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    • 77. 发明授权
    • Cell-permeable endostatin recombinant protein, a polynucleotide encoding the same, and an anti-cancer preparation containing the same as an active component
    • 细胞可渗透的内皮抑素重组蛋白,编码该多核苷酸的多核苷酸以及含有与活性成分相同的抗癌制剂
    • US08586544B2
    • 2013-11-19
    • US12936334
    • 2009-04-03
    • Daewoong JoJong Min LeeKyoungho ParkMinh Tam Duong
    • Daewoong JoJong Min LeeKyoungho ParkMinh Tam Duong
    • A61K45/06
    • C07K14/78A61K38/17C07K2319/01
    • The present invention relates to a cell-permeable endostatin recombinant protein in which a macromolecule transduction domain (MTD) is fused to an angiogenesis inhibitor (angiogenesis inhibitor) endostatin; a polynucleotide encoding the cell-permeable endostatin recombinant protein; an expression vector for the cell-permeable endostatin recombinant protein; and a pharmacological composition for an anti-cancer preparation with improved inhibitory activity against angiogenesis in cancer, which contains the cell-permeable endostatin recombinant protein as an active component. The cell-permeable endostatin recombinant protein according to the present invention can block the formation of microvessels and inhibit the migration, proliferation, penetration, tube formation and the like of vascular endothelial cells present in tumor tissue by introducing the angiogenesis inhibitor endostatin into the cell with high efficiency, and it exhibits outstanding anti-cancer activity and so can be used as an anti-cancer drug against various cancers.
    • 本发明涉及一种细胞可渗透的内皮抑素重组蛋白,其中大分子转导结构域(MTD)与血管生成抑制剂(血管发生抑制剂)内皮抑制素融合; 编码细胞可渗透内皮抑素重组蛋白的多核苷酸; 用于细胞渗透性内皮抑素重组蛋白的表达载体; 以及含有对细胞可渗透内皮抑素重组蛋白作为活性成分的癌症中血管生成抑制活性改善的抗癌剂的药理学组合物。 根据本发明的细胞可渗透的内皮抑素重组蛋白可以通过将血管生成抑制剂内皮抑制素引入细胞中来阻断微血管的形成并抑制存在于肿瘤组织中的血管内皮细胞的迁移,增殖,穿透,管形成等 效率高,具有突出的抗癌活性,可作为抗癌药物用于各种癌症。
    • 78. 发明授权
    • System for handling scheduled lending and self-returning of articles to which RFID tags are attached
    • 用于处理附着RFID标签的物品的定期贷款和自行退回的系统
    • US08527286B2
    • 2013-09-03
    • US11854191
    • 2007-09-12
    • Jong Min LeeGeon Hee HanHee Sang Kim
    • Jong Min LeeGeon Hee HanHee Sang Kim
    • G06Q10/00
    • G06K17/00G06K2017/0074
    • Disclosed herein is a system for handling scheduled lending and self-returning of articles to which RFID tags are attached. The system includes a body. The body includes, on a front surface thereof, a display for displaying a method of using the system, handling processes, and processing results, a speaker, a receipt issuing unit, a manipulational information input unit, an external antenna for transmitting/receiving information to/from the RFID tags, and a plurality of article depositories having respective internal antennas for transmitting/receiving information to/from the RFID tags. The body includes, on the inside thereof, a reader for reading the information recorded in the RFID tags through the external antenna and the internal antennas, and a controller for comparing information, transmitted/received to/from the reader, with stored article management information, checking validity of deposit, lending, and returning of the articles, and operating locking units of the article depositories, the display, the speaker, and the receipt issuing unit.
    • 这里公开了一种用于处理RFID标签附着的物品的定期借贷和自返还的系统。 系统包括一个主体。 主体在其前表面上包括用于显示使用系统的方法,处理过程和处理结果的显示器,扬声器,接收发行单元,操纵信息输入单元,用于发送/接收信息的外部天线 RFID标签和/或来自RFID标签的多个物品托盘,以及具有用于向/从RFID标签发送/接收信息的相应内部天线的多个物品托盘。 身体内部包括用于通过外部天线和内部天线读取记录在RFID标签中的信息的读取器,以及用于将从读取器发送/接收的信息与存储的物品管理信息进行比较的控制器 检查物品的存款,借出和退还的有效性,以及文件存放处,显示器,扬声器和收据发行单元的操作锁定单元。
    • 79. 发明授权
    • Method of making bread
    • 制作面包的方法
    • US08383173B2
    • 2013-02-26
    • US12418493
    • 2009-04-03
    • Myoung Gu LeeByung Keon SonJong Min Lee
    • Myoung Gu LeeByung Keon SonJong Min Lee
    • A21D8/02
    • A21D6/001A21D8/02
    • A method of making bread is provided. The method includes a thermally treated dough making process of forming a thermally heated dough, a dough mixing process of mixing the thermally treated dough of the thermally treated dough making process with wheat flour, dried yeast, refined sugar, refined salt, whole milk powder, bread improver, processed butter, milk, egg, and water to form a dough mixture, and stirring the dough mixture, a deep-freezing process of dividing the dough mixture into equal-sized dough pieces and deep-freezing the divided dough pieces, a thawing process of thawing the deep-frozen dough pieces, a fermentation process of fermenting the thawed dough pieces, and a baking process of heating the fermented dough pieces.
    • 提供制作面包的方法。 该方法包括热处理的面团制作方法,其形成热加热面团,将经热处理的生面团的热处理面团与小麦粉,干酵母,精制糖,精制盐,全脂奶粉混合的面团混合过程, 面包改良剂,加工黄油,牛奶,鸡蛋和水,以形成面团混合物,并搅拌面团混合物,将生面团混合物分成相同尺寸的面团片并将其分层的深度冷冻的深冷工艺, 解冻深冻面团的解冻过程,发酵解冻的面团的发酵过程以及加热发酵的面团的烘烤过程。