu Kurono , Yasuaki Kondo , Takuji Yamaguchi , Kenji Miura , Toshinao Usui , Naofumi Terada , Kyoichi Asano , Kuniharu Mizuno , Akira Matsubara , Noriaki Kato , Kiichi Sawai , Ryoichi Unno , Hiroshi Ozawa , Masato Fukushima
IPC分类号： C07D311/24 , C07D491/10 , C07D491/107 , C07D495/10
CPC分类号： C07D491/10 , C07D311/24 , C07D495/10
摘要： Hydantoin derivatives and salts thereof, intermediates therefor, process for the preparation thereof, and medicines containing the derivative, wherein said derivatives have the formula ##STR1## wherein one of V and W is hydrogen and the other is a halogenomethyl group, 1H-tetrazol-5-yl radical, --COOR group,in which R is hydrogen atom, an alkyl group, --(CH.sub.2 CH.sub.2 O)nCH.sub.3 group (n is an integer of 1 to 113) or substituted phenyl, ##STR2## in which R.sub.1 and R.sub.2 are same or different independently, each is hydrogen atom, an alkyl group, substituted phenyl or --(CH.sub.2 CH.sub.2 O)nCH.sub.3 group (n has the meaning as referred to) or R.sub.1 may form a heterocyclic ring together with R.sub.2 and nitrogen or oxygen atom, ##STR3## in which R.sub.2 and R.sub.4 are same or different independently and each is hydrogen atom or an alkyl group,X is oxygen or sulfur atom, and Y and Z are same or different independently and each is hydrogen atom, a halogen atom, alkyl group, alkoxy group, alkylmercapto group, nitro radical or --NHR.sub.5 group, in which R.sub.5 is hydrogen atom or an acyl group.The derivatives and salts thereof are useful for the treatment of complications of diabetes.

72. 发明授权

US4771008A Method for quantitative analysis of thyroid hormone 失效
标题翻译：甲状腺激素定量分析方法
公开(公告)号：US4771008A
公开(公告)日：1988-09-13
申请号：US36143
申请日：1987-04-06
申请人： Kenji Miura , Yukio Yasuda
发明人： Kenji Miura , Yukio Yasuda
IPC分类号： G01N33/53 , G01N33/531 , G01N33/68 , G01N33/74 , G01N33/78
CPC分类号： G01N33/74 , G01N33/53 , G01N33/78 , Y10S436/825
摘要： A method for quantitative analysis of low molecular weight components which are contained in a protein-containing liquid sample originating from body fluids and are capable of binding to said protein, characterized by incorporating into the liquid sample a compound having the formula (I):X--(Y).sub.p --SO.sub.3 M (I)in which M is hydrogen ion, an alkali metal ion, or ammonium ion; X is a straight or branched alkyl, alkenyl, fluorinated alkyl, or fluorinated alkenyl group containing at least 6 carbon atoms, Y is a divilent organic residue; and p is 0 r 1. The compound represented by formula (I) liberates thyroid hormone from bound protein to facilitate analysis.
摘要翻译：一种用于定量分析含有源自体液的含蛋白质的液体样品中能够结合所述蛋白质的低分子量组分的方法，其特征在于向液体样品中加入具有式（I）的化合物：X - （Y）p-SO 3 M（I）其中M是氢离子，碱金属离子或铵离子; X是含有至少6个碳原子的直链或支链烷基，烯基，氟化烷基或氟化烯基，Y是疏水有机残基; 并且p为0r 1.由式（I）表示的化合物从结合的蛋白质释放甲状腺激素以促进分析。

73. 发明授权

US4672410A Semiconductor memory device with trench surrounding each memory cell 失效
标题翻译：具有围绕每个存储单元的沟槽的半导体存储器件
公开(公告)号：US4672410A
公开(公告)日：1987-06-09
申请号：US753283
申请日：1985-07-09
申请人： Kenji Miura , Shigeru Nakajima , Kazushige Minegishi , Takashi Morie , Toshifumi Somatani
发明人： Kenji Miura , Shigeru Nakajima , Kazushige Minegishi , Takashi Morie , Toshifumi Somatani
IPC分类号： H01L21/20 , H01L21/225 , H01L21/8242 , H01L27/10 , H01L27/108 , H01L29/78 , H01L29/94 , H01L27/02 , H01L29/04 , H01L29/06
CPC分类号： H01L27/10864 , H01L21/2257 , H01L27/10841 , H01L29/7827 , H01L29/945
摘要： A semiconductor device has memory cells respectively located at intersections of bit and word lines arranged in a matrix form, each of the memory cells being constituted by a single insulated gate transistor and a single capacitor. One memory cell is formed in an element formation region defined by each of trenches arranged in a matrix form. The capacitor has an insulating film formed along part of a side wall surface of a trench formed in at least a direction of thickness of a semiconductor substrate and a conductive layer formed along the insulating film. The transistor has a gate insulating film adjacent to the capacitor and formed along a remaining portion of the side wall surface of the trench, a gate electrode formed along the gate insulating film, and a diffusion region formed in a major surface of the semiconductor substrate which is adjacent to the gate insulating film. The semicondcutor memory device further has an isolation region between two adjacent ones of the memory cells along two adjacent ones of the bit or word lines. A method of manufacturing the semiconductor is also proposed.
摘要翻译：半导体器件具有分别位于以矩阵形式布置的位和字线的交点处的存储器单元，每个存储器单元由单个绝缘栅晶体管和单个电容器构成。一个存储单元形成在由以矩阵形式布置的每个沟槽限定的元件形成区域中。电容器具有沿至少沿着半导体衬底的厚度方向形成的沟槽的侧壁表面的一部分和沿绝缘膜形成的导电层形成的绝缘膜。晶体管具有与电容器相邻的栅极绝缘膜，沿着沟槽的侧壁表面的剩余部分形成，沿着栅极绝缘膜形成的栅电极和形成在半导体衬底的主表面中的扩散区域与栅极绝缘膜相邻。半切割器存储器件还沿着位或字线中的两个相邻的存储器单元中的两个相邻存储单元之间具有隔离区。还提出了制造半导体的方法。

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