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71. 发明公开

EP1845918A1 EYE REGISTRATION SYSTEM FOR REFRACTIVE SURGERY AND ASSOCIATED METHODS 有权
标题翻译： EYES登记制度屈光手术和相关程序
公开(公告)号：EP1845918A1
公开(公告)日：2007-10-24
申请号：EP05825678.5
申请日：2005-11-29
申请人： Alcon RefractiveHorizons, Inc.
发明人： GRAY, Gary, P. , CAMPIN, John, A.
IPC分类号： A61F9/01
CPC分类号： A61F9/008 , A61B3/113 , A61B3/152 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： An orientation method for corrective eye surgery that registers pairs of eye images taken at different times and with the patient in different positions includes retrieving reference digital image data on an eye of the patient, including image data on an extracorneal eye feature. Real-time image data are collected that include image data on the extracorneal eye feature. A combined image is displayed of a superposition of the data sets, and a determination is made as to whether the combined image indicates an adequate registration between them based upon the extracorneal eye feature data in the two data sets. If the registration is not adequate, one of the data sets is manipulated until an adequate registration is achieved. A system is directed to apparatus and software for orienting a corrective program for eye surgery.

72. 发明公开

EP1806116A1 Illumination characteristic selection system for imaging during an ophthalmic laser procedure and associated methods 审中-公开
标题翻译：照明属性选择系统用于成像的眼科激光治疗和相关方法中
公开(公告)号：EP1806116A1
公开(公告)日：2007-07-11
申请号：EP06125849.7
申请日：2006-12-11
申请人： Alcon RefractiveHorizons, Inc.
发明人： LeBlanc, Richard Alan , Campin, John A. , Nguyen, Phuock K.
IPC分类号： A61F9/008
CPC分类号： A61B3/156 , A61F9/008 , A61F2009/00872
摘要： A system (10,10') for optimizing the effects of light sources on viewing and image processing, and for imaging an illuminated object (14) takes advantage of the fact that specularly reflected light has particular polarization properties compared with diffusely scattered light. The system includes a polarized light source (11, 20) to illuminate an object with a polarized beam (19) and an unpolarized light source (12) for delivering unpolarized light to illuminate the object with an unpolarized beam (23). A detector (18) is positioned to receive light from the beams reflected from the object. A polarizer (21) is oriented for substantially filtering out specular reflection from the object and for permitting at least a portion of diffuse reflection from the object to pass therethrough. The polarized and unpolarized light sources (11, 12) and the polarizer (21) are controllable for selectively illuminating the object with and detecting light having a selected polarization characteristic as a function of a portion of a procedure being performed.
摘要翻译：一种系统（10,10“）用于优化的上观看和图像处理的光源的影响，以及用于照亮对象（14）的摄像利用了factthat的镜面反射光具有偏振特性特别是与漫散射光相比。该系统包括一个偏振光源（11，20）以照亮用偏振光束（19）和以非偏振光源（12）用于将非偏振光到对象与在非偏振光束（23）照射所述对象。检测器（18）被定位成从所述对象反射的光束接收光。偏振器（21）被定向为基本上滤除从物体的镜面反射和用于至少允许漫反射的一部分从对象穿过那里。偏振光和非偏振光的光源（11，12）和偏振器（21）是可控制的，用于选择性地照射光的对象，并具有选定的极化特性作为过程的一部分的功能检测来执行。

73. 发明公开

EP1696845A2 HYBRID EYE TRACKING SYSTEM AND ASSOCIATED METHODS 有权
标题翻译： HYBRID眼睛跟踪系统和相关方法
公开(公告)号：EP1696845A2
公开(公告)日：2006-09-06
申请号：EP04815239.1
申请日：2004-12-23
申请人： Alcon RefractiveHorizons, Inc.
发明人： GRAY, Gary , CAMPIN, John, A. , BOTT, Steven, E. , GIBBS, David, Michael , PETTIT, George, H.
IPC分类号： A61F9/01
CPC分类号： A61F9/008 , A61B18/20 , A61B2018/00636 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： A system (10) and method for tracking ocular changes (12, 13) during a surgical procedure include directing an eye-safe optical beam (21) toward an undilated, unparalyzed eye (90). A reflected optical beam (23) is detected (22), and measurements (17) are performed based upon data contained in the reflected optical beam of at least one geometric parameter of the eye at a predetermined frequency (105), and from them is calculated a change in the at least one geometric parameter (106). The calculated change is used to dynamically adjust the directing of laser beam shots (14) during the surgery.

74. 发明公开

EP1529504A1 Method and system for optimising wavefront-guided refractive laser surgery 有权
$Method and system for optimising wavefront-guided refractive laser surgery$
标题翻译： Verfahren und System zur Optimierung wellenfrontgesteuerter refraktiver Laserchirurgie
公开(公告)号：EP1529504A1
公开(公告)日：2005-05-11
申请号：EP04105060.0
申请日：2004-11-01
申请人： Alcon RefractiveHorizons, Inc.
发明人： Campin, John A. , Pettit, George H. , Lefebvre, William T. , Liedel, Kevin K.
IPC分类号： A61F9/01
CPC分类号： A61B3/1015 , A61F9/00806 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088
摘要： A method for optimizing a prescription for laser-ablation corneal treatment achieves the modification of wavefront-based refractive correction data with the use of user/doctor-input nomograms. Data comprising a wavefront description of a patient eye are received (101) and displayed (103) to a user, who can then make modifications (105) to these treatment data. A modification is calculated (106) based upon the desired correction to yield corrected wavefront description data, which are displayed (108, 109, 110) to the user. A system (10) includes a processor (12) and a device (11) for transmitting a wavefront description of a patient eye to the processor. An input device (48) is adapted to receive a desired correction to the wavefront description data. Software (13) is resident on the processor having code segments for implementing the calculations (106) as described.
摘要翻译：用于优化用于激光消融角膜治疗的处方的方法通过使用用户/医生输入列线图来实现基于波阵面的屈光矫正数据的修改。收到包括患者眼睛的波前描述的数据（101）并向用户显示（103），用户可以对这些治疗数据进行修改（105）。基于期望的校正来计算修改（106），以产生校正的波前描述数据，其被显示（108,109,110）给用户。系统（10）包括处理器（12）和用于将病人眼睛的波前描述发送到处理器的设备（11）。输入设备（48）适于接收对波前描述数据的期望校正。软件（13）驻留在具有用于实现所描述的计算（106）的代码段的处理器上。

75. 发明公开

EP1520411A1 IMAGE DEINTERLACING SYSTEM FOR REMOVING MOTION ARTIFACTS AND ASSOCIATED METHODS 有权
标题翻译： IMAGE交错SYSTEM FOR消除运动伪影和相关方法
公开(公告)号：EP1520411A1
公开(公告)日：2005-04-06
申请号：EP03728497.3
申请日：2003-04-22
申请人： Alcon RefractiveHorizons, Inc.
发明人： GRAY, Gary, Paul
IPC分类号： H04N7/01 , H04N7/12 , H04N11/00 , H04N11/20
CPC分类号： H04N7/012
摘要： Deinterlacing is applied to a composite video image that includes alternating even and odd rows of pixels. The even rows form a first image; the odd rows, a second image; these are recorded at different times, introducing a possibility of motion artifact. A first average horizontal intensity difference is computed (105) between the first image and the second image. The first image is offset (106) by one pixel in each horizontal direction to form a horizontally offset image, and another average horizontal intensity difference is computed (107). A minimum average intensity difference is determined (110) from a comparison of the average horizontal intensity differences. The first image is shifted (113) in a horizontal direction determined to achieve the minimum average horizontal intensity difference, and the horizontally shifted first image is combined (114) with the second image to form an imiproved composite image. An analogous series of steps is carried out in a vertical direction.

76. 发明授权

EP1845918B1 EYE REGISTRATION SYSTEM FOR REFRACTIVE SURGERY AND ASSOCIATED METHODS 有权
标题翻译： EYES登记制度屈光手术和相关程序
公开(公告)号：EP1845918B1
公开(公告)日：2012-01-11
申请号：EP05825678.5
申请日：2005-11-29
申请人： Alcon RefractiveHorizons, Inc.
发明人： GRAY, Gary, P. , CAMPIN, John, A.
IPC分类号： A61F9/01
CPC分类号： A61F9/008 , A61B3/113 , A61B3/152 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： An orientation method for corrective eye surgery that registers pairs of eye images taken at different times and with the patient in different positions includes retrieving reference digital image data on an eye of the patient, including image data on an extracorneal eye feature. Real-time image data are collected that include image data on the extracorneal eye feature. A combined image is displayed of a superposition of the data sets, and a determination is made as to whether the combined image indicates an adequate registration between them based upon the extracorneal eye feature data in the two data sets. If the registration is not adequate, one of the data sets is manipulated until an adequate registration is achieved. A system is directed to apparatus and software for orienting a corrective program for eye surgery.

77. 发明公开

EP2139380A1 ADAPTIVE WAVEFRONT MODULATION SYSTEM AND METHOD FOR REFRACTIVE LASER SURGERY 审中-公开
标题翻译：自适应波阵调制系统与方法激光手术难治
公开(公告)号：EP2139380A1
公开(公告)日：2010-01-06
申请号：EP08746403.8
申请日：2008-04-21
申请人： Alcon RefractiveHorizons, Inc.
发明人： PETTIT, George H. , CAMPIN, John A.
IPC分类号： A61B3/103 , A61F9/01
CPC分类号： A61B3/1015 , A61B3/1035 , A61B3/107 , A61F9/008 , A61F9/00806 , A61F2009/00859 , A61F2009/00872 , A61F2009/0088 , G06F19/00
摘要： A method for improving an accuracy of a prescription for laser-ablation corneal treatment includes the step of receiving a set of raw data comprising Hartmann-Shack image data obtained from a plurality of aberrometer measurements of a patient eye. The Hartmann-Shack data can include, for example, a dot pattern image for each measurement. A set of reconstructed wavefront data calculated from the set of raw data for the plurality of aberrometer measurements is also received. Data on a selected component of the set of raw data and in the set of reconstructed wavefront data are compared. If the selected component data differ more than a predetermined amount between the raw data and the reconstructed wavefront data, the raw data can be further manipulated prior to undertaking laser ablation. In addition, these data are removed from consideration for inclusion in the database of treatment outcomes.

78. 发明授权

EP1696845B1 HYBRID EYE TRACKING SYSTEM AND ASSOCIATED METHODS 有权
标题翻译： HYBRID眼睛跟踪系统和相关方法
公开(公告)号：EP1696845B1
公开(公告)日：2009-02-18
申请号：EP04815239.1
申请日：2004-12-23
申请人： Alcon RefractiveHorizons, Inc.
发明人： GRAY, Gary , CAMPIN, John, A. , BOTT, Steven, E. , GIBBS, David, Michael , PETTIT, George, H.
IPC分类号： A61F9/01
CPC分类号： A61F9/008 , A61B18/20 , A61B2018/00636 , A61F9/00804 , A61F2009/00846 , A61F2009/00872
摘要： A system (10) and method for tracking ocular changes (12, 13) during a surgical procedure include directing an eye-safe optical beam (21) toward an undilated, unparalyzed eye (90). A reflected optical beam (23) is detected (22), and measurements (17) are performed based upon data contained in the reflected optical beam of at least one geometric parameter of the eye at a predetermined frequency (105), and from them is calculated a change in the at least one geometric parameter (106). The calculated change is used to dynamically adjust the directing of laser beam shots (14) during the surgery.

79. 发明公开

EP1973206A1 Gas-purged laser system and method thereof 审中-公开
标题翻译： Gasgereinigtes Lasersystem und Verfahrendafür
公开(公告)号：EP1973206A1
公开(公告)日：2008-09-24
申请号：EP08102320.2
申请日：2008-03-05
申请人： Alcon RefractiveHorizons, Inc.
发明人： Pettit, George H. , Downes, George Richard, III , Bott, Steven E.
IPC分类号： H01S3/02 , H01S3/225
CPC分类号： H01S3/02 , A61F9/008 , A61F9/00804 , H01S3/027 , H01S3/225
摘要： A gas-purged laser system (100) and method of gas-purging a laser system are disclosed. One embodiment of the laser system comprises an excimer refractive surgical laser system having a laser beam optical path configured to allow purging of a portion of a volume (140) enclosing the laser beam optical path with a gas, and a gas generator (150), operable to generate the purging gas and provide the gas to the volume portion. The portion of the volume can be the entire volume enclosing the laser beam optical path or a selected portion thereof. The gas can be nitrogen gas and the gas generator can be a self-contained nitrogen generator as will be known to those having skill in the art. Embodiments can further comprise a controller (300) for controlling the flow of purging gas in response to received signals representative of various parameters, such as temperature, oxygen level, pressure, humidity and flow rate.
摘要翻译：公开了一种气体净化激光系统（100）和一种气体吹扫激光系统的方法。激光系统的一个实施例包括准分子折射外科激光系统，其具有被配置为允许用气体吹扫包围激光束光路的体积（140）的一部分的激光束光学路径，以及气体发生器（150）可操作地产生吹扫气体并将气体提供给体积部分。体积的一部分可以是包围激光束光路的整个体积或其选定部分。如本领域技术人员将知道的，气体可以是氮气，气体发生器可以是独立的氮气发生器。实施例还可以包括控制器（300），用于响应于表示各种参数（例如温度，氧气水平，压力，湿度和流量）的接收信号来控制净化气体的流动。

80. 发明公开

EP1909637A2 OPHTHALMIC DEVICE LATERAL POSITIONING SYSTEM AND ASSOCIATED METHODS 有权
标题翻译：侧定位系统的眼科设备和相关操作
公开(公告)号：EP1909637A2
公开(公告)日：2008-04-16
申请号：EP06788496.5
申请日：2006-07-26
申请人： Alcon RefractiveHorizons, Inc.
发明人： CAMPIN, John, A. , BOWES, John, J.
IPC分类号： A61B3/15 , A61F9/01
CPC分类号： A61F9/008 , A61B3/14 , A61B3/145 , A61B3/152 , A61F9/007 , A61F2009/00872
摘要： A system and method for determining a lateral position of an eye relative to an ophthalmic device are disclosed. One embodiment of the method includes receiving data comprising an image of a surface of an eye. An edge feature in the image is located, wherein the edge feature is in a known relationship to a pupil of the eye. The image is mapped from the edge feature to laterally define the pupil, and a center of the pupil is determined using the pupil definition. The pupil center comprises a location from which to achieve a preferred lateral eye position relative to an ophthalmic device. An embodiment of the system of this invention can include a processor and a software package executable by the processor, the software package adapted to cause the processor to carry out the method steps.

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