专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

71. 发明公开

EP2762498A1 Modified plant defensin 审中-公开
标题翻译：修饰植物防御素
公开(公告)号：EP2762498A1
公开(公告)日：2014-08-06
申请号：EP13179127.9
申请日：2008-04-18
申请人： Hexima Limited
发明人： Anderson, Marilyn Anne , Heath, Robyn Louise , Lay, Fung Tso , Poon, Simon
IPC分类号： C07K19/00 , C07K14/415 , C07K2/00 , C12N15/62 , C12N15/63 , C12N15/29
CPC分类号： C12N15/8257 , C07K14/415 , C07K2319/00 , C12N15/8282
摘要： The invention herein includes a general method for reducing or eliminating a toxic effect of transgenic defensin expression in a host plant. The invention also includes a method of modifying a nucleic acid encoding a defensin, a nucleic acid modified thereby and a modified defensin encoded by the modified nucleic acid sequence. The invention also includes a transgenic plant containing and expressing the modified defensin-coding nucleic acid sequence, the plant exhibiting reduced or eliminated toxic effects of defensin, compared with otherwise comparable transgenic plants expressing an unmodified defensin. The modified defensin is termed a chimeric defensin having a mature defensin domain of a first plant defensin combined with a C-terminal propeptide domain of a second plant defensin or a vacuolar translocation peptide.
摘要翻译：本发明包括用于减少或消除宿主植物中转基因防御素表达的毒性效应的一般方法。本发明还包括修饰编码防御素的核酸，由其修饰的核酸和由修饰的核酸序列编码的修饰的防御素的方法。本发明还包括含有并表达修饰的防御素编码核酸序列的转基因植物，与其他可比较的表达未修饰防御素的转基因植物相比，该植物表现出降低或消除防御素的毒性作用。修饰的防卫素被称为嵌合防卫素，其具有第一植物防御素的成熟防御素结构域与第二植物防御素的C-末端前肽结构域或液泡转位肽的组合。

72. 发明公开

EP2585095A1 TREATMENT OF PROLIFERATIVE DISEASES 审中-公开
标题翻译：增生性疾病治疗
公开(公告)号：EP2585095A1
公开(公告)日：2013-05-01
申请号：EP11797388.3
申请日：2011-06-23
申请人： Balmoral Australia Pty Ltd , Hexima Limited
发明人： HULETT, Mark Darren , KA HO POON, Ivan , ANDERSON, Marilyn Anne.
IPC分类号： A61K38/16 , A61P35/00 , G01N33/50
CPC分类号： G01N33/5017 , A61K38/168 , G01N2333/415 , G01N2500/10
摘要： The present invention relates to methods for preventing or treating proliferative diseases. In particular, the present invention relates to the use of compositions derived or derivable from plants, such as plant defensins, particularly in methods for the prevention or treatment of proliferative diseases such as cancer. The present invention also relates to associated uses, systems and kits.

73. 发明授权

EP1366168B1 PLANT-DERIVED MOLECULES AND GENETIC SEQUENCES ENCODING SAME AND USES THEREFOR 有权
标题翻译：来自植物的分子和该编码基因序列及其用途
公开(公告)号：EP1366168B1
公开(公告)日：2011-05-18
申请号：EP02710687.1
申请日：2002-02-08
申请人： Hexima Limited
发明人： ANDERSON, Marilyn, Anne , LAY, Fung, Tso , HEATH, Robyn, Louise
IPC分类号： C12N15/29 , C07K14/415
CPC分类号： C12N15/8279 , A01N37/46 , A01N65/20 , A01N65/38 , C07K14/415 , C12N15/8281 , C12N15/8282 , C12N15/8283 , C12N15/8286 , Y02A40/162
摘要： The present invention provides amino acid molecules derived from Nicotiana alata. The present invention contemplates the use of nucleic acids encoding such amino acid molecules in the generation of transgenic plants having resistance or at least reduced sensitivity to plant pests including insects, microorganisms, fungi and/or viruses. The transgenic plants provided by the present invention include monocotyledonous and dicotyledonous plants, and particularly include crop plants and ornamental flowering plants.

74. 发明公开

EP3764798A1 INSECTICIDAL PROTEINS FROM PLANTS AND METHODS FOR THEIR USE 审中-实审
公开(公告)号：EP3764798A1
公开(公告)日：2021-01-20
申请号：EP19766594.6
申请日：2019-03-12
申请人： Pioneer Hi-Bred International, Inc. , Hexima Limited
发明人： LIU, Lu , LUM, Amy , ONG, Azalea S. , SCHEPERS, Eric , UDRANSZKY, Ingrid , ZHONG, Xiaohong
IPC分类号： A01N65/00 , C07K14/415 , C12N15/09 , C12N15/52 , C12N15/62 , C12N15/82

75. 发明授权

EP2673365B1 MODIFIED PLANT DEFENSINS USEFUL AS ANTI-PATHOGENIC AGENTS 失效转让
标题翻译：经修饰的植物防御素可用作抗病原剂
公开(公告)号：EP2673365B1
公开(公告)日：2017-12-20
申请号：EP12744866.0
申请日：2012-02-07
申请人： Hexima Limited
发明人： VAN DER WEERDEN, Nicole , ANDERSON, Marilyn, Anne
IPC分类号： C12N15/62 , C07K14/415 , A61K38/16 , C07K19/00 , C12N15/82
CPC分类号： C12N15/8282 , A01H5/02 , A01H5/06 , A01H5/08 , A01H5/10 , A01H5/12 , A01H6/88 , A01H15/00 , C07K7/06 , C07K14/415 , C07K14/4723 , C07K2319/21 , C07K2319/95
摘要： This disclosure relates generally to the field of anti-pathogenic agents, including a modified defensin molecule with anti-pathogen activity. Genetically modified plants and their progeny or parts expressing or containing the modified defensin and anti-pathogen compositions for use in horticulture and agriculture and as animal and human medicaments are also provided.

76. 发明授权

EP1390503B1 NUCLEIC ACID MOLECULES ENCODING CYCLISABLE AMINO ACID SEQUENCES 有权
标题翻译：核酸分子编码CYCLISIERBARE氨基酸序列
公开(公告)号：EP1390503B1
公开(公告)日：2010-09-29
申请号：EP00972479.0
申请日：2000-11-03
申请人： THE UNIVERSITY OF QUEENSLAND , Hexima Limited
发明人： CRAIK, David, James , ANDERSON, Marilyn, Anne , JENNINGS, Cameron, Victor
IPC分类号： C07K14/415 , C12N15/82 , C12N15/29 , C12N15/62 , C07K16/16
CPC分类号： C07K14/415

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式