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71. 发明授权

US08192478B2 System for improving cardiac function 有权
公开(公告)号：US08192478B2
公开(公告)日：2012-06-05
申请号：US12268346
申请日：2008-11-10
申请人： Alexander Khairkhahan , Hugh R. Sharkey , Serjan D. Nikolic
发明人： Alexander Khairkhahan , Hugh R. Sharkey , Serjan D. Nikolic
IPC分类号： A61F2/06 , A61M29/08
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00632 , A61B2017/00867 , A61B2017/0649 , A61B2017/12095
摘要： A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge.

72. 发明授权

US08187312B2 Method for treating intervertebral disc 有权
公开(公告)号：US08187312B2
公开(公告)日：2012-05-29
申请号：US11872470
申请日：2007-10-15
申请人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
发明人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
IPC分类号： A61F7/00 , A61B18/14
CPC分类号： A61B17/1671 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/320016 , A61B17/320068 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/08 , A61B18/082 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0133 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09 , A61N1/06 , A61N1/40 , A61N1/403
摘要： A device is described that may be positioned at a location in an intervertebral disc for diagnosis or treatment of the disc. Treatment may include, for example, applying energy or removing material, and may decrease intradiscal pressure. Radiofrequency energy may be applied. A percutaneous method of repairing a fissure in the annulus pulposus comprises placing an energy source adjacent to the fissure and providing sufficient energy to the fissure to raise the temperature to at least about 45-70° C. and for a sufficient time to cause the collagen to weld. An intervertebral fissure also can be treated by placing a catheter with a lumen adjacent to the fissure and injecting sealant into the fissure via the catheter, thereby sealing the fissure. An intervertebral fissure additionally can be treated by providing a catheter having a distal end, a proximal end, a longitudinal axis, and an intradiscal section at the catheter's distal end on which there is at least one functional element. The next step is applying a force longitudinally to the proximal of the catheter which is sufficient to advance the intradiscal section through the nucleus pulposus and around an inner wall of an annulus fibrosus, but which force is insufficient to puncture the annulus fibrosus. Next the functional element is positioned at a selected location of the disc by advancing or retracting the catheter and optionally twisting the proximal end of the catheter. Then the functional unit treats the annular fissure. Optionally, there is an additional step of adding a substance to seal the fissure. An externally guidable intervertebral disc apparatus also is disclosed.

73. 发明授权

US07862500B2 Multiple partitioning devices for heart treatment 有权
标题翻译：用于心脏治疗的多重分隔装置
公开(公告)号：US07862500B2
公开(公告)日：2011-01-04
申请号：US11151156
申请日：2005-06-10
申请人： Alexander Khairkhahan , Serjan D. Nikolic , Branislav Radovancevic , Hugh R. Sharkey
发明人： Alexander Khairkhahan , Serjan D. Nikolic , Branislav Radovancevic , Hugh R. Sharkey
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61B17/12022 , A61B17/12122 , A61B17/12168 , A61B17/12172 , A61B2017/0084 , A61B2017/12095
摘要： This invention is directed to a system and method for partitioning a patient's heart chamber into a productive portion and a non-productive portion which are particularly suitable for treating patients with congestive heart failure. The partitioning system has a plurality of partitioning devices with reinforced, expandable membranes which separate the productive and non-productive portions of the heart chamber. When deployed within the patient's heart chamber, the second partitioning device is off-set from the deployed first partitioning device to cover a region of the wall defining the patient's heart chamber which is not covered by the first partitioning device. The multiple partitioning devices may be independent from each other or may be interconnected, e.g. a tether or strand.
摘要翻译：本发明涉及一种用于将患者的心脏室分成生产部分和非生产性部分的系统和方法，其特别适用于治疗患有充血性心力衰竭的患者。分隔系统具有多个具有加强的可扩张膜的分隔装置，其分离心室的生产和非生产性部分。当部署在患者的心室内时，第二分隔装置从展开的第一分隔装置偏离，以覆盖限定不被第一分隔装置覆盖的患者心室的壁的区域。多个分割装置可以彼此独立，或者可以相互连接。系绳或股绳。

74. 发明授权

US07647123B2 Method for treating intervertebral discs 失效
标题翻译：治疗椎间盘的方法
公开(公告)号：US07647123B2
公开(公告)日：2010-01-12
申请号：US11930813
申请日：2007-10-31
申请人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le T. Le
发明人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le T. Le
IPC分类号： A61N1/06
CPC分类号： A61B17/1671 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/320016 , A61B17/320068 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/08 , A61B18/082 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0133 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09 , A61N1/06 , A61N1/40 , A61N1/403
摘要： An interverterbral fissure can be treated by providing a catheter having a distal end, a proximal end, a longitudinal axis, and an intradiscal section at the catheter's distal end on which there is at least one functional element. The next step is applying a force longitudinally to the proximal of the catheter which is sufficient to advance the intradiscal section through the nucleus pulposus and around an inner wall of an annulus fibrosus, but which force is insufficient to puncture the annulus fibrosus. Next the functional element is positioned at a selected location of the disc by advancing or retracting the catheter and optionally twisting the proximal end of the catheter. Then the functional unit treats the annular fissure. Optionally, there is an additional step of adding a substance to seal the fissure.
摘要翻译：可以通过在导管的远端提供具有远端，近端，纵向轴线和椎间盘内截面的导管来治疗椎间裂缝，在该导管的至少一个功能元件上。下一步是向导管的近端施加一个力，这足以使椎间盘内部分通过髓核并绕纤维环的内壁延伸，但是哪个力不足以刺穿纤维环。接下来，功能元件通过前进或缩回导管并且可选地扭转导管的近端来定位在盘的选定位置。然后，功能单元处理环形裂缝。任选地，存在添加物质以密封裂缝的附加步骤。

75. 发明申请

US20090062601A1 SYSTEM FOR IMPROVING CARDIAC FUNCTION 有权
标题翻译：改善心脏功能的系统
公开(公告)号：US20090062601A1
公开(公告)日：2009-03-05
申请号：US12268346
申请日：2008-11-10
申请人： Alexander Khairkhahan , Hugh R. Sharkey , Serjan D. Nikolic
发明人： Alexander Khairkhahan , Hugh R. Sharkey , Serjan D. Nikolic
IPC分类号： A61F2/00
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00632 , A61B2017/00867 , A61B2017/0649 , A61B2017/12095
摘要： A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge.
摘要翻译：提供了一种改善心脏功能的系统。具有至少一个锚固结构的可折叠和可扩张的框架附接到细长的操纵器并且在折叠时放置在导管中。将管插入心脏的左心室，其中框架从管中弹出并在左心室中扩张。细长机械手的运动导致锚固体穿透心脏肌肉和细长操纵器以释放框架。安装的框架最小化形成动脉瘤隆起的心脏的运动部分的影响。

76. 发明申请

US20090054868A1 Uterine Therapy Device and Method 有权
标题翻译：子宫疗法装置及方法
公开(公告)号：US20090054868A1
公开(公告)日：2009-02-26
申请号：US12197084
申请日：2008-08-22
申请人： Hugh R. Sharkey , Ramiro Reyes , Kurt D. Sparks
发明人： Hugh R. Sharkey , Ramiro Reyes , Kurt D. Sparks
IPC分类号： A61M31/00
CPC分类号： A61B18/04 , A61B2017/3425 , A61B2017/4216 , A61B2017/4225 , A61B2018/00005 , A61B2018/00285 , A61B2018/00559 , A61B2018/048
摘要： A method and system of providing therapy to a patient's uterus. The method includes the steps of inserting an access tool through a cervix and a cervical canal into the uterus; actively cooling the cervical canal; delivering vapor through the access tool lumen into the uterus; and condensing the vapor on tissue within the uterus. The system has an access tool with a lumen, the access tool being adapted to be inserted through a human cervical canal to place an opening of the lumen within a uterus when the access tool is inserted through the cervical canal; an active cooling mechanism adapted to cool the cervical canal, the active cooling mechanism having a coolant source; and a vapor delivery mechanism adapted to deliver condensable vapor through the access tool to the uterus, the condensable vapor being adapted to condense within the uterus.
摘要翻译：为患者子宫提供治疗的方法和系统。该方法包括将进入工具通过子宫颈和子宫颈管插入子宫的步骤; 积极冷却宫颈管; 通过进入工具内腔将蒸气输送到子宫中; 并将蒸气冷凝在子宫内的组织上。该系统具有内腔的进入工具，当进入工具插入通过子宫颈管道时，进入工具适于插入人宫颈管以将管腔的开口放置在子宫内; 主动冷却机构，其适于冷却颈管，主动冷却机构具有冷却剂源; 以及适于将可冷凝蒸气通过所述进入工具输送到子宫的蒸汽递送机构，所述可冷凝蒸气适于在子宫内冷凝。

77. 发明授权

US07481807B2 Radiofrequency arthroscopic ablation device 有权
标题翻译：射频关节镜消融装置
公开(公告)号：US07481807B2
公开(公告)日：2009-01-27
申请号：US10490979
申请日：2003-02-12
申请人： Katherine A. Knudsen , Duane W. Marion , Hugh R. Sharkey
发明人： Katherine A. Knudsen , Duane W. Marion , Hugh R. Sharkey
IPC分类号： A61B18/18
CPC分类号： A61B18/148 , A61B2018/00101 , A61B2018/162 , A61B2218/002
摘要： A surgical device includes an elongated shaft having first and second electrically isolated electrodes coupled to the shaft such that an exposed portion of the second electrode is disposed around only part of a circumference of the elongated shaft, and includes a portion that is spaced proximally from the first electrode. Another surgical device also includes an elongated shaft having first and second electrically isolated electrodes coupled to the shaft, wherein the shaft includes a first side, and exposed surfaces of the first and second electrodes are side-facing toward the first side. Various embodiments of a “cool back” are provided, allowing arthroscopic surgery on a first side of a device without tissue effects on a back side of the device.
摘要翻译：手术装置包括细长轴，其具有联接到所述轴的第一和第二电隔离电极，使得所述第二电极的暴露部分仅围绕所述细长轴的圆周的一部分设置，并且包括与所述细长轴的近侧间隔开的部分第一电极。另一种手术装置还包括细长轴，其具有联接到所述轴的第一和第二电隔离电极，其中所述轴包括第一侧，并且所述第一和第二电极的暴露表面朝向所述第一侧面朝向。提供“冷却回”的各种实施例，允许在装置的第一侧上进行关节镜手术，而不会在装置的背面产生组织影响。

78. 发明授权

US07400930B2 Method for treating intervertebral discs 有权
标题翻译：治疗椎间盘的方法
公开(公告)号：US07400930B2
公开(公告)日：2008-07-15
申请号：US10712006
申请日：2003-11-14
申请人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
发明人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
IPC分类号： A61N1/06
CPC分类号： A61B17/1671 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/320016 , A61B17/320068 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/08 , A61B18/082 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0133 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09 , A61N1/06 , A61N1/40 , A61N1/403
摘要： A method of manipulating a disc tissue of an intervertebral disc is described, the disc has a nucleus pulposus, an annulus fibrosus, and an inner wall of the annulus fibrosus. The method includes providing a catheter having a radiofrequency electrode at a distal region of the catheter and a proximal region for externally guiding the distal region of the catheter within an intervertebral disc. The method also includes positioning the electrode at the inner wall of the annulus fibrosus by applying a sufficient force to advance the catheter through the nucleus pulposus to the inner wall of the annulus fibrosus. The force is insufficient to puncture the annulus fibrosus. The method further includes delivering energy to the disc tissue using the electrode.
摘要翻译：描述了一种操纵椎间盘的椎间盘组织的方法，该椎间盘具有髓核，纤维环和纤维环的内壁。该方法包括提供在导管的远端区域处具有射频电极的导管和用于在椎间盘内外部引导导管的远侧区域的近端区域。该方法还包括通过施加足够的力将导管穿过髓核推进到纤维环的内壁来将电极定位在纤维环的内壁处。力不足以刺穿纤维环。该方法还包括使用电极将能量递送到盘组织。

79. 发明授权

US06997941B2 Method and apparatus for treating annular fissures in intervertebral discs 失效
标题翻译：用于治疗椎间盘中环状裂缝的方法和装置
公开(公告)号：US06997941B2
公开(公告)日：2006-02-14
申请号：US10388609
申请日：2003-03-17
申请人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
发明人： Hugh R. Sharkey , John Ashley , Joel Saal , Jeffrey A. Saal , Le Trong Le
IPC分类号： A61F7/00
CPC分类号： A61B17/1671 , A61B10/02 , A61B17/00491 , A61B17/29 , A61B17/320016 , A61B17/320068 , A61B17/3203 , A61B17/3421 , A61B17/3496 , A61B17/7061 , A61B17/8836 , A61B18/00 , A61B18/08 , A61B18/082 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1485 , A61B18/1492 , A61B18/18 , A61B18/24 , A61B34/20 , A61B2017/00022 , A61B2017/00084 , A61B2017/0011 , A61B2017/00119 , A61B2017/00261 , A61B2017/00274 , A61B2017/003 , A61B2017/00336 , A61B2017/00455 , A61B2017/00867 , A61B2017/22044 , A61B2017/22049 , A61B2017/22082 , A61B2017/22087 , A61B2017/2905 , A61B2017/2927 , A61B2017/320008 , A61B2017/320044 , A61B2017/3445 , A61B2017/3488 , A61B2018/00011 , A61B2018/00267 , A61B2018/00434 , A61B2018/0044 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00625 , A61B2018/00654 , A61B2018/00702 , A61B2018/00791 , A61B2018/00797 , A61B2018/046 , A61B2018/1266 , A61B2018/1405 , A61B2018/1407 , A61B2018/1425 , A61B2018/1435 , A61B2018/1472 , A61B2018/1807 , A61B2090/0454 , A61B2090/061 , A61B2090/064 , A61B2090/3937 , A61B2217/005 , A61B2218/002 , A61B2218/007 , A61F2/442 , A61F2002/30677 , A61F2007/0298 , A61M25/0084 , A61M25/0133 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M25/09 , A61N1/06 , A61N1/40 , A61N1/403
摘要： A device is described that may be positioned at a location in an intervertebral disc for diagnosis or treatment of the disc. Treatment may include, for example, applying energy or removing material, and may decrease intradiscal pressure. Radiofrequency energy may be applied. A percutaneous method of repairing a fissure in the annulus pulposus comprises placing an energy source adjacent to the fissure and providing sufficient energy to the fissure to raise the temperature to at least about 45-70° C. and for a sufficient time to cause the collagen to weld. An intervertebral fissure also can be treated by placing a catheter with a lumen adjacent to the fissure and injecting sealant into the fissure via the catheter, thereby sealing the fissure. An intervertebral fissure additionally can be treated by providing a catheter having a distal end, a proximal end, a longitudinal axis, and an intradiscal section at the catheter's distal end on which there is at least one functional element. The next step is applying a force longitudinally to the proximal of the catheter which is sufficient to advance the intradiscal section through the nucleus pulposus and around an inner wall of an annulus fibrosus, but which force is insufficient to puncture the annulus fibrosus. Next the functional element is positioned at a selected location of the disc by advancing or retracting the catheter and optionally twisting the proximal end of the catheter. Then the functional unit treats the annular fissure. Optionally, there is an additional step of adding a substance to seal the fissure. An externally guidable intervertebral disc apparatus also is disclosed.
摘要翻译：描述了可以定位在椎间盘中的位置以用于椎间盘的诊断或治疗的装置。治疗可以包括例如施加能量或去除材料，并且可以降低椎间盘内的压力。可以应用射频能量。修复环带中裂缝的经皮方法包括将能量源放置在裂缝附近并为裂缝提供足够的能量以将温度升高至至少约45-70℃，并且足够的时间使胶原蛋白焊接。也可以通过将具有腔的导管放置在裂缝附近并通过导管将密封剂注入到裂缝中，从而密封裂缝来治疗椎间裂。另外可以通过在导管的远端提供具有远端，近端，纵向轴线和椎间盘内节段的导管来治疗椎间裂缝，在该导管的至少一个功能元件上。下一步是向导管的近端施加一个力，这足以使椎间盘内部分通过髓核并绕纤维环的内壁延伸，但是哪个力不足以刺穿纤维环。接下来，功能元件通过前进或缩回导管并且可选地扭转导管的近端来定位在盘的选定位置。然后功能单元处理环形裂缝。任选地，存在添加物质以密封裂缝的附加步骤。还公开了一种外部引导性椎间盘装置。

80. 发明授权

US06878155B2 Method of treating intervertebral disc tissue employing attachment mechanism 失效
标题翻译：使用连接机制治疗椎间盘组织的方法
公开(公告)号：US06878155B2
公开(公告)日：2005-04-12
申请号：US09884859
申请日：2001-06-18
申请人： Hugh R. Sharkey , Sepehr Fariabi , John Ashley , Joel Saal , Jeffrey Saal
发明人： Hugh R. Sharkey , Sepehr Fariabi , John Ashley , Joel Saal , Jeffrey Saal
IPC分类号： A61B18/20 , A61B17/00 , A61B17/16 , A61B17/22 , A61B17/34 , A61B17/56 , A61B18/00 , A61B18/04 , A61B18/12 , A61B18/18 , A61M25/00 , A61M25/01 , A61F7/00 , A61F2/00
CPC分类号： A61B17/1671 , A61B17/3421 , A61B2017/00261 , A61B2017/003 , A61B2017/22044 , A61B2017/22049 , A61B2017/3488 , A61M25/0084 , A61M25/09
摘要： Apparatus and methods are disclosed for accessing the interior of an intervertebral disc to perform a function within the disc. One such apparatus comprises a catheter having a lumen; and a guide wire having a distal portion and a proximal portion, and configured to be positioned within and moved relative to the lumen of the catheter; wherein the guide wire is capable of navigating itself within an intradiscal section of the intervertebral disc to a selected section of the disc and the catheter is capable of being advanced relative to the guide wire such that the catheter follows a path of the guide wire within the intradiscal section of the disc to the selected section. These apparatus and methods may be used for the treatment of intervertebral disc disorders such as sealing fissures of the annulus fibrosus, which may or may not be accompanied with contained or escaped extrusions. These apparatus and methods may also be used, for example, for the removal or addition of material to the intervertebral disc.
摘要翻译：公开了用于访问椎间盘内部以执行椎间盘内的功能的装置和方法。一种这样的装置包括具有内腔的导管; 以及导线，其具有远侧部分和近端部分，并且构造成定位在所述导管的内腔内并相对于所述导管的内腔移动; 其中所述导丝能够在椎间盘的椎间盘内段内自身导航到所述盘的选定部分，并且所述导管能够相对于所述导丝前进，使得所述导管沿着所述导丝的路径盘片的椎间盘内部分到选定的部分。这些装置和方法可以用于治疗椎间盘疾病，例如纤维环纤维的密封裂缝，其可能伴随着包含或逃逸的挤出物，也可能不伴随其中。这些装置和方法也可以用于例如去除或添加到椎间盘的材料。

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