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71. 发明申请

WO2011020074A9 CORNEAL INLAY WITH NUTRIENT TRANSPORT STRUCTURES 审中-公开
公开(公告)号：WO2011020074A9
公开(公告)日：2011-02-17
申请号：PCT/US2010/045541
申请日：2010-08-13
申请人： ACUFOCUS, INC. , CHRISTIE, Bruce , PETERSON, Edward, W. , VAN DE POL, Corina
发明人： CHRISTIE, Bruce , PETERSON, Edward, W. , VAN DE POL, Corina
IPC分类号： A61F2/14
摘要： Corneal inlays and masks and methods of improving vision of a patient with corneal inlays and masks are provided. Masks with an aperture can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. For example, a mask can have an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion, such as a clear lens or aperture. This provides an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The mask may also include nutrient transport structures that provide nutrient flow through mask to prevent nutrient depletion. These nutrient transport structures can be configured to concentrate nutrient transmission near a center region of the mask to provide more nutrient flow near the center region.

72. 发明申请

WO2011020074A1 CORNEAL INLAY WITH NUTRIENT TRANSPORT STRUCTURES 审中-公开
标题翻译：带有营养运输结构的脊椎内衬
公开(公告)号：WO2011020074A1
公开(公告)日：2011-02-17
申请号：PCT/US2010045541
申请日：2010-08-13
申请人： ACUFOCUS INC , CHRISTIE BRUCE , PETERSON EDWARD W , VAN DE POL CORINA
发明人： CHRISTIE BRUCE , PETERSON EDWARD W , VAN DE POL CORINA
IPC分类号： A61F2/14
CPC分类号： A61F2/15 , A61F2/1451 , A61F2250/0024 , G02C7/046 , G02C7/165
摘要： Corneal inlays and masks and methods of improving vision of a patient with corneal inlays and masks are provided. Masks with an aperture can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. For example, a mask can have an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion, such as a clear lens or aperture. This provides an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The mask may also include nutrient transport structures that provide nutrient flow through mask to prevent nutrient depletion. These nutrient transport structures can be configured to concentrate nutrient transmission near a center region of the mask to provide more nutrient flow near the center region.
摘要翻译：提供角膜嵌体和面罩以及改善角膜嵌体和面罩患者视力的方法。具有孔径的面罩可以改善患者的视力，例如通过增加患者眼睛的焦点深度。例如，掩模可以具有围绕相对高的透射中心部分的相对较低的可见光透射的环形部分，例如透明透镜或光圈。这提供了具有小孔径的环形掩模，用于光通过到视网膜以增加聚焦深度。面罩还可以包括营养输送结构，其提供通过面罩的营养物流以防止营养物质耗尽。这些营养物质运输结构可以被配置为将营养物质传播集中在面罩的中心区域附近，以在中心区域附近提供更多的营养物流。

73. 发明申请

WO2006113377A3 CORNEAL MASK FORMED OF DEGRADATION RESISTANT POLYMER 审中-公开
公开(公告)号：WO2006113377A3
公开(公告)日：2006-10-26
申请号：PCT/US2006/013944
申请日：2006-04-13
申请人： ACUFOCUS, INC. , SILVESTRINI, Thomas, A.
发明人： SILVESTRINI, Thomas, A.
IPC分类号： A61L27/16 , A61F9/007
摘要： Disclosed are masks (34) configured to be implanted in a cornea of a patient. In one embodiment, the body of the mask has a light transmitting portion (38) , a light blocking portion disposed about the light transmitting portion, and an outer periphery surrounding the light blocking portion (36) . The mask is adapted to reside between two intracorneal layers of a cornea. In a preferred embodiment, the mask is formed from a material comprising a highly fluorinated polymeric material and an opacification agent and is resistant to degradation upon exposure to ultraviolet light. In another embodiment, the mask is formed from a material which comprises a polyanionic compound. In some embodiments, the mask includes one or more wound healing modulator compounds to aid in proper healing following implantation.

74. 发明申请

US20230078298A1 TORIC SMALL APERTURE INTRAOCULAR LENS WITH EXTENDED DEPTH OF FOCUS 有权
公开(公告)号：US20230078298A1
公开(公告)日：2023-03-16
申请号：US17886849
申请日：2022-08-12
申请人： AcuFocus, Inc.
发明人： William J. Link , R. Kyle Webb
IPC分类号： A61F2/16
摘要： An intraocular lens is provided that includes a refractive element and a mask. The refractive element has a first power in a first meridian and a second power greater than the first power in a second meridian. A magnitude of the first and second powers and a location of the first and second meridians are configured to correct astigmatism in a human eye. The mask is configured to block a substantial portion of light from passing through an annular region thereof and to permit a substantial portion of light to pass through a central aperture thereof to enhance an astigmatism correction rotational misplacement range and depth of focus.

75. 发明申请

US20220362009A1 INTRAOCULAR IMPLANT WITH REMOVABLE OPTIC 有权
公开(公告)号：US20220362009A1
公开(公告)日：2022-11-17
申请号：US17662599
申请日：2022-05-09
申请人： AcuFocus, Inc.
发明人： R. Kyle Webb
IPC分类号： A61F2/16
摘要： Intraocular implants and methods of forming intraocular implants are described herein. The intraocular implant can include a powered optic and a lens holder. The optic can be mechanically coupled to an inner periphery of the lens holder to form the intraocular implant. A portion of the lens holder can include a mask disposed about the optic to increase depth of focus in a human patient.

76. 发明申请

US20210244532A1 IN SITU ADJUSTABLE OPTICAL MASK 有权
公开(公告)号：US20210244532A1
公开(公告)日：2021-08-12
申请号：US17249045
申请日：2021-02-18
申请人： AcuFocus, Inc.
发明人： Thomas A. Silvestrini
IPC分类号： A61F2/16 , A61F2/14 , G03C1/73 , G02F1/00 , G02F1/01
摘要： Implantable corneal and intraocular implants such as a mask are provided. The mask can improve the vision of a patient, such as by being configured to increase the depth of focus of an eye of a patient. The mask can include an aperture configured to transmit along an optical axis substantially all visible incident light. The mask can further include a transition portion that surrounds at least a portion of the aperture. This portion can be configured to switch from one level of opacity to another level of opacity through the use of a controllably variable absorbance feature such as a switchable photochromic chromophore within a polymer matrix.

77. 发明申请

US20190315081A1 PROCESS FOR MANUFACTURING AN INTRAOCULAR LENS WITH AN EMBEDDED MASK 审中-公开
公开(公告)号：US20190315081A1
公开(公告)日：2019-10-17
申请号：US16250392
申请日：2019-01-17
申请人： AcuFocus, Inc.
发明人： Adam C. Reboul , Patrick H. Benz , R. Kyle Webb
IPC分类号： B29D11/02 , B29C33/12 , A61F2/16 , B29D11/00
摘要： Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a mask adapted to increase depth of focus. The method of manufacturing the implant can include positioning the mask with an aperture on a protruding pin of a positioning mold portion. The protruding pin can be configured to center the mask in the intraocular lens.

78. 发明授权

US10342656B2 Ocular mask having selective spectral transmission 有权
公开(公告)号：US10342656B2
公开(公告)日：2019-07-09
申请号：US15809581
申请日：2017-11-10
申请人： AcuFocus, Inc.
发明人： Abhiram S. Vilupuru , Marie Dvorak Christ
IPC分类号： A61F2/16 , G02C7/02 , A61F2/14 , G02C7/16 , A61F9/04 , A61B3/10
摘要： A mask is provided that is configured to increase the depth of focus of a patient. The mask can include an aperture configured to transmit along an optical axis substantially all visible incident light. The mask can further include a portion surrounding at least a portion of the aperture. The portion may be configured to be substantially opaque to visible electromagnetic radiation and be substantially transparent to electromagnetic radiation transmitted from an ocular examination device (e.g., substantially transparent to at least some non-visible electromagnetic radiation with a wavelength between about 750 nm and about 1500 nm).

79. 发明授权

US09848979B2 Ocular mask having selective spectral transmission 有权
公开(公告)号：US09848979B2
公开(公告)日：2017-12-26
申请号：US15377891
申请日：2016-12-13
申请人： AcuFocus, Inc.
发明人： Abhiram S. Vilupuru , Marie Dvorak Christ
IPC分类号： A61F2/16 , G02C7/02 , A61F2/14 , A61F9/04 , A61B3/10 , G02C7/16
CPC分类号： A61F2/1451 , A61B3/102 , A61F2/14 , A61F2/145 , A61F2/15 , A61F2/16 , A61F2/1613 , A61F2/1659 , A61F9/04 , A61F2250/0036 , A61F2250/0053 , G02C7/165
摘要： A mask is provided that is configured to increase the depth of focus of a patient. The mask can include an aperture configured to transmit along an optical axis substantially all visible incident light. The mask can further include a portion surrounding at least a portion of the aperture. The portion may be configured to be substantially opaque to visible electromagnetic radiation and be substantially transparent to electromagnetic radiation transmitted from an ocular examination device (e.g., substantially transparent to at least some non-visible electromagnetic radiation with a wavelength between about 750 nm and about 1500 nm).

80. 发明申请

US20170144392A1 PROCESS FOR MANUFACTURING AN INTRAOCULAR LENS WITH AN EMBEDDED MASK 有权
公开(公告)号：US20170144392A1
公开(公告)日：2017-05-25
申请号：US15427456
申请日：2017-02-08
申请人： AcuFocus, Inc.
发明人： Adam C. Reboul , Patrick H. Benz , R. Kyle Webb
IPC分类号： B29D11/02 , A61F2/16 , B29D11/00
CPC分类号： B29D11/023 , A61F2/16 , A61F2002/1681 , A61F2230/0006 , B29C33/123 , B29D11/00442 , B29D11/0048 , B29K2627/16 , B29K2995/0093
摘要： Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a mask adapted to increase depth of focus. The method of manufacturing the implant can include positioning the mask with an aperture on a protruding pin of a positioning mold portion. The protruding pin can be configured to center the mask in the intraocular lens.

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