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71. 发明专利

JP5069540B2 Electron spectroscopy composite device, and electron spectroscopy method 有权
公开(公告)号：JP5069540B2
公开(公告)日：2012-11-07
申请号：JP2007293391
申请日：2007-11-12
申请人：学校法人福岡大学 , 株式会社コベルコ科研 , 株式会社神戸製鋼所
发明人：修司松尾 , 孝渡部 , 久伸脇田
IPC分类号： G01N23/227
摘要： PROBLEM TO BE SOLVED: To provide an electron spectrometer and an electron spectroscopy method for easily obtaining accurate information on an electron structure and a local structure of the chemical species for forming a surface or an interface of a single-layer or multi-layer solid sample. SOLUTION: The electron spectrometer is provided with: a vacuum vessel 11; a sample holding section 13a for holding the sample 12 within the vacuum vessel 11; an X ray source 31 disposed in a position of the vacuum vessel 11 in which a measurement point 12b of the sample 12 is viewed, and irradiating the measurement point 12b with X rays; an ultraviolet ray source 32 for irradiating it with ultraviolet rays; a plurality of electron beam sources 33 for irradiating electron beams; and an electron energy analyzer 40 for detecting photoelectrons emitted from the sample 12 by irradiating it with the X rays, the ultraviolet rays or the electron beams, or electrons scattered by the sample 12. A plurality of the electron beam sources 33, 33, ... are disposed so as to cause incident angles of the electron beams to be different relative to a sample surface 12a. COPYRIGHT: (C)2009,JPO&INPIT

72. 发明专利

JP5055644B2 Implementation evaluation structure and implementation evaluation method 有权
公开(公告)号：JP5055644B2
公开(公告)日：2012-10-24
申请号：JP2008221949
申请日：2008-08-29
申请人：学校法人福岡大学 , 株式会社ウォルツ , 財団法人福岡県産業・科学技術振興財団
发明人：肇友景 , 整堀内 , 順森下
IPC分类号： H01L21/60
CPC分类号： H01L2924/0002 , H01L2924/00

73. 发明专利

JP2012088146A Method for quantifying 2-arachidonoyl glycerol 审中-公开
标题翻译：定量2-ARACHIDONOYL GLYCEROL的方法
公开(公告)号：JP2012088146A
公开(公告)日：2012-05-10
申请号：JP2010234486
申请日：2010-10-19
申请人： Fukuoka Univ , 学校法人福岡大学
发明人： IRIE KEIICHI , FUJIWARA MICHIHIRO , MISHIMA KENICHI , HIGUCHI SEI , MISHIMA KENJI , HAYAKAWA KAZUHIDE , SANO KAZUNORI , SATO ASAMITSU , AKITAKE YOSHIHARU , ARAKI MAIKO , TAIJI MAKIKO
IPC分类号： G01N30/88 , G01N1/10 , G01N1/28 , G01N27/62 , G01N30/06 , G01N30/72
摘要： PROBLEM TO BE SOLVED: To provide a method for measuring and quantifying 2-arachidonoyl glycerol (2-AG) without substantially changing 2-AG in a biological sample into 1-AG.SOLUTION: The method enables direct quantification of 2-AG without substantially changing 2-AG into 1-AG by purifying 2-AG in a biological sample with an aprotic solvent such as acetone, tetrahydrofuran, methyl ethyl ketone, or acrylonitrile. Since 2-AG in a biological sample can be directly quantified, 2-AG level in a brain which increases in a stepwise manner with high-fat diet intake can be measured, which allows preference for fat to be found early. It is expected that this may lead to the development of a medicament or a food product for prophylaxis of obesity.
摘要翻译：要解决的问题：提供一种用于测量和定量2-花生四烯酰甘油（2-AG）而不将生物样品中的2-AG基本上改变为1-AG的方法。解决方案：通过用非质子溶剂如丙酮，四氢呋喃，甲基乙基酮或丙烯腈纯化生物样品中的2-AG，该方法能够直接定量2-AG而基本上不将2-AG改变成1-AG。由于可以直接量化生物样品中的2-AG，因此可以测量以高脂肪饮食摄取方式逐步增加的脑中的2-AG水平，这允许早期发现脂肪的优先选择。预期这可能导致用于预防肥胖症的药物或食品的开发。版权所有（C）2012，JPO＆INPIT

74. 发明专利

JP2012072074A Treating agent for hepatopathy 审中-公开
标题翻译：治疗药物用于治疗
公开(公告)号：JP2012072074A
公开(公告)日：2012-04-12
申请号：JP2010216736
申请日：2010-09-28
申请人： Fukuoka Univ , 学校法人福岡大学
发明人： ENJOJI MUNECHIKA , TAKADA JIRO , NAKAJIMA MANABU , MACHIDA KAZUYUKI , OSADA NAMI , NISHINAKAGAWA TAKUYA , KOGA MOMOKO
IPC分类号： A61K31/353 , A61P1/16 , C07D311/72
摘要： PROBLEM TO BE SOLVED: To provide a treating agent for hepatopathy containing a tocopherol aminoalkyl carboxylic acid ester having a substituent on the N atom and/or a salt thereof.SOLUTION: The tocopherol aminoalkyl carboxylic acid ester having a substituent on the N atom or the salt thereof has been found to show an improving effect on the degenerative hepatocyte death, and also to show an improving effect on hepatopathy even in macroscopic findings and tissue findings of the liver and can be effectively used as a treating agent for hepatopathy.
摘要翻译：待解决的问题：提供一种含有在N原子上具有取代基的生育酚氨基烷基羧酸酯和/或其盐的肝病治疗剂。解决方案：已经发现在N原子上具有取代基的生育酚氨基烷基羧酸酯或其盐对退行性肝细胞死亡显示出改善的作用，并且即使在宏观发现中也显示出对肝病的改善作用，肝脏的组织发现可以有效地用作肝病的治疗剂。版权所有（C）2012，JPO＆INPIT

75. 发明专利

JP2012066997A Acid-resistant repairing material and repairing method using the same 有权
标题翻译：耐酸修复材料及其修复方法
公开(公告)号：JP2012066997A
公开(公告)日：2012-04-05
申请号：JP2011181638
申请日：2011-08-23
申请人： Fukuoka Univ , Kyushu Electric Power Co Inc , Nishi Nippon Gijutsu Kaihatsu Kk , 九州電力株式会社 , 学校法人福岡大学 , 西日本技術開発株式会社
发明人： DAN HIROSHI , ASHIDA HIROKI , SOEDA MASASHI , ETO YOSHITAKE , KUSUNOKI SADANORI
IPC分类号： C04B28/08 , C04B18/08 , C04B18/10 , E04G23/02
CPC分类号： Y02W30/92
摘要： PROBLEM TO BE SOLVED: To provide a low-cost repairing material having excellent acid resistance and excellent applicability, and a repairing method using the material, by combining multi-purpose and generally used materials with high environmental load reducing effect and PFBC ash as a byproduct of a pressurized-fluidized bed combined generation type thermal power plant, without using special materials such as polymer-based organic materials or alumina cement.SOLUTION: The acid-resistant repairing material is made by mixing 95-105 pts.mass blast furnace cement type B, 36-53 pts.mass fly ash and 396-540 pts.mass fine aggregate for 100 pts.mass PFBC ash. And in the repairing method, mixing is made with 10-12 pts.mass water in which an admixture is suitably added to the 100 pts.mass acid-resistant repairing material within a range where required applicability can be obtained.
摘要翻译：要解决的问题：为了提供具有优异耐酸性和优异适用性的低成本修复材料，以及使用该材料的修复方法，通过组合具有高环境负荷降低效果的多用途和一般使用的材料以及PFBC灰作为加压流化床组合发电型火力发电厂的副产物，不使用特殊材料如聚合物基有机材料或氧化铝水泥。
解决方案：耐酸修补材料是通过混合95-105 pts.mass高炉水泥B型，36-53 pts.mass粉煤灰和396-540 pts.mass细骨料100 pts.mass PFBC 灰。在修补方法中，用10〜12质量份的水进行混合，其中在可以获得所需适用性的范围内，将100重量份的耐酸性修补材料适当地添加到混合物中。版权所有（C）2012，JPO＆INPIT

76. 发明专利

JP2012043651A Three-dimensional image measuring device and three-dimensional image measuring method 有权
标题翻译：三维图像测量装置和三维图像测量方法
公开(公告)号：JP2012043651A
公开(公告)日：2012-03-01
申请号：JP2010184024
申请日：2010-08-19
申请人： Fukuoka Pref Gov Sangyo Kagaku Gijutsu Shinko Zaidan , Fukuoka Univ , 学校法人福岡大学 , 財団法人福岡県産業・科学技術振興財団
发明人： TOMOKAGE HAJIME , SUEYOSHI HARUKI
IPC分类号： H01J37/28 , G01B15/08 , G01N23/225
摘要： PROBLEM TO BE SOLVED: To provide a three-dimensional image measuring device capable of specifying flow portions and failure portions of a semiconductor device and a device system using a three-dimensional current image.SOLUTION: A three-dimensional image measuring device 100 comprises a scanning circuit 24 for outputting scanning signals to a scanning mirror 23, an optical axial direction moving mechanism 26 for changing a relative distance between a specimen 200 and a second objective lens 25 in an optical axial direction by moving the second objective lens 25 along the optical axis, an optical axial direction movement control circuit 27 for outputting control signals to the optical axial direction moving mechanism 26, a conductive probe 31 for outputting induced current flowing through the specimen 200, and an operation part 43 for constructing a two-dimensional current image of the specimen 200 based on the scanning signals from the scanning circuit 24 and a current value from the conductive probe 31, and constructing a three-dimensional image to which each of the two-dimension current images is overlaid at each relative distance changed by the optical axial direction moving mechanism 26.
摘要翻译：要解决的问题：提供一种能够指定半导体器件的流动部分和故障部分以及使用三维当前图像的器件系统的三维图像测量装置。解决方案：三维图像测量装置100包括用于将扫描信号输出到扫描镜23的扫描电路24，用于改变样本200和第二物镜25之间的相对距离的光轴方向移动机构26 沿着光轴移动第二物镜25的光轴方向的光轴方向移动控制电路27，用于向光轴方向移动机构26输出控制信号的光轴方向移动控制电路27，用于输出流过试样的感应电流的导电探针31 200，以及用于根据来自扫描电路24的扫描信号和来自导电探针31的电流值构成样本200的二维电流图像的操作部43，并构成三维图像，在由光轴向移动机构26改变的每个相对距离处重叠两维电流图像 PYRIGHT：（C）2012，JPO＆INPIT

77. 发明专利

JP2012009613A Wiring board formation method, and wiring board 有权
标题翻译：接线板形成方法和接线板
公开(公告)号：JP2012009613A
公开(公告)日：2012-01-12
申请号：JP2010144057
申请日：2010-06-24
申请人： Fukuoka Pref Gov Sangyo Kagaku Gijutsu Shinko Zaidan , Fukuoka Univ , Nippon Steel Chem Co Ltd , 学校法人福岡大学 , 新日鐵化学株式会社 , 財団法人福岡県産業・科学技術振興財団
发明人： TOMOKAGE HAJIME , FUJISHIRO KOICHI , ITAHARA SHUNEI , SAITO TORU , HAYASHI SHIGEHIRO
IPC分类号： H01L23/12 , H01L23/14 , H05K3/10
摘要： PROBLEM TO BE SOLVED: To provide a wiring board formation method and the like capable of significantly reducing labor and cost for manufacturing a wiring board, by forming a decoupling capacitor at the same time a wiring pattern is formed.SOLUTION: The wiring board formation method includes steps of: forming cylindrical via insulation parts 3a and 3b and via conduction parts 4a and 4b on a silicon substrate 2; forming an induction part 5a by extending an insulation material which is laminated on a peripheral region of the via conduction part 4a to be connected to a tubular end part of the via insulation part 3a across the entire circumference; forming an insulation part 5b by extending the insulation material laminated in the peripheral region of the via conduction part 4b so that a portion does not come in contact with the tubular end part of the via insulation part 3b; and forming wiring parts 6a and 6b which are connected to the via conduction parts 4a and 4b while being laminated on surfaces of the induction part 5a and the insulation part 5b. The wiring part 6a is connected to a power source, the wiring part 6b is connected to the ground, and then the wiring part 6a and the silicon substrate 2 sandwich the induction part 5a to form a capacitor.
摘要翻译：解决问题的方案为了提供能够显着降低制造布线板的人力和成本的布线基板的形成方法等，通过在形成布线图案的同时形成去耦电容器。线路板形成方法包括以下步骤：在硅衬底2上形成圆柱形通孔绝缘部分3a和3b以及通过导电部分4a和4b; 通过延伸绝缘材料形成感应部分5a，所述绝缘材料层压在通孔导电部分4a的周边区域上，以连接到通孔绝缘部分3a的整个圆周上的管状端部; 通过使层叠在通路导通部4b的周边区域的绝缘材料延伸而形成绝缘部5b，使得部分不与通孔绝缘部3b的管状端部接触; 以及在层压在感应部5a和绝缘部5b的表面上的同时形成与通孔导通部4a，4b连接的配线部6a，6b。布线部分6a连接到电源，布线部分6b连接到地，然后布线部分6a和硅基片2夹着感应部分5a形成电容器。版权所有（C）2012，JPO＆INPIT

78. 发明专利

JP2011220969A Method for detecting proliferative diabetic retinopathy and method for screening preventive and treating agent 有权
标题翻译：检测增殖性糖尿病的方法及筛选预防和治疗药物的方法
公开(公告)号：JP2011220969A
公开(公告)日：2011-11-04
申请号：JP2010093240
申请日：2010-04-14
申请人： Fukuoka Univ , Saga Univ , 国立大学法人佐賀大学 , 学校法人福岡大学
发明人： IZUHARA KENJI , OTA SHOICHIRO , ARIMA KAZUHIKO , SHIRAISHI YUJI , SUZUKI SHOICHI , MUKONO TOSHIHIRO , YOSHIDA SHIGEO , ISHIBASHI TATSURO
IPC分类号： G01N33/50 , G01N33/15 , G01N33/53 , G01N33/68
摘要： PROBLEM TO BE SOLVED: To provide a detecting method for proliferative diabetic retinopathy using a marker and a screening method for preventive and treating agent for proliferative diabetic retinopathy.SOLUTION: A detecting method for proliferative diabetic includes measuring an expression level of periostin gene, an expression of periostin protein, or an amount of periostin protein in biological sample derived from a test subject. A screening method for proliferative diabetic retinopathy includes measuring an expression level of periostin gene or an amount of periostin protein when a cell which can produce periostin is cultured in the presence of a candidate substance.
摘要翻译：待解决的问题：提供使用标记物的增殖性糖尿病视网膜病变的检测方法和增殖性糖尿病性视网膜病变的预防和治疗剂的筛选方法。解决方案：增殖性糖尿病的检测方法包括测定源自测试对象的生物样品中骨膜素基因的表达水平，骨膜素蛋白的表达或骨膜素蛋白的量。增殖性糖尿病视网膜病变的筛选方法包括在候选物质的存在下培养可产生骨膜素的细胞时，测定骨膜素基因的表达量或骨膜素蛋白的量。版权所有（C）2012，JPO＆INPIT

79. 发明专利

JP2011154018A Method for prediabetes screening 有权
标题翻译：预测方法筛选
公开(公告)号：JP2011154018A
公开(公告)日：2011-08-11
申请号：JP2010246867
申请日：2010-11-02
申请人： Fukuoka Univ , Nof Corp , 学校法人福岡大学 , 日油株式会社
发明人： WATANABE TOSHIAKI
IPC分类号： G01N33/53 , G01N33/543
CPC分类号： C07D239/42 , G01N33/6812 , G01N2800/042
摘要： PROBLEM TO BE SOLVED: To provide a method for prediabetes screening by means of measurement of argpyrimidine in blood. SOLUTION: By the method for prediabetes screening by means of measurement of argpyrimidine in blood, a compound including argpyrimidine structure expressed by formula (I) is measured by a specific antibody. In the formula, R 1 indicates a hydrogen atom, a hydroxy group, a protein residue, or a peptide residue, and R 2 indicates a hydrogen atom, an acetyl group, a protein residue, or a peptide residue. COPYRIGHT: (C)2011,JPO&INPIT

80. 发明专利

JP2011107033A Fluorous sialic acid derivative and analysis method therefor 有权
标题翻译：氟化物酸性衍生物及其分析方法
公开(公告)号：JP2011107033A
公开(公告)日：2011-06-02
申请号：JP2009264030
申请日：2009-11-19
申请人： Fukuoka Univ , 学校法人福岡大学
发明人： HAYAMA TADASHI , YAMAGUCHI MASATOSHI , NODA HITOSHI , YOSHIDA HIDEYUKI , TODOROKI KENICHIRO , ITOYAMA MIKI , SAKAGUCHI YOHEI
IPC分类号： G01N30/88 , C07H7/033 , G01N27/62 , G01N30/06 , G01N30/72
摘要： PROBLEM TO BE SOLVED: To provide a detection method of a fluorous sialic acid derivative which is detected by an LC-MS/MS method. SOLUTION: A fluorous sialic acid derivative can be detected by an LC-MS/MS method, and is represented by general formula [I] äin the formula, R 1 is a glycolyl group, or the like, R 2 , R 3 , R 4 are each hydrogen atom or the like, Ph is a phenylene group, a is an integer of 1-3, b is an integer of 0 or 1, c is an integer of 1-3, and Rf is a fluoroalkyl group represented by general formula [II] (in the formula, R 9 , R 10 are each an hydrogen atom or a fluorine atom, and d is an integer of 4-10.)}. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供通过LC-MS / MS方法检测的唾液酸衍生物的检测方法。解决方案：可以通过LC-MS / MS方法检测氟唾液酸衍生物，并且由通式[I]表示，其中R 1是乙酰基，或 R SB 3，R SB 3，R SB 4，各自为氢原子等，Ph为亚苯基，a为整数，为1-3，b为0或1的整数，c为1-3的整数，Rf为通式[II]表示的氟代烷基（式中，R SB为9 ，R SB 10，各自为氢原子或氟原子，d为4-10的整数。}}。版权所有（C）2011，JPO＆INPIT

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