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71. 发明申请

WO2008014489A2 SYSTEM AND METHOD FOR DISTRIBUTING MEDICATION AND MONITORING MEDICATION PROTOCOL COMPLIANCE 审中-公开
标题翻译：用于分配药物和监测药物协议的系统和方法
公开(公告)号：WO2008014489A2
公开(公告)日：2008-01-31
申请号：PCT/US2007/074656
申请日：2007-07-27
申请人： MADOR, Jack
发明人： MADOR, Jack
IPC分类号： G07F11/40 , G08B21/24
CPC分类号： G08B5/40 , A61J1/035 , A61J7/0436 , A61J7/0481 , A61J2200/30 , G06F19/00 , G06F19/3462 , G07F11/40 , G07F17/0092
摘要： A system and method of distributing supplements and medicines while monitoring compliance with a medicine protocol describing a schedule of when the individual doses are to taken. By way of example, a pill card is adapted with frangible compartments for retaining supplements and medicines. Sensors coupled to the frangible compartments detect access to the retained pills. A controller monitors access to the pills and communicates access or schedule issues within a local monitoring device and/or external systems or parties. In one embodiment, the seal attached on the exterior of each pill compartment incorporates a frangible conductor that is broken upon pressing the pills through the membrane, wherein access is thus sensed. Depending on application, feedback (e.g., reminders, compliance alerts, and the like) are provided by the pill card, local monitoring device, or external means in response to data generated by the pill card.
摘要翻译：一种分发补充剂和药物的系统和方法，同时监测对药物方案的遵守情况，该药物方案描述了何时采取个别剂量的时间表。举例来说，药片卡适应于易碎的隔间以保留补充剂和药物。传感器耦合到易碎的隔间，可以检测到残留的药片。控制器监视对药片的访问，并传达本地监视设备和/或外部系统或方内的访问或调度问题。在一个实施例中，附接在每个药丸隔室的外部上的密封件包含易碎的导体，其在通过膜挤压药丸时被破坏，因此感测到进入。根据应用，响应于药丸卡产生的数据，药片卡，本地监测装置或外部装置提供反馈（例如，提示，合规警报等）。

72. 发明申请

WO2007140481A3 HEART ASSIST DEVICE 审中-公开
公开(公告)号：WO2007140481A3
公开(公告)日：2007-12-06
申请号：PCT/US2007/070155
申请日：2007-05-31
申请人： WAMPLER, Richard
发明人： WAMPLER, Richard
IPC分类号： A61M1/10
摘要： A heart assist device comprising a rotary pump housing having a cylindrical bore, a pumping chamber and a motor stator including an electrically conductive coil located within the housing and surrounding a portion of the cylindrical bore. A rotor has a cylindrical shaft, at least one impeller appended to one end of the shaft, and a plurality of magnets located within the shaft. The rotor shaft is positioned within the housing bore with the magnets opposite the motor stator, and the impeller is positioned within the pumping chamber. The housing bore is closely fitted to the outer surface of the shaft forming a hydrodynamic journal bearing, with the pumping chamber and journal bearing connected by a leak path of blood flow between the pumping chamber and the journal bearing. A backiron of the motor stator attracts the rotor magnets to resist longitudinal displacement of the rotor within the housing during operation. The relative orientation of positions of the inflow, outflow, and leakage flow paths may be varied within the pump, such as to accommodate different intended methods for implantation and/or use.

73. 发明申请

WO2007098493A3 LARGE-AREA FLAT-PANEL PHOTON DETECTOR WITH HEMISPHERICAL PIXELS AND FULL AREA COVERAGE 审中-公开
公开(公告)号：WO2007098493A3
公开(公告)日：2007-08-30
申请号：PCT/US2007/062616
申请日：2007-02-22
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , FERENC, Daniel
发明人： FERENC, Daniel
IPC分类号： H01J43/30 , H01L31/00
摘要： A photo detector with a flat panel vacuum enclosure with a window including hemispherical cavities coated with photocathode material to convert photons into photoelectrons. The electrons are focused from the hemispherical photocathodes to their centers where they are detected in small electron sensors. Reflectors in dead areas between the hemispheres direct light to the active hemispherical photocathodes which leads to full area coverage. The result is that the entire panel surface is active in photon detection, and the information is concentrated to a very small area of the electron sensors. A voltage plate simultaneously distributes the anode and cathode potentials to all of the pixels in the panel. In one embodiment, the photoelectrons are detected with a scintillator and Geiger-mode avalanche photodiodes (G-APD).

74. 发明申请

WO2007092097A2 FUNCTIONALIZED INORGANIC FILMS FOR ION CONDUCTION 审中-公开
标题翻译：用于离子导入的功能化无机膜
公开(公告)号：WO2007092097A2
公开(公告)日：2007-08-16
申请号：PCT/US2006/061500
申请日：2006-12-01
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , CHMELKA, Bradley, F. , ATHENS, George, L.
发明人： CHMELKA, Bradley, F. , ATHENS, George, L.
CPC分类号： C08J5/22 , B01D67/0048 , B01D67/0088 , B01D67/0093 , B01D69/10 , B01D69/105 , B01D71/027 , B01D2323/38 , B01D2325/14 , C08J2383/02 , H01B1/06 , H01M8/1016 , H01M2300/0068
摘要： Novel membranes based on functionalized porous inorganic materials for ion exchange and conduction have been synthesized and characterized. The preparation procedure of these new membranes involves the synthesis of porous inorganic films, into which hydrophilic moieties are incorporated along the interior pore surfaces of the inorganic framework. Ion-conducting species are grafted into the pores via reactions with surface groups of the inorganic framework to allow for ion transport through the pore network.
摘要翻译：已经合成了基于用于离子交换和传导的官能化多孔无机材料的新型膜。这些新膜的制备方法涉及多孔无机膜的合成，其中亲水部分沿着无机骨架的内孔表面并入其中。离子导电物质通过与无机骨架的表面基团的反应接枝到孔中，以允许离子通过孔网络传输。

75. 发明申请

WO2007081353A3 HYDRO CYANO AND CYANO FULLERENE DERIVATIVES 审中-公开
公开(公告)号：WO2007081353A3
公开(公告)日：2007-07-19
申请号：PCT/US2006/005637
申请日：2006-02-17
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , WUDL, Fred , STUCKY, Galen, D. , WANG, Hengbin , JOUSSELME, Bruno
发明人： WUDL, Fred , STUCKY, Galen, D. , WANG, Hengbin , JOUSSELME, Bruno
IPC分类号： C01B31/00 , B82B1/00
摘要： The components of and a proton conducting membrane (PCM) produced from a host polymer and an attached or physically blended in hydrogen cyano fullerene proton-source agent, with the physical blending of the host polymer and hydrogen cyano fullerene further promoted by a poly(ethylene oxide) attached fullerene mixing agent.

76. 发明申请

WO2007078326A1 CONTROLLED PUPIL DILATION FOR DIAGNOSTIC AND TREATMENT OF VISUAL ANOMALIES 审中-公开
标题翻译：用于诊断和治疗视觉异常的控制对位放大器
公开(公告)号：WO2007078326A1
公开(公告)日：2007-07-12
申请号：PCT/US2006/024140
申请日：2006-06-19
申请人： LEWIS, Rick
发明人： LEWIS, Rick
IPC分类号： A61P27/00 , A61P27/02 , A61P27/06 , A61P27/08 , A61F9/00 , A61F9/007
CPC分类号： A61K31/137 , A61K9/0048 , A61K31/4174
摘要： Methods and compositions are disclosed for topically applying an ophthalmic solution to the eye to at least temporarily reduce the effects of various visual anomalies. The solution contains a therapeutically effective amount of one or more pupil dilating agents that generate a moderate amount of dilation in order to relieve symptoms such as vitreous floaters. Moreover, the composition may be topically applied in approximately a one drop dose, which may be instilled on an as needed basis depending on the concentration and rate of release of one or more of the following or similar dilating agents: naphazoline, ephedrine, naphazoline HCI, phenylephrine HCI, epinephrine and/or dipivefrin.
摘要翻译：公开了用于将眼用溶液局部施用于眼睛以至少暂时降低各种视觉异常的影响的方法和组合物。溶液含有治疗有效量的一种或多种瞳孔扩张剂，其产生中度量的扩张以便缓解诸如玻璃体浮游物的症状。此外，组合物可以以大约一滴的剂量局部施用，其可以根据需要滴注，这取决于一种或多种以下或类似的扩张剂的释放的浓度和速率：萘甲唑啉，麻黄碱，萘唑啉HCl ，去氧肾上腺素HCl，肾上腺素和/或dipiffrin。

77. 发明申请

WO2007047644A3 METHOD FOR MICROCHANNEL SURFACE MODIFICATION 审中-公开
公开(公告)号：WO2007047644A3
公开(公告)日：2007-04-26
申请号：PCT/US2006/040505
申请日：2006-10-13
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , TSENG, Hsian-Rong , SUI, Guodong , WANG, Jinji
发明人： TSENG, Hsian-Rong , SUI, Guodong , WANG, Jinji
IPC分类号： B05D5/00 , B05D3/00
摘要： A method (10) for functionalizing microfluidic channels with specific characteristics by the introduction of hydroxyl groups onto the surface area of the channel using a solution of an acid and a peroxide (30) followed by a reaction of an essentially pure siloxane-based reagent (60) and a funtional group (70). Chemically modified channel surfaces can be designed to prevent non-specific binding or interaction of biological samples with the channel surfaces; surface wetting or dewetting with the control of the hydrophobicity and hydrophilicity of the channel surfaces; confer solvent resistance by attaching inert molecules to the interior channel; and tethering molecules that have available amine, thiol, isocyanato and isothiocyanato or similar groups to permit the attachment of biomolecules to channel surfaces.

78. 发明申请

WO2007024841A2 REFLUX RESISTANT CANNULA AND SYSTEM FOR CHRONIC DELIVERY OF THERAPEUTIC AGENTS USING CONVECTION-ENHANCED DELIVERY 审中-公开
标题翻译：使用对流增强运输方式治疗药物的抗转基因肛门和系统
公开(公告)号：WO2007024841A2
公开(公告)日：2007-03-01
申请号：PCT/US2006/032740
申请日：2006-08-21
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , BANKIEWICZ, Krystof, S.
发明人： BANKIEWICZ, Krystof, S.
IPC分类号： A62C11/00
CPC分类号： A61M25/0023 , A61M25/02 , A61M25/0606 , A61M25/0662 , A61M2025/028 , A61M2025/0286 , A61M2025/0681 , A61M2210/0693
摘要： A step-design cannula and delivery system for chronic delivery of therapeutic substances into the brain using convention-enhanced delivery of therapeutic substances and which effectively prevents reflux in vivo and maximizes distribution in the brain.
摘要翻译：一种步骤设计的插管和递送系统，用于使用治疗物质的常规增强递送将治疗物质慢性递送到脑中，并有效地防止体内反流并使脑中的分布最大化。

79. 发明申请

WO2007022359A2 VERTICAL INTEGRATED SILICON NANOWIRE FIELD EFFECT TRANSISTORS AND METHODS OF FABRICATION 审中-公开
标题翻译：垂直集成硅纳米管场效应晶体管及其制造方法
公开(公告)号：WO2007022359A2
公开(公告)日：2007-02-22
申请号：PCT/US2006/032153
申请日：2006-08-16
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , YANG, Peidong , GOLDBERGER, Joshua , HOCHBAUM, Allon , FAN, Rong , HE, Rongrui
发明人： YANG, Peidong , GOLDBERGER, Joshua , HOCHBAUM, Allon , FAN, Rong , HE, Rongrui
IPC分类号： H01L21/00
CPC分类号： H01L29/78642 , B82Y10/00 , H01L21/823487 , H01L21/84 , H01L27/1203 , H01L27/1292 , H01L29/045 , H01L29/0665 , H01L29/0673 , H01L29/0676 , H01L29/42392 , H01L29/66772 , H01L29/78684 , H01L29/78687 , H01L29/78696
摘要： Vertical integrated field effect transistor circuits and methods are described which are fabricated from Silicon, Germanium, or a combination Silicon and Germanium based on nanowires grown in place on the substrate. By way of example, vertical integrated transistors are formed from one or more nanowires which have been insulated, had a gate deposited thereon, and to which a drain is coupled to the exposed tips of one or more of the nanowires. The nanowires are preferably grown over a surface or according to a desired pattern in response to dispersing metal nanoclusters over the desired portions of the substrate. In one preferred implementation, SiCI4 is utilized as a gas phase precursor during the nanowire growth process. In place nanowire growth is also taught in conjunction with structures, such as trenches, while bridging forms of nanowires are also described.
摘要翻译：描述了基于硅，锗或基于在衬底上生长的纳米线的硅和锗的组合制造的垂直集成场效应晶体管电路和方法。作为示例，垂直集成晶体管由已经绝缘的一个或多个纳米线形成，栅极沉积在其上，并且漏极耦合到一个或多个纳米线的暴露尖端。响应于将金属纳米簇分散在基底的所需部分上，纳米线优选在表面上或根据期望的图案生长。在一个优选的实施方案中，SiCl 4在纳米线生长过程中用作气相前体。就纳米线生长而言，还结合诸如沟槽的结构教导，同时还描述了纳米线的桥接形式。

80. 发明申请

WO2006135780A1 FAST DUAL-VDD BUFFER INSERTION AND BUFFERED TREE CONSTRUCTION FOR POWER MINIMIZATION 审中-公开
标题翻译：快速双VDD缓冲器插入和缓冲树结构用于功率最小化
公开(公告)号：WO2006135780A1
公开(公告)日：2006-12-21
申请号：PCT/US2006/022543
申请日：2006-06-09
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , HE, Lei
发明人： HE, Lei
IPC分类号： G06F17/50
CPC分类号： G06F17/505
摘要： Integrated circuit apparatus and methods are described for inserting multi- V dd buffers within an interconnection tree during routing toward minimization of power under a delay constraint. Insertion of level converters is not necessary within the routing trees of the interconnect tree despite the insertion of the multi- V dd buffers. Techniques are described for controlling the dramatic complexity increment due to simultaneous delay and power consideration and increased buffer choices. Overhead reduction techniques are taught including: sampling based techniques, prediction based pruning techniques (PSP) and (PMP), and escape grid reduction, each of which are directed to multi- V dd buffer insertion. The resultant integrated circuits are routed with substantial power reductions over conventional routing.
摘要翻译：描述了用于插入多V DD的集成电路装置和方法

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